Peripherally inserted central catheters versus implanted port catheters in patients with breast cancer: a post hoc analysis of the PICCPORT randomised controlled trial by Anton Utas, Stefanie Seifert, Knut Taxbro

“…The primary endpoint was a composite variable encompassing thrombotic, occlusive, infectious, or mechanical complications, while patient satisfaction served as a secondary endpoint. …”
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Multivariate neural markers of individual differences in thought control difficulties by Jacob DeRosa, Harry R. Smolker, Hyojeong Kim, Boman Groff, Jarrod Lewis-Peacock, Marie T. Banich

“…The current study examined the hypothesis that aspects of these multi-voxel patterns are associated with an individual’s difficulty in controlling thoughts, as derived from a composite of three self-report questionnaires, in a non-clinical (N = 48) sample. …”
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Optimized Design and Test of Geometrically Nonlinear Static Aeroelasticity Model for High-Speed High-Aspect-Ratio Wing by Xing Li, Wei Qian, Ling Xiao, Xinyu Ai, Jun Liu

“…Large transport aircraft tend to adopt a wing layout with a high aspect ratio and swept-back angle due to the requirement of a high lift-to-drag ratio. Composite material is typically employed to ensure the light weight of the structure, causing serious static aeroelasticity problems to the aircraft. …”
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Low hemoglobin, albumin, lymphocyte, and platelet score increases symptomatic intracranial hemorrhage risk in thrombectomy patients by Shuaiyu Chen, Zhihang Huang, Jingwen Qi, Bin Wei, Yan E, Chunmei Liu, Yingdong Zhang, Xiaohao Zhang

“…BackgroundThe HALP index, a composite biomarker integrating hemoglobin, albumin, lymphocyte, and platelet parameters, reflects both immunological competence and nutritional status. …”
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Removal of chromium from synthetic wastewater by electrocoagulation and using natural coagulant (blend of hen eggshell powder with lime): optimization of response surface methodolo... by Werkne Sorsa Muleta, Firomsa Bidira Abdi, Endrias Adane Bekele

“…In this work, the removal of Cr from synthetic wastewater by electrocoagulation supported by natural coagulant (eggshell powder) with aluminum electrodes was investigated. The central composite design of the response surface methodology was employed to estimate and optimize process variables, such as initial Cr concentration (225–475 mg/L), solution pH (5–9), and current density (0.35–045 A/m2), and treatment time (30–40 min) with an electrode distance (ED) of 0.5 and 1 cm, respectively. 99.90% and 99.74% of removal efficiencies were observed at initial Cr concentration of 456.11 mg/L, a solution pH of 5.45, with current density of 0.47 A/m2, and treatment time of 36.84 min. …”
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Predictors of Successful Memory Aging in Older Mexican Adults by Rosa Estela García-Chanes, Luis Miguel Gutiérrez-Robledo, Teresa Álvarez-Cisneros, Paloma Roa-Rojas

“…This is known as successful memory aging and is associated with specific neurophysiological features and psychological and lifestyle-related variables. To date, little is known about the association between successful memory aging and intrinsic capacity (IC) defined as “the composite of all the physical and mental (including psychosocial) capacities that an individual can draw on at any point in time” and resilience. …”
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Application of a novel vegetation condition index using MODIS EVI for structuring crop index insurance under a smallholder system by Andualem Aklilu Tesfaye, Daniel Edward Osgood, Berhane Gessesse Aweke

“…The study took advantage of a 16-day composite of MODIS EVI and a well-archived historical (2007–2022) in-situ data on drought prevalence, which is managed by the R4 crop insurance program, one of the well-established insurance schemes at a global scale. …”
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Design and Optimization of Friction Winch for 25 MW Airborne Wind Energy Systems by Lizhao NIU, Kuo YIN, Chonghui LEI

“…Parameterized modeling of the drum was conducted, followed by sensitivity analysis to screen out structural parameters with significant sensitivity to maximum stress, mean stress and geometric mass. Using the central composite experimental design method, a response surface model was established for the drum's stress, mass and main design structural parameters. …”
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Exploring the concurrent validity of a linguistically responsive pre-reading assessment in bilingual children: the Urdu Phonological Tele-Assessment (U-PASS) tool by Insiya Bhalloo, Insiya Bhalloo, Monika Molnar, Monika Molnar

“…The U-PASS consists of 10 phonological awareness, phonological memory, and rapid automatized naming subtests.MethodsWe tested 115 typically-developing Urdu-English simultaneous bilinguals in Grades 1–2 across Canada and Pakistan on the U-PASS, vocabulary and reading accuracy measures, and background questionnaires.ResultsItem-level analysis, involving point-biserial correlations, accuracy rates, and Cronbach’s alpha, and linear regression, involving subtest- and composite-level analysis, were used to collect evidence for U-PASS’s internal reliability and criterion-based concurrent validity.DiscussionOur linear regression analyses indicated significant phonological processing-reading associations after accounting for background variables, thereby demonstrating U-PASS’s concurrent validity for assessing Urdu word/non-word reading. …”
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Lipidomic risk scores are independent of polygenic risk scores and can predict incidence of diabetes and cardiovascular disease in a large population cohort. by Chris Lauber, Mathias J Gerl, Christian Klose, Filip Ottosson, Olle Melander, Kai Simons

“…The participants in the highest risk group showed significantly altered lipidome compositions affecting 167 and 157 lipid species for T2D and CVD, respectively. …”
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Risk factors for severe outcomes in people with diabetes hospitalised for COVID-19: a cross-sectional database study by Kamlesh Khunti, Pere Domingo, Josep Franch-Nadal, Manel Mata-Cases, Jordi Real, Didac Mauricio, Esmeralda Castelblanco, Emilio Ortega, Rosa Corcoy, Mònica Gratacòs, Francesc Xavier Cos Claramunt, Ramon Puig-Treserra, Bogdan Vlacho

“…Aim This study’s objective was to assess the risk of severe in-hospital complications of patients admitted for COVID-19 and diabetes mellitus (DM).Design This was a cross-sectional study.Settings We used pseudonymised medical record data provided by six general hospitals from the HM Hospitales group in Spain.Outcome measures Multiple logistic regression analyses were used to identify variables associated with mortality and the composite of mortality or invasive mechanical ventilation (IMV) in the overall population, and stratified for the presence or absence of DM. …”
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Impact of life adversity and gene expression on psychiatric symptoms in children and adolescents: findings from the Brazilian high risk cohort study by Vanessa Kiyomi Ota, Vanessa Kiyomi Ota, Vanessa Kiyomi Ota, Vanessa Kiyomi Ota, Adrielle Martins Oliveira, Adrielle Martins Oliveira, Adrielle Martins Oliveira, Amanda Victória Gomes Bugiga, Amanda Victória Gomes Bugiga, Amanda Victória Gomes Bugiga, Helena B. Conceição, Pedro Alexandre Favoretto Galante, Paula Fontes Asprino, Julia Luiza Schäfer, Julia Luiza Schäfer, Mauricio Scopel Hoffmann, Mauricio Scopel Hoffmann, Mauricio Scopel Hoffmann, Mauricio Scopel Hoffmann, Mauricio Scopel Hoffmann, Rodrigo Bressan, Rodrigo Bressan, Rodrigo Bressan, Elisa Brietzke, Gisele Gus Manfro, Gisele Gus Manfro, Rodrigo Grassi-Oliveira, Ary Gadelha, Ary Gadelha, Luis Augusto Rohde, Luis Augusto Rohde, Luis Augusto Rohde, Luis Augusto Rohde, Euripedes Constantino Miguel, Euripedes Constantino Miguel, Pedro Mario Pan, Pedro Mario Pan, Pedro Mario Pan, Marcos Leite Santoro, Marcos Leite Santoro, Marcos Leite Santoro, Giovanni Abrahao Salum, Giovanni Abrahao Salum, Giovanni Abrahao Salum, Carolina Muniz Carvalho, Carolina Muniz Carvalho, Carolina Muniz Carvalho, Sintia Iole Belangero, Sintia Iole Belangero, Sintia Iole Belangero, Sintia Iole Belangero

“…This study investigated the association between the expression of 78 candidate genes, previously associated with psychiatric phenotypes, in peripheral blood and both adversity and psychopathology in a sample of 298 young individuals assessed at two time points from the Brazilian High Risk Cohort Study for Mental Conditions (BHRCS).MethodsPsychopathology was assessed using the Child Behavior Checklist (CBCL), considering the total CBCL, p-factor (i.e. general factor of psychopathology), and internalizing and externalizing symptoms as clinical variables. The life adversities considered in this study includes four composite variables: child maltreatment, stressful life events, threat and deprivation. …”
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Structural Model of Factors Affecting the Use of Organic Fertilizers by Rice Farmers during Rice (Oryza sativa) Cultivation in Dezful County by Zahra Eskanadari, Moslem Saavri, Masoud Yazdanpanah

“…The form and content validity of the questionnaire was confirmed by experts' opinion and its reliability was confirmed through Cronbach's alpha and composite reliabilityResults and DiscussionThe results of the structural equation modeling research showed that the variables of self-efficacy (ƛ=0.257; P=0.000), action guide (ƛ=0.222; P=0.000), perceived intensity (ƛ=0.121; P=0.035) and perceived sensitivity (ƛ= 0.100; P= 0.046) and perceived benefits (ƛ= 0.319; P= 0.000) have a positive and significant effect on the use of organic fertilizers among rice farmers in Dezful County. …”
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Mechanical properties of RC combination columns configured with ECC jacket by Jieyong You, Cunsheng Li, Yushuai Zhu, Yanheng Zhao, Liang Xu, Xiaodong Han, Yuanzhen Ge, Zengcong Niu, Dongbo Wan, Long Liu

“…A novel structure-SRCC configured with Engineered Cementitious Composites (ECC) jacket (ESRCC) is proposed for breaking through this limitation and improving the load-bearing capacity and ductility of SRCC. …”
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Optimal operating conditions of PES/BiFeO3 mixed matrix membrane for treating dye-contaminated wastewater by Shahad K. Jawad, Khalid T. Rashid, Manal Afham Toma, Adnan A. Abdul Razak, Mohammed Ahmed Shehab, Maryam Y. Ghadhban, Munaf Al-lami, Alhafadhi Mahmood, Haidar Hasan Mohammed, Amaal Ajeel Hmood, Mohammed Faleh Abd Al-Ogaili, Saad Alsarayefi

“…A set of experimental runs for the ultrafiltration (UF) setup was constructed utilizing the central composite design of experiment method. This study examined how operating and preparation conditions affected PES/BiFeO3 membrane permeate flux and MB rejection for all membrane samples. …”
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Investigating the effectiveness of an intraoperative decision support guided fluid therapy intervention on postoperative outcome of high-risk patients undergoing high-risk abdomina... by Sean Coeckelenbergh, Amelie Delaporte, Damien Rousseleau, Jacques De Montblanc, Stephanie Roullet, Joanna Ramadan, Bernard Cholley, Alexandre Stibon, Emmanuel Weiss, Maria-Christina Kassab, Sylvain Diop, Elsa Manzi, Marco Pustetto, Guillaume Porta Bonette, Pierre Gregoire Guinot, Philippe Guerci, Domien Vanhonacker, Francois Martin Carrier, Brenton Alexander, Joseph Rinehart, David Boldt, Tristan Grogan, Maxime Cannesson, Jacques Duranteau, Lamiae Grimaldi, Bruno Pereira, Alexandre Joosten

“…The primary outcome is a composite of major complications and death 30 days after surgery that will be analysed as intention-to-treat. …”
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Unlocking Nature’s Potential: Modelling <i>Acacia melanoxylon</i> as a Renewable Resource for Bio-Oil Production through Thermochemical Liquefaction by Sila Ozkan, Henrique Sousa, Diogo Gonçalves, Jaime Puna, Ana Carvalho, João Bordado, Rui Galhano dos Santos, João Gomes

“…Optimized results showed a bio-oil yield of 83.29% and an HHV of 34.31 MJ/kg. A central composite face-centred (CCF) design was applied to the liquefaction reaction optimization. …”
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Optimization of pyrolysis conditions for Catha edulis waste-based biochar production using response surface methodology by Abdi Birhanu, Abrha Mulu Hailu, Zemene Worku, Israel Tessema, Kenatu Angassa, Solomon Tibebu

“…The effect of pyrolysis process variables embracing reaction temperature, reaction time, and particle size on biochar yield and quality was optimized using response surface methodology (RSM) coupled with central composite design (CCD). …”
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Predicting outcomes following open abdominal aortic aneurysm repair using machine learning by Ben Li, Badr Aljabri, Derek Beaton, Leen Al-Omran, Mohamad A. Hussain, Douglas S. Lee, Duminda N. Wijeysundera, Ori D. Rotstein, Charles de Mestral, Muhammad Mamdani, Mohammed Al-Omran

“…Input features included 35 pre-operative demographic/clinical variables. The primary outcome was 30-day major adverse cardiovascular event (MACE; composite of myocardial infarction, stroke, or death). …”
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Integrating Radiomics and Lesion Mapping for Cerebellar Mutism Syndrome Prediction by Xinyi Chai, Wei Yang, Yingjie Cai, Xiaojiao Peng, Xuemeng Qiu, Miao Ling, Ping Yang, Jiashu Chen, Hong Zhang, Wenping Ma, Xin Ni, Ming Ge

“…<b>Objective:</b> To develop and validate a composite model that combines lesion–symptom mapping (LSM), radiomic information, and clinical factors for predicting cerebellar mutism syndrome in pediatric patients suffering from posterior fossa tumors. …”
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