Antithrombotic agents and effect on outcomes in ischemic stroke with atrial fibrillation and large artery atherosclerosis: a real-world study by Jilu Chen, Jianhua Cheng, Qiang Ye, Yuntao Liu, Yanlei Zhang, Zheng Zhang

“…However, there was no significant difference in one-year recurrent stroke events or risk for bleeding between the APT and OAC groups. Further analysis of the relationship between the dose of OAC and outcome revealed no significant difference between reduced and standard doses of OAC.ConclusionThis study demonstrated that OAC monotherapy was associated with a lower risk for composite outcomes and death after ischemic stroke due to AF and atherosclerotic stenosis, although the OAC dose had no effect on clinical outcomes.…”
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Novel Calcium Phosphate Cement with Metformin-Loaded Chitosan for Odontogenic Differentiation of Human Dental Pulp Cells by Wei Qin, Jia-Yao Chen, Jia Guo, Tao Ma, Michael D. Weir, Dong Guo, Yan Shu, Zheng-Mei Lin, Abraham Schneider, Hockin H. K. Xu

“…Our data further revealed that the novel CPC-chitosan-metformin composite enhanced the odontogenic differentiation of DPCs, as evidenced by higher ALP activity, elevated expression of odontoblastic markers, and strong mineral deposition. …”
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Impact of Baseline Kidney Function on the Rate of Progressive Kidney Disease After Pregnancy: A Population-Based Cohort Study Research Protocol by Lavanya Bathini, Nivethika Jeyakumar, Jessica Sontrop, Eric McArthur, Yuguang Kang, Bin Luo, Aminu Bello, David Collister, Sofia Ahmed, Padma Kaul, Erik Youngson, Branko Braam, Nir Melamed, Michelle Hladunewich, Amit X. Garg

“…Results: Based on a feasibility analysis using ICES data in Ontario, we expect the cohort to include over 400 000 pregnant females and 1.2 million non-pregnant females. …”
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Maternal Clostridium butyricum supplementation during late gestation and lactation enhances gut bacterial communities, milk quality, and reduces piglet diarrhea by Morakot Nuntapaitoon, Piraya Chatthanathon, Matanee Palasuk, Alisa Wilantho, Jakavat Ruampatana, Sissades Tongsima, Sarn Settachaimongkon, Naraporn Somboonna

“…Fecal samples from sows classified as before (Cb=17) and after (Ca=17) probiotic supplementation were analyzed using 16S rRNA gene sequencing and 16S rRNA qPCR, following bioinformatic analyses for alpha-beta diversity, quantitative microbiota, LEfSe (Linear discriminant analysis Effect Size) taxon biomarker analysis, potential microbial metabolism profiles, and statistical correlations with microbial species and clinical data performances. …”
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The role of left atrio-ventricular coupling index and left atrial ejection fraction in predicting onset of atrial fibrillation and adverse cardiac events in hypertrophic cardiomyop... by Parisi Francesca, La Franca Eluisa, Pistelli Lorenzo, Gentile Giovanni, Bellavia Diego, Nuzzi Vincenzo, Manca Paolo, Massimiliano Mulè, Zito Concetta, Di Bella Gianluca, Scipione Carerj, Cipriani Manlio, Francesco F. Faletra

“…Methods Clinical and imaging data from 141 patients with HCM and without a history of AF were retrospectively analyzed over a 5-year period. …”
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Behavior of A Long-lived Borneo Vortex During March 2023 by Syifa Alifia Azzahra, Erma Yulihastin, Alya Fitri Syalsabilla, Eka Putri Wulandari, Maldiva Hafiza Anjarika Suhendar, Jamrud Aminuddin, Acep Purqon

“…The event was classified into three phases: pre-BV (February 25–March 1), during-BV (March 2–10), and post-BV (March 11–15), using a composite analysis approach. Results show enhanced convective activity and widespread precipitation over western Kalimantan and western Java during the pre-BV phase, associated with low-level convergence and warm sea surface temperatures (~28 °C) in the central SCS. …”
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Prediction of Propellant Electrostatic Sensitivity Based on Small-Sample Machine Learning Models by Fei Wang, Kai Cui, Jinxiang Liu, Wenhai He, Qiuyu Zhang, Weihai Zhang, Tianshuai Wang

“…Hydroxyl-terminated-polybutadiene (HTPB)-based composite solid propellants are extensively used in aerospace and defense applications due to their high energy density, thermal stability, and processability. …”
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Acoustic Emission-Based Method for IFSS Characterization in Single-Fiber Fragmentation Tests by Felipe Romero, Franco Méndez, Javiera González, Víctor Tuninetti, Carlos Medina, Meylí Valin, José Valin, Alexis Salas, Cristián Vicuña

“…Carbon fiber-reinforced polymers (CFRP) are widely used composite materials in structural applications, where their mechanical performance is significantly influenced by interfacial shear strength (IFSS). …”
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Exploring the Role of Fibrin Gels in Enhancing Cell Migration for Vasculature Formation by Joana A. Moura, Hugh J. Barlow, Shareen H. Doak, Karl Hawkins, Iris Muller, Martin J. D. Clift

“…Various conditions affecting fibrin gel polymerization, such as different concentrations of fibrinogen and thrombin, were evaluated alongside rheology, porosity, and fiber thickness analysis to understand how these factors influenced cell behavior within the composite biomaterial. …”
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Optimization of biodiesel production from refined cotton seed oil and its characterization by Dominic Okechukwu Onukwuli, Lovet Nwanneka Emembolu, Callistus Nonso Ude, Sandra Ogechukwu Aliozo, Mathew Chukwudi Menkiti

“…These process parameters were optimized using response surface methodology (RSM) and analysis of variance (ANOVA). The significance of the different process parameters and their combined effects on the transesterification efficiency were established through a full factorial central composite design. …”
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The association of HDL-cholesterol levels with incident major adverse cardiovascular events and mortality in 0.6 million individuals with type 2 diabetes: a population-based retros... by David Tak Wai Lui, Lanlan Li, Xiaodong Liu, Xi Xiong, Eric Ho Man Tang, Chi Ho Lee, Yu Cho Woo, Brian Hung Hin Lang, Carlos King Ho Wong, Kathryn Choon Beng Tan

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Inflammation-based scores predict chronic kidney disease progression in patients with chronic kidney disease and chronic heart failure by Lu Cai, Licong Su, Ying Hu, Endi Cai, Hong Xu, Bicheng Liu, Jianping Weng, Chunbo Chen, Huafeng Liu, Qiongqiong Yang, Hua Li, Yaozhong Kong, Guisen Li, Qijun Wan, Yan Zha, Gang Xu, Yongjun Shi, Yilun Zhou, Guobin Su, Ying Tang, Mengchun Gong

“…Glasgow Prognostic Score (GPS), modified Glasgow Prognostic Score (mGPS), Prognostic Nutritional Index (PNI) and Prognostic Index (PI), were used to explore its relationship with CKD progression in patients with CKD stage 1-3b and CHF from the China Renal Data System (CRDS). The composite end point of this study was CKD progression which was defined as eGFR reduction of 40% or progression to end stage renal disease (ESRD).Results Of 8491 patients were enrolled. …”
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Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY): An Observational Cohort Study by Alba Casellas, Cristina Martínez, Judit Amigó, Roser Ferrer, Laia Martí, Carme Merced, Maria Carmen Medina, Istria Molinero, Marta Calveiro, Anna Maroto, Ester del Barco, Elena Carreras, Maria Goya

“…The OR adjusted for this outcome was 1.24 (95% CI: 0.51–3.09). An adjusted analysis showed no differences in the composite adverse outcomes for pregnancy complications (OR: 1.57; 95% CI: 0.84–2.98), delivery complications (OR: 1.21; 95% CI: 0.63–2.35), and neonatal complications (OR: 1.35; 95% CI: 0.61–3.04). …”
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Impact of left atrial strain on clinical outcomes in patients with permanent pacemaker implantation by Goro Yoshioka, Takanori Yamaguchi, Atsushi Tanaka, Hikari Sakai, Junji Koyamatsu, Toshiharu Umeki, Kohei Kaneta, Yoshiko Sakamoto, Atsushi Kawaguchi, Koichi Node

“…In multivariate Cox proportional risk analysis, LASr was independently associated with the primary composite endpoint (hazard ratio, 1.08 per 1% decrease; 95% confidence interval, 1.02–1.15; P = 0.007). …”
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How do patients access and experience long-term care after stroke in the German healthcare system? A qualitative interview study by Christoph Heintze, Christine Holmberg, Sofia Banzhoff, Susanne Döpfmer

“…Objective Understanding how patients access and experience long-term care after stroke, including the kind of medical support desired, in a qualitative interview study; analysis with a question-focused approach adapted from grounded theory methodology.Setting Recruitment in primary care and physical therapy practices in the metropolitan area of Berlin, Germany.Participants 15 patients treated in general practice or physical therapy, whose last stroke occurred more than 2 years ago.Results ‘Shaping relationships’ was the core category extracted from the data as a necessary component to receive appropriate long-term care after stroke. …”
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Clinical impact of inappropriate DOAC dosing in atrial fibrillation: Insights from a real-world registry by Mustafa Yildirim, Hauke Hund, Matthias Mueller-Hennessen, Hugo A Katus, Norbert Frey, Evangelos Giannitsis, Christian Salbach

“…Over-dosage had no significant effect on the HR for the composite endpoint, all-cause mortality, stroke, MI, or major bleeding compared to correct dosing but was associated with higher risks of the composite endpoint (HR 1.43, 95 %CI:1.04–1.96, p = 0.029) relative to under-dosage. …”
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Carbon additives to improve polymer performance in energy applications using machine learning by Juan Chen, Khidhair Jasim Mohammed, Elimam Ali, Riadh Marzouki

“…The model was also used to simulate untested CF–voltage configurations, identifying optimal engineering windows (e.g., 4.5 mm CF at 11 V) that balanced high heating efficiency with manageable power consumption. The integration of data-driven modeling with experimental validation enabled the accurate prediction and strategic tuning of composite properties. …”
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Mode of delivery and outcomes among inborn extremely preterm singletons: A cohort study by Colm P. Travers, Dhuly Chowdhury, Abhik Das, Namasivayam Ambalavanan, Myriam Peralta‐Carcelen, Nancy Newman, Shirley Cosby, Myra Wyckoff, Alan Tita, Waldemar A. Carlo, For the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network

“…Death or severe neurodevelopmental impairment (Bayley Scales of Infant Development‐3rd edition cognitive composite score<70, cerebral palsy (Gross Motor Function Classification Scale >3), bilateral blindness, or bilateral hearing loss) at 18–26 month follow‐up were compared by mode of delivery (cesarean, vaginal including vertex or breech) using propensity score analysis to adjust for baseline characteristics. …”
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The SlDLK2 receptor, involved in the control of arbuscular mycorrhizal symbiosis, regulates hormonal balance in roots by Martín Ramos-Alvelo, Nuria Molinero-Rosales, María Isabel Tamayo-Navarrete, Sanja Ćavar Zeljković, Sanja Ćavar Zeljković, Petr Tarkowski, Petr Tarkowski, José Manuel García-Garrido, Tania Ho-Plágaro

“…We explored the possible role of SlDLK2 on the regulation of hormonal balance. RNA-seq analysis was performed on roots from composite tomato plants overexpressing SlDLK2 and in control plants transformed with the empty vector. …”
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The relationship between job stress and the perception of patient safety culture among Palestinian hospital nurses by Loai M. Zabin, Jamal Qaddumi, Sajed Faisal Ghawadra

“…The study utilized self-report surveys, including the Hospital Survey of Patient Safety Culture (HSOPSC) and the Nursing Stress Scale (NSS), administered to 355 nurses working in 16 North West Bank hospitals in Palestine. The data collected were analyzed via descriptive and inferential analysis. …”
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