Four 2×2 factorial trials of smartphone CBT to reduce subthreshold depression and to prevent new depressive episodes among adults in the community–RESiLIENT trial (Resilience Enhan... by Toshi A Furukawa, Pim Cuijpers, Tatsuo Akechi, Masaru Horikoshi, Yan Luo, Hisashi Noma, Takeo Nakayama, Helen Christensen, Naoki Kondo, Norito Kawakami, Aran Tajika, Ronald C Kessler, Shingo Fukuma, Masatsugu Sakata, Rie Toyomoto, James M S Wason

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The temporal onset of associations of cortical proteins with cognitive resilience vary during late life by Andrea R. Zammit, Tianhao Wang, Lei Yu, Shahram Oveisgharan, Vladislav A. Petyuk, Philip L. De Jager, Julie A. Schneider, David A. Bennett, Aron S. Buchman

“…Cognition was assessed using a composite derived from 19 tests. We first used linear mixed-effects models to identify cortical proteins associated with cognitive resilience. …”
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The Diagnostic and Prognostic Value of the 12-Lead ECG in Arrhythmogenic Left Ventricular Cardiomyopathy by Leonardo Calò, MD, Cinzia Crescenzi, MD, Andrea Di Marco, MD, PhD, Francesca Fanisio, MD, Fabiana Romeo, MD, Alessio Gargaro, MSc, Annamaria Martino, MD, PhD, Chiara Cappelletto, MD, Marco Merlo, MD, Mattia Targetti, MD, Elisabetta Toso, MD, Federica Toto, MD, Maria Beatrice Musumeci, MD, Giacomo Tini, MD, Michele Ciabatti, MD, Matteo Stefanini, MD, Stefano Canestrelli, MD, Elisa Fedele, MD, Chiara Lanzillo, MD, PhD, Armando Fusco, MD, PhD, Federica Carla Sangiuolo, MD, PhD, Cinzia Radesich, MD, Maria Perotto, MD, Maurizio Pieroni, MD, Ruggiero Mango, MD, PhD, Alessio Gasperetti, MD, PhD, Camillo Autore, MD, Michela Casella, MD, PhD, Antonio Dello Russo, MD, PhD, Davide Stolfo, MD, PhD, Mikael Laredo, MD, PhD, Estelle Gandjbakhch, MD, PhD, Maddalena Graziosi, MD, PhD, Elena Biagini, MD, PhD, Costantina Catalano, MD, Ludovica Barile, MD, Fabrizio Drago, MD, Marianna Cicenia, MD, Anwar Baban, MD, PhD, Gemma Pelargonio, MD, PhD, Maria Lucia Narducci, MD, Federica Re, MD, Giovanni Peretto, MD, Elena Paiotti, MD, Carles Diez Lopez, MD, Iacopo Olivotto, MD, Fiorenzo Gaita, MD, Gianfranco Sinagra, MD, Giuseppe Novelli, MD, PhD

“…Objectives: The authors aimed to analyze the electrocardiogram (ECG) characteristics of ALVC, to correlate ECG with cardiac magnetic resonance and genetic data, and to evaluate its prognostic value. Methods: We reviewed data of 125 consecutive patients with ALVC (81.5% desmoplakin pathogenic/likely pathogenic variants). …”
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The association of ideal cardiovascular health and its change with subclinical atherosclerosis according to glucose status: A prospective cohort study by Xiaojing Jia, Yilan Ding, Chunyan Hu, Hong Lin, Lin Lin, Xueyan Wu, Hongyan Qi, Shuangyuan Wang, Ruizhi Zheng, Jie Zheng, Min Xu, Yu Xu, Tiange Wang, Zhiyun Zhao, Yuhong Chen, Mian Li, Guang Ning, Weiqing Wang, Weiguo Hu, Yufang Bi, Jieli Lu

“…The multivariable‐adjusted odds ratio (OR) for composite subclinical atherosclerosis was 2.34 (95% confidence interval [CI], 1.88–2.91), 1.43 (95% CI, 1.21–1.70), and 0.74 (95% CI, 0.46–1.18), for participants with hyperglycemia who had low, moderate, or high overall CVH scores, respectively, compared with participants with normal glucose regulation. …”
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High-Breakdown and Low-Leakage 4H-SiC MOS Capacitor Based on HfO₂/SiO₂ Stacked Gate Dielectric in Trench Structures by Qimin Huang, Yunduo Guo, Anfeng Wang, Lin Gu, Zhenyu Wang, Chengxi Ding, Yi Shen, Hongping Ma, Qingchun Zhang

“…X-ray photoelectron spectroscopy (XPS) analysis of the gate dielectrics revealed almost identical Hf 4f core levels for both HfO₂ and the SiO₂/HfO₂ composite dielectrics, suggesting that the SiO₂ interlayer and the SiC substrate had minimal impact on the electronic structure of the HfO₂ film. …”
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The physico-chemical characteristics of peel essential oils of sweet orange with respect to cultivars, harvesting times and isolation methods by Burcu Bozova, Muharrem Gölükcü, Haluk Tokgöz, Demet Yıldız Turgut, Orçun Çınar, Ertuğrul Turgutoglu, Angelo Maria Giuffrè

“…Based on the hydrodistillation data, the essential oil ratios ranged between 1.69–2.85 % in samples. …”
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Intensification of Natural Disasters in the State of Pará and the Triggering Mechanisms Across the Eastern Amazon by Everaldo B. de Souza, Douglas B. S. Ferreira, Luciano J. S. Anjos, Alan C. Cunha, João Athaydes Silva, Eliane C. Coutinho, Adriano M. L. Sousa, Paulo J. O. P. Souza, Waleria P. Monteiro Correa, Thaiane S. Silva Dias, Alexandre M. C. do Carmo, Carlos B. B. Gutierrez, Giordani R. C. Sodré, Aline M. M. Lima, Edson J. P. Rocha, Bergson C. Moraes, Luciano P. Pezzi, Tercio Ambrizzi

“…Based on statistical analyses applied to official data from the Digital Atlas of Disasters in Brazil over the last 25 years, we evidenced a consistent intensification in the annual occurrence of natural disasters in the state of Pará, located in the eastern Brazilian Amazon. …”
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An assessment of facility readiness for comprehensive abortion care in 12 districts of Pakistan using the WHO Service Availability and Readiness Assessment tool by Palitha Gunarathna Mahipala, Sabeen Afzal, Qudsia Uzma, Atiya Aabroo, Nilmini Hemachandra, Katy Footman, Heidi Bart Johnston, Bela Ganatra, Tahira Ezra Reza, Ahsan Maqbool Ahmad, Hasan Bin Hamza, Maida Umar, Kauser Hanif, Sayema Awais, Mariyam Sarfraz, Ellen Thom

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Suicide and suicide attempt in users of GLP-1 receptor agonists: a nationwide case-time-control studyResearch in context by Julien Bezin, Anne Bénard-Laribière, Emilie Hucteau, Marie Tournier, François Montastruc, Antoine Pariente, Jean-Luc Faillie

“…Methods: Patients ≥18 y who died by suicide or were hospitalized for suicide attempt (2013–2021) with at least one GLP-1 RA dispensing within the 180 preceding days were selected from the French National Health Data System (SNDS). A case-time-control design compared, for each patient, GLP-1 RA exposure in the 30 days preceding the outcome (composite of suicide or suicide attempt) to three earlier 30-day reference periods. …”
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Ecotype-specific responses of Typha domingensis to microplastics: Antioxidant defense and biochemical adaptations in wetland ecosystems by Muhammad Aqeel, Ali Noman, Saher Nawaz, Noreen Khalid, Muhammad Kashif Irshad, Muhammad Faisal Iqbal, Modhi O. Alotaibi, Motirh Al-Mutairi, Mohamed O. Alshahrani, Nahaa M. Alotaibi, Fahad Mohammed Alzuaibr

“…Analysis revealed distinct MP polymer compositions and shape distributions among ecotypes. …”
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Association Between Size of Left Ventricle and Long‐Term Cardiovascular Events by Yun‐Jiu Cheng, Zi‐Li Liao, Li‐Juan Liu, Yue‐Dong Ma, Xu‐Miao Chen, Ze‐Xuan Wu, Hui‐Qiang Wei, Wei‐Dong Lin, Yi‐Jian Liao, Su‐Hua Wu, Yu‐Mei Xue, Li‐Chun Wang, Yang Wu

“…Cox proportional hazards models were applied to evaluate the association between LV size and composite cardiovascular outcomes. Results An elevated prevalence of small LV was observed among the 4305 participants, with a notable trend toward increased occurrence in older individuals. …”
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Prognostic value of global coronary flow reserve before and after elective percutaneous coronary intervention in patients with chronic coronary syndrome by Kai Nogami, Masahiro Hoshino, Eisuke Usui, Yoshihisa Kanaji, Tomoyo Sugiyama, Masahiro Hada, Tatsuhiro Nagamine, Hiroki Ueno, Mirei Setoguchi, Tomohiro Tahara, Tatsuya Sakamoto, Takashi Mineo, Tsunekazu Kakuta

“…MACCE was defined as a composite of cardiac death, nonfatal myocardial infarction, hospitalization due to heart failure, or ischemic stroke. …”
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Clinical Features and Outcomes of Primary Sclerosing Cholangitis in the Highly Admixed Brazilian Population by Mateus Jorge Nardelli, Paulo Lisboa Bittencourt, Guilherme Grossi Lopes Cançado, Luciana Costa Faria, Cristiane Alves Villela-Nogueira, Vivian Rotman, Eliabe Silva de Abreu, Fernanda Maria Farage Osório, Andreia Silva Evangelista, Liliana Sampaio Costa Mendes, Daniel Ferraz de Campos Mazo, Elodie Bonfim Hyppolito, Adrielly de Souza Martins, Liana Codes, Izabelle Venturini Signorelli, Geisa Perez Medina Gomide, Luciana Agoglia, Claudia Alexandra Pontes Ivantes, Valéria Ferreira de Almeida e Borges, Gabriela Perdomo Coral, Rosamar Eulira Fontes Rezende, Maria Lucia Gomes Ferraz, Debora Raquel Benedita Terrabuio, Eduardo Luiz Rachid Cançado, Claudia Alves Couto

“…The 1- and 5-year survival free of liver transplantation or death were 92.3 ± 2.1% and 66.9 ± 4.2%, respectively, and baseline advanced PSC, pruritus, and elevated bilirubin levels were independent risk factors for the composite adverse outcome. Females were significantly older and had lower bilirubin levels than males at baseline, but survival was not associated with sex. …”
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Inhaled ciclesonide in adults hospitalised with COVID-19: a randomised controlled open-label trial (HALT COVID-19) by Peter Ueda, Johan Hansson, Johan Ljungberg, Anders Krifors, Björn Johansson, Martin Larsson, Per Tornhammar, Daniel Peter Andersson, Daniel Brodin, Eli Westerlund, Simon Athlin, Sandra Wojt, Olof Elvstam, Anca Neumann, Arsim Elshani, Julia Giesecke, Jens Edvardsson-Källkvist, Sayam Bunpuckdee, Christian Unge, Jonas Lindell, Ola Blennow

“…Key secondary outcome was a composite of invasive mechanical ventilation/death.Results Data from 98 participants were analysed (48 receiving ciclesonide and 50 receiving standard care; median (IQR) age, 59.5 (49–67) years; 67 (68%) men). …”
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Semi-quantitative analysis of 18F fluorodeoxyglucose uptake in the assessment of disease activity and therapeutic response in rheumatoid arthritis: An institutional experience by Reddy Ravikanth, Jyotin Singh

“…The number of PET-positive joints and the cumulative SUV significantly correlated with the DAS28, which is a composite disease activity score (DAS) that combines the swollen and tender joint counts, the erythrocyte sedimentation rate (DAS28-ESR) or CRP serum levels (DAS28 − CRP) or RF (DAS28 − RF) or metalloproteinases-3 (DAS28-MMP-3). …”
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Metabolic Acidosis Is Associated With an Accelerated Decline of Allograft Function in Pediatric Kidney Transplantation by Agnieszka Prytula, Rukshana Shroff, Ineke van Gremberghe, Kai Krupka, Justine Bacchetta, Elisa Benetti, Ryszard Grenda, Isabella Guzzo, Nele Kanzelmeyer, Bahar Büyükkaragöz, Birgitta Kranz, Hülya Nalçacıoğlu, Jun Oh, Lars Pape, Mohan Shenoy, Anne-Laure Sellier-Leclerc, Burkhard Tönshoff, Gema Ariceta, Atif Awan, Sevcan Bakkaloğlu, Marjolein Bonthuis, Charlotte Bootsma Robroeks, Antonia Bouts, Martin Christian, Marlies Cornelissen, Ali Duzova, Nasrin Esfandiar, Luciana Ghio, Ryszard Grenda, Isabella Guzzo, Maria Herrero Goni, Julien Hogan, Nattaphorn Hongsawong, Nele Kanzelmeyer, Aysun Karabay Bayazit, Gülşah Kaya Aksoy, Noel Knops, Linda Koster Kamphuis, Daniella Levy Erez, Victor Lopez-Baez, Alvaro Madrid, Stephen Marks, Anette Melk, Luisa Murer, Lars Pape, Licia Peruzzi, Edita Petrosyan, Evgenia Preka, Nikoleta Printza, Andreea Liana Rachisan, Ann Raes, Mohan Shenoy, Oguz Soylemezoglu, Luca Dello Strologo, Ana Teixeira, Rezan Topaloglu, Markus Weitz, Jakub Zieg, Galia Zlatanova, Christian Patry, Jerome Harambat, Ayşe Ağbaş, Varvara Askiti, Marina Avramescu, Justine Bacchetta, Sevcan Bakkaloglu, Marjolein Bontuis, Caroline Booth, Laurene Dehoux, Giacomo Dizazzo, Dorota Drozdz, Ismail Dursun, Michaela Gessner, Jaap Groothoff, Giuliana Guido, Isabella Guzzo, Aysun Karabay Bayazit, Guenter Klaus, Linda Koster-Kamphuis, Alexander Lalayiannis, Maren Leifheit-Nestler, Sinha Manish, Chiara Matteucci, Jun Oh, Ozan Ozkaya, Edita Petrosyan, Christine Pietrement, Agnieszka Prytula, George Reusz, Franz Schaefer, Claus Peter Schmitt, Anne Schön, Fatma Lale Sever, Stella Stabouli, Serra Sürmeli Döven, Camilla Tondel, Enrico Verrina, Enrico Vidal, Dean Wallace, Zainab Arslan, M. Bald, H. Fehrenbach, D. Haffner, M. Hansen, C. Hempel, U. John, G. Klaus, J. König, B. Lange-Sperandio, D. Müller, J. Oh, L. Pape, M. Pohl, K. Sauerstein, G. Schalk, H. Staude, P. Strotmann, L.T. Weber, M. Weitz, L. Berta, K. Heindl-Rusai

“…Methods: This registry study collected data up to 10 years posttransplant. Survival analysis for a composite end point of graft loss or estimated glomerular filtration rate (eGFR) ≤ 30 ml/min per 1.73 m2 or ≥50% decline from eGFR at month 3 posttransplant was performed. …”
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Long-term prognostic impact of the left anterior descending coronary artery as the STEMI-related culprit vessel: subanalysis of the EXAMINATION-EXTEND trial by Pablo Vidal-Calés, Kamil Bujak, Riccardo Rinaldi, Anthony Salazar-Rodríguez, Luis Ortega-Paz, Josep Gómez-Lara, Víctor Jiménez-Díaz, Marcelo Jiménez, Pilar Jiménez-Quevedo, Roberto Diletti, Pascual Bordes, Gianluca Campo, Antonio Silvestro, Jaume Maristany, Xacobe Flores, Antonio De Miguel-Castro, Andrés Íñiguez, Alfonso Ielasi, Maurizio Tespili, Mattie Lenzen, Nieves Gonzalo, Matteo Tebaldi, Simone Biscaglia, Rafael Romaguera, Joan Antoni Gómez-Hospital, Patrick W. Serruys, Manel Sabaté, Salvatore Brugaletta

“…ABSTRACT Introduction and objectives: There is limited data on the impact of the culprit vessel on very long-term outcomes after ST-elevation myocardial infarction (STEMI). …”
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Analysis of genomic selection characteristics of local cattle breeds in Gansu by Bao Cai, Yandong Kang, Lin Xiong, Jie Pei, Qianyun Ge, Xiaoyun Wu, Manyu Gan, Xian Guo

“…By integrating comprehensive genome data from multiple breeds, this study aims to analyze population genetics, detect composite selection signals, and perform functional enrichment to uncover the mechanisms behind genetic differentiation and adaptive evolution. …”
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The bidirectional relationship between severity of obsessive-compulsive symptoms and lifestyle factors in patients with obsessive-compulsive disorder: a contemporaneous and prospec... by Johanna A. M. du Mortier, Anton J. L. M. van Balkom, Anton J. L. M. van Balkom, Jos W. R. Twisk, Patricia van Oppen, Patricia van Oppen, Henny A. D. Visser, Henny A. D. Visser

“…In the present study, drug and alcohol use, higher BMI, and a composite score of unhealthy lifestyle factors were not associated with more severe OCD symptoms and did not predict greater symptom severity two years later. …”
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Mid-term outcome and quality of life after Bentall procedure: single-center experience by I. O. Stetsyuk, L. R. Stetsiuk, B. M. Todurov, I. Yu. Mokryk, V. I. Zaviiskyi, I. P. Nechai, V. B. Demyanchuk, O. V. Zelenchuk

“…The mean age of the 55 patients (53 (96.36 %) males), who underwent the Bentall procedure (composite graft replacement of the aortic root), was 52.36 ± 1.56 years. …”
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