Activated Immune and Complement C3 Are Potential Contributors in MASH via Stimulating Neutrophil Extracellular Traps by Ao Liu, Xiaoling Deng, Shuhui Hou, Yuwen Xi, Keshu Xu

“…More attention has been paid to the relationship between immunity and MASLD. This study explored the roles of serum autoantibodies, immunoglobulins, and complements in MASLD. …”
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Effectiveness of Iptacopan Versus C5 Inhibitors in Complement Inhibitor‐Naive Patients With Paroxysmal Nocturnal Haemoglobinuria by Matthew Holt, Richard J. Kelly, Jilles M. Fermont, Soudeh Ansari, Marion Dahlke, Isabelle Brindel, Lynda Maafa, Flore Sicre deFontbrune, Régis Peffault deLatour

“…The single‐arm phase 3 APPOINT‐PNH trial (NCT04820530) investigating iptacopan monotherapy in complement inhibitor‐naive patients demonstrated significant haemoglobin concentration improvements. …”
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Participatory science to complement professional data: Towards conservation of declining native freshwater fish, the crucian carp by Kiran Thomas, Lukáš Kalous, Marek Brabec, Petr Velenský, Milan Gottwald, Daniel Bartoň, Sandip Tapkir, Yevdokiia Stepanyshyna, Zuzana Šmejkalová, Marek Šmejkal

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Systematic Review of the Link Between Oxford MEST-C Classification and Complement Activation in IgA Nephropathy by Gabriel Ștefan, Eric Alamartine, Christophe Mariat, Nicolas Maillard

“…We specifically selected studies that employed established methods to evaluate complement activation and the MEST-C classification. …”
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Phenoconversion of CYP3A4, CYP2C19 and CYP2D6 in Pediatrics, Adolescents and Young Adults With Lymphoma: Rationale and Design of the PEGASUS Study by Rachel Conyers, Tayla Stenta, Andrew A. Somogyi, Carl Kirkpatrick, Andreas Halman, Sophie Wang, Claire Moore, Dhrita Khatri, Elizabeth Williams, Roxanne Dyas, Tim Spelman, David A. Elliott, Amanda Gwee, Marliese Alexander

“…This prospective, single‐arm, single‐blind, nonrandomized feasibility study, will enroll individuals aged 6–25 years with a new diagnosis of Hodgkin Lymphoma or Non‐Hodgkin Lymphoma. …”
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Influence of Cow Dung Extract Complemented with Nutrient Solution on the Growth Performance of Lettuce (Lactuca sativa L) by Abu Raihan, Md. Jahedur Rahman, Chand Sultana Chandni, Sabina Yasmin, Md. Shahajahan Ali, M. Mokbul Hossain

“…Limited studies have focused on plant growth performance using organic-based solutions complemented with mineral elements in a hydroponic system. …”
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CT-based artificial intelligence system complementing deep learning model and radiologist for liver fibrosis staging by Shuang Zheng, Wenao Ma, Lin Mu, Kan He, Jianfeng Cao, Tiffany Y. So, Lei Zhang, Mingyang Li, Yanan Zhai, Feng Liu, Shunlin Guo, Longlin Yin, Liming Zhao, Lei Wang, Heather H.C. Lee, Wei Jiang, Junqi Niu, Pujun Gao, Qi Dou, Huimao Zhang

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Influenza-specific antibody-mediated and complement-dependent cellular cytotoxicity-inducing antibodies in vaccinated and infected pigs by Mithilesh Singh, Gabriela Mansano do Nascimento, Sankar Renu, Dina Bugybayeva, Olaitan C. Shekoni, Raksha Suresh, Jennifer Schrock, Sara Dolatyabi, Diego G. Diel, Prosper N. Boyaka, Gourapura J. Renukaradhya

“…In addition to neutralizing activity, antibodies can contribute to protection against viral infections through antibody-dependent cellular cytotoxicity (ADCC) and antibody-mediated complement-dependent cell cytotoxicity (CDC) mediated via Fcy receptors. …”
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Factor H-related 1 and heparan sulfate architecture contribute to complement dysregulation in C3 glomerulopathy by Amanda K. Slagle, Amanda K. Slagle, Nicolo Ghiringhelli Borsa, Kai Wang, Amanda O. Taylor, Nicole C. Meyer, Michael B. Jones, William D. Walls, Angela F. M. Nelson, Sarah M. Roberts, Mingyao Sun, Elena Goicoechea de Jorge, Santiago Rodriguez de Cordoba, Diana I. Jalal, Diana I. Jalal, Carla M. Nester, Yuzhou Zhang, Richard J. H. Smith, Richard J. H. Smith

“…Additionally, an in vitro C3b deposition assay was used to characterize the functional impact of FHR-1 on local complement activity.ResultsIn this study, we confirm that CFHR3-CFHR1 copy number impacts C3G risk. …”
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KLF4 overexpression protects against complement-mediated endothelial injury in transplant-associated thrombotic microangiopathy by Shuhui Jiang, Jiaqian Qi, Tingting Pan, Zhenzhen Yao, Siyi Lu, Yifei Han, Depei Wu, Yue Han

“…Although complement blockade benefits some patients, effective prophylactic and therapeutic strategies remain scarce. …”
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Assessing Patients with Chronic Pain Using the Basic Personality Inventory as a Complement to the Multidimensional Pain Inventory by Howard J Burton, Stephen A Kline, Robin Hargadon, Barry S Cooper, Roger D Shick, May C Ong-Lam

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Venom from Bothrops lanceolatus, a Snake Species Native to Martinique, Potently Activates the Complement System by Marie Delafontaine, Isadora Maria Villas-Boas, Giselle Pidde, Carmen W. van den Berg, Laurence Mathieu, Joël Blomet, Denise V. Tambourgi

“…Thus, further in vivo studies may support the idea that therapeutic management of systemic B. lanceolatus envenomation could include the use of Complement inhibitors as adjunct therapy.…”
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Moss-derived human complement factor H modulates retinal immune response and attenuates retinal degeneration by Mandy Hector, Verena Behnke, Paulina Dabrowska-Schlepp, Andreas Busch, Andreas Schaaf, Thomas Langmann, Anne Wolf

“…Genome-wide association studies in AMD patients and preclinical data have identified a dysregulated complement system and aberrant microglia responses in the pathogenesis of AMD. …”
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Levodopa / opicapone as a complement to STN-DBS in clinical practice. A retrospective single-centre analysis. by Moritz A. Loeffler, Philipp Klocke, Idil Cebi, Alireza Gharabaghi, Daniel Weiss

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The Constraints of The Teachers in The Implementation of 2013 Curriculum At SMP Negeri 1 Dullah, Maluku by Umar Rahaded, Hendro Widodo

“…Abstract: This study was aimed to describe the constraints of the teachers in the implementation of the 2013 curriculum. …”
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Providers' perceptions of implementing standardized postpartum family planning: a qualitative study of midwives and nurses in GhanaAJOG Global Reports at a Glance by Sarita Sonalkar, Ernest Maya, Chris Guure, Arden McAllister, Dzifa Adimle Puplampu, Roseline Dansowaa Doe, Mary Eluned Gaffield, James Kiarie

“…Study Design: We implemented the Postpartum Family Planning Package at three hospitals in Greater Accra and Eastern Regions, Ghana. …”
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Context, mechanisms and community engagement in implementation strategies: a systematic review protocol of implementation strategies designed using implementation mapping by Eunyoung Kang, Maria E Fernández, Serena Rodriguez, Gill ten Hoor, Derek W Craig, Jennifer Stockton

“…Introduction Implementation Mapping (IM) has increasingly been used for the design and/or selection and tailoring implementation strategies to promote the effective translation of evidence-based interventions into practice. …”
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Implementing a behaviour change communication interaction for enhancing male involvement in maternity care among the Saharia Tribes in Gwalior District, Madhya Pradesh: a feasibility study by Tulsi Adhikari, Saritha Nair, Ashpinder kaur Grover

“…Result Acceptability testing study reveal that BCC intervention was successfully accepted by intended individual- both targeted individuals and those involved in implementing programs. …”
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Creating system-wide change in medicine: The role of implementation science in achieving scale and adoption by Simon Barry, Chris Davies

“…Delivering meaningful change in healthcare is less about new discoveries and more about ensuring adoption at scale of what is already known to work. Implementation science (IS) studies the methods that support systematic uptake of evidence-based practices into routine care. …”
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Integrating silver diamine fluoride into school-based oral health programs: A pilot study by Carrie Godes, Lisa Westhoff, Tamarinda Barry Godín, Ryan Richard Ruff

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