Long-term prognosis after acute coronary syndrome due to de novo coronary artery lesions and stent thrombosis in patients on hemodialysis by Sho Nakao, Takayuki Ishihara, Katsuki Okada, Hirota Kida, Takuya Tsujimura, Shota Okuno, Toshiaki Mano, Atsushi Kikuchi, Takashi Morita, Ryu Shutta, Masami Nishino, Shumpei Kosugi, Yasunori Ueda, Yasuhiro Ichibori, Yoshiharu Higuchi, Daisuke Nakamura, Daisaku Nakatani, Shungo Hikoso, Yohei Sotomi, Yasushi Sakata

“…The primary outcome was the 6-year incidence of major adverse cardiac events (MACE) defined as a composite of cardiac death, non-fatal myocardial infarction, target vessel revascularization, and subsequent ST. …”
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Annual cycle variations in the gut microbiota of migratory black-necked cranes by Yujia Zhang, Ruifeng Ma, Suolangduoerji, Shujuan Ma, Shujuan Ma, Akebota Nuertai, Ke He, Hongyi Liu, Ying Zhu

“…However, the annual dynamics of gut microbiota in migratory birds remain unclear, hindering our understanding of their environmental adaptation.MethodsHere, we collected fecal samples from black-necked cranes (Grus nigricollis) across four seasons at their breeding grounds and used wintering ground data from databases to characterize their gut microbial compositions throughout the year.Results and discussionThe results showed that the gut microbiota was clustered by season (Bray-Curtis: R2 = 0.348, p < 0.001; UniFrac: R2 = 0.352, p < 0.001). …”
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Association between triglyceride-glucose related indices and at-risk NASH in U.S. adults with NAFLD: results from NHANES 2017-2020 by Hanchen Ma, Wenjie Zhang, Wenjie Zhang, Zheng Zhao, Shuaichen Jin, Linchuan Li, Linchuan Li, Ruizhao Zong, Ruizhao Zong, Wuyang Li, Wuyang Li, Ziwei Zhang, Ziwei Zhang, Shichang Cui, Shichang Cui, Yunmiao Pan, Jiankang Zhu, Jiankang Zhu, Guangyong Zhang, Guangyong Zhang, Guangyong Zhang

“…TyG-WtHR exhibited the strongest association both as a continuous variable and across tertiles in Model 3, demonstrating a near-linear dose-response relationship. RCS analysis revealed no significant nonlinear relationships in composite indices, whereas the TyG index demonstrated a significant nonlinear association. …”
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Impact of short-term aircraft noise on cardiovascular disease risk in the area surrounding London Heathrow airport: the RISTANCO epidemiological study by Xiangpu Gong, Nicole Itzkowitz, Calvin Jephcote, Kathryn Adams, Glory O Atilola, John Gulliver, Marta Blangiardo, Anna Hansell

“…Objectives were: to obtain daily estimates of day and night-time noise average exposure and number of noisy (flight) events for 2014–18 for the population living around London Heathrow airport; to link the noise estimates to cardiovascular hospital admission and mortality data via postcode of residence; to conduct a case-crossover analysis relating daily changes in aircraft noise to cardiovascular disease morbidity and mortality, taking account of relevant confounders that also change on a day-to-day basis such as temperature and air pollution; to identify relevant interactions for areas with consistent patterns of noise exposure versus those with changing patterns of noise exposure and to explore interactions with age, gender, ethnicity and deprivation. …”
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Deep Learning-Based Identification of Echocardiographic Abnormalities From Electrocardiograms by Goro Fujiki, MD, Satoshi Kodera, MD, PhD, Naoto Setoguchi, MD, Kengo Tanabe, MD, PhD, Kotaro Miyaji, MD, PhD, Shunichi Kushida, MD, PhD, Mike Saji, MD, PhD, Mamoru Nanasato, MD, PhD, Hisataka Maki, MD, PhD, Hideo Fujita, MD, PhD, Nahoko Kato, MD, PhD, Hiroyuki Watanabe, MD, PhD, Minami Suzuki, MD, Masao Takahashi, MD, PhD, Naoko Sawada, MD, PhD, Jiro Ando, MD, Masataka Sato, MD, Shinnosuke Sawano, MD, PhD, Susumu Katsushika, MD, PhD, Hiroki Shinohara, MD, PhD, Norifumi Takeda, MD, PhD, Katsuhito Fujiu, MD, PhD, Hiroshi Akazawa, MD, PhD, Hiroyuki Morita, MD, PhD, Issei Komuro, MD, PhD

“…Conclusions: We have developed convolutional neural network models that predict a wide range of echocardiographic findings, including left-sided cardiac abnormalities, valvular heart diseases, and right-sided cardiac abnormalities from ECGs and created a model to predict a composite findings label by logistic regression analysis. …”
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Valuing health-related quality of life among the Indian population: a protocol for the Development of an EQ-5D Value set for India using an Extended design (DEVINE) Study by Atul Sharma, Manmeet Kaur, Shankar Prinja, Gaurav Jyani, Sitanshu Sekhar Kar, Mayur Trivedi, Binod Patro, Fredrick Purba, Star Pala, Swati Raman, Shalu Jain

“…The TTO valuation will be done using 10 composite TTO (c-TTO) tasks and 7 discrete choice experiment (DCE) tasks. …”
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Characteristics and indication of hydrocarbon-generating organisms in sub-salt Majiagou Formation of well T112, central and eastern Ordos Basin by Yinuo ZHANG, Dongdong ZHANG, Liubin WEI, Wenhui LIU, Pingping SHI, Xiaofeng WANG, Qian ZHANG, Yining LI, Zhicheng JIN

“…The fifth member (Ma 5 member) contained more planktonic algae, the fourth member (Ma 4 member) was dominated by benthic algae, and the third member (Ma 3 member) predominantly contained mineral bituminous groundmass. Geochemical data indicated higher total organic carbon (TOC) content in the Ma 3 and Ma 5 members, with minimal variations in organic carbon isotope compositions. …”
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Association of habitual glucosamine use with risk of microvascular complications among individuals with type 2 diabetes: a prospective cohort study in UK biobank by Zi-Jian Cheng, Yu-feng Luo, Qing-yun Zhu, Yan-fei Wang, Wen-yan Ren, Fei-yan Deng, Lin Bo, Xi-Yuan Jiang, Shu-feng Lei, Long-Fei Wu

“…Glucosamine use was significantly associated with lower risks of composite microvascular complications (hazard ratio (HR) 0.89, 95% CI: 0.81 to 0.97) and diabetic nephropathy (HR 0.87, 95% CI: 0.76 to 0.98) in fully adjusted models. …”
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Longitudinal Lipid Trajectories and Progression of CKD in Children by Uwe Querfeld, Marietta Kirchner, Francesca Mencarelli, Karolis Azukaitis, Aysun Bayazit, Ali Duzova, Anke Doyon, Nur Canpolat, Ipek Kaplan Bulut, Lukasz Obrycki, Justine Bacchetta, Rukshana Shroff, Dusan Paripovic, Cengiz Candan, Jerome Harambat, Alev Yilmaz, Harika Alpay, Jun Oh, Hakan Erdogan, Claus P. Schmitt, Anette Melk, Franz Schaefer

“…During a median of 5.1 years of follow-up, 59% of patients reached the composite end point. Kidney survival was significantly different for HDL-C (P = 0.0128), but not for other lipid trajectories in the Kaplan-Meier analysis. …”
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Effects on childhood infections of promoting safe and hygienic complementary-food handling practices through a community-based programme: A cluster randomised controlled trial in a... by Semira Manaseki-Holland, Buba Manjang, Karla Hemming, James T Martin, Christopher Bradley, Louise Jackson, Makie Taal, Om Prasad Gautam, Francesca Crowe, Bakary Sanneh, Jeroen Ensink, Tim Stokes, Tim Stokes, Sandy Cairncross

“…The primary outcome was a composite outcome of the number of times key complementary-food behaviours were observed as a proportion of the number of opportunities to perform the behaviours during the observation period at 6 months. …”
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Clinical Outcomes in Diabetic Females Presenting with STEMI: A Cohort Study by Anjana Ajith Beena, Priya Shanmukhan, Veena Felix, Alummoottil George Koshy, Kunjukrishnapilla Sivaprasad

“…Primary angioplasty was performed in 77%, while thrombolysis was done in 16.7%. The composite outcome was observed in 26.3% of the patients, with heart failure occurring in 19%, cardiogenic shock in 27.9% and death in 16.2%. …”
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Full-Blood Inflammatory Ratios Predict Length of Stay but Not Early Death in Romanian Pulmonary Tuberculosis by Ionut-Valentin Stanciu, Ariadna-Petronela Fildan, Barkha Rani Thakur, Adrian Cosmin Ilie, Livia Stanga, Cristian Oancea, Emanuela Tudorache, Felix Bratosin, Ovidiu Rosca, Iulia Bogdan, Anca Chisoi, Ionela Preotesoiu, Viorica Zamfir, Elena Dantes

“…In this retrospective case–control analysis, we explored whether composite indices derived from routine haematology—namely the neutrophil-to-lymphocyte ratio (NLR), the platelet-to-lymphocyte ratio (PLR), the systemic immune–inflammation index (SII) and a novel CRP–Fibrinogen Index (CFI)—could enhance risk stratification beyond established cytokine measurements among Romanian adults with culture-confirmed pulmonary T. …”
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Impact of HbA1c variability and time‐in‐range fluctuations on large and small nerve fiber dysfunction in well‐controlled type 2 diabetes: A prospective cohort observational study... by Yun‐Ru Lai, Wen‐Chan Chiu, Ben‐Chung Cheng, I‐Hsun Yu, Ting‐Yin Lin, Hui‐Ching Chiang, Chun‐En Aurea Kuo, Cheng‐Hsien Lu

“…At baseline, high HbA1c ARV and TIR ARV groups exhibited higher TCNS and composite nerve conduction amplitude scores but lower cold detection thresholds compared to the low median groups. …”
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Synthesis and Characterization of Hydroxyapatite Assisted by Microwave-Ultrasound from Eggshells for Use as a Carrier of Forchlorfenuron and In Silico and In Vitro Evaluation by Benjamín I. Romero-De La Rosa, Silvia P. Paredes-Carrera, Jorge A. Mendoza-Pérez, Dulce E. Nicolás-Álvarez, Vicente Garibay-Febles, Carlos A. Camacho-Olguin

“…This sample was subsequently used as a carrier for the plant hormone forchlorfenuron (FCF), forming the composite Hap-FCF. Comprehensive characterization was conducted using X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), specific surface area analysis (BET method), zeta potential (ZP), scanning electron microscopy (SEM), and bright-field transmission electron microscopy (BFTEM), ensuring reliable and robust data. …”
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Optimal Medical Therapy for Heart Failure and Integrated Care in Patients With Atrial Fibrillation: A Report From the ESC‐EHRA EORP Atrial Fibrillation Long‐Term General Registry... by Niccolò Bonini, Marco Proietti, Giulio Francesco Romiti, Marco Vitolo, Ameenathul Mazaya Fawzy, Wern Yew Ding, Jacopo Francesco Imberti, Laurent Fauchier, Francisco Marin, Michael Nabauer, Gheorghe Andrei Dan, Tatjana S. Potpara, Giuseppe Boriani, Gregory Y. H. Lip

“…The primary end point was the composite of all‐cause death and major adverse cardiovascular events. …”
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Soil properties under different land uses and slope gradients: Implications for sustainable land management in the Tach Karnuary watershed, Northwestern Ethiopia by Tenagne Ewunetu, Tenagne Ewunetu, Yihenew G. Selassie, Yihenew G. Selassie, Eyayu Molla, Habtamu Admase, Ashenafei Gezahegn, Ashenafei Gezahegn

“…Standard laboratory procedures were employed to analyze the physical properties (bulk density, porosity, and texture) and chemical properties (pH, organic matter, total nitrogen, available phosphorus, cation exchange capacity, and exchangeable cations). Data were statistically analyzed using analysis of variance (ANOVA).Results:The ANOVA results revealed that land-use type significantly (p < 0.05) affected most soil physicochemical properties, including texture, bulk density, porosity, pH, available phosphorus, organic matter, total nitrogen, cation exchange capacity, and exchangeable cations. …”
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Clinical effectiveness of oral antiviral treatment for non-hospitalized high-risk patients with COVID-19 during Omicron JN.1 subvariant wave: a US-based propensity-matched cohort s... by Wan-Hsuan Hsu, Bo-Wen Shiau, Po-Yu Huang, Ya-Wen Tsai, Jheng-Yan Wu, Ting-Hui Liu, Min-Hsiang Chuang, Shu-Farn Tey, Lun-Wu Hung, Chih-Cheng Lai

“…Abstract Background This real-world study aimed to assess the effectiveness of novel oral antiviral agents in managing COVID-19 among high-risk patients during the Omicron JN.1 subvariant wave. Methods Data from the TriNetX US network were analyzed using a multi-institutional propensity score matching (PSM) analysis. …”
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Assessment of mealtime behaviors in Chinese children with autism spectrum disorder by Lili Zhang, Yunjian Zhang, Zhongbi Peng, Yun Chen, Lan Zhang, Lidan Liang, Yi Wang, Hao Zhou

“…The confirmatory factor analysis result shows that BAMBI 18 items have an acceptable fit to the data (GFI = 0.901, CFI = 0.819, ILI = 0.821, RMSEA = 0.074). …”
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Implication of Exclusive Breastfeeding in Early Childhood Dental Disorders: Large Cohort Evidence, US National Survey of Children Health by Laurens Holmes, Janille Williams, Neyha Thompson, Valescia John, Kerti Depeika, Benjamin Ogundele, Michael Enwere

“…This was assessed through a single composite question in the survey, asking parents/guardians if their child had experienced any of these specific oral health issues within the previous year with a binary (yes/no) response option. …”
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Exploring the relationship between social-emotional risk and literacy outcomes: evidence from a collective impact, targeted mentoring initiative by Kimberly Wilson, Nigel Soria, William Polite

“…Design/methodology/approach – The study analyzed data from 396 mentees in grades K-6 using the Social, Academic and Emotional Behavior Risk Screener (SAEBRS) and FastBridge ELA benchmark assessments. …”
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