Role of ferroptosis-related IREB2 in the shared genetic etiology between smoking and facial aging: Insights from large-scale genome-wide cross-trait analysis by Xueyao Cai, Weidong Li, Wenjun Shi, Yuchen Cai, Jianda Zhou

“…To investigate the shared genetic architecture between smoking and facial aging, we performed genetic analyses based on genome-wide association studies (GWAS) data. These analyses included linkage disequilibrium score regression (LDSC), pleiotropic analysis under composite null hypothesis (PLACO), functional mapping and annotation (FUMA), and multi-marker analysis of genomic annotation (MAGMA). …”
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Dyeing of silk with isolated bixin based orange yellow natural dye: Kinetic, thermodynamic and colorimetric aspects by Muhammad Ibrahim, Bisma, Shahid Adeel, Al Mojnun Shamim, Mohammad Khajeh Mehrizi, Muhammad Imran, Muhammad Asif Tahir, Rony Mia

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Clinical and demographic factors modify the association between plasma phosphorylated tau‐181 and cognition by Corey J. Bolton, Marilyn Steinbach, Omair A. Khan, Dandan Liu, Julia O'Malley, Logan Dumitrescu, Amalia Peterson, Angela L. Jefferson, Timothy J. Hohman, Henrik Zetterberg, Katherine A. Gifford, for the Alzheimer's Disease Neuroimaging Initiative

“…METHODS Participants were drawn from the Alzheimer's Disease Neuroimaging Initiative (ADNI) and included 1185 adults >55 years of age with plasma p‐tau181 and neuropsychological test data. Linear regression models related plasma p‐tau181 to neuropsychological composite and SCD scores with follow‐up models examining plasma p‐tau181 interactions with cognitive diagnosis, apolipoprotein E (APOE) ε4 carrier status, age, and sex on cognitive outcomes. …”
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Multi-Objective Optimization in Hard Turning of AISI 4140 Steel Using Taguchi-Based GRA and DEAR with Ceramic Tool by Mohand Ouidir Sahbi, Sadeddine Abdelhamid, Mohamed Athmane Yallese, Salim Belhadi, Abdelatif Belamri

“…Four factors were varied: cutting speed (Vc), feed rate (f), depth of cut (Doc), and cutting tool material (mixed ceramic CC650, TiN-coated mixed ceramic CC6050, and composite ceramic CC670). The experimental results were carefully measured after each test, and ANOVA was performed to analyze the influence of input parameters on the output variables. …”
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Evaluation of Marginal Fit of CAD/CAM Ceramic Crowns and Scanning Time Using Different Intraoral Scanning Systems by Leandro Maruki Pereira, Bárbara Inácio de Melo, Alex Antônio Maciel Oliveira, Gustavo Mendonça, Luís Henrique Araújo Raposo, Marcel Santana Prudente, Flávio Domingues das Neves

“…A standardized, 3D-printed composite resin die with a full-crown tooth preparation was scanned ten times with each IOS, and the scanning time was recorded. …”
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Mare Volcanism in Apollo Basin Evaluating the Mare Basalt Genesis Models on the Moon by Xiaohui Fu, Chengxiang Yin, Jin Li, Jiang Zhang, Siyue Chi, Jian Chen, Bo Li

“…The Apollo basin has been flooded and filled with large volumes of mare lavas, indicating an active volcanism history. Based on orbital data, we reveal that the Apollo basin exhibits an overall asymmetric configuration in the distribution of mare basalts as well as its topography, chemical compositions, and crustal thickness. …”
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Antioxidant hybrid pigments developed by optimization of ascorbic acid loading into halloysite nanotubes via response surface methodology and co-loading with antioxidant-rich natur... by Natthawadee Tibkawin, Nichapa Buasumrit, Panatpong Boonnoun, Sukunya Ross, Gareth Ross, Brian Tighe, Jarupa Viyoch, Pensri Charoensit

“…The analysis of variance showed the resultant data fitted a quadratic polynomial model, which suggested the optimal conditions were 52.76 mg/mL of AA concentration, 19.47 mg of HNTs amount, and 250.91 min of stirring time. …”
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Association between gestational weight gain and severe adverse birth outcomes in Washington State, US: A population-based retrospective cohort study, 2004-2013. by U Vivian Ukah, Hamideh Bayrampour, Yasser Sabr, Neda Razaz, Wee-Shian Chan, Kenneth I Lim, Sarka Lisonkova

“…Optimal, low, and excess weight gain in each BMI category was calculated based on weight gain by gestational age as recommended by the American College of Obstetricians and Gynecologists and the Institute of Medicine. Primary composite outcomes were (1) maternal death and/or severe maternal morbidity (SMM) and (2) perinatal death and/or severe neonatal morbidity. …”
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Multivariable Analysis of Primary Care Physician Adherence to Guideline-recommended Pharmacotherapy of Stable Coronary Artery Disease by S. K. Zyryanov, S. B. Fitilev, A. V. Vozzhaev, I. I. Shkrebniova

“…Pharmacotherapeutic guideline adherence index (PGAI) was introduced as composite quality indicator, calculated in line with “all-or-none” rule and in regard with documented contraindications. …”
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Dental Students’ Perception and Self-Perceived Confidence Level in Key Dental Procedures for General Practice and the Impact of Competency Implementation on Their Confidence Level,... by Wijdan R. Elmanaseer, Salah A. Al-Omoush, Rasha A. Alamoush, Rawan Abu Zaghlan, Firas Alsoleihat

“…The same applies to 6 out of 16 conservative dentistry procedures: placing anterior composite (4.41 vs. 4.12), placing posterior composite (4.43 vs. 3.88), placing posterior amalgam (4.29 vs. 4.02), placing matrix band for Class II restorations (4.24 vs. 3.71), placing a prefabricated post (3.34 vs. 2.88), and placing fiber post (3.45 vs. 3.34). …”
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Impact of antihypertensive drug classes on cardiovascular outcomes: insights from the STEP study by Xinyi Peng, Michael Hecht Olsen, Manan Pareek, Jingjing Bai, Yang Liu, Qirui Song, Jun Cai

“…Methods This study utilised data from the STEP trial, which enrolled elderly, hypertensive Chinese patients with no history of stroke. …”
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Azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a phase II randomised controlled trial by Roisin Connon, Peter Olupot-Olupot, Arthur M. A. Pistorius, William Okiror, Tonny Ssenyondo, Rita Muhindo, Sophie Uyoga, Ayub Mpoya, Thomas N. Williams, Diana M. Gibb, A. Sarah Walker, Rob ter Heine, Elizabeth C. George, Kathryn Maitland

“…We generated relevant pharmacokinetic (PK) data by sparse sampling during dosing intervals and investigated associations between azithromycin exposure and potential mechanisms (PK-pharmacodynamics) using change in C-reactive protein (CRP), a putative marker of sepsis, at 72 h (continuous) and microbiological cure (7-day) (binary), alone and as a composite with 7-day and 90-day survival. …”
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Influence of Co2+ ions doping in Ni0.7-xCoxZn0.3Fe2O4 nanoferrites: A study of structural, morphological, optical, and magnetic properties by Baye Zinabe Kebede, Deepshikha Rathore, Khalid Mujasam Batoo, Paulos Taddesse Shibeshi

“…Among the samples, the nanoferrite with x  = 0.4 exhibited the maximum value of Ms, while x  = 0.5 demonstrated the highest values of Mr and Hc, suggesting the impact of Co concentration on optimizing magnetic properties across different compositions. Hence, x  = 0.4 and 0.5 compositions of Ni0.7-xCoxZn0.3Fe2O4 nanoferrites would be strong candidates for electronic devices like sensors and memory strage.…”
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Petrological and geochemical characteristics of mafic rocks from the Neoproterozoic Sugetbrak Formation in the northwestern Tarim Block, China by Hong-zhe Xie, Xiang-kun Zhu, Xun Wang, Yuan He, Wei-bing Shen

“…All the mafic rocks in this region also showed similar geochemical compositions. They were characterised by high TiO2 contents (1.47% –3.59%) and low MgO (3.52% –7.88%), K2O (0.12% –1.21%). …”
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Clinical Outcomes in Diabetic Females Presenting with STEMI: A Cohort Study by Anjana Ajith Beena, Priya Shanmukhan, Veena Felix, Alummoottil George Koshy, Kunjukrishnapilla Sivaprasad

“…Primary angioplasty was performed in 77%, while thrombolysis was done in 16.7%. The composite outcome was observed in 26.3% of the patients, with heart failure occurring in 19%, cardiogenic shock in 27.9% and death in 16.2%. …”
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A Density Functional Theory-Based Particle Swarm Optimization Investigation of Metal Sulfide Phases for Ni-Based Catalysts by Houyu Zhu, Xiaohan Li, Xiaoxin Zhang, Yucheng Fan, Xin Wang, Dongyuan Liu, Zhennan Liu, Xiaoxiao Gong, Wenyue Guo, Hao Ren

“…Under typical reactive adsorption desulfurization conditions, the ab initio thermodynamics analysis indicates that Ni₃S₂ is the most stable sulfide phase, consistent with sulfur K-edge XANES data. Unsaturated phases, including Ni₃S, Ni₂S, and Ni₉S₅, represent intermediate states towards saturation, potentially explaining the diverse Ni sulfide compositions observed in experiments.…”
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The Role of Prenatal Exposure to Lead and Manganese in Child Cognitive Neurodevelopment at 18 Months: The Results of the Italian PHIME Cohort by Valentina Rosolen, Fabiano Barbiero, Marika Mariuz, Maria Parpinel, Luca Ronfani, Liza Vecchi Brumatti, Maura Bin, Luigi Castriotta, Francesca Valent, D’Anna Latesha Little, Janja Snoj Tratnik, Darja Mazej, Ingrid Falnoga, Milena Horvat, Fabio Barbone

“…Using simple and multiple linear regressions, the study examined the relationship between the cognitive composite score (COGN) and Mn and Pb co-exposure, including their interaction. …”
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Neurodevelopmental outcomes of very low birth weight preterm infants during the COVID-19 pandemic by Yen-Chen Lin, Hung-Yang Chang, Chia-Huei Chen, Jui-Hsing Chang, Wai-Tim Jim, Chyong-Hsin Hsu, Chia-Ying Lin, Yu-Xiang Song, Cheng-Wei Chen, Tzu-Yu Liu, Mary Hsin-Ju Ko

“…No significant differences were observed in the composite cognitive, language, and motor scores between two groups. …”
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Integrated molecular and functional characterization of the intrinsic apoptotic machinery identifies therapeutic vulnerabilities in glioma by Elizabeth G. Fernandez, Wilson X. Mai, Kai Song, Nicholas A. Bayley, Jiyoon Kim, Henan Zhu, Marissa Pioso, Pauline Young, Cassidy L. Andrasz, Dimitri Cadet, Linda M. Liau, Gang Li, William H. Yong, Fausto J. Rodriguez, Scott J. Dixon, Andrew J. Souers, Jingyi Jessica Li, Thomas G. Graeber, Timothy F. Cloughesy, David A. Nathanson

“…This work demonstrates how complementary functional and molecular data can robustly predict therapy-induced cell death.…”
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CarotidSCORE.RU — risk stratification for complications after carotid endarterectomy by A. N. Kazantsev, D. D. Khasanova, A. D. Alpatskaya, A. V. Korotkikh, M. O. Dzhanelidze, M. A. Rusakova, E. U. Kharchilava, M. V. Sulimenko, V. A. Lutsenko, R. V. Sultanov, F. R. Alizada, E. O. Meleshin, E. R. Ginzburg, A. E. Gofman, E. O. Alekseeva, R. Yu. Lider, A. A. Pivovarov, A. B. Zakeryaev, G. Sh. Bagdavadze, M. M. Makoeva, A. I. Klimova, A. S. Zharova, I. A. Chernyavtsev, O. O. Abramov, K. L. Zakharova, I. M. Radzhabov, I. A. Karmokov, A. P. Kuklev, K. N. Solotenkova, M. G. Pachkoria, I. S. Sem’in, A. A. Kostenkov, K. P. Chernykh

“…The composite endpoint was recorded in 0,68%. For each factor present in patients, a predictive coefficient was estimated. …”
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