Use of Beta-Blockers as a First-Line Treatment for Primary Hypertension by Maryam Izadi, Shiva Shafabakhsh, Amir Mirnateghi

“…Therefore, this study aimed to clarify beta-blocker efficacy by incorporating the data from all relevant beta-blocker trials, using the composite outcome of major cardiovascular events. …”
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A Novel, Low-Cost Glaucoma Calculator to Identify Glaucoma Patients and Stratify Management by Daniel Laroche, Kara Rickford, Elise V. Mike, Liane Hunter, Ezekiel Ede, Chester Ng, John Douglas

“…We retrospectively examined data from 104 eyes of patients who underwent a complete ocular examination, visual field, and corneal pachymetry at Advanced Eye Care of New York (54 with glaucoma and 50 controls). …”
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Serum phospholipids and sphingolipids are linked to early-stage osteoarthritis by lipidomic profiling by Gerrit Eichner, Gerhard Liebisch, Christiane Hild, Markus Rickert, Juergen Steinmeyer

“…Results Human SF and serum had similar PL and SL compositions. Quantifying 91 lipid species from 6 major classes revealed OA-related changes in serum, with the lowest levels in healthy controls and elevated levels already in the eOA cohort. …”
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Radar Echo Extrapolation Based on Translator Coding and Decoding Conditional Generation Adversarial Network by Xingang Mou, Yuan He, Wenfeng Li, Xiao Zhou

“…This design serves to effectively steer the generator’s output, thereby augmenting the realism of the produced images. Lastly, a composite multi-loss function is proposed to enhance the network’s capability to model intricate spatiotemporal evolving radar echo data, facilitating a more comprehensive assessment of the quality of the generated images, which in turn fortifies the network’s robustness. …”
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Inverse association of oxidative balance score with depression and specific depressive symptoms among cancer population: Insights from the NHANES (2005-2020). by Hanli Bu, Mingzhen Lv, Linxian Wang, Dan Jiang, Yi Ding, Zheya Wang, Yaoyao Hu, Qin Zhuang, Zhenzhen Tian

“…This study examines the relationship between the Oxidative Balance Score (OBS)-a composite measure of dietary and lifestyle factors-and depression, including specific depressive symptoms in this population.…”
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Modeling the factors that explain customer loyalty in retail banking by Marko van Deventer, Ephrem Habtemichael Redda

“…Moreover, the measurement model returned acceptable composite reliability together with construct, convergent and discriminant validity. …”
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Predictors of Successful Memory Aging in Older Mexican Adults by Rosa Estela García-Chanes, Luis Miguel Gutiérrez-Robledo, Teresa Álvarez-Cisneros, Paloma Roa-Rojas

“…To date, little is known about the association between successful memory aging and intrinsic capacity (IC) defined as “the composite of all the physical and mental (including psychosocial) capacities that an individual can draw on at any point in time” and resilience. …”
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Restoration of normal occlusal relations in the complex treatment of patients with generalized periodontitis and bounded edentulous spaces by A. S. Melnychuk, M. M. Rozhko, H. M. Melnychuk

“…After evaluation of the dental occlusion relationships, all patients were performed a complex treatment of GP by selective grinding or occlusal surface adjustment with a composite material under the control of the apparatus “T-Scan III”, achieving the most correct distribution of occlusal contacts. …”
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Associations of handgrip strength asymmetry with physical frailty, cognitive impairment, and cognitive frailty: A cross-sectional finding from the Longitudinal Ageing Study in Indi... by Inderdeep Kaur, Nirmal Nath Upadhyay, Shivani Chandel

“…Physical frailty was assessed using the Modified Fried Frailty Phenotype and Cognitive impairment with the Composite Cognitive Impairment Index (CII). HGS asymmetry was calculated using hand grip ratios. …”
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Study on the evolution patterns and predictive modeling of ambient air quality in oasis cities of arid regions: a case study of Urumqi by Bian Jing, Ren Xiaofeng

“…BackgroundThis study investigates the evolution patterns and future trends of ambient air quality in oasis cities within arid regions, with Urumqi as a representative case.MethodsUtilizing observational data from eight urban monitoring stations, we comprehensively analyze air quality variations and project future scenarios through the Air Quality Index (AQI), Spearman’s rank correlation coefficient, and Grey correlation modeling. …”
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Formulation Development of Directly Compressible Tablets Incorporating Trisamo Extract With Synergistic Antioxidant Activity by Jirapornchai Suksaeree, Thaniya Wunnakup, Natawat Chankana, Laksana Charoenchai, Chaowalit Monton

“…This work investigates the synergistic antioxidant activity of the compositions of Trisamo (TSM) herbal formula containing the dried fruits of Terminalia chebula, Terminalia arjuna, and Terminalia bellirica. …”
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C-reactive protein-triglyceride glucose index and heart failure in US adults from NHANES 2001–2010 by Ningyi Cheng, Zhicheng Ma, Yukun Chen, Lei Jin, Liangwan Chen

“…Abstract The C-reactive protein(CRP)-triglyceride glucose index (CTI) is a new composite biomarker used to assess inflammation and insulin resistance(IR) severity. …”
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Assessing spatial and seasonal variability in soil organic carbon fractions of teal carbon in semi-arid Ramsar wetlands of India as a natural climate solution by Shubham Kumar, Laxmi Kant Sharma

“…Ground-based laboratory observations and remote sensing data (19 for SL and 12 for KNP soil depth composite samples) were used. …”
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Integrated genetic analysis of Alzheimer's disease and stroke subtypes: insights from LDSC, PLACO, and MR studies by Yu Long, Jinfeng Liu, Jinniu Guo, Jinzhao Jiang, Xiangyu Wang, Ruohan Sun

“…Methods The Linkage Disequilibrium Score Regression (LDSC) for heritability and genetic correlations, Polygenic Likelihood Ratio under a Composite Null Hypothesis (PLACO) method for pleiotropic loci and locus, and Functional maps and annotations from genome-wide association studies (FUMA) for function analysis of multi-effect loci, multi-marker analysis of genoMic annotation (MAGMA) for gene tissue specificity, Mendelian Randomization (MR) analyses for causal relationships between AD and five stroke subtypes were performed through Single Nucleotide Polymorphism (SNP) heritability enrichments and causal associations were analyzed using comprehensive GWAS data. …”
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Experimental study on preparedness of disease X with an agent-based framework scenario-driven analysis by Dmytro Chumachenko

“…A 70 % mRNA supply shortfall lasting 35 days increases deaths by 7%, and seeding 50 immune-escape cases (R0≈9.5, 60 % neutralization loss) increases cumulative mortality by 41 % within six weeks. The composite conflict shock elevates deaths by 71 % despite a 10% population outflow. …”
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Investigation into the Hyperparameters of Error-Based Adaptive Sampling Approach for Surrogate Modeling by Leonid Legashev, Sergey Tolmachev, Irina Bolodurina, Alexander Shukhman, Lyubov Grishina

“…The best results were shown by the composite Mixed Sampling method with a data refining window the size of 70% and a LightGBM regression model. …”
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Advanced machine learning techniques for predicting compressive strength and ultrasonic pulse velocity of concrete incorporating industrial by-products by Ehsan Mohsennia, Alireza Javid, Vahab Toufigh

“…This study introduces a novel, dual-stage machine learning framework that uniquely integrates both physical mix parameters and detailed chemical compositions of cement and multiple industrial by-products (IBPs)—including fly ash, GGBFS, silica fume, and metakaolin—into a unified predictive model. …”
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Potential utility of salivary gland amyloid uptake as a surrogate marker for adipose tissue and amyloid-beta dynamics based on its association with BMI and cerebral amyloid burden by Kyu Ri Kim, Kyungmin Kim, Ji-Young Kim, Hai-jeon Yoon

“…Multiple regression analysis identified BMI as an independent predictor of composite brain SUVR (β = -0.0168, p = 0.0046), while SUVRSG was marginally significant (β = -0.0714, p = 0.0701). …”
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Study on the Influence Mechanism of Machine-Learning-Based Built Environment on Urban Vitality in Macau Peninsula by Chen Pan, Jiaming Guo, Haibo Li, Jiawei Wu, Nengjie Qiu, Shengzhen Wu

“…Two factors, population vitality and microblogging check-in vitality, contributed the most to the composite vitality value. Secondly, road network density was the most important built environment factor affecting urban vitality in Macau Peninsula (SHAP = 0.025). …”
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The role of MRO as an M2 macrophage-associated gene in non-small cell lung cancer: insights into immune infiltration, prognostic significance, and therapeutic implications by Yue Gu, Miaosen Zheng, Jing Xie

“…Single-cell RNA sequencing data from TISCH2 evaluated MRO expression in different cell types. …”
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