EFFECT OF SOLID DISPERSIONS ON THE SOLUBILITY OF METRONIDAZOLE by I. I. Krasnyuk (Jr.), S. R. Naryshkin, I. I. Krasnyuk, A. V. Belyatskaya, O. I. Stepanova, I. S. Bobrov, V. G. Yankova, J. V. Rau, A. N. Vorobiev

“…Solid dispersions are bi- or multicomponent systems consisting of an active substance and a carrier (a highly dispersed solid phase of the active substance or molecular-dispersed solid solutions) with a partial formation of complexes of variable compositions with the carrier material.Materials and methods. …”
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The role of left atrio-ventricular coupling index and left atrial ejection fraction in predicting onset of atrial fibrillation and adverse cardiac events in hypertrophic cardiomyop... by Parisi Francesca, La Franca Eluisa, Pistelli Lorenzo, Gentile Giovanni, Bellavia Diego, Nuzzi Vincenzo, Manca Paolo, Massimiliano Mulè, Zito Concetta, Di Bella Gianluca, Scipione Carerj, Cipriani Manlio, Francesco F. Faletra

“…Eleven patients experienced the composite outcome of cardiovascular death or heart transplant, and a LACI > 60% was associated with this outcome. …”
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Designing model of place branding based on brand attachment (Kish Island case study) by khadigeh Ghaemmaghami Tabrizi, Asghar Moshabaki Esfahaniَ, Abdolah Naami, Naser Azad

“…In addition, finding the new variable, research topic (branding with approach of brand attachment on Tourism Island) is another innovation which this study achieved.…”
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Sources of risk communication, knowledge and preventive practices toward Lassa fever in Bauchi State, Nigeria by Benjamin Bukky Ilesanmi, Nathanael Afolabi, Olayinka Badmus, Munkail Titilola, Abdulmajid Ahmad, Usman Inuwa, Matthew Okoh, Hajara Aliyu, Shittu Abdu-Aguye, Foyeke Oyedokun-Adebagbo

“…We analysed data of 1173 respondents aged 18 years and above who have heard of LF. Composite and median statistics were used to compute KPLF and was dichotomized into low and high. …”
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Catalytic hydroprocessing of yellow dodolla oil using thermally stable and mesoporous AlPO4-18 supported β-Mo2C, Ni3C, and WC nanoparticles to produce bio-jet fuel by Zinnabu Tassew Redda, Steffen Kadow, Mirko Barz, Abubeker Yimam, Hartmut Wesenfeld, Daniel Brennecke, Asnakech Laß-Seyoum

“…The characterization results revealed that the hydrocracked liquid products possessed virtually identical physicochemical properties, chemical compositions, hydrogen-to-carbon atomic ratios (1.90–1.92), oxygen-to-carbon atomic ratios (0.002–0.030), and gravimetric energy densities (41.35–42.89 MJ kg−1) to those of conventional jet fuels. …”
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Large-scale epidemiology of opisthorchiasis in 21 provinces in Thailand based on diagnosis by fecal egg examination and urine antigen assay and analysis of risk factors for infecti... by Kulthida Y Kopolrat, Chanika Worasith, Phattharaphon Wongphutorn, Anchalee Techasen, Chatanun Eamudomkarn, Jiraporn Sithithaworn, Watcharin Loilome, Nisana Namwat, Attapol Titapun, Chaiwat Tawarungruang, Bandit Thinkhamrop, Samarn Futrakul, Simon D Taylor-Robinson, Melissa R Haswell, Narong Khuntikeo, Thomas Crellen, Paiboon Sithithaworn

“…When assessed against a composite reference standard (combined ELISA and FECT), the urine ELISA yielded a diagnostic sensitivity of 91.6%, compared with 21.9% for FECT. …”
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Investigating the relationship between sleep disturbances and psychopathology In children and adolescents with microdeletion of 22q11 chromosome: an exploratory study by Maria Rosaria Lala, Domenica Bellantoni, Federica Alice Maria Montanaro, Federica Alice Maria Montanaro, Maria Pontillo, Paolo Alfieri, Stefano Vicari, Stefano Vicari

“…Both groups demonstrated low mean IQ scores and low general adaptive functioning, as measured by the Wechsler Intelligence Scale for Children (WISC-IV) and the ABAS II General Adaptive Composite (GAC), respectively. Furthermore, Group 1 exhibited significantly lower functioning when assessed using the CGAS. …”
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Association of depression in multiple sclerosis with fatigue, sleep disturbances, disability, and health-related quality of life: Outcomes of a cross-sectional study by E. Aparicio-Castro, A. Candeliere-Merlicco, C.M. Santa, R. Villaverde-González

“…They also had significantly higher fatigue and daytime somnolence scores, as well as lower scores on the MSQOL-54: physical (40.55 vs. 62.3; P<.001) and mental (44.49 vs. 71.89; P<.001) health composites. We demonstrated the correlation between depression and fatigue, as well as their negative impact on QoL in patients with MS. …”
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Impact of Financial Literacy on Saving Decisions: Insight from Aseman Project Operated by Barkat Foundation by VAhid Moghadam, Hadi Amiri, Sahar Baharipour, Fatemeh Bagheri, Parisa GHasemian

“…The results showed Cronbach's alpha and composite reliability values above 0.7 for all variables, thus indicating acceptable reliability.To evaluate the impact of Aseman Project, the study examined the effect of microfinance fund membership on the dependent variables of financial knowledge, saving attitude, and saving behavior. …”
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Prediction of slaughter weight with body components and liner body measurement of Hararge cattle at Haramaya University abattoir, Ethiopia by Takele Wolkaro, Yosef Tadesse, Mengistu Urge, Merga Bayisa

“…To achieve wider application of this model, it would be desirable to validate the equation with large population, different breed and age compositions which have been more accurately determined under different management systems.…”
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Clinical characteristics, prognosis, and predictive modeling in class IV ± V lupus nephritis by Anjing Wang, Anjing Wang, Yunlong Qin, Yunlong Qin, Yan Xing, Zixian Yu, Liuyifei Huang, Jinguo Yuan, Yueqing Hui, Mei Han, Guoshuang Xu, Jin Zhao, Shiren Sun

“…ObjectiveThe objective of this study is to compare the clinical features and survival outcomes of class IV ± V lupus nephritis (LN) patients, identify risk factors, and develop an accurate prognostic model.MethodsThis study enrolled patients diagnosed with class IV ± V LN by renal biopsy at Xijing Hospital from December 2013 to June 2023. The composite endpoint of the study was defined as a decline in the estimated glomerular filtration rate (eGFR) by more than 50%, progression to end stage renal disease, or death, whichever came first. …”
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NF1 expression profiling in IDH-wildtype glioblastoma: genomic associations and survival outcomes by Michael Chang, Mohamed Sherief, Maria Ioannou, Viveka Chinnasamy, Lucy Chen, Michael Frost, Michelle Mattson-Hoss, Herb Sarnoff, David O. Kamson, Matthias Holdhoff, Debraj Mukherjee, Chetan Bettegowda, Jordina Rincon-Torroella, Victoria Croog, Peng Huang, Fausto J. Rodriguez, Calixto-Hope G. Lucas, Karisa C. Schreck

“…Here, we seek to perform a composite analysis for NF1 loss accounting for genomic alterations and protein expression via immunohistochemistry. …”
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Matrix Metalloproteinases 7 and 10 Are Prognostic Biomarkers for Systemic Cardiovascular Risk in Individuals with Peripheral Artery Disease by Ben Li, Farah Shaikh, Houssam Younes, Batool Abuhalimeh, Abdelrahman Zamzam, Rawand Abdin, Mohammad Qadura

“…The outcome of interest was a 2-year MACE, defined as a composite of myocardial infarction, stroke, or mortality. …”
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Correlation of plasma insulin-like factor 6 level with risk of acute aortic syndrome and adverse prognosis by DONG Wang, DONG Wang, WANG Ying, ZHANG Mingle

“…Multivariate COX regression analysis revealed that, after adjusting for sex, age, systolic blood pressure, ST classification, and surgical treatment, acute-phase INSL6 level was independently associated with all-cause mortality (HR: 0.999, 95%CI: 0.999~1.000, P=0.023), AAS-related mortality (HR: 0.999, 95%CI: 0.998~1.000, P=0.012), and composite endpoint events (HR: 0.999, 95%CI: 0.999~1.000, P=0.026) in AAS patients during follow-up. …”
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Red cell distribution width-to-platelet ratio (RPR) as a predictor of prolonged stay at hospital for COVID-19 inpatients by Martha Fors, Santiago J. Ballaz

“…Aims/Background We looked at novel hematological composites like the neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, red cell distribution width-to-lymphocyte ratio, red cell distribution width-to-platelet ratio, leukocyte-to-C reactive protein ratio, and lymphocyte-to-C reactive protein ratio as explanatory variables for COVID-19 patients´ hospital length of stay (LoS).Methods The association of hematological indices with LoS was analyzed on 2930 COVID-19 patients using the univariate and multivariable Cox proportional hazards regression models with enter method. …”
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Cardiometabolic Biomarkers and Prediction of Kidney Disease Progression: The eGFR Cohort Study by Elizabeth L. M. Barr, Federica Barzi, Phillip Mills (Kulkalgal), Maria Nickels, Sian Graham, Odette Pearson, Varuni Obeyesekere, Wendy E. Hoy, Graham R. D. Jones, Paul D. Lawton, Alex D. H. Brown, Mark Thomas, Ashim Sinha, Alan Cass, Richard J. MacIsaac, Louise J. Maple-Brown, Jaquelyne T. Hughes (Wagadagam)

“…Annual change in eGFR (ml/min/1.73 m 2 ) and a composite kidney outcome (first of ≥30% eGFR decline with follow-up eGFR <60 ml/min/1.73 m 2 , initiation of kidney replacement therapy or kidney disease-related death) over a median of 3 years. …”
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Tumor mutational burden and survival on immune checkpoint inhibition in >8000 patients across 24 cancer types by Vivek Subbiah, Samuel J Klempner, Neeraj Agarwal, David P Carbone, Amit Mahipal, Shilpa Gupta, David Fabrizio, Jeffrey S Ross, Gerald Li, David R Gandara, Miles C Andrews, Jonathan W Riess, Ramez N Eskander, Ryon P Graf, Geoffrey R Oxnard, Sarah Sammons, Jeremy Snider, Lilia Bouzit, Cheryl Cho-Phan, Megan Price, Julia C F Quintanilha, Richard Sheng Poe Huang

“…This study used the TMB algorithm from the FDA-approved test supporting solid tumor CDx and composite mortality variable validated against the national death index: real-world overall survival (rwOS). …”
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Optimization of synthesis conditions of hydrochar and pyrohydrochar from fish bones for their use in the adsorption of fluoride from water by Sergio Armando Cruz Briano, Nahum Andrés Medellín Castillo, Juan Carlos Moreno Piraján, Liliana Giraldo Gutiérrez, Guillermo Javier Castro Larragoitia, Pablo Delgado Sánchez, Alfredo Israel Flores Rojas, Hilda Guadalupe Cisneros Ontiveros

“…For this purpose, a D-Optimal experimental composite central design was established using response surface methodology (RSM) considering three levels for temperature and synthesis time. …”
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Factors Affecting the Counterproductive Behaviors of Employees in the Organization; Emphasizing the Role of Organizational Embeddedness, Emotional Intelligence and Psychological Ow... by Marziyeh Dehghanizadeh, Mehdi Kheirandish, Hojjat Kheirandish

“…The validity of the questionnaires was confirmed a panel of experts in the field, and Cronbach's alpha coefficient and composite reliability were used to estimate the reliability of the instruments. …”
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Predicting incident type 2 diabetes in a Japanese cohort: an 8-year analysis of the NAGALA database by Yangchun Wang, Fei Liu, Ruixiang Tong, Zhonghua He, Qin Fang, Jie Feng, Hongliang An, Junjun Liu

“…The ability of individual components and a composite risk score to discriminate was assessed using Receiver Operating Characteristic (ROC) curves.ResultsOver an average follow-up duration of 2207.82 ± 1379.73 days, 262 patients (1.7%) had the onset of T2DM. …”
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