Complementing but Not Replacing: Comparing the Impacts of GPT-4 and Native-Speaker Interaction on Chinese L2 Writing Outcomes by Zhaoyang Shan, Zhangyuan Song, Xu Jiang, Wen Chen, Luyao Chen

“…Interestingly, in the “interaction with GPT-4” condition, topic familiarity was positively correlated with better writing outcomes, whereas in the “interaction with a language partner” condition, perceived difficulty was positively correlated with content scores; however, content scores were negatively associated with writing confidence. This study suggests that LLMs should be used to complement and not replace human language partners in the L2 pre-writing phase.…”
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Complement factor H levels are decreased and correlated with serum C-reactive protein in late-onset Alzheimer's disease by Guo LU, Weihong LIU, Xinying HUANG, Yanxin ZHAO

“…The present study aimed to investigate clinical significance of human complement factor H (CFH) in patients with late-onset AD. …”
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Computer-Based Clinical Examination (CCE) in Surgery: Would It Complement or Replace the OSCE in the Post-COVID-19 Era? by Gamal E H A El Shallaly, Mudather M Bafadni, Hozifa M A Abdelmaged, Maysa H A Hamza

“…It saves time and is popular with the students and tutors. It complements the OSCE in the assessment of clinical competency and allows wide coverage of the curriculum. …”
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Criteria For Agreement When Conducting Local Consensus Discussions: A Qualitative Study by Pagano L, Long JC, Francis-Auton E, Hirschhorn A, Braithwaite J, Arnolda G, Sarkies MN

“…By clearly defining consensus types, organisations can strategically select consensus methods that best support decision-making and intervention implementation.Keywords: consensus-building, decision-making, implementation science, qualitative research, healthcare, perioperative pathways…”
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Adapting the WHO Safe Childbirth Checklist: A collaborative study in West Africa by Kadidiatou R. Kourouma, Tieba Millogo, Aissatou Diallo, Wambi M.E. Yaméogo, Marie L. Agbré-Yacé, Mamadou D. Baldé, Issaka Tiembré, Alexandre Delamou, Séni Kouanda

“…Aim: This study aimed to describe the WHO SCC adaptation process across Burkina Faso, Côte d’Ivoire, and Guinea, and the lessons learned. …”
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Acute depletion of complement C3 with cobra venom factor attenuates memory deficits induced by status epilepticus by Nicole D. Schartz, Yibo Li, Alexandra L. Sommer, Amy L. Brewster

“…Abstract Objective Status epilepticus (SE) significantly increases the risk for the development of unprovoked seizures, memory loss, and temporal lobe epilepsy. Our prior studies showed that SE increases complement C3 signaling in the hippocampus, which parallels memory deficits. …”
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Vers une définition des constructions « tough » en anglais : les adjectifs et leur complément infinitif by Joasha Boutault

“…This article focuses on the semantic and syntactic relations that the adjective entertains with its infinitival complement. Through the use of several syntactic tests and the study of genuine utterances in context, we propose a classification of « tough » constructions based on their semantico-syntactic properties. …”
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Bioactive Sphingolipids, Complement Cascade, and Free Hemoglobin Levels in Stable Coronary Artery Disease and Acute Myocardial Infarction by T. Jadczyk, K. Baranski, M. Syzdol, E. Nabialek, W. Wanha, R. Kurzelowski, M. Z. Ratajczak, M. Kucia, B. Dolegowska, M. Niewczas, J. Zejda, W. Wojakowski

“…Patients and Methods. The study enrolled 37 subjects (27 male) including 22 AMI patients, 7 CABG patients, and 8 healthy individuals as the control group (CTRL). …”
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Complement Activation is More Pronounced in the Kidneys of Critically Ill Patients With COVID-19 Than in Those With Bacterial Sepsis by Firas F. Alkaff, Grietje G. Talen, Marius C. van den Heuvel, Meint Volbeda, Matijs van Meurs, Jill Moser, Mohamed R. Daha, Jacob van den Born, Stefan P. Berger

“…Introduction: Previous studies have shown that the complement system plays an important role in COVID-19 acute kidney injury (AKI). …”
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Complement mediated signaling on pulmonary CD103(+) dendritic cells is critical for their migratory function in response to influenza infection. by Matheswaran Kandasamy, Poon C Ying, Adrian W S Ho, Hermi R Sumatoh, Andreas Schlitzer, Timothy R Hughes, David M Kemeny, B Paul Morgan, Florent Ginhoux, Baalasubramanian Sivasankar

“…However, little is known about the factors that regulate lung DC migration to the dLN. In this study, using a model of influenza infection, we demonstrate that complement component C3 is critically required for efficient emigration of DCs from the lung to the dLN. …”
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CYP4F18-Deficient Neutrophils Exhibit Increased Chemotaxis to Complement Component C5a by Rachel Vaivoda, Christine Vaine, Cassandra Boerstler, Kristy Galloway, Peter Christmas

“…There was no significant difference in the chemotactic response to LTB4, but the response to complement component C5a increased 1.9–2.25-fold in knockout cells compared to wild-type (P < 0.01). …”
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Complement opsonization of HIV-1 enhances the uptake by dendritic cells and involves the endocytic lectin and integrin receptor families. by Veronica Tjomsland, Rada Ellegård, Karlhans Che, Jorma Hinkula, Jeffrey D Lifson, Marie Larsson

“…Interaction with the complement system is an underappreciated aspect of HIV-1 infection; even in primary infection, complement fragments are found on virions with potential to affect the interplay between the virus and dendritic cells (DC). …”
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Randomized phase I trial outcomes show safe and sustainable inhibition of classical and lectin complement pathways by empasiprubart by Inge Van de Walle, Laura Bracke, Heidi Gytz Olesen, Tonke van Bragt, Stéphanie Cadour, Phillip De Decker, Giorgia Ciurlia, Erwin Pannecoucke, Emma K. Persson, Olivier Van de Steen, Xinghong Leng, Gregers Rom Andersen, Domenica Gandini, C. Erik Hack

“…Abstract Activation of classical and lectin complement pathways contributes to several human diseases. …”
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Complement C3 inhibitor in patients with paroxysmal nocturnal hemoglobinuria with suboptimal response to C5 inhibitor therapy by M. V. Marchenko, O. U. Klimova, E. V. Anikina, A. V. Lapina, T. A. Rudakova, T. I. Ksenzova, A. D. Kulagin

“…The introduction of the complement component C5 inhibitor eculizumab has radically changed the prognosis and quality of life of patients with paroxysmal nocturnal hemoglobinuria. …”
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Impact of preoperative complement-dependent cytotoxicity crossmatch on postoperative outcomes in kidney transplant recipients: A retrospective analysis by Chonghe Xu, Siqi Xie, Meiyi Lu, Wei Xu, Mei Zhu

“…Objectives The aim of the present study was to compare the differences in clinical outcomes within 6 months postoperatively between a complement-dependent cytotoxicity <10% group of low-risk kidney transplant patients and a complement-dependent cytotoxicity ≥10% group of relatively high-risk patients. …”
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Susceptibility to invasive meningococcal disease: polymorphism of complement system genes and Neisseria meningitidis factor H binding protein. by Declan T Bradley, Thomas W Bourke, Derek J Fairley, Raymond Borrow, Michael D Shields, Peter F Zipfel, Anne E Hughes

“…<h4>Background</h4>Neisseria meningitidis can cause severe infection in humans. Polymorphism of Complement Factor H (CFH) is associated with altered risk of invasive meningococcal disease (IMD). …”
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Visceral fat, cardiovascular risk factors and quality of life in lupus activity categorised via complement C3 by J Alfredo Martinez, Victor Moreno-Torres, María Martínez-Urbistondo, Raquel Castejón, Susana Mellor-Pita, Andrea Higuera-Gómez, Begoña de Cuevillas, Amanda Cuevas-Sierra, Juan-Antonio Vargas

“…Background Patients with lupus face increased cardiovascular risk linked to their autoimmune status. This study assesses the relationships between cardiovascular risk factors, lifestyle and health-related quality of life (HRQoL) concerning SLE activity categorised by complement C3.Methods 74 patients with SLE were recruited and stratified as active (C3 &lt;90 mg/dL) or inactive (C3 &gt;90 mg/dL), alongside 74 controls with obesity-related low-grade inflammation, at Hospital Universitario Puerta de Hierro Majadahonda. …”
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Dynamic Complement Protein Changes in Aqueous Humor and Plasma of Patients With Retinal Vein Occlusion During Ranibizumab Treatment by Guo T, Zhao Y, Liang S, Wang J, Liu H, Zhou Y, Xu H, Chen Z

“…Tingting Guo,1,2,&ast; Yanying Zhao,2,3,&ast; Shengnan Liang,2,3 Jie Wang,2 Hengwei Liu,2 Yufan Zhou,2 Heping Xu,3– 5 Zhongping Chen1– 3,6 1Aier Eye Hospital, Jinan University, Guangzhou, People’s Republic of China; 2Changsha Aier Eye Hospital, Changsha, People’s Republic of China; 3Aier Academy of Ophthalmology, Central South University, Changsha, People’s Republic of China; 4Aier Institute of Optometry and Vision Science, Aier Eye Hospital Group, Changsha, People’s Republic of China; 5The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, UK; 6School of Stomatology and Ophthalmology, Xianning Medical College, Xianning, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Zhongping Chen; Heping Xu, Email chenzhongping@csu.edu.cn; heping.xu@qub.ac.ukPurpose: To assess dynamic changes of complement protein in aqueous humor (AH) and plasma of retinal vein occlusion (RVO) patients during ranibizumab treatment, and to explore the differential expression of complement proteins in branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO).Patients and Methods: This prospective, consecutive case series study collected AH and plasma samples from 27 RVO patients at baseline, 1 and 2 months after ranibizumab treatment, including 19 BRVO and 8 CRVO patients. …”
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Complement Activation in Association with Markers of Neutrophil Extracellular Traps and Acute Myocardial Infarction in Stable Coronary Artery Disease by Karsten E. Kluge, Miriam S. Langseth, Trine B. Opstad, Alf Å. Pettersen, Harald Arnesen, Theis Tønnessen, Ingebjørg Seljeflot, Ragnhild Helseth

“…The aim of this study was to assess associations between complement activation and NETs in patients with stable CAD and examine the role of complement activation on clinical outcome. …”
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Astragalin-functionalized ultrasmall nanoparticles modulate the complement pathway to inhibit microglial synaptic phagocytosis for reducing anesthetic neurotoxicity by Gang Wang, Yaobao Han, Ke Peng, Zhilin Jiang, Tingting Wang, Qing Zheng, Wenting Li, Hanbing Xu, Fuhai Ji, Zhen Li

“…This study illustrates that CSPA NPs inhibit microglial synaptic elimination via the complement pathway, alleviating sevoflurane-induced neurotoxicity and providing insights into treating complement pathway-related diseases.…”
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