Abatacept versus tocilizumab for the treatment of rheumatoid arthritis in TNF inhibitor inadequate responders: study protocol of the SUNSTAR randomised controlled open-label superi... by Bruno Fautrel, Pascal Richette, Christian Roux, Grégoire Cormier, Martin Soubrier, Xavier Mariette, Christophe Richez, Jacques-Eric Gottenberg, Hubert Marotte, Jacques Morel, Rene-Marc Flipo, Jerome Avouac, Athan Baillet, Gael Mouterde, Anne Tournadre, Marie-Elise Truchetet, Sebastien Ottaviani, Tristan Pascart, Thierry Lequerre, Elisabeth Gervais, Luca Semerano, André Basch, Edouard Pertuiset, Jean-Hugues Salmon, Eric Houvenagel, VÉRONIQUE BREUIL, Marie Vandecandelaere, Olivier Vittecocq, Isabelle Griffoul, Charlotte Jauffret, Vincent Ducoulombier, Laurène Norberciak, Jean-Guillaume Letarouilly, Slim Lassoued, Renaud Desbarbieux, Hélène Luraschi, Thibault Rabin, Gauthier Marchasson, Catherine Godart, Nicolas Taisne

“…Which non-TNFi bDMARD administered subcutaneously to allow for ambulatory management to choose in case of first line TNFi inadequate response has not been tested in a randomised clinical trial, while observational data support a potential superiority of tocilizumab over abatacept.Methods and analysis The SUNSTAR (SUbcutaNeouS Tocilizumab vs Abatacept in TNF Alpha inadequate responders for the treatment of Rheumatoid arthritis) study is a 52-week prospective, randomised, multicentre, open-label, superiority phase IV trial comparing subcutaneous tocilizumab with abatacept in a 1:1 ratio. …”
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Development and Assessment of a Soft Wearable for sEMG-Based Hand Grip Detection and Control of a Virtual Environment by Lohith Chatragadda, Aiden Fletcher, Sam Zhong, Fabian A. Vargas, Nishtha Bhagat, Kunal Mankodiya, Matthew J. Delmonico, Dhaval Solanki

“…Methods: We prototyped a three-component wearable system consisting of an e-textile forearm band (E-band), data acquisition module (DAM), and a computer game. …”
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Problems and Prospects for the Application of Neural Networks for the Sphere of Education by T. M. Shamsutdinova

“…This example illustrates the possibility of using a neural network to select further nodes of the educational trajectory based on the available data on the current learning parameters in an electronic course. …”
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The effect of probiotics, prebiotics and synbiotics on gut microbial community profile in overweight and obese Latin American and Caribbean populations: a systematic review of huma... by Manahil M. Bineid, Litai Liu, Eduard F. Ventura, Sakshi Bansal, Katherine Curi-Quinto, Juana del Valle-Mendoza, Gemma E. Walton, Karani Santhanakrishnan Vimaleswaran

“…The findings indicate that the available data are inadequate to establish definitive conclusions regarding the impact of biotic treatments on gut microbiota profiles in LACP. …”
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HD 35843: A Sun-like Star Hosting a Long-period Sub-Neptune and Inner Super-Earth by Katharine Hesse, Ismael Mireles, François Bouchy, Diana Dragomir, Solène Ulmer-Moll, Nora L. Eisner, Keivan G. Stassun, Samuel N. Quinn, Hugh P. Osborn, Sergio G. Sousa, Cristilyn N. Watkins, Karen A. Collins, Edward M. Bryant, Jonathan M. Irwin, Coel Hellier, Marshall C. Johnson, Carl Ziegler, Steve B. Howell, David R. Anderson, Daniel Bayliss, Allyson Bieryla, César Briceño, R. Paul Butler, David Charbonneau, Ryan Cloutier, Jeffrey Crane, Jason Dittmann, Jason D. Eastman, Sebastián A. Freigeiro, Benjamin J. Fulton, Samuel Gill, Maximilian Günther, Haedam Im, Jon M. Jenkins, Michelle Kunimoto, Baptiste Lavie, Monika Lendl, Michael B. Lund, Andrew W. Mann, Belinda Nicholson, David Osip, Martin Paegert, Nuno C. Santos, Richard P. Schwarz, Sara Seager, Stephen Shectman, Johanna Teske, Joseph D. Twicken, Stéphane Udry, Vincent Van Eylen, José Vinés, Sharon X. Wang, Peter J. Wheatley, Joshua N. Winn, Edward E. Zuidema

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The Effects of Solid-State Fermentation by <i>Aspergillus</i> spp. on the Nutritional Profile of Selected Agro-Industrial by-Products as Potential Feedstuffs for Weaner Rabbits by Adedoyin Titi Amos, Damilola Uthman Kareem, Tolulope Modupe Adeleye, Emmanuel Abiodun Adeyeye, Munirat Olaide Abatan, Olusola Sarah Ayorinde, Esther Oluwasayo Adeboye, Maicon Sbardella, Adeboye Olusesan Fafiolu, Abimbola Oladele Oso, Olusegun Mark Obafemi Idowu

“…Digestible energy and digestibility coefficient of gross energy were calculated. Data were subjected to two-way analysis of variance (ANOVA). …”
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Polyethylene terephthalate microplastics affect gut microbiota distribution and intestinal damage in mice by Xiangying Sun, Yin Zhuang, Yubang Wang, Zhenbo Zhang, Lihui An, Qiujin Xu

“…In addition, gut microbiota analysis revealed that the diversity and community composition were altered after PET-MPs exposure, suggesting a metabolic disorder. …”
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Making a Real-Time IoT Network Intrusion-Detection System (INIDS) Using a Realistic BoT–IoT Dataset with Multiple Machine-Learning Classifiers by Jawad Ashraf, Ghulam Musa Raza, Byung-Seo Kim, Abdul Wahid, Hye-Young Kim

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Enhanced vehicle routing for medical waste management via hybrid deep reinforcement learning and optimization algorithms by Norhan Khallaf, Osama Abd-El Rouf, Abeer D. Algarni, Mohy Hadhoud, Ahmed Kafafy

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Meta-Ensemble Learning for Heart Disease Prediction: A Stacking-Based Approach With Explainable AI by Mehwish Naz, Aqsa Khalid, Abdul Hameed, Rabia Taj, Waleed Mumtaz, Faiz Abdullah Alotaibi, Mrim M. Alnfiai

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Unveiling smart contract vulnerabilities: Toward profiling smart contract vulnerabilities using enhanced genetic algorithm and generating benchmark dataset by Sepideh HajiHosseinKhani, Arash Habibi Lashkari, Ali Mizani Oskui

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Broadening the <i>PHIP</i>-Associated Neurodevelopmental Phenotype by Giulia Pascolini, Giovanni Luca Scaglione, Balasubramanian Chandramouli, Daniele Castiglia, Giovanni Di Zenzo, Biagio Didona

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‘Reduced’ HUNT model outperforms NLST and NELSON study criteria in predicting lung cancer in the Danish screening trial by Oluf Dimitri Røe, Maria Markaki, Ioannis Tsamardinos, Vincenzo Lagani, Olav Toai Duc Nguyen, Jesper Holst Pedersen, Zaigham Saghir, Haseem Gary Ashraf

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A Polar-Coded PAPR Reduction Scheme Based On Hybrid Index Modulation by Si-Yu Zhang, Xinwei Yue, Behnam Shahrrava, Yuexia Zhang, Gongpu Wang

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Exploration of machine learning approaches for automated crop disease detection by Annu Singla, Ashima Nehra, Kamaldeep Joshi, Ajit Kumar, Narendra Tuteja, Rajeev K. Varshney, Sarvajeet Singh Gill, Ritu Gill

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Temporal Dynamics of Functional Connectivity in Temporal and Extra-Temporal Lobe Epilepsy: A Magnetoencephalography-Based Study by Suhas M.V, N. Mariyappa, Karunakar Kotegar, Ravindranadh Chowdary M, Raghavendra K, Ajay Asranna, Viswanathan L.G, Sanjib Sinha, Anitha H

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Janus kinase inhibitors in palmoplantar pustulosis: a mixed-methods feasibility (JAKPPPOT) trial protocol by Weiyu Ye, Suzie Cro, James B Galloway, Sarah Chapman, C H Smith, Kingsley Powell, Jonathan Barker, Ann Naylor, Helen McAteer, John Gregory, David Gleeson, April Qin, Jade Pizzato, Manpreet K Sagoo, Lucy Moorhead, Andrew E Pink, Richard Woolf, Satveer K Mahil

“…The primary outcome will be a composite assessment of feasibility across three domains: recruitment, adherence and acceptability, using a mixed-methods analysis approach. …”
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Measurement report: In-depth characterization of ship emissions during operations in a Mediterranean port by L. Le Berre, L. Le Berre, L. Le Berre, B. Temime-Roussel, G. M. Lanzafame, B. D'Anna, N. Marchand, S. Sauvage, S. Sauvage, M. Dufresne, L. Tinel, T. Leonardis, J. Ferreira de Brito, A. Armengaud, G. Gille, L. Lanzi, R. Bourjot, H. Wortham

“…<p>A summertime field campaign was conducted in Marseille, one of the major cruise and ferry ports in the Mediterranean, to provide comprehensive analysis of in-port ship emissions. High-temporal-resolution data were simultaneously collected from two monitoring stations deployed in the port area to examine the composition in both the gas and the particulate phases. …”
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Arterial stiffness, high fasting glucose, and fatty liver as risk factors for visceral obesity in middle-aged Chinese individuals: a cross-sectional study by Hajime Nawata, Li Ou, Xu Zhang, Qinglan Song, Jing Huang, Jin Hu, Kazue Ito, Shinichi Obo, Takeharu Fukushima, Kaori Iwami, Shizuka Iguchi, Ai Igarashi, Xiaoyang He, Jing Zhang, Yu Xia, Ken Takasaki

“…This study aimed to identify independent risk factors for VFA ≥100 cm2 in middle-aged Chinese individuals from the general population. We analyzed data from 148 participants (mean age: 49.3 ± 10.8 years; 54% male) who underwent health check-ups. …”
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Eco-Efficient Biosorbent Based on Leucaena leucocephala Residues for the Simultaneous Removal of Pb(II) and Cd(II) Ions from Water System: Sorption and Mechanism by C. A. Cimá-Mukul, Youness Abdellaoui, Mohamed Abatal, Joel Vargas, Arlette A. Santiago, Jesús Alberto Barrón-Zambrano

“…Further analysis using ATR-FTIR after adsorption contact of biosorbent was also investigated. …”
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