Global landscape and trends in lifetime risks of haematologic malignancies in 185 countries: population-based estimates from GLOBOCAN 2022Research in context by Kexin Sun, Hongliang Wu, Qian Zhu, Kai Gu, Hui Wei, Shaoming Wang, Li Li, Chunxiao Wu, Ru Chen, Yi Pang, Bingfeng Han, Hongmei Zeng, Meicen Liu, Rongshou Zheng, Wenqiang Wei

“…Methods: We retrieved incidence and mortality rates for Hodgkin lymphoma (HL), Non-Hodgkin lymphoma (NHL), multiple myeloma (MM) and leukaemia from GLOBOCAN 2022 of 185 countries, along with the national population statistics and all-cause mortality data sourced from the United Nations. For trend analysis, we obtained consecutive cancer registry data spanning from 2003 to 2017 from the Cancer Incidence in Five Continents (CI5) Plus database. …”
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Gene content of seawater microbes is a strong predictor of water chemistry across the Great Barrier Reef by Marko Terzin, Steven J. Robbins, Sara C. Bell, Kim-Anh Lê Cao, Renee K. Gruber, Pedro R. Frade, Nicole S. Webster, Yun Kit Yeoh, David G. Bourne, Patrick W. Laffy

“…Microbial indicator analysis has centered around measuring the taxonomic composition of seawater microbial communities, but this can obscure heterogeneity of gene content between taxonomically similar microbes, and thus, microbial functional genes have been hypothesized to have more scope for predictive potential, though empirical validation for this hypothesis is still pending. …”
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Dynamics of the gut microbiome in subjects challenged with Shigella sonnei 53G in a controlled human infection model by Zachary Liechty, Arianna Baldwin, Sandra Isidean, Akamol Suvarnapunya, Robert Frenck, Chad Porter, Michael Goodson

“…Perturbations in microbial composition during infection and antibiotic treatment were significantly larger in individuals diagnosed with shigellosis than in those who were not. …”
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TDP-43 pathology is associated with divergent protein profiles in ALS brain and spinal cord by Emily Feneberg, Alexander G. Thompson, Philip D. Charles, Iolanda Vendrell, Benedikt M. Kessler, Roman Fischer, Olaf Ansorge, Elizabeth Gray, Kevin Talbot, Martin R. Turner

“…The broader protein composition of these inclusions is of major importance to understanding pathogenesis, clinical heterogeneity and biomarker development. …”
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Baseline fibroblast growth factor 23 predicts incident heart failure and cardiovascular mortality in patients with chronic kidney disease: A 3-year follow-up study by Ying Wang, Dingxin Zhang, Runzhe Zhou, Xiangjie Yang, Xiaoxia Wang, Yuxin Jiang, Xinyuan Zhou, Dashan Li, Jin Zhang, Yonggui Wu

“…Background: Heart failure (HF) is a significant cause of death among patients with chronic kidney disease (CKD). Emerging data suggest a crucial role of fibroblast growth factor 23 (FGF23) in the pathogenesis of HF in CKD patients. …”
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Carotenoid Supplementation in Poultry Nutrition: Canthaxanthin’s Role in Improving Egg Yolk Pigmentation and Production Efficiency by Baluh Medyabrata Atmaja, Rifqi Hidayatulloh, Muhammad Irvan Ali, Amelia Lulu Rosalin Hutabarat, Alief Rahmania Safitri, Abdul Muta Ali, Wenni Meika Lestari

“…A total of 180 Isa Brown hens were assigned to three dietary treatments: a control group (T0: commercial feed), a low Canthaxanthin supplementation group (T1: commercial feed + 60 g/ton feed Canthaxanthin), and a high supplementation group (T2: commercial feed + 120 g/ton feed Canthaxanthin). The data were analyzed using SPSS software (version 25.00), and a one-way analysis of variance (ANOVA) was performed to assess the effects of Canthaxanthin supplementation on laying performance and egg quality, with significance set at p<0.05. …”
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Gut Microbiome Diversity and Uric Acid in Serum and Urine by Cecilie Ness, Dmitri Svistounov, Marit D. Solbu, Natalia Petrenya, Neoma Boardman, Kirsti Ytrehus, Trond G. Jenssen, Andrew Holmes, Stephen J. Simpson, Svetlana N. Zykova

“…Dietary data were collected, and dietary patterns were identified using principal component analysis. …”
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Gut microbiota characteristics in neonatal respiratory distress syndrome and the therapeutic potential of probiotics in recovery by Yongcheng Fu, Xiujuan Wang, Lintao Nie, Zhaorui Wang, Xiao Ma, Lijia Wu, Liping Han, Wenjun Fu, Ruoming Wang, Hongyan Ren, Da Zhang, Juan Ding

“…Notably, the abundance of bacteria such as Muribaculaceae Incertae Sedis, Rhodococcus, and Corynebacterium was significantly higher in the NRDS group, which may contribute to disease progression. ROC analysis suggested that gut microbiota could serve as potential biomarkers for diagnosing NRDS. …”
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Characteristics and indication of hydrocarbon-generating organisms in sub-salt Majiagou Formation of well T112, central and eastern Ordos Basin by Yinuo ZHANG, Dongdong ZHANG, Liubin WEI, Wenhui LIU, Pingping SHI, Xiaofeng WANG, Qian ZHANG, Yining LI, Zhicheng JIN

“…The fifth member (Ma 5 member) contained more planktonic algae, the fourth member (Ma 4 member) was dominated by benthic algae, and the third member (Ma 3 member) predominantly contained mineral bituminous groundmass. Geochemical data indicated higher total organic carbon (TOC) content in the Ma 3 and Ma 5 members, with minimal variations in organic carbon isotope compositions. …”
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The effects of perfluoroalkyl substance pollution on microbial community and key metabolic pathways in the Pearl River Estuary by Wei Lin, Junlin Zhao, Xingqi Wu, Jiakun Jiang, Chunyang Zhou, Jiating Zheng, Cheng Zhang, Ying Guo, Li Wang, How Yong Ng, Song Li, Shengrui Wang

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Interplay between the gut microbiome and typhoid fever: insights from endemic countries and a controlled human infection model by Philip M. Ashton, Leonardos Mageiros, James E. Meiring, Angeziwa Chunga-Chirambo, Farhana Khanam, Sabina Dongol, Happy Banda, Abhilasha Karkey, Lorena Preciado-Llanes, Helena Thomaides-Brears, Malick Gibani, Nazmul Hasan Rajib, Nazia Rahman, Prasanta Kumar Biswas, Md Amirul Islam Bhuiyan, Sally Kay, Kate Auger, Olivier Seret, Nicholas R. Thomson, Andrew J. Pollard, Stephen Baker, Buddha Basnyat, John D. Clemens, Christiane Dolecek, Sarah J. Dunstan, Gordon Dougan, Robert S. Heyderman, Virginia E. Pitzer, Firdausi Qadri, Melita A. Gordon, Kathryn E. Holt, Thomas C. Darton, STRATAA Study Group

“…The putative protection provided by microbiome SCFA metabolism was supported by data from a controlled human infection model conducted in a UK population, in which participants who did not develop typhoid fever following ingestion of S. …”
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Unveiling IRF4-steered regulation of context-dependent effector programs in CD4+ T cells under Th17- and Treg-skewing conditions by Anna Gabele, Maximilian Sprang, Mert Cihan, Mareen Welzel, Assel Nurbekova, Karolina Romaniuk, Sarah Dietzen, Matthias Klein, Georg Bündgen, Maxim Emelianov, Gregory Harms, Krishnaraj Rajalingam, Tanja Ziesmann, Katrin Pape, Beatrice Wasser, David Gomez-Zepeda, Kathrin Braband, Michael Delacher, Niels Lemmermann, Stefan Bittner, Miguel A. Andrade-Navarro, Stefan Tenzer, Katja Luck, Tobias Bopp, Ute Distler

“…However, the molecular mechanisms of how IRF4 steers diverse transcriptional programs in Th17 and Treg cells are far from being definitive. Here, we integrated data derived from affinity-purification and full mass-spectrometry-based proteome analysis with chromatin immunoprecipitation sequencing. …”
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Reduced scapular neck impingement in 145° neck-shaft angle semi-inlay compared with 155° neck-shaft angle inlay reverse total shoulder arthroplasty during active external rotation... by Itaru Kawashima, MD, PhD, Norimasa Takahashi, MD, PhD, Keisuke Matsuki, MD, PhD, Ryo Haraguchi, MD, Hayato Ryoki, MD, Thomas W. Wright, MD, Scott A. Banks, PhD

“…Based on the 3-dimensional kinematics of the implants, the closest distance between the scapular neck and polyethylene insert was computed. The data from 10° internal rotation to 50° external rotation were used for analysis. …”
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The Structure of Acute Exotoxicosis During the First Three Months of the COVID-19 Pandemic (According to the Acute Toxicosis Department of N.V. Sklifosovsky Research Institute for... by M. V. Belova, K. K. Ilyashenko, A. Yu. Simonova, M. M. Potskhveriya, G. V. Trusov

“…The Statistica 10.0 program was used for data processing.  RESUlTS The total number and gender composition of patients with acute poisonings (AP) did not differ significantly in the compared periods. …”
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Gut-Microbiome Signatures Predicting Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer: A Systematic Review by Ielmina Domilescu, Bogdan Miutescu, Florin George Horhat, Alina Popescu, Camelia Nica, Ana Maria Ghiuchici, Eyad Gadour, Ioan Sîrbu, Delia Hutanu

“…Narrative synthesis and random-effects proportion meta-analysis were performed where data were homogeneous. …”
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Impact of HbA1c variability and time‐in‐range fluctuations on large and small nerve fiber dysfunction in well‐controlled type 2 diabetes: A prospective cohort observational study... by Yun‐Ru Lai, Wen‐Chan Chiu, Ben‐Chung Cheng, I‐Hsun Yu, Ting‐Yin Lin, Hui‐Ching Chiang, Chun‐En Aurea Kuo, Cheng‐Hsien Lu

“…Results Linear regression analysis adjusted for age, diabetes duration, and renal function revealed strong correlations between HbA1c ARV, TIR ARV, and diabetes duration. …”
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Synthesis and Characterization of Hydroxyapatite Assisted by Microwave-Ultrasound from Eggshells for Use as a Carrier of Forchlorfenuron and In Silico and In Vitro Evaluation by Benjamín I. Romero-De La Rosa, Silvia P. Paredes-Carrera, Jorge A. Mendoza-Pérez, Dulce E. Nicolás-Álvarez, Vicente Garibay-Febles, Carlos A. Camacho-Olguin

“…This sample was subsequently used as a carrier for the plant hormone forchlorfenuron (FCF), forming the composite Hap-FCF. Comprehensive characterization was conducted using X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), specific surface area analysis (BET method), zeta potential (ZP), scanning electron microscopy (SEM), and bright-field transmission electron microscopy (BFTEM), ensuring reliable and robust data. …”
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Petrological controls on the engineering properties of carbonate aggregates through a machine learning approach by Javid Hussain, Tehseen Zafar, Xiaodong Fu, Nafees Ali, Jian Chen, Fabrizio Frontalini, Jabir Hussain, Xiao Lina, George Kontakiotis, Olga Koumoutsakou

“…The analysis identified clay, calcite, feldspar, and dolomite as the primary determinants for the engineering behavior of carbonate aggregates. …”
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Utilizing plasma biochemical indicators to improve prediction of economic traits in crossbred duck population by Jian Hu, Mengdie Wang, Linxi Zhu, Chengming Han, Qinglei Yang, Zhenlin Liu, Jing Song, Zhengkui Zhou, Shuisheng Hou, Wentao Cai

“…These findings highlight the potential of plasma biomarkers as auxiliary traits for genomic selection, particularly in optimizing feed efficiency and carcass composition, while underscoring the need for trait-specific model strategies.…”
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EFNA2 Mediates Stiffness-Regulated Hypopharyngeal Cancer Progression by Songqun Hu, Yuanru Liu, Min Cheng, Min Xu, Huiting Liu, Ying Shan, Haosheng Ni, Tian Xia, Qicheng Zhang, Zhenxin Zhang, Bo You

“…Methods Immunohistochemical analysis and cervical enhanced computed tomography (CT) data were used to evaluate correlations among CT values, matrix stiffness, and prognosis, and to develop a prognostic model for HPC. …”
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