Formulation optimization of furosemide floating-bioadhesive matrix tablets using waste-derived Citrus aurantifolia peel pectin as a polymer by Ebrahim Abdela Siraj, Yohannes Mulualem, Fantahun Molla, Ashagrachew Tewabe Yayehrad, Anteneh Belete

“…Based on preliminary study, pectin and effervescent agent concentration were identified as significant independent variables. Hence, their influence on five response variables (floating duration, bioadhesive strength, swelling index, drug release at 1 h, and drug release rate) were further studied and optimized using central composite design (CCD). …”
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The Impact of Digital Inequities on Oropharyngeal Cancer Disparities in the United States by David J. Fei‐Zhang, Achilles A. Kanaris, Camaren M. Cuenca, Sydney A. Fleishman, Jill N. D'Souza, Anthony M. Sheyn, Daniel C. Chelius, Jeffrey C. Rastatter

“…Variables were categorized as infrastructure‐access (ie, digital‐related variables) or sociodemographic (ie, education, income, and disability status) and weighted‐averaged into a composite score. …”
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The influence of buyer knowledge and economic level on sports product purchasing decisions by Ilham Ilham, Raihan Alfarobi Raihan, Bekir Erhan Orhan, Vlad Adrian Geantă Geantă

“…Measurement reliability and validity were assessed using Cronbach's alpha and Composite Reliability. Hypotheses were tested through linear regression analysis with a significance threshold of p < 0.05. …”
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Optimization of stope dimensions using response surface method coupling a hybrid chaos-genetic algorithm by Ming lan, Hanwen Jia, Ju Ma

“…Since the latter serves as a criterion for evaluating roof strength failure, it is imperative to establish the appropriate range of parameters that ensure the rock mechanics stability during mining operations. Through central composite testing, numerical simulations were conducted to obtain mechanical response characteristics under different stope dimensions. …”
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Core features and inherent diversity of post-acute infection syndromes by Alain Trautmann

“…A useful discrimination between different PAIS subtypes should be obtained with a composite profiling including biomarkers, questionnaires and functional tests so as to take into account PAIS multidimensionality.…”
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Ductility of continuous RC beams strengthened with partially bonded near-surface mounted CFRP bars by Mahmoud A. Abdelraouf, Ayman H. Khalil, Ahmed F. Maree, Amr M. Ibrahim

“…The linear brittle behavior of these composite materials can be an excessive limitation for assuring the required level of ductility and moment redistribution. …”
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Subtelomeric repeat expansion in Hydractinia symbiolongicarpus chromosomes by Tetsuo Kon, Koto Kon-Nanjo, Oleg Simakov

“…Only recently, high quality chromosome-level genome assemblies enabled identification of repeat compositions along a broad range of animal chromosomes. …”
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On the propagation and interaction of the low-frequency ion-acoustic multi-solitons in a magnetoplasma having nonextensive electrons using Hirota bilinear method by Aljawhara H Almuqrin, Delmas V Douanla, Camus GL Tiofack, Alim, Alidou Mohamadou, Sherif ME Ismaeel, Samir A El-Tantawy

“…The reductive perturbation method is utilized to obtain the Korteweg-de Vries (KdV) equation for describing the low-frequency IAWs in proximity to critical values of the pertinent physical variables in the system. At specific essential plasma compositions, the modified KdV (mKdV) equation is derived for the parameter values at which the KdV model fails to analyze the nonlinear dynamics of the low-frequency IAWs adequately. …”
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Response Surface Optimization of Cactus Pear (Opuntia ficus-indica) with Lantana camara (L. camara) Fruit Fermentation Process for Quality Wine Production by Zenebe Tadesse Tsegay, Solomon Mengistu Lemma

“…Wine quality responses were optimized at an experimental strategy developed using central composite rotatory design by varying fermentation process variable temperature, inoculum, and Lantana camara fruit juice concentration for six days. …”
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Wastewater Treatment Using a Photoelectrochemical Oxidation Process for the Coffee Processing Industry Optimization of Chemical Oxygen Demand (COD) Removal Using Response Surface M... by Firomsa Bidira Abdi, Zerihun Asmelash Samuel, Seifu Kebede Debela, Temesgen Abeto Amibo

“…The response surface methodology (RSM) based on central composite design (CCD) was used to organize the trial runs and optimize the results. …”
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The Jurisprudential Study of the Nature of the Postpaid Landline Phone Subscription Contract by Muhammad Ghanbarzadeh, Ali Akbar Izadifard, Saeed Ebrahimi

“…Based on this with analyzing the purport of this contract, it has been challenged the way of the relationship between the subscriber and telecommunication and customizing the telecommunication equipment (instruments) to it and how calculating the expenses relating to this contract, the opinions which think that the subscription agreement is inclusively leasing (Arabic:اجاره ijarah) and sale (Arabic: بیع bay') contract and it is accepted the opinion of the composite (compound) contract for determining the nature of this contract. …”
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Lean manufacturing implementation in food and beverage SMEs in Tanzania: using structural equation modelling (SEM) by Juma M. Matindana, Mary J. Shoshiwa

“…Using Exploratory Factor Analysis (EFA) and Confirmatory Composite Analysis (CCA), data from 113 SMEs were analysed, revealing that lean tools and processes are strong predictors of improved output, with a significant portion of variance explained by the model. …”
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Identifying and validating the dimensions and components of improving the medical education system in the implementation of online curricula by Gita Zandieh, Aladdin Etemad Ahri, Zolfaghar Rashidi

“…The validity of the questionnaire was obtained from factor analysis and reliability from the index of Cronbach's alpha coefficient and composite reliability. The questionnaire was distributed among 380 professors of different disciplines. …”
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Hybrid Gaussian Process Regression Models for Accurate Prediction of Carbonation-Induced Steel Corrosion in Cementitious Mortars by Teerapun Saeheaw

“…Four Gaussian Process Regression (GPR) variants were systematically developed: Baseline GPR with manual optimization, Expert Knowledge GPR employing domain-driven dual-kernel architecture, GPR with Automatic Relevance Determination (GPR-ARD) for feature selection, and GPR-OptCorrosion featuring specialized multi-component composite kernels. The models were trained and validated using 180 carbonated mortar specimens with 15 systematically categorized variables spanning mixture, material, environmental, and electrochemical parameters. …”
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Production, Optimization and Characterization of L-asparaginase from Endophytic Fusarium oxysporum Strain MJS2, an Isolate of Mirabilis jalapa by Sani Sen, Hiran Kanti Santra, Debdulal Banerjee

“…The fermentation conditions were optimized through One Variable At a Time (OVAT) joined with a Central Composite Design (CCD) for the maximum production of enzymes. …”
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Drivers of coral reef marine protected area performance. by Venetia Alexa Hargreaves-Allen, Susana Mourato, Eleanor Jane Milner-Gulland

“…Although certain performance measures were correlated, most were not, suggesting trade-offs that limit the usefulness of composite performance scores. Hypotheses were generated as to the impact of MPA features, aims, location, management and contextual variables on MPA performance from the literature. …”
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Ranking of Iranian metropolises based on urban smartness index by Somayeh Ghiasy, Sohrab Delangizan, Mohammad sharif Karimi

“…This study aims to assess the level of smartness in Iranian metropolises and introduce a composite index for measuring smartness and then ranking and clustering them. …”
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Investigation of Structural Relationships of Factors Affecting Posttraumatic Growth in Women With Breast Cancer by Azam Hashemian Moghadam, Hamid Reza Aghamohammadian Sharbaf, Mohammad Saeid AbdeKhodaei, Hossein Kareshki, Mona Joudi

“…In the measurement model section, three convergent validity indices, i.e., Average Variance Extracted (AVE), Composite Reliability (CR), and the Cronbach α, and in the structural model section, two indicators of coefficient of determination (R2) and Stone-Geisser coefficient (Q²).  …”
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Study on the influence of CO2-water-rock reactions under reservoir conditions on geochemical properties of sandstone reservoirs by ZHANG Chao, ZHU Pengyu, HUANG Tianjing, YAN Changhao, LIU Jie, WANG Bo, ZHANG Bin, ZHANG Yi

“…Advanced equipment, including high-performance field-emission scanning electron microscope and X-ray diffraction, was utilized to study the effects and mechanisms of CO2-water-rock reactions on reservoir physical properties and mineral compositions under different environmental variables. …”
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High-dimensional mediation analysis reveals the mediating role of physical activity patterns in genetic pathways leading to AD-like brain atrophy by Hanxiang Xu, Shizhuo Mu, Jingxuan Bao, Christos Davatzikos, Haochang Shou, Li Shen

“…Specifically, we used a composite imaging marker, Spatial Pattern of Abnormality for Recognition of Early AD (SPARE-AD) that characterizes AD-like brain atrophy, as an outcome variable to represent AD risk. …”
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