FACTORS INITIATING IMPLEMENTATION OF INNOVATION AND BARRIERS IN THEIR IMPLEMENTATION ON THE EXAMPLE OF ENTERPRISES IN PODKARPACKIE by Stanisław ZAJĄC, Dorota JANAS

“…The aim of the study was to assess innovation in enterprises in the province of Podkarpackie. …”
Get full text

Implementation of the Meningitis Vaccine Project in Africa: lessons for vaccine implementation programs by Obidimma Ezezika, Meron Mengistu, Thomas Lear

“…To bridge gaps upstream of vaccine administration and in understanding the project's planning, delivery and outcomes, the primary objective of this study was to delineate the barriers to and facilitators of sustainable implementation in an upstream context of the delivery of the MenAfriVac vaccine and to draw critical lessons for other vaccination programs…”
Get full text

Implementation of the Deposit System in Poland as a Tool for Implementing the Circular Economy by Andrzej Zarębski, Joanna Zarębska, Konrad Marosek

“…Currently, work is still underway to implement this system starting in January 2025. The aim of the study is to describe the current work of the ministry, entrepreneurs and recovery organizations in this area and, on this basis, to indicate the barriers and uncertainties encountered in the implementation of this system. …”
Get full text

Tempering implementation optimism: distinguishing between efficacy and effectiveness in implementation research by Per Nilsen, Jeanette Wassar Kirk, Katarina Ulfsdotter Gunnarsson, Kristin Thomas

“…Yet despite its importance, this distinction is rarely made explicit in implementation studies. Research often fails to specify the conditions under which implementation strategies are investigated; studies can vary widely in how closely they reflect routine practice. …”
Get full text

Miltefosine implementation for treatment of cutaneous leishmaniasis: access indicators in the state of Minas Gerais, 2021-2024 by Sarah Nascimento Silva, Mell Ferreira Saliba, Laís Raquel Ribeiro, Gláucia Cota

Subjects: Get full text

Hospital discharge planning in cardiac care: study protocol for a mixed-methods study on the implementation, influencing factors and quality of care in Germany by Udo Schneider, Gabriele Meyer, Dirk Horenkamp-Sonntag, Vera Winter, Kai Svane Blume, Steffen Fleischer, Raphaele Bartels, Lena Imhof, Karl Blum, Susan Gottschalk, Robin Heber, Bjoern Andrew Remppis, Jonas Schreyoegg

“…Although DP has been legally required for all hospitals in Germany since 2017, several studies show considerable variation in its implementation, likely due to differences in structural characteristics and organisational processes. …”
Get full text

Identification of FANCG as a prognostic factor for prostate cancer by Wenlong Gao, Peng Liu, Han Xinyue, Yuanjie Niu, Wu Yi

“…Abstract Background To ascertain role of the fanconi anemia complementation group G (FANCG) gene in prostate cancer (PCa) and the suitability of the FANCG gene as a prognostic biomarker for PCa. …”
Get full text

Watershed-scale dispersal patterns of juvenile Chinook Salmon (Oncorhynchus tshawytscha) revealed through genetic parentage analysis by Matthew J. Kaylor, Lindsy R. Ciepiela, Melody Feden, Joseph T. Lemanski, Casey Justice, Benjamin A. Staton, Jonathan B. Armstrong, Stefan Kelly, Shawn R. Narum, Ian A. Tattam, Seth M. White

Get full text

Narrow Band Imaging complements Eosinophilic Esophagitis Reference Score in predicting inflammatory infiltration in patients with dysphagia by Kotryna Truskaite, Laura Vossen Engblom, Greger Lindberg, Aldona Dlugosz

Get full text

Differential dependencies of monocytes and neutrophils on dectin-1, dectin-2 and complement for the recognition of fungal particles in inflammation. by Jacqueline U McDonald, Marcela Rosas, Gordon D Brown, Simon A Jones, Philip R Taylor

“…Collectively these roles are consistent with previously described roles of dectin-1 and dectin-2 in driving inflammatory and adaptive immune responses and complement in containing fungal burdens. This study emphasizes the importance of heterogeneity of receptor expression across myeloid cell subsets in protective immune responses.…”
Get full text

Estimation of Complement Components (C3 and C4) and hs-CRP Level in Kidney Failure Patients by Zaid N. Elia, Nisreen W. Mustafa

“…This study was aimed to detect the level of complement system in kidney failure patients. …”
Get full text

Classical Complement (CH 50 ) activity among children with some bacterial and parasitic infections in Sokoto, Nigeria by Kalgo, M.U.* , Muhammad, T.B. , Yeldu, M.H. , Garba, B.I. , Hamid, K.M. , Isiyaku, A. , Raji, H.Y. , Bello, M. , Bunza, N.M. Garba, M.R.

“…Further studies are hereby suggested to explore the various mechanisms of complement CH 50 activity in the defense against microbial infections.…”
Get full text

The role of complement C1q in atrial fibrillation: a marker for disease progression and surgical outcomes by Yuefeng Ju, MaoJing Wang, Yang Ji, Zhihui Wang, Wenzhuo Wang, Feiyue Liu, Qing Zhao

“…C1q, a key initiator of the classical pathway, is closely associated with various chronic inflammatory conditions. This observational study aims to elucidate the potential risk relationship between serum complement C1q levels and atrial fibrillation (AF).Materials and methodsThis retrospective cohort study included 812 AF patients treated at the Affiliated Hospital of Qingdao University from January 2020 to October 2022, comprising 694 patients in the paroxysmal AF group and 118 in the persistent AF group. …”
Get full text

Plasma complement proteins as biomarkers and therapeutic targets in chronic kidney disease: a Mendelian randomization analysis by Yu-Peng Xu, Zheng-Qi Song, Ming-Li Chen, Yang-Li Fang, Hui-Di Zhang

“…CD55, C6, CR2, CFHR2, CFD were also correlated with renal function indicators, highlighting the role of complement proteins in CKD.Conclusion This study supports plasma complement proteins as potential biomarkers and therapeutic targets for CKD. …”
Get full text

Target complement factor H / serum amyloid a signaling in trichloroethylene-induced immune kidney injury by Haibo Xie, Bo Liang, Jingyi Zhao, Chen You, Qirui Bai, Rui Li, Jian Chen, Pengcheng Zhou, Luolun Dong, Ruixuan Cheng, Jiaxiang Zhang, Qixing Zhu

“…However, the specific role of complement factor H (CFH) in this context remains unclear. …”
Get full text

An RNase H‐Like gene complements resistance to Bean common mosaic necrosis virus in Phaseolus vulgaris by Alvaro Soler‐Garzón, Phillip N. Miklas

Get full text

Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective by Didar Murad, Rehan Zafar Paracha, Maryum Nisar

“…Additionally, the regulation of C5b-9 could aid in lysing the virus and/or infected cells. In conclusion, this study explains the regulatory mechanisms of the hemostatic and complement systems and illustrates how the biopathway machinery sustains the balance between activation and inhibition. …”
Get full text

Gut microbial dysbiosis activates the classical complement pathway in a short-term morphine treatment model by Nicolas Vitari, Richa Jalodia, Junyi Tao, Udhghatri Kolli, Salma Singh, Lily V. Rodriguez, Umakant Sharma, Sabita Roy

“…Antibodies play an essential role in preserving intestinal homeostasis in healthy and dysbiotic states. Recent studies demonstrate that a microbiome-dependent intestine-specific complement system maintains intestinal homeostasis. …”
Get full text

Genotypic and phenotypic diversity of Lactobacillus rhamnosus clinical isolates, their comparison with strain GG and their recognition by complement system. by Eija Nissilä, François P Douillard, Jarmo Ritari, Lars Paulin, Hanna M Järvinen, Pia Rasinkangas, Karita Haapasalo, Seppo Meri, Hanna Jarva, Willem M de Vos

“…The capacity of the L. rhamnosus strains to activate serum complement was studied using immunological assays for complement factor C3a and the terminal pathway complement complex (TCC). …”
Get full text

Supramaximal high-intensity interval training for older adults in a community setting: a pragmatic feasibility study by Erik Frykholm, Beatrice Pettersson, Mattias Hedlund, Maria Wiklund, Bengt Johansson, Carl-Johan Boraxbekk, Erik Rosendahl, Nina Lindelöf

“…These insights help refine and optimize supramaximal HIT implementation for older adults in community settings. …”
Get full text