Indoor residual spraying uptake and its effect on malaria morbidity in Ngoma district, Eastern province of Rwanda, 2018–2021 by Olivier Nsekuye, Samuel S. Malamba, Jared Omolo, Ziad El-Khatib, Jean-Louis N. Mangara, Dunia Munyakanage, Angela Umutoni, Naomi W. Lucchi, Edson Rwagasore, Samuel Rwunganira, Aline Uwimana, Daniel Ntabanganyimana, Jean-Claude Niyoyita, Henri Desire Uwayo, Theoneste Ntakirutimana

“…Abstract Background Indoor residual spraying (IRS) has been implemented in Rwanda in districts with high malaria transmission, including Ngoma District. …”
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Community engagement and chronic viral hepatitis public health interventions: a systematic review, meta-analysis, and complementary crowdsourcing open callResearch in context by Yifan Li, Eneyi Kpokiri, Dalia Elasi, Rongrong Sheng, Keying Wang, Hayley Conyers, Ye Zhang, Danjuma K. Adda, Philippa C. Matthews, Thomas Fitzpatrick, Joseph D. Tucker, Dan Wu

“…Interpretation: Findings underscored the importance of community engagement in chronic viral hepatitis service delivery across the care continuum. Implementing community-engaged interventions can enhance chronic viral hepatitis elimination efforts. …”
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Multi-physics ensemble modelling of Arctic tundra snowpack properties by G. J. Woolley, N. Rutter, L. Wake, V. Vionnet, C. Derksen, R. Essery, P. Marsh, R. Tutton, B. Walker, M. Lafaysse, D. Pritchard

“…To improve the simulation of profiles of density and SSA, parameterisations of snow physical processes that consider the effect of high wind speeds, the presence of basal vegetation, and alternate thermal conductivity formulations were implemented into an ensemble version of the Soil, Vegetation, and Snow version 2 (SVS2-Crocus) land surface model, creating Arctic SVS2-Crocus. …”
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Earth's future climate and its variability simulated at 9 km global resolution by J.-Y. Moon, J.-Y. Moon, J. Streffing, J. Streffing, J. Streffing, S.-S. Lee, S.-S. Lee, T. Semmler, T. Semmler, M. Andrés-Martínez, M. Andrés-Martínez, J. Chen, E.-B. Cho, E.-B. Cho, J.-E. Chu, C. L. E. Franzke, C. L. E. Franzke, J. P. Gärtner, R. Ghosh, J. Hegewald, J. Hegewald, S. Hong, D.-W. Kim, D.-W. Kim, N. Koldunov, J.-Y. Lee, J.-Y. Lee, Z. Lin, C. Liu, S. N. Loza, W. Park, W. Park, W. Roh, W. Roh, D. V. Sein, D. V. Sein, D. V. Sein, S. Sharma, S. Sharma, D. Sidorenko, J.-H. Son, J.-H. Son, J.-H. Son, M. F. Stuecker, Q. Wang, G. Yi, G. Yi, M. Zapponini, T. Jung, T. Jung, A. Timmermann, A. Timmermann

“…To assess climate risks on regional scales and implement adaptation measures, policymakers and stakeholders often require climate change information on scales that are considerably smaller than the typical resolution of global climate models (<span class="inline-formula"><i>O</i></span>(100 km)). …”
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Epidemic trend of Salmonella from swines and broilers in China from 2014 to 2023 and genetic evolution analysis of ESBLs-producing strains by Yaopeng Liu, Yaopeng Liu, Lin Wang, Juan Wang, Mingzhe Lu, Na Liu, Jianmei Zhao, Fangyuan Hu, Fangyuan Hu, Keguang Han, Junhui Liu, Junwei Wang, Zhina Qu

“…Whole genome sequencing analysis revealed that 36 swine-derived ESBL-producing Salmonella strains contained 6 ST-types and 13 cgST-types, among which ST34 and ST17 were dominant ST-types; a total of 35 resistance genes across 11 classes, blaCTX-M-14, blaTEM-1B, and blaCTX-M-65 were the predominant subtypes of β-lactam resistance genes. 126 broiler-derived ESBL-producing Salmonella strains included 19 ST-types and 37 cgST-types, with ST17 and ST198 as the dominant ST-types; a total of 52 resistance genes belonging to 12 classes, blaCTX-M-55, blaCTX-M-65, blaTEM-1B, and blaOXA-1 identified as the major subtypes of β-lactam resistance genes.DiscussionThis suggests that we should thoroughly implement management policies aimed at reducing the use of veterinary antimicrobials. …”
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Clinical Outcomes of a Novel Multidisciplinary Care Program in Advanced Kidney Disease (PEAK) by Daniil Shimonov, Sri Lekha Tummalapalli, Stephanie Donahue, Vidya Narayana, Sylvia Wu, Lisa S. Walters, Roberta Billman, Barbara Desiderio, Sandra Pressman, Oliver Fielding, Kariel Sweeney, Daniel Cukor, Daniel M. Levine, Thomas S. Parker, Vesh Srivatana, Jeffrey Silberzweig, Frank Liu, Andrew Bohmart

“…Introduction: Multidisciplinary care (MDC) for late-stage chronic kidney disease (CKD) has been associated with improved patient outcomes compared with traditional nephrology care; however, the optimal MDC model is unknown. In 2015, we implemented a novel MDC model for patients with late-stage CKD informed by the Chronic Care Model conceptual framework, including an expanded MDC team, care plan meetings, clinical risk prediction, and a patient dashboard. …”
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Pulmonary arterial hypertension in systemic lupus erythematosus: identification of risk factors and haemodynamics characteristics in a multicentre retrospective cohort by Carlo Alberto Scirè, Alessandra Bortoluzzi, Micaela Fredi, Matthias Schneider, Veronica Codullo, Carlomaurizio Montecucco, Alain Meyer, Ilaria Cavazzana, Lorenzo Cavagna, Franco Franceschini, Andreas Schwarting, Konstantinos Triantafyllias, Gamal Chehab, Christina Düsing, Jutta Richter, Ettore Silvagni, Oliver Sander, Giovanni Zanframundo, Claudia Bracaglia, Matthieu Canuet, Stefano Ghio, Rebecca Fischer, Emiliano Marasco, Sezgin Sahin, Lisa Keller, Marianne Riou, Stefanie Keymel

“…The variables we identified could be used to implement a screening algorithm to identify patients with SLE at risk of developing PAH.…”
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Embedding electronic patient-reported outcome measures into routine care for patients with stage III MELanoma (ePROMs-MEL): protocol for a prospective, longitudinal, mixed-methods... by Serigne Lo, Andrew Spillane, Donna Milne, Robyn Saw, Mbathio Dieng, Iris Bartula, Rachael Morton, Frances Boyle, Julia Lai-Kwon, Kathy Dempsey, Craig Lawn, Thomas Pennington, Skye Dong, Linda Seaman, Dina Saks, Jake Robert Thompson

“…The aim of this study is to evaluate the feasibility and acceptability of implementing electronic PROMs (ePROMs) into routine care from the perspectives of patients with stage III melanoma and their treating clinical team.Methods and analysis A minimum of 50 patients and 5 clinicians will be recruited to this prospective, longitudinal pilot study (ePROMs-MELanoma). …”
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Profiling the needs of dementia caregivers in a Brazilian cross‐sectional study by Alan Cronemberger Andrade, Mariel Carolina Montiel‐Aponte, Ronaldo Cristiano Prati, Sheilla de Medeiros Correia Marin, Emanuela Bezerra Torres Mattos, Flavio Shigeo Yamamoto, Marcia Maria Pires Camargo Novelli, Walter Teixeira Lima Junior

“…A substantial proportion left their jobs to fulfill caregiving duties, underscoring the urgency of implementing policies that address the extensive needs of individuals with dementia and their caregivers. …”
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Willingness to participate in combined breast and cervical cancer screening and its influencing factors among 35 - 64 year old women participating in screening in Jinan city, 2024:... by Hongsheng SONG, Zeyun ZHAO, Cuiyu GONG, Fei ZHU, Xuelian ZHAO, Li ZHANG, Fanghui ZHAO, Yuping WANG

“…Further research is needed to assess the feasibility of implementing this model in different regional settings.…”
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Neck pain burden in China and G20 countries: an analysis of 1990–2021 with a 30-year forecast for China by Huale Li, Huale Li, Zhichun Chang, Zhichun Chang, Ting Qin, Ting Qin, Yanfang Li, Yanfang Li, Mingren Hu, Xinjing Yang, Jun Li, Jun Li, Yufeng Xie, Yufeng Xie

“…Policies should balance technological innovation with social support, strengthen legislative protection for high-risk occupations and harsh climates, implement personalized interventions, and reduce the burden at its root.…”
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Detecting Clinically Significant Prostate Cancer in PI-RADS 3 Lesions Using T2w-Derived Radiomics Feature Maps in 3T Prostate MRI by Laura J. Jensen, Damon Kim, Thomas Elgeti, Ingo G. Steffen, Lars-Arne Schaafs, Matthias Haas, Lukas J. Kurz, Bernd Hamm, Sebastian N. Nagel

“…Univariate models for single feature performance and bivariate models implementing PSA density (PSAD) were calculated. Ten map-derived features differed significantly between the csPCa and non-csPCa groups (AUCs: 0.70–0.84). …”
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Principles, barriers and enablers to agroecological animal production systems: a qualitative approach based on five case studies by B. Dumont, C. Barlagne, P. Cassart, J.E. Duval, A. Fanchone, J-L. Gourdine, O. Huguenin-Elie, Y. Kazakova, J. Klötzli, A. Lüscher, E. Oteros-Rozas, D. Pomies, M.G. Rivera Ferre, W.A.H. Rossing, V. Stefanova, A. Swartebroeckx, C. Zagaria

“…Long-term commitment from local practitioners is required so that co-designed solutions are implemented, which can strengthen the economic and social viability of animal production areas.…”
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Longitudinal phenotypic and genomic evidence revealing increased risk of drug resistance accumulation in tuberculosis patients in the counties of central China by Fu-Lin Wang, Rong Chen, Qiao Xu, Xiao-Qin Wang, Feng-Xi Tao, Zi-Kang Huang, You-Tong Zhang, Shu-Qiong Chen, Xue-Jing Wu, Hong-Yuan Cao, Qi Jiang

“…Urgent action is needed to decentralize rapid resistance screening and implement tiered care models in primary clinics to curb transmission and mitigate the expanding DR-TB threat.IMPORTANCEThe ongoing epidemic of drug-resistant tuberculosis (DR-TB) in resource-poor settings poses a major public health challenge. …”
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Optimized intelligent learning for groundwater quality prediction in diverse aquifers of arid and semi-arid regions of India by Imran Khan, Sarwar Nizam, Apoorva Bamal, Abdul Majed Sajib, Mir Talas Mahammad Diganta, Mohd Azfar Shaida, S.M. Ashekuzzaman, Stephen Nash, Agnieszka I. Olbert, Md Galal Uddin

“…Ensuring access to safe, affordable drinking water while implementing sustainable management practices is vital for achieving the United Nations Sustainable Development Goals-2030. …”
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A comparative analysis of cluster based interventions on healthcare-associated infections in a tertiary care hospital in China by Ya Zou, Chuyu Lao, Ting Fan, Tian Wang, Guanwen Lin, Cuiqiong Fan, Yisui Cen, Yukun Lin, Miao Yang, Congrong Li, Zihuan Li

“…This study analyzes the trend of incidence of HAIs in a tertiary care hospital in China and assesses the effectiveness of cluster based interventions.MethodsA retrospective analysis was conducted on HAIs reports from 2015 to 2024, focusing on episodes involving the incidence rate of hospital infections, the catheter infection rate related to invasive procedures in the intensive care unit (ICU), healthcare workers’ compliance with hand hygiene, needlestick and sharp injuries (NSIs) among healthcare workers, the prophylactic use rate of antimicrobial agents for Class I surgical incisions, and the antimicrobial usage density (AUD). In 2019, we implemented cluster-based interventions on the incidence of HAIs, strengthening hospital infection control.ResultsThe downward trend in HAIs is notable, with infection rates of 9.34 ± 0.25 and 7.29 ± 0.78 per 1,000 patient-days observed during the periods of 2015–2019 and 2020–2024, respectively (p &lt; 0.001). …”
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Assessing patients’ experience of care in four referral hospitals: a cross-sectional survey of outpatients in two South African rural provinces by Wezile W. Chitha, Onke R. Mnyaka, Akhona Ncinitwa, Olona Giwu, Teboho Mashao, Kuhle Mabophe, Sibusiso C. Nomatshila, Itumeleng Funani, Vivien Essel, Xolelwa Ntlongweni, Kedibone Maake, Nomfuneko Sithole, Ntiyiso Khosa, Maphoko Masemola, Ziyanda Ngcobo, Murendeni Mulamu, Bongiwe Mkabela, Siyabonga Sibulawa, Buyiswa Swartbooi, Godfrey Mokobane, Sikhumbuzo A. Mabunda

“…Conclusions Whilst hospitals have been implementing various quality measures to improve patient’s experience of care, there are a few concerns such as non-availability of drinking water, lack of knowledge of complaints processes and waiting times that were mostly reported to be unacceptable. …”
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Psychological interventions mitigated occupational stress in high-risk workers in Shenzhen, China by Naixing Zhang, Wei Zhou, Aipin Xiao, Shaofan Weng, Liuzhuo Zhang, Dexiang Zhu, Jinlin Wang, Ling Nian, Dafeng Lin, Dafeng Lin

“…This study investigated occupational stress among the potential high-risk workers in Shenzhen, China, and evaluated the psychological interventions subsequently implemented.MethodsA stratified cluster sampling method was employed, randomly selecting one quarter of clusters (clustered by work unit) from each of the four strata (stratified by occupational category) including firefighters, bus drivers, video display terminal (VDT) operators, and port workers, respectively, as the study cohort. …”
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Machine learning and molecular docking prediction of potential inhibitors against dengue virus by George Hanson, Joseph Adams, Daveson I. B. Kepgang, Luke S. Zondagh, Lewis Tem Bueh, Andy Asante, Soham A. Shirolkar, Maureen Kisaakye, Hem Bondarwad, Olaitan I. Awe

“…The detailed interactions, toxicity, stability, and conformational changes of selected compounds were assessed through protein-ligand interaction studies, molecular dynamics (MD) simulations, and binding free energy calculations.ResultsWe implemented a robust three-dataset splitting strategy, employing the Logistic Regression algorithm, which achieved an accuracy of 94%. …”
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School-based physical activity and health-related fitness in Mediterranean students: findings from the DELICIOUS project by Mohamed Aly, Achraf Ammar, Achraf Ammar, Achraf Ammar, Khaled Trabelsi, Khaled Trabelsi, Khaled Trabelsi, Liwa Masmoudi, Noha El-Gyar, Amira M. Shalaby, Osama Abdelkarim

“…These findings highlight the need for tailored, school-based PA programs that consider baseline fitness levels and regional factors. Implementing such interventions could play a crucial role in addressing physical inactivity and fostering long-term health benefits in children.…”
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