Antiplatelet Use Prior to Anticoagulant Initiation in Patients With Atrial Fibrillation-Related Ischemic Stroke: An ELAN Trial Analysis by Alexandros A. Polymeris, Masatoshi Koga, Daniel Strbian, Adhiyaman Vedamurthy, Manju Krishnan, Mattia Branca, Thomas Horvath, Martina Goeldlin, Gek Shim, Christoph Gumbinger, Liqun Zhang, Espen Saxhaug Kristoffersen, Philippe Desfontaines, Peter Vanacker, Angelika Alonso, Sven Poli, Ana Paiva Nunes, Nicoletta G. Caracciolo, Markus Kneihsl, Timo Kahles, Daria Giudici, Silja Räty, Marjaana Tiainen, Jesse Dawson, Urs Fischer, for the ELAN Investigators

“…Methods A post-hoc analysis of ELAN (Early versus Late Initiation of Direct Oral Anticoagulants in Post-ischemic Stroke Patients with Atrial Fibrillation) trial data (NCT03148457) was conducted to compare the risk of recurrent ischemic stroke, systemic embolism, major bleeding (extracranial or intracranial hemorrhage [ICH]), and vascular death within 30 days (as a composite and as individual outcomes) in participants treated with and without antiplatelets before DOAC initiation after an AF-associated ischemic stroke. …”
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Comparative risk of retinal microvascular disorders in patients with gout initiating febuxostat versus allopurinol: a population-based cohort study by Min Jung Kim, Jung Yoon Pyo, Se Rim Choi, Anna Shin, Hokyung Choung, You-Jung Ha, Yun Jong Lee, Eun bong Lee, Eun Ha Kang

“…Abstract Despite recent accumulation on cardiovascular (CV) safety data on xanthine oxidase inhibitors (XOIs) among gout patients, assessment has been largely limited to macro- than micro-vascular disorders, prompting the investigation on the latter outcome. …”
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Suppress or Not to Suppress … CRAFT It: A Targeted Metabolomics Case Study Extracting Essential Biomarker Signals Directly from the Full ¹H NMR Spectra of Horse Serum Sa... by James Chen, Ayelet Yablon, Christina Metaxas, Matheus Guedin, Joseph Hu, Kenith Conover, Merrill Simpson, Sarah L. Ralston, Krish Krishnamurthy, István Pelczer

“…<b>Background</b>: There are a few very specific inflammation biomarkers in blood, namely lipoprotein NMe⁺ signals of protein clusters (GlycA and GlycB) and a composite resonance of phospholipids (SPC). The relative integrals of these resonances provide clear indication of the unique metabolic changes associated with disease, specifically inflammatory conditions, often related to serious diseases such as cancer or COVID-19 infection. …”
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Modeling the Ages and Chemical Abundances of Elliptical Galaxies by Nicole Marcelina Gountanis, David H. Weinberg, Aliza G. Beverage, Nathan R. Sandford, Charlie Conroy, Mariska Kriek

“…We show that an SSP fit to the spectrum computed from a full GCE model gives ages and abundances close to the light-weighted, logarithmically averaged values of the composite stellar population, 〈age〉, 〈[Mg/H]〉, and 〈[Mg/Fe]〉. …”
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Detecting wetland encroachment and urban agriculture land classification in Uganda using hyper-temporal remote sensing [version 2; peer review: 1 approved, 2 approved with reservat... by Stella Kabiri, Rebecca Ssabaganzi, Beatrice Akello, Molly Allen, Drake Mubiru, Juduth Toma Okuonzia

“…We used MODIS NDVI 16-day composites at a 500-meter spatial resolution to broaden the analysis to distinguish distinctive crops and crop mixtures in the encroached wetlands for urban agriculture using the ISODATA clustering algorithm. …”
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Circulating testosterone levels and health outcomes in chronic obstructive pulmonary disease: results from ECLIPSE and ERICA by Divya Mohan, Carmel M McEniery, Marie Fisk, Joseph Cheriyan, Bruce E Miller, Ruth Tal-Singer, Michael I Polkey, Charlotte E Bolton, Holly Pavey, Ian Wilkinson, Richard Casaburi

“…Multivariate logistic regression was used to determine associations with H-AECOPD during follow-up (3 years ECLIPSE, 4.5 years ERICA), a composite endpoint of cardiovascular hospitalisation and cardiovascular death, and all-cause mortality.Results Mean (SD) testosterone levels were consistent across cohorts; 459 (197) and 455 (200) ng/dL for males in ECLIPSE and ERICA, respectively, and in ERICA females: 28 (56) ng/dL. …”
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Fluoride Release of Fresh and Aged Glass Ionomer Cements after Recharging with High-Fluoride Dentifrice by Fabiana Gouveia Rolim, Allan David de Araújo Lima, Islany Cardoso Lima Campos, Robson de Sousa Ferreira, Carlos da Cunha Oliveira-Júnior, Vera Lúcia Gomes Prado, Glauber Campos Vale

“…Fifteen specimens of GICs (conventional, resin modified, and high viscosity) and composite resin were stored individually in a polystyrene tube containing 2 ml of deionized water (DW), with water replacement every 24 hours. …”
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Experimental Study on Dynamic Response Characteristics of Rural Residential Buildings Subjected to Blast-Induced Vibrations by Jingmin Pan, Dongli Zhang, Zhenghua Zhou, Jiacong He, Long Zhang, Yi Han, Cheng Peng, Sishun Wang

“…Adhering to the principle of stratified arrangement and composite measurement point configuration, an effective and reasonable experimental observation framework was established. …”
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Mechanisms and Optimization of Foam Flooding in Heterogeneous Thick Oil Reservoirs: Insights from Large-Scale 2D Sandpack Experiments by Qingchun Meng, Hongmei Wang, Weiyou Yao, Yuyang Han, Xianqiu Chao, Tairan Liang, Yongxian Fang, Wenzhao Sun, Huabin Li

“…This study elucidates the dynamic plugging mechanisms of foam flooding in heterogeneous thick oil reservoirs through large-scale physical simulations and data fusion, offering direct technical guidance for optimizing foam flooding operations in the Lukqin Oilfield and analogous reservoirs.…”
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Neurodevelopmental Tics with Co-Morbid Functional Tic-like Behaviors: Diagnostic Challenges of a Complex Tourette Syndrome Phenotype by Andrea Eugenio Cavanna, Virginia Caimi, Elisa Capriolo, Matteo Marinoni, Gabriele Arienti, Anna Riva, Renata Nacinovich, Stefano Seri

“…The correct identification of this composite clinical phenotype plays a key role in preventing the misdiagnosis of treatment-resistant TS and implementing tailored treatment interventions.…”
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Surface Defect Detection for Small Samples of Particleboard Based on Improved Proximal Policy Optimization by Haifei Xia, Haiyan Zhou, Mingao Zhang, Qingyi Zhang, Chenlong Fan, Yutu Yang, Shuang Xi, Ying Liu

“…The method integrates the variable action space and the composite reward function and achieves the balanced optimization of different types of defect detection performance by adjusting the scaling and translation amplitude of the detection region. …”
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Investigating the role of job satisfaction and work engagement dynamics in reducing turnover intentions among female bank employees by Nurdjanah Hamid, Wahda Rasyid, Andi Aswan, Insany Fitri Nurqamar, Romi Setiawan, Rianda Ridho Hafizh Thaha

“…The study applied Composite Reliability (CR) and Average Variance Extracted (AVE) to verify that the loading weights and measurement models met the SEM requirements. …”
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Pilot project to study the association of troponin I with cardiovascular events in the population of Russian region by S. A. Shalnova, O. M. Drapkina, A. V. Kontsevaya, E. B. Yarovaya, V. A. Kutsenko, V. A. Metelskaya, A. V. Kapustina, Yu. A. Balanova, O. A. Litinskaya, M. S. Pokrovskaya

“…It was shown that cTnI itself or its logarithm is significantly associated with hard and composite endpoints. The cTnI cut-off point of 12/10 pg/ml (males/females) was associated with hard endpoint, and 6/4 pg/ml — with composite one. …”
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Effects of landslide hazards on quality of stream water and sediments by O. Phewnil, T. Pattamapitoon, N. Semvimol, W. Wararam, K. Duangmal, A. Intaraksa, K. Chunkao, P. Maskulrath, S. Hanthayung, P. Wichittrakarn

“…Soil and sediment samples were compositely collected from the bottom using a stainless-steel spade. …”
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A comparative analysis of environmental differences in the level of cultural development indicators by Negin Fallah Haghighi, Ghasem Ramezanpour Nargesi, Gholamhossein Abdollahzadeh, Zeinab Sharifi

“…Hence, the study was conducted to measure regional differences in the level of cultural development indicators of the provinces to provide a clear picture of cultural facilities and services in the provinces to guide the budget to improve the cultural development of the country.Material and methods: The research method was based on the construction of a composite indicator, the linear norm method was used to free scale, the principal component analysis method to weigh the indicators, the TOPSIS method to construct a composite indicator of provincial development, coefficients of variation and Williamson to calculate inequality, and finally GIS software as well as hierarchical cluster analysis method to classify the level of development of the provinces were applied. …”
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Evaluation of an Alternative Screening Method for Gestational Diabetes Diagnosis During the COVID-19 Pandemic (DIABECOVID STUDY): An Observational Cohort Study by Alba Casellas, Cristina Martínez, Judit Amigó, Roser Ferrer, Laia Martí, Carme Merced, Maria Carmen Medina, Istria Molinero, Marta Calveiro, Anna Maroto, Ester del Barco, Elena Carreras, Maria Goya

“…The secondary outcomes were composite adverse outcomes, including pregnancy complications, delivery complications, and neonatal complications. …”
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Prognostic implications of residual mild coarctation gradient after interventional repair by Wenhao Zhu, Zhiyuan Xia, Congcong Zhou, Junyi Wan, Jingyu Wang, Yihang Li, Jingnan Zhang, Michael Henein, Fang Fang, Gejun Zhang

“…Abstract There is limited data on the prognostic implications of residual mild coarctation (RMC) in patients with repaired native coarctation of the aorta (CoA). …”
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Comprehensive analysis and quantitative assessment of land use/land cover dynamics in Wakiso and Kampala, Uganda: a multi-decadal remote sensing study by Ebaju Gerverse Kamukama, Abraham Okrah, Magara Genesis, Caleb Mensah, Alupot Donnata, Nana Agyemang Prempeh, Emmanuel Yeboah, Isaac Sarfo

“…Supervised classification used a False Colour Composite of blue, green, and red bands, with 2,500–3,000 pixels per LULC category sampled. …”
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Long-term prognosis after acute coronary syndrome due to de novo coronary artery lesions and stent thrombosis in patients on hemodialysis by Sho Nakao, Takayuki Ishihara, Katsuki Okada, Hirota Kida, Takuya Tsujimura, Shota Okuno, Toshiaki Mano, Atsushi Kikuchi, Takashi Morita, Ryu Shutta, Masami Nishino, Shumpei Kosugi, Yasunori Ueda, Yasuhiro Ichibori, Yoshiharu Higuchi, Daisuke Nakamura, Daisaku Nakatani, Shungo Hikoso, Yohei Sotomi, Yasushi Sakata

“…The primary outcome was the 6-year incidence of major adverse cardiac events (MACE) defined as a composite of cardiac death, non-fatal myocardial infarction, target vessel revascularization, and subsequent ST. …”
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Modelling and optimisation of the structural performance of lightweight polypropylene fibre-reinforced LECA concrete by Idris Ahmed Ja'e, Zakaria Che Muda, Mugahed Amran, Agusril Syamsir, Chiemela Victor Amaechi, Ebrahim Hamid Hussein Al-Qadami, Marco Antonio Díaz Huenchuan, Siva Avudaiappan

“…Lightweight fibre-reinforced concrete integrates the advantages of lightweight aggregates with the strength-enhancing properties of fibres, resulting in a lighter composite with enhanced impact and mechanical performance. …”
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