Mechanism of Yin-Qin oral liquid for treatment of COVID-19 based on network pharmacology by Shi-Liang JI, Li-Ping HE, Dong-Kai GUO, Wei WANG, Hui CHEN, Yi-Guo JIANG, Cheng WANG

“…Through UniProt, GeneCards database convert Target and gene, and then Cytoscape3.7.2 was used to construct the “active-target” networks and perform topological analysis, The core targets were analyzed by GO and KEGG functional enrichment analysis by R software.Results The network analysis indicated that 56 active ingredients affected 266 key target proteins, and the key targets involve PTGS1, GSK3β, NCOA2, ESR1, ESR2, etc. …”
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Implementation of Psychotherapeutic in Islamic Education by Furi Aristyasari Yunita, Mustaqim Abdul, Ichsan, Azhar Chusnul

“…Psychotherapy is more than just a cure; it is also a means of preventing and constructing personality. The method of this study is a literature method through searching for various related references. …”
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Petiveria alliacea and Caesalpinia spinosa extracts reduce the generation of cancer-associated fibroblasts in a 3D platform representative of the tumor microenvironment by María Camila Jimenez, Paola Lasso, Susana Fiorentino, Alfonso Barreto

“…However, efficiently modeling the generation of CAFs in the tumor microenvironment is challenging. Methods We constructed a 3D structure of the tumor microenvironment (TME), which we refer to as “TME spheroids”. …”
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A Versatile Strategy for Production of Membrane Proteins with Diverse Topologies: Application to Investigation of Bacterial Homologues of Human Divalent Metal Ion and Nucleoside Tr... by Cheng Ma, Zhenyu Hao, Gerard Huysmans, Amelia Lesiuk, Per Bullough, Yingying Wang, Mark Bartlam, Simon E Phillips, James D Young, Adrian Goldman, Stephen A Baldwin, Vincent L G Postis

“…To circumvent this problem we have employed a novel strategy to enable the rapid production of constructs bearing a range of different affinity tags compatible with either cytoplasmic or periplasmic attachment. …”
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Identification and multi-omics analysis of essential coding and long non-coding genes in colorectal cancer by Yanguo Li, Zixing Meng, Chengjiang Fan, Hao Rong, Yang Xi, Qi Liao

“…Then, 29 essential long non-coding genes (ESLs) were predicted using Hypergeometric Test (HT) and Personalized PageRank (PPR) algorithms based on ESPs and co-expressed network constructed from scRNA-seq. CRISPR/Cas9 knockout experiment verified the effect of several ESPs and ESLs on the survival of CRC cell line. …”
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Psoralen-mediated regulation of osteogenic differentiation of periodontal ligament stem cells: involvement of the mTOR pathway by Yujia Wang, Hongbo Zhang, Jie Yu, Jin Jing, Zhaojiang Fu, Yuanping Hao, Qihang Huang, Ruibin Ma, Yingjie Xu, Yingtao Wu

“…Pso-loaded mesoporous polydopamine (MPDA-Pso) nanoparticles were constructed and evaluated in vitro, and in vivo osteogenesis was assessed in rats with alveolar bone defects.ResultsNetwork pharmacology analysis revealed that the mammalian target of rapamycin (mTOR) was a potential target of Pso, and Pso significantly modulated the expression levels of mTOR in PDLSCs and markedly enhanced osteogenic differentiation. …”
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Real time counting method for coal mine drill pipes based on deep learning by Fukai ZHANG, Yiran SUN, Xufeng WU, Aijun LI, Peiyang LI, Dengke WANG, Guan YUAN, Shan ZHAO, Haiyan ZHANG

“…Firstly, collect the working video of the drilling rig from the real monitoring footage of the coal mine underground, annotate and construct the Coal Mine drill Pipe Counting image dataset CMDPC; Then, an improved drilling rig recognition model Drill-YOLOv8 is constructed, which enhances the feature extraction ability of the backbone network for drilling rig targets by introducing triplet attention. …”
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Providing care to refugees through mainstream general practice in the southern health region of New Zealand: a qualitative study of primary healthcare professionals’ perspectives by Tim Stokes, Lauralie Richard, Chrystal Jaye, Georgia Richardson

“…Participants included nine general practitioners and six practice nurses.Results Three analytical constructs were identified: relational engagement with refugees, refugee healthcare delivery and providers’ professional role shaped by complexity. …”
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Fabrication of composite ceramic polymeric membranes for agricultural wastewater treatment by Neamatalla M. Azzam, Sahar S. Ali, Gehad G. Mohamed, Mohamed M. Omar, Shereen K. Amin

“…A ceramic supporting (CS) filter constructed from ball clay, kaolin, feldspar, and quartz using corn starch flour as a pore-developing agent. …”
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Llama antibody fragments recognizing various epitopes of the CD4bs neutralize a broad range of HIV-1 subtypes A, B and C. by Nika Strokappe, Agnieszka Szynol, Marlèn Aasa-Chapman, Andrea Gorlani, Anna Forsman Quigley, David Lutje Hulsik, Lei Chen, Robin Weiss, Hans de Haard, Theo Verrips

“…A panel of VHH, which interfere with CD4 binding to HIV-1 Env were selected with use of panning. …”
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Identifying areas of high invasion risk: a general model and an application to Mexico by Ek del-Val, Patricia Balvanera, Fabiana Castellarini, Francisco Javier Espinosa-García, Miguel Murguía, Carlos Pacheco

“…We produced 5 maps, one for each variable and another constructed with our model of combined risk, for a grid of 0.5º × 0.5º grid across the whole country. …”
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A microbead-enhanced electrochemical platform for β-amyloid peptide (1–42) detection by Claudia do Amaral Razzino, Claudia do Amaral Razzino, Lívia Flório Sgobbi, Juliana Cancino-Bernardi, Angelica Maria Mazuera Zapata, Clara Cardoso Costa, Valtencir Zucolotto, Lucia Vieira, Anderson Oliveira Lobo

“…In this study, we developed an amperometric immunosensor based on magnetic beads as the platform for constructing the immunosensor. Monoclonal antibodies are immobilized on the MBs, enabling selective detection of Aβ1-42. …”
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GeoAI Dataset for Training a Deep Learning-based GEMS Snow Detection Model by Jin-Woo Yu, Jun-Hyeok Jung, Kyoung-Hee Kang, Yong-Mi Lee, Hyung-Sup Jung

“…In this research, we constructed input data using GEMS Level 1C data and generated label data based on GEMS, Advanced Meteorological Imager, and MODIS snow cover data. …”
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Predicted and final tooth position assessment following indirect bonding planned by a digital system by Fernando César MOREIRA, Helder Baldi JACOB, Guilherme dos Reis Pereira JANSON, Daniela Gamba GARIB

“…Digital models (Predicted and Treated) of each patient were superimposed, and referential geometric planes were constructed for linear and angular measurements: arch perimeter, arch depth, intercanine and intermolar widths, mesiodistal crown angulation, and buccolingual crown inclination. …”
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Non-Redox-Based Electrochemical Detection of Adrenaline: A Simple and Reliable Approach Using Glass Nanopipets by Ralph J. Page, Gene Koifman, Noel Manring, Jessica L. Smeltz, Pavithra Pathirathna

“…We systematically studied Adr transfer in various media, including KCl, DI water, Millipore DI water, and Tris buffer, and constructed calibration curves based on peak potential shifts that follow a power-law relationship with Adr concentration. …”
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Development of a sugar-derived silver nanoparticle-based electrochemical immunosensor for sensitive D-dimer detection by Fatma Ozturk Kirbay, İdris Yazgan, Dilek Odaci

“…The immunosensor is constructed by electrodeposition of lactose methoxide aniline silver nanoparticles (LMA-AgNPs) on a screen-printed carbon electrode (SPCE). …”
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A New Pallet-Positioning Method Based on a Lightweight Component Segmentation Network for AGV Toward Intelligent Warehousing by Bin Wu, Shijie Wang, Yi Lu, Yang Yi, Di Jiang, Mengmeng Qiao

“…The results show that by extracting intermediate-, low-, and high-level features from dual-branch input images and integrating them to construct multi-scale images, precise segmentation of various types of pallets can be achieved with limited annotated images. …”
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Immune Evasion Mechanism Mediated by ITPRIPL1 and Its Prognostic Implications in Glioma by Zou Xiaoyun, Ye Wenhao, Wu Huan, Yang Yuanyuan, Liu Changqing, Wen Hebao, Ma Caiyun

“…A nomogram was subsequently constructed and validated to assess the integrated prognostic impact of ITPRIPL1 expression on glioma patients. …”
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Super‐Enhancer–Driven Syndecan‐4 Regulates Intercellular Communication in Hypoxic Pulmonary Hypertension by Xiaoying Wang, Xiangrui Zhu, Wei Huang, Zhaosi Wang, Jian Mei, Langlin Ou, Yunwei Chen, Cui Ma, Lixin Zhang

“…Methods and Results We used serotype 5 adenovirus‐associated virus to interfere with syndecan‐4 and constructed an SU5416 combined with hypoxia–PH model. …”
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Multi-Channel Speech Enhancement Using Labelled Random Finite Sets and a Neural Beamformer in Cocktail Party Scenario by Jayanta Datta, Ali Dehghan Firoozabadi, David Zabala-Blanco, Francisco R. Castillo-Soria

“…The input dataset for this neural architecture is constructed by applying multi-source tracking using multi-sensor generalized labeled multi-Bernoulli (MS-GLMB) filtering, which belongs to the labeled RFS framework, to obtain estimations of the sources’ positions and the associated labels (corresponding to each source) at each time frame with high accuracy under the effect of undesirable factors like reverberation and background noise. …”
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