Zika Virus Infection Modulates Extracellular Vesicle Biogenesis and Morphology in Human Umbilical Cord Endothelial Cells: A Proteomic and Microscopic Analysis by Manuel Adrián Velázquez-Cervantes, Arturo Flores-Pliego, Yazmín Rocío Benitez-Zeferino, Victor Javier Cruz-Holguín, Luis Herrera Moro-Huitron, Addy Cecilia Helguera-Repetto, David Eduardo Meza-Sánchez, José Luis Maravillas-Montero, Nicolás Cayetano-Castro, Javier Mancilla-Ramírez, Aurora Casarrubias-Betancourt, Guadalupe León-Reyes, Macario Martínez-Castillo, Isabel Wong-Baeza, Luis Adrián De Jesús-González, María Isabel Baeza-Ramírez, Moisés León-Juárez

“…Future studies aimed at the proteomic and lipidomic composition analyses of these EVs are needed to understand the biological implications in vertical infection.…”
Get full text

Probing Chemical Enrichment in Extremely Metal-poor Galaxies by Keita Fukushima, Kentaro Nagamine, Akinori Matsumoto, Yuki Isobe, Masami Ouchi, Takayuki R. Saitoh, Yutaka Hirai

Get full text

Lightweight anomaly detection model for UAV networks based on memory-enhanced autoencoders by HU Tianzhu, SHEN Yulong, REN Baoquan, HE Ji, LIU Chengliang, LI Hongjun

“…The composite statistical characteristics of the data flow were calculated based on the damped window model, and the memory complexity in the calculation process was reduced in an incremental update manner. …”
Get full text

Comparison of methods for calculating the enthalpy of vaporization of binary azeotropic mixtures by D. A. Ryzhkin, V. M. Raeva

“…Arrays of calculated data were obtained with regard to molar enthalpies of vaporization for 25 compositions of binary azeotropes (isothermal, isobaric conditions of phase equilibrium), and the full range of compositions of the benzene–ethanol system at atmospheric pressure.Conclusions. …”
Get full text

Radiofrequency echographic multi-spectrometry for early bone health: The REMS-bone study protocol (Trial acronym: REMS-bone) by Serafina Perrone, Malgorzata Wasniewska, Maria-Elisabeth Street, Virginia Beretta, Elena Scarpa, Chiara Petrolini, Andrea Dall’Asta, Domenico Corica, Tommaso Aversa, Giorgia Pepe, Letteria Morabito, Federica Grassi, Anna-Mariia Shulhai, Valentina Bianco, Anna Maria Papini, Maria Cristina Albertini, Silvia Carloni, Giuseppe Maglietta, Matteo Puntoni, Caterina Caminiti, Francesco Conversano, Tullio Ghi

“…Discussion: This study is designed to provide robust data on the best method to identify and evaluate bone status starting from intrauterine life. …”
Get full text

Handgrip strength and menopause are associated with cardiovascular risk in women with obesity: a cross-sectional study by Jaqueline de Paula Chaves Freitas, Joyce Noelly Vitor Santos, Daniela Barreto de Moraes, Gabriele Teixeira Gonçalves, Leonardo Augusto da Costa Teixeira, Maria Thereza Otoni Figueiró, Tamara Cunha, Vanessa Kelly da Silva Lage, Ana Lúcia Danielewicz, Pedro Henrique Scheidt Figueiredo, Henrique Silveira Costa, Alessandro Sartorio, Thyago José Silva, Fidelis Antônio da Silva Júnior, Cheyenne Alves Fonseca, Elizabethe Adriana Esteves, Ana Cristina Rodrigues Lacerda, Vanessa Amaral Mendonça

“…Dual X-ray Absorptiometry was used to assess body composition. Additionally, clinical and biochemical parameters, along with HGS, were evaluated. …”
Get full text

Physics-based Simulation of the 2013 April 11 Solar Energetic Particle Event by Weihao Liu, Igor V. Sokolov, Lulu Zhao, Tamas I. Gombosi, Nishtha Sachdeva, Xiaohang Chen, Gábor Tóth, David Lario, Ward B. Manchester IV, Kathryn Whitman, Christina M. S. Cohen, Alessandro Bruno, M. Leila Mays, Hazel M. Bain

“…Observations from multiple spacecraft, including the Solar and Heliospheric Observatory, Solar Dynamics Observatory, Geostationary Operational Environmental Satellite, Advanced Composition Explorer near Earth, and STEREO-A/B, are used for model–data comparison and validation. …”
Get full text

Himatanthus bracteatus stem bark ethanolic extract obtained by sequential pressurized liquid extraction: Chromatographic characterization and profiling of cytotoxic, antitumoral an... by Rose N. Pereira-Filho, Wilson D. Gonçalves-Júnior, Agenor G. dos Santos-Neto, John L.S. Cunha, Oslei P. de Almeida, Luciana N. Andrade, Daniela Droppa-Almeida, Ricardo G. Amaral, Cláudio Dariva, Juliana C. Cardoso, Patricia Severino, Eliana B. Souto, Ricardo L.C. de Albuquerque-Júnior

“…Chromatographic analysis revealed the major EEHB composition in dimethyl isoplumerideo acid, 13-deoxyplumerido, isoplumeride, and plumeride. …”
Get full text

Effect of elite sport activity on salivary microbiota: The case of water polo by Iolanda Veneruso, Cristina Mennitti, Alessandro Gentile, Gennaro Di Bonito, Jacopo Ulisse, Carmela Scarano, Barbara Lombardo, Daniela Terracciano, Raffaela Pero, Giovanni D'Alicandro, Giulia Frisso, Valeria D'Argenio, Olga Scudiero

“…Moreover, gut microbiota alterations have been associated to an increasing number of diseases and its composition can be affected by several factors, including physical exercise. …”
Get full text

Ameliorative effects of E. cristatum fermented albino tea at the regreening stage on fat deposition of youth chicken by Tianjin Lin, Weicheng Lu, Xiaohui Zhou, Xi Li, Shengjian Zeng, Shungeng Li, Chaoyue Yan, Renjie Zhu, Guodong Cai, Wanglong Zheng, Hui Zou, Zongping Liu, Jianchun Bian

“…The results showed that EFAT supplementation improved the efficiency of feed resource utilization and reduced production costs by observing the growth data and calculating feed conversion ratio (FCR). …”
Get full text

Short-term incremental prednisone therapy in patients with serologically active clinically quiescent lupus nephritis: a retrospective observational study by Ning An, Hao-tao Chen, Wen-bo Deng, Le Zhang, Jin-xia Chen, Cui-wei Yao, Hua-feng Liu, Yong-zhi Xu

“…Results No significant differences in sex, age, disease course, maintenance treatment composition, or laboratory tests between the two groups were observed, except for serum complement C3 levels, which were significantly lower in patients in the prednisone increment group than in controls (P = 0.025). …”
Get full text

Sources of uncertainty in DNA metabarcoding of whole communities: Implications for its use in biomonitoring by J. Iwan Jones, Amanda Arnold, Dominik Buchner, John F. Murphy, Jasmine N. Childress, Pedro Beja, Florian Altermatt, Kristian Meissner, Ian Adams, Meri Anderson, Yaisel J. Borrell, Andrew G. Briscoe, Kat Bruce, Cátia Chaves, Chris Conyers, Kristy Deiner, Vasco Elbrecht, Álvaro Fueyo, Tim Goodall, Javier Granero‐Castro, Cristina Hartmann‐Fatu, Eleanor Jones, Elvira Mächler, Filipa M. S. Martins, Sam McGreig, Lyndall Pereira‐da‐Conceicoa, James L. Pretty, Daniel S. Read, Ben Price, Florian Leese, Rosetta C. Blackman

“…Hierarchical nested analyses were used to identify sources of uncertainty in the data and explore factors influencing the returned community and metrics of ecosystem quality. …”
Get full text

Evaluation of the innate immunostimulatory potential of originator and non-originator copies of insulin glargine in an in vitro human immune model. by Ernesto Luna, Pankaj Agrawal, Riyaz Mehta, Maria E Boone, Charlotte Vernhes, Colombe Denys, Robert Small, Bhaswati Mukherjee, Norbert Tennagels, Stefan Maerten, Donald R Drake

“…<h4>Conclusion</h4>The data presented here suggests some non-originator insulin glargine product lots drive heightened in vitro human innate activity and provides preliminary evidence that changes in the biochemical composition of non-originator insulin glargine products (dimers, impurities) might be responsible for their greater immunostimulatory potential.…”
Get full text

Prevalence of sarcopenia and its association with clinical features and health-related quality of life in Brazilian women with systemic lupus erythematosus by Vanessa Hax, Poli Mara Spritzer, Rosa Weiss Telles, Rafaela Cavalheiro do Espirito Santo, Emerson Pena, Leonardo Peterson dos Santos, Lucas Denardi Dória, Stephanie Pilotti, André Luiz Silveira Mallmann, Daniel Nóbrega de Moraes, Clarice Moura Mata Machado, Cristina Costa Duarte Lanna, Olivio Brito Malheiro, Emanoel Luis da Silveira, Fabiana de Miranda Moura, Andrese Aline Gasparin, Tayane Muniz Fighera, Rafael Mendonça da Silva Chakr, Ricardo Machado Xavier, Odirlei André Monticielo

“…Data collected included clinical features and HRQoL. …”
Get full text

The <i>ARK2N</i> (<i>C18ORF25</i>) Genetic Variant Is Associated with Muscle Fiber Size and Strength Athlete Status by Rukiye Çığırtaş, Celal Bulgay, Hasan Hüseyin Kazan, Onur Akman, Goran Sporiš, George John, Rinat A. Yusupov, Rinat I. Sultanov, Andrey V. Zhelankin, Ekaterina A. Semenova, Andrey K. Larin, Nikolay A. Kulemin, Edward V. Generozov, Damir Jurko, Ildus I. Ahmetov

“…Background: Data on the genetic factors contributing to inter-individual variability in muscle fiber size are limited. …”
Get full text

The Effect of Probiotics on Preterm Birth Rates in Pregnant Women After a Threatened Preterm Birth Episode (The PROPEV Trial) by Ester del Barco, Leidy-Alejandra G. Molano, Mireia Vargas, Marta Miserachs, Linda Puerto, Carmen Garrido-Giménez, Zaida Soler, Begoña Muñoz, Laia Pratcorona, Sonia Rimbaut, Mercè Vidal, Marta Dalmau, Alba Casellas, Elena Carreras, Chaysavanh Manichanh, Maria Goya

“…Therefore, this study explored the impact of vaginal probiotics on perinatal outcomes and vaginal microbiota composition in pregnant women at risk of preterm birth. …”
Get full text

Methylation and gene expression patterns in adamantinomatous craniopharyngioma highlight a panel of genes associated with disease progression-free survival by Junier Marrero-Gutiérrez, Ana Carolina Bueno, Ana Carolina Bueno, Clarissa Silva Martins, Rui Milton Patrício Silva-Júnior, Antônio Carlos dos Santos, Marcelo Volpon Santos, Luiz Eduardo Wildemberg, Ximene Lima da Silva Antunes, Monica R. Gadelha, Ayrton Custodio Moreira, Ricardo Zorzetto Nicoliello Vêncio, Sonir Roberto R. Antonini, Margaret de Castro

“…The strong concordance between methylation and transcriptomic data in the 212- and 37-gene sets underscores their potential as a clinically relevant molecular biomarker panel. …”
Get full text

Large MAF transcription factors reawaken evolutionarily dormant fast-glycolytic type IIb myofibers in human skeletal muscle by Shunya Sadaki, Ryosuke Tsuji, Takuto Hayashi, Masato Watanabe, Ryoto Iwai, Gu Wenchao, Ekaterina A. Semenova, Rinat I. Sultanov, Andrey V. Zhelankin, Edward V. Generozov, Ildus I. Ahmetov, Iori Sakakibara, Koichi Ojima, Hidetoshi Sakurai, Masafumi Muratani, Takashi Kudo, Satoru Takahashi, Ryo Fujita

“…RNA-seq and flux analyzer data revealed that large MAFs significantly enhanced glycolytic capacity by upregulating the expression of key genes involved in glucose metabolism. …”
Get full text

Morpho-phenotypic characterization of melanoma brain metastases immune microenvironment: A multicentre retrospective study by Filippo Nozzoli, Marco Gessi, Filippo Ugolini, Sara Simi, Luca Tinunin, Luigi Francesco Iannone, Alice Esposito, Giovanni Muscas, Alessandro Della Puppa, Isabella Ciardetti, Nicola Pimpinelli, Vincenzo De Giorgi, Isacco Desideri, Lorenzo Livi, Laura Doni, Giovanni Schinzari, Ernesto Rossi, Mario Mandalà, Daniela Massi

“…Introduction: The recent rise of immunotherapy for melanoma brain metastases (MBM) has enhanced the interest in characterizing the composition of local immune microenvironment. Despite the central nervous system (CNS) is well known for harbouring a peculiar immunological milieu, its role in MBM is only partially understood. …”
Get full text

ID1 and ID3 functions in the modulation of the tumour immune microenvironment in adult patients with B-cell acute lymphoblastic leukaemia by Nathaly Poveda-Garavito, Nathaly Poveda-Garavito, Nathaly Poveda-Garavito, Carlos A. Orozco Castaño, Carlos A. Orozco Castaño, Yulieth Torres-Llanos, Yulieth Torres-Llanos, Yulieth Torres-Llanos, Nataly Cruz-Rodriguez, Rafael Parra-Medina, Rafael Parra-Medina, Sandra Quijano, Jovanny Zabaleta, Alba Lucia Combita, Alba Lucia Combita, Alba Lucia Combita

“…B-ALL progression alters immune cell composition and the bone marrow (BM) microenvironment, impacting disease progression and therapy response. …”
Get full text