Complement factor H in molecular regulation of angiogenesis by Li Jiang, Wang Kaili, Starodubtseva Maria N., Nadyrov Eldar, Kapron Carolyn M., Hoh Josephine, Liu Ju

Get full text

Initiation and Regulation of Complement during Hemolytic Transfusion Reactions by Sean R. Stowell, Anne M. Winkler, Cheryl L. Maier, C. Maridith Arthur, Nicole H. Smith, Kathryn R. Girard-Pierce, Richard D. Cummings, James C. Zimring, Jeanne E. Hendrickson

“…In this paper we will focus on the role of complement in initiating and regulating hemolytic transfusion reactions and will discuss potential strategies aimed at mitigating or favorably modulating complement during incompatible red blood cell transfusions.…”
Get full text

Regulation of anti-microbial autophagy by factors of the complement system by Christophe Viret, Aurore Rozières, Rémi Duclaux-Loras, Gilles Boschetti, Stéphane Nancey, Mathias Faure

“…The system is highly efficient and is therefore finely regulated. In addition to these well-established properties, recent works have revealed that components of the complement system can be involved in a variety of other functions including in autophagy, the conserved mechanism that allows for the targeting and degradation of cytosolic materials by the lysosomal pathway after confining them into specialized organelles called autophagosomes. …”
Get full text

Borrelia burgdorferi complement regulator-acquiring surface protein 2 does not contribute to complement resistance or host infectivity. by Adam S Coleman, Xiuli Yang, Manish Kumar, Xinyue Zhang, Kamoltip Promnares, Deborah Shroder, Melisha R Kenedy, John F Anderson, Darrin R Akins, Utpal Pal

“…Borrelia burgdorferi, the pathogen of Lyme disease, cycles in nature through Ixodes ticks and mammalian hosts. At least five Complement Regulator-Acquiring Surface Proteins (BbCRASPs) are produced by B. burgdorferi, which are thought to assist spirochetes in host immune evasion. …”
Get full text

Contribution of the Infection-Associated Complement Regulator-Acquiring Surface Protein 4 (ErpC) to Complement Resistance of Borrelia burgdorferi by Claudia Hammerschmidt, Teresia Hallström, Christine Skerka, Reinhard Wallich, Brian Stevenson, Peter F. Zipfel, Peter Kraiczy

“…Borrelia burgdorferi evades complement-mediated killing by interacting with complement regulators through distinct complement regulator-acquiring surface proteins (CRASPs). …”
Get full text

Current landscape of paroxysmal nocturnal hemoglobinuria in the era of complement inhibitors and regulators by Julia J. Shi, Yusuf M. Ozcan, Carlos I. Ayala Santos, Hetalkumari Patel, Jamile Shammo, Taha Bat

Get full text

Proteomic and In Silico Analyses Highlight Complement System’s Role in Bladder Cancer Immune Regulation by Tuğcan Korak, İbrahim Halil Baloğlu, Murat Kasap, Elif Damla Arisan, Gurler Akpinar, Serdar Arisan

“…<i>Conclusions</i>: This study highlights the pivotal role of the complement system in the immune regulation of BLCA. …”
Get full text

Challenges in implementing the public property regulations in Serbia by Nikolić Ljubica

Subjects: Get full text

Genetic variants in complement-related genes: potential implications for cancer risk and progression by Jenny N. Fung, Ruben Pio

Subjects: “…Complement system…”
Get full text

Candidiasis: Insights into Virulence Factors, Complement Evasion and Antifungal Drug Resistance by Nidaa Riaz Gaffar, Nisha Valand, Umakhanth Venkatraman Girija

Subjects: Get full text

How do banks implement the capital regulation requirement? by Ho Thanh Tung, Jaroslav Belás, Tatyana Baideldinova

Get full text

Structural analysis of the C-terminal region (modules 18-20) of complement regulator factor H (FH). by Hugh P Morgan, Haydyn D T Mertens, Mara Guariento, Christoph Q Schmidt, Dinesh C Soares, Dmitri I Svergun, Andrew P Herbert, Paul N Barlow, Jonathan P Hannan

“…Factor H (FH) is a soluble regulator of the human complement system affording protection to host tissues. …”
Get full text

Leptospira interrogans endostatin-like outer membrane proteins bind host fibronectin, laminin and regulators of complement. by Brian Stevenson, Henry A Choy, Marija Pinne, Matthew L Rotondi, M Clarke Miller, Edward Demoll, Peter Kraiczy, Anne E Cooley, Trevor P Creamer, Marc A Suchard, Catherine A Brissette, Ashutosh Verma, David A Haake

“…The LenA outer surface protein (formerly called LfhA and Lsa24) was previously shown to bind the host ECM component laminin and the complement regulators factor H and factor H-related protein-1. …”
Get full text

AI at Risk in the EU: It’s Not Regulation, It’s Implementation by Judith Arnal

“…The implementation of the General Data Protection Regulation (GDPR) in the EU, rather than the regulation itself, is holding back technological innovation. …”
Get full text

FUNCTIONS OF SELF-REGULATING ORGANIZATIONS: CONTENT AND PROBLEMS OF IMPLEMENTATION by A. Algazina

“…The article is devoted to the description of the basic functions of self-regulating organizations: regulatory, control, organizational and security, jurisdictional.The purpose of the article is to explore the content features of self-regulating organizations, to identify problems in their implementation and offer recommendations for their solution.Methodology. …”
Get full text

Earth observation as enabler for implementing the EU regulation on deforestation-free products by Katja Berger, Martin Herold, Zoltan Szantoi

Get full text

THE PROBLEMS OF IMPLEMENTATION AND REGULATION OF LAND MARKET IN THE AGRICULTURAL SECTOR OF UKRAINE by Anatoliy SHVORAK, Dmytro FILIUK, Nataliia KORETSKA, Nataliya VAHNOVSKA, Iryna BRODSKA, Alla TENDYUK

Get full text

Perceptions of the implementation of credit rating agency regulation in South Africa by David Rabinowitz, Mahmood I. Surty, Waheeda Mohamed, Warren Maroun

“…Background: Credit rating agencies (CRA) played a key role in the global financial crises of 2007/2008 which led to the introduction of CRA regulation. Aim: Using Giddens’ theory of modernity as a framework, this article analyses experts’ perceptions of the implementation of the CRA regulation in South Africa. …”
Get full text

Lean Regulation in Public Administration: Preconditions for Implementation and Main Content by I. I. Rakhmeeva, M. Yu. Andronov

“…The research addressed several tasks, including a methodological comparison of approaches to collective regulation; defining the concept of lean regulation; and describing the effects of its implementation in public administration, with a focus on organizations in the financial sector. …”
Get full text

Sharia Economic Law Regulation In Indonesia And Malaysia: Implementation And Challenges by Umi Khusnul Khotimah

“…Introduction: This article explores the implementation and regulatory challenges of Sharia economic law in Indonesia and Malaysia, two key players in Islamic finance. …”
Get full text