Bridging the gap in Chagas disease management: a mixed-methods study using an implementation science approach within the Brazilian primary health care system—‘Implementa-Chagas/SaMi-Trop project’Research in context by Carlos Henrique Valente Moreira, Laura Azevedo, Ariela Mota Ferreira, Ana Carolina Gonçalves Oliveira, Andréia Brito de Souza, Desirée Sant’Ana Haikal, Cláudia Di Lorenzo Oliveira, Clareci Silva Cardoso, Matthew Spinelli, Ana Luiza Bierrenbach, Nayara Dornela Quintino, Nayara Ragi Baldoni, Renata Fiuza Damasceno, Malu Ribeiro Drumond, Thallyta Maria Vieira, Dardiane Santos Cruz, Sâmara Fernandes Leite, Ana Clara de Jesus Santos, Léa Campos de Oliveira Silva, Renata Buccheri, Antônio Luiz Pinho Ribeiro, Ester Cerdeira Sabino

Get full text

Implementation Of The Inquiry Learning Model On The Study Of AlQur'an Hadith Class X Man 01 Way Right Students (Case Study of Class X Students at MAN 1 Way Kanan) by Amin Siddik, Anggiani Sri Kinanti, Ahadi Sapron

“…The problem formulation for this thesis is: How to Implement the Inquiry Learning Model in the Al-Qur'an Hadith Subject (Case Study for Class X MAN 1 Way Kanan Students) for the 2020/2021 Academic Year. …”
Get full text

Facilitators, barriers, and guidance to successful implementation of multidisciplinary transitional care interventions: A qualitative systematic review using the consolidated frame... by Romain Collet, Juul van Grootel, Marike van der Leeden, Marike van der Schaaf, Johanna van Dongen, Suzanne Wiertsema, Edwin Geleijn, Mel Major, Raymond Ostelo

“…Numerous studies have evaluated patients’, family members’, and healthcare professionals’ experiences with multidisciplinary transitional care interventions, which can provide insight into facilitators and barriers to their implementation. …”
Get full text

Unique target binding by the C-terminal region of FHR1 provides a new perception of aHUS pathology by Luce Perie, Selina Stippa, Christoph Saffer, Christoph Saffer, Andrea Hartmann, Mathias Mörgelin, Svante L. H. Zipfel, Marc Thilo Figge, Marc Thilo Figge, Thorsten Wiech, Christine Skerka, Peter F. Zipfel, Peter F. Zipfel

“…The variants and mutant proteins were tested in binding studies to C3b , C3d and heparin, in hemolytic assays and for the induction of inflammatory cytokines. …”
Get full text

Community advisory board members’ perspectives on their contributions to a large multistate cluster RCT: a mixed methods study by Julie Bosak, Mari-Lynn Drainoni, Mia-Cara Christopher, Bethany Medley, Sandra Rodriguez, Sydney Bell, Erin Kim, Caroline Stotz, Greer Hamilton, Carol Bigsby, Faizah Gillen, Jennifer Kimball, Craig McClay, Kim Powers, Galya Walt, Tracy Battaglia, Deborah Chassler, Linda Sprague Martinez, Karsten Lunze

“…This paper examines two CABs that are part of the HEALing Communities Study which aims to reduce overdose mortality. This analysis aimed to understand CAB members’ expectations, experiences, and perspectives on CAB structure, communication, facilitation, and effectiveness during the first year of an almost fully remote CAB implementation. …”
Get full text

Changes in the amount of nutrient of packaged foods and beverages after the initial implementation of the Chilean Law of Food Labelling and Advertising: A nonexperimental prospective study. by Marcela Reyes, Lindsey Smith Taillie, Barry Popkin, Rebecca Kanter, Stefanie Vandevijvere, Camila Corvalán

“…<h4>Background</h4>In June 2016, the first phase of the Chilean Food Labelling and Advertising Law that mandated front-of-package warning labels and marketing restrictions for unhealthy foods and beverages was implemented. We assess foods and beverages reformulation after this initial implementation.…”
Get full text

Nurse Manager’s Responsibilities in Creating Supportive Working Conditions Post Implementation of Everyday Coping: A Hermeneutic Research Study of District Nurses’ Experiences by Marianne Hauan, Kari Kvigne, Johanne Alteren

“…The nursing manager has a key role in supporting nurses and addressing challenges the nurses meet in their daily work, where everyday coping is implemented. The study highlights the importance for healthcare managers, at various levels in the healthcare sector, to be conscious of the district nursing practice, its complexity, and quality of health services when implementing change. …”
Get full text

Impact of pharmacist-prescriber partnerships to track antibiotic prescribing in publicly funded primary care in the Cape Town Metropole, South Africa: an implementation study by Prof Oliver Van Hecke, Dr Yusuf Adegoke, Prof Klaus von Pressentin, Prof Mosedi Namane, Prof Marc Mendelson, Prof Chris Butler, Prof Renier Coetzee

Get full text

Implementing and validating newborn screening for inborn errors of metabolism in South India: a 2-year observational study at a tertiary care hospital by Manju Hosuru Chikkalingaiah, Supriya Bevinakoppamath, Surajj S Archana, Aishwarya Kapa, Swetha N Kempegowda, Kusuma K Shivashankar, Shobha C Ramachandra, Suma K Basavarajaiah, Suma Nataraj, Akila Prashant

“…While routine in developed countries, NBS is not widely practised in India. This study aimed to implement NBS programme in a tertiary care hospital in South India and validate predetermined cut-off values tailored to the regional population.Methods Between 2020 and 2022, 5157 neonates were screened for congenital hypothyroidism (CH), congenital adrenal hyperplasia (CAH), cystic fibrosis (CF), glucose-6-phosphate dehydrogenase (G6PD) deficiency (G6PDD), phenylketonuria (PKU), galactosemia and biotinidase deficiency. …”
Get full text

Implementing and documenting cultural adaption of evidence-based practice strategies to reduce opioid overdose deaths: examples and lessons from the HEALing communities study by Erin B. Gibson, LaShawn Glasgow, Monica Nouvong, Margaret McGladrey, Darcy Freedman, Deborah Chassler, Rachel Vickers-Smith, Madeline D’Onfro, Dawn A. Goddard-Eckrich, Timothy Hunt, Avik Chatterjee, JaNae Holloway, Katie Fain, Rachel Sword Cruz, Linda Sprague Martinez

“…Methods The HEALing Communities Study engaged coalitions in 67 communities across four states to select and implement EBP strategies to reduce opioid overdose mortality. …”
Get full text

Pragmatic clustered randomised control trial to evaluate a self-regulated learning intervention to be implemented in South Australian primary schools—study protocol by S.A Brinkman, B. Lam, S. Dawson, R. Marrone, D. Schunk, K. Winkel, H. Hermes, F. Gabriel, S. Fowler, D. Engelhardt

“…A scalable, low-cost intervention targeted at grade 1 students (6–7 years old) in Germany was found to have substantial effects on impulse control and self-regulated learning, with sustained impacts on long-term academic success Schunk (Nat Hum Behav 6(12):1680-90, 2022). This study protocol seeks to adapt the Schunk et al. (2022) randomised trial to the Australian content and extend it to grades levels 2, 4 and 6. …”
Get full text

Protocol: A mixed-methods study to evaluate implementation and outcomes of U.S. state telemental health policy expansion during the COVID-19 pandemic. by Lucinda B Leung, Jasmeen J Santos, José J Escarce, Susan L Ettner, Claudia Der-Martirosian, Pushpa Raja, Alexander D McCourt, John Fortney, Emma E McGinty

“…Sizable variation in telemental health use by patient race-ethnicity, age, and rurality, and in its adoption across healthcare settings, underscores the need to study equitable dissemination and implementation of high-quality telemental health services in the real world. …”
Get full text

Maternal and perinatal outcomes after implementation of a more active management in late- and postterm pregnancies in Sweden: A population-based cohort study. by Karin Källén, Mikael Norman, Charlotte Elvander, Christina Bergh, Verena Sengpiel, Henrik Hagberg, Teresia Svanvik, Ulla-Britt Wennerholm

Get full text

Implementation of an Interdepartmental Collaborative Medication Review to Reduce Potentially Inappropriate Medication Use in Hospitalized Older Adults: Protocol for a Mixed Methods Study by Aravinda Kumar, Rajesh Kumar Konduru, Saranya Rajaram, Manikandan Mani, Anusha Natarajan, Jerin Jose Cherian, Bhavani Shankara Bagepally, Anil Jacob Purty, Nayyar Iqbal, Dineshbabu Sekar, Sudharsanan Sundaramurthi, Isabella Topno, Manjunatha Chalawadi Hanumappa

“…This study employs a multicentered mixed methods approach, combining qualitative methods (in-depth interviews and focus group discussions) to explore implementation challenges and quantitative analysis through a quasi-experimental study involving 280 hospitalized older adults. …”
Get full text

Development and usability testing of a preliminary web-based application for the clinical implementation of blood flow restriction: a mixed methods pilot study by Isaac J. Wedig, Isaac J. Wedig, Isaac J. Wedig, Erich J. Petushek, Erich J. Petushek, John J. Durocher, John McDaniel, Steven J. Elmer

“…However, several factors including medical screening, selection of equipment, and determination of cuff pressure still pose barriers for implementation. Accordingly, this study aimed to develop and test a web-based application to guide practitioners in using BFR safely and effectively.MethodsFirst, we developed an application to assist with medical screening, selection of appropriate equipment, and determination of cuff pressures. …”
Get full text

Realist Process Evaluation of the implementation and impact of an organisational cultural transformation programme in the Children and Young People's Secure Estate (CYPSE) in England: study protocol

“…This paper aims to present the protocol for a national cohort study examining the impact and implementation of this cultural transformation programme.Methods and analysis A mixed-methods realist evaluation will be conducted. …”
Get full text

Willingness to Implement Narrative Communication Interventions: Mixed Methods Study Among Breast Cancer Patients and Survivors at the University College Hospital, Ibadan, Nigeria by Oluwaponmile A. Odukoya MPH, Mojisola M. Oluwasanu PhD, Ndidi A. Okunnuga MD, Omobolaji Ayandipo MD, Susan Duncan MD, Oyedunni S. Arulogun PhD, Olufunmilayo I. Olopade MD, Atara Ntekim MD

“…Although narrative communication by patients or survivors is increasingly considered an effective approach for better breast cancer outcomes, there is limited information on its use in Nigeria. This study assessed the perception, willingness and generalized self-efficacy of breast cancer patients and survivors at the University College Hospital, Ibadan, to implement narrative communication interventions. …”
Get full text

Implementation of a large-scale hypertension program in primary health centres in the Federal Capital Territory, Nigeria: an explanatory, sequential mixed-methods study by Lisa R Hirschhorn, Mark D Huffman, Chisom Obiezu-Umeh, Namratha R Kandula, Oluwabunmi Ogungbe, Dike B Ojji, Erica L Jamro, Ikechukwu A Orji, Abigail S Baldridge, Nanna R Ripiye, Gabriel L Shedul, Blessing Akor, Chika Onwundinjo, Godiya Bwala, Rosemary C B Okoli

“…Introduction To optimise hypertension care cascade, the multilevel Hypertension Treatment in Nigeria (HTN) Program, adapted from the WHO HEARTS package, was implemented within 60 primary healthcare centres (PHCs) in the Federal Capital Territory, Nigeria, from January 2020 to December 2023.Methods We conducted an explanatory sequential mixed-methods study, guided by the RE-AIM QuEST (Reach, Effectiveness, Adoption, Implementation, and Maintenance - Qualitative Evaluation for Systematic Translation) framework, to examine the factors influencing reach, effectiveness, adoption, implementation, acceptability and maintenance of the program. …”
Get full text

Implementation of the OHS-interRAI for regular oral health assessments by non-dental caregivers: focus group study using a SWOT analysis by Patricia Ann Ivonne Vandenbulcke, Johanna de Almeida Mello, Florence Marleen Paulien Piccart, Jan De Lepeleire, Emilie Schoebrechts, Anja Declercq, Dominique Declerck, Joke Duyck

“…The optimised oral health section for use within the interRAI instruments, OHS-interRAI, empowers non-dental caregivers to monitor and address oral health issues. This qualitative study explores caregivers’ experiences with the OHS-interRAI to guide its further optimisation and implementation. …”
Get full text

Enhancing Clinical History Taking Through the Implementation of a Streamlined Electronic Questionnaire System at a Pediatric Headache Clinic: Development and Evaluation Study by Jaeso Cho, Ji Yeon Han, Anna Cho, Sooyoung Yoo, Ho-Young Lee, Hunmin Kim

“…A retrospective analysis compared clinical information acquired from patients aged <18 years visiting the pediatric neurology outpatient clinic for headaches, before and after implementing the BEST-Survey system. The study included 365 patients before and 452 patients after system implementation. …”
Get full text