From biomarker to targeted therapy: investigating trophoblast cell-surface antigen 2 expression in triple-negative breast cancer– insights from the national cancer institute by Noura A. A. Ebrahim, Mustafa A. Hussein, Mohamed Emam Sobeih, Nancy H. Amin

“…The results endorse the use of TROP-2 expression levels for patient categorization, thereby advancing the implementation of personalized treatment strategies and accelerating the progression towards precision oncology.…”
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Traditionally used phytomedicines and their associated threats in Bita district, southwestern Ethiopia by Ashebir Awoke, Girma Gudesho, Kindu Chane, Yared Siyum, Walle Tilahun, Habtamu Gebremedhin, Afework Tadesse

“…The research utilized several quantitative methodologies, including the informant consensus factor (ICF), fidelity level (FL), plant part value, preference ranking, and direct matrix ranking. …”
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Endorsement of reporting guidelines and clinical trial registration across urological medical journals: a cross-sectional study by Alex Hagood, Joseph Case, Trevor Magee, Caleb Smith, Danya Nees, Griffin Hughes, Matt Vassar

“…Future efforts should focus on evaluating the implementation of these policies and identifying barriers that hinder their adoption.…”
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Association of plasma neurofilament light protein concentration with sleep disturbance after intracerebral hemorrhage by Peng Xu, Jinlei Yang, Xin Zhao, Fang Liu, Qiang Liu, Handong Wang

“…Elevated levels of NfL at admission are associated with poorer prognoses and increased sleep-related issues, indicating that monitoring pNfL could be valuable for prognostication and the implementation of targeted interventions.…”
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Role of the amygdala opioid system in the effects of stress on the post-learning sleep patterns of male Wistar rats by Mehdi Graily-Afra, Farideh Bahrami, Zahra Bahari, Hedayat Sahraei, Zeinab Shankayi, Ali Gharib

“…Recordings of Rapid Eye Movement (REM) and Non-Rapid Eye Movement (NREM) sleep and wakefulness steps were made for the three hours prior to and three hours following the implementation of the immobility stress protocol and learning with the Barnes maze for three consecutive days. …”
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Features of Bearing on Underwater Object Using Phase Information of a Differential Stereo Sensor by V. A. Shirokov, A. I. Bazhenova, V. N. Milich

“…The presented method of error correction can be implemented programmatically. With a quasi-harmonious signal, rare measurements of the original signal are interpolated by frequent calculated values. …”
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Osimertinib plus anlotinib for advanced NSCLC with acquired EGFR T790M mutation: results from a multicenter phase II study with ctDNA analysis by Xinyue Wang, Zhaona Li, Liuchun Wang, Yan Liang, Chun Huang, Peng Chen, Dingzhi Huang, Xia Song, Cuimin Ding, Changli Wang, Richeng Jiang

“…Clearance of ctDNA, particularly of EGFR mutations, could serve as a valuable predictive biomarker, supporting the implementation of personalized treatment strategies. Trial registration ClinicalTrials.gov, NCT04029350.…”
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Intra-hospital patient-specific 3D printed surgical guide for patients with thoracic scoliotic deformities, the collaboration between engineer and surgeon by M. Suffo, M. Quiroga-De Castro, L Galán-Romero, P Andrés-Cano

“…The intra-hospital collaboration between engineers and surgeons was identified as a key factor in improving outcomes and reducing error risks, showcasing the benefits of interdisciplinary teamwork. …”
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An explainable Bi-LSTM model for winter wheat yield prediction by Abhasha Joshi, Biswajeet Pradhan, Subrata Chakraborty, Subrata Chakraborty, Renuganth Varatharajoo, Abdullah Alamri, Shilpa Gite, Chang-Wook Lee

“…Interpretability is another pressing and challenging issue in DL-based crop yield prediction, a factor that ensures the reliability of the model. …”
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Influence of wetted perimeters variation of physical cover porosity on the evaporation suppression effect of plains reservoirs in arid zones by Shaolei Wang, Kebin Shi, Kewu Han, Xueying Zhou, Xinjun Yan

“…Study focus: The implementation of anti-evaporation materials (e.g., foam boards, PE floats, etc.) on the water surface can be an effective strategy to mitigate ineffective evaporation losses. …”
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Impacts of Sandstorms on Chemistries of Ambient PAHs in a Small City in North China by Zhiyong Li, Zhen Zhai, Jixiang Liu, Lan Chen, Zhuangzhuang Ren, Chen Liu, Ziyi Zhan, Ziyuan Yue, Wenjia Zhu, Jihong Wei, Huiying Gao, Songtao Guo

“…Coal burning (CB) still held a high contribution to PAHs regardless of the implementation of “coal to gas” law in the sampling area. …”
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Impact of educational videos and user guide on indwelling pleural catheter caregiver training and unplanned healthcare encounters by Si Ling Young, Brian Lee Wei Chua, Qiao Li Tan, Carrie Kah-Lai Leong, Ivana Gilcrist Chiew Sian Phua, Jane Jing Yi Wong, Wen Ting Lim, Kendra Jing Ying Tang, Aaron Jun Jie Tan, Fena Ming Qin Lee, Ken Junyang Goh

“…There was no difference in overall complication and IPC-related infection rates between groups.Conclusion IPC-specific educational videos and resources, which are readily accessible and easily implemented into CGT programmes, reduce UHEs due to IPC-related issues and may improve caregiver knowledge and competency in IPC care and drainage.…”
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Machine learning-based integration identifies plasma cells-related gene signature ST6GAL1 in idiopathic pulmonary fibrosis by Fanjie Lin, Ken Lin, Donglei Li, Weiguo Kong, Jiayu Zhuang, Wei He, Xinguang Wei, Tianchi Xiao, Hao Zu, Zili Zhang, Wenju Lu

“…Finally, the network pharmacology analysis for the core gene was implemented. Results The established PCRGS, based on the seven genes (SLAMF7, JCHAIN, PNOC, POU2AF1, MEI1, ST6GAL1, and VOPP1), was identified as an independent prognostic factor for overall survival. …”
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Construction and validation of renal cell carcinoma tumor cell differentiation-related prognostic classification (RCC-TCDC): an integrated bioinformatic analysis and clinical study by Yifan Liu, Keqin Dong, Yuntao Yao, Bingnan Lu, Lei Wang, Guo Ji, Haoyu Zhang, Zihui Zhao, Xinyue Yang, Runzhi Huang, Wang Zhou, Xiuwu Pan, Xingang Cui

“…Subsequently, we conducted consensus clustering to construct the RCC tumor cell differentiation-related prognostic classification (RCC-TCDC) and implemented prognostic and multi-omics analyses. Moreover, we utilized Lasso regression to help develop a multivariable prognostic model. …”
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Diagnostic, Therapeutic, and Prognostic Applications of Artificial Intelligence (AI) in the Clinical Management of Brain Metastases (BMs) by Kyriacos Evangelou, Panagiotis Zemperligkos, Anastasios Politis, Evgenia Lani, Enrique Gutierrez-Valencia, Ioannis Kotsantis, Georgios Velonakis, Efstathios Boviatsis, Lampis C. Stavrinou, Aristotelis Kalyvas

“…Despite these advancements and the promising landscape, multiple challenges—including data availability and variability, decision-making interpretability, and ethical, legal, and regulatory concerns—limit the broader implementation of AI into the everyday clinical management of BMs. …”
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Curing using the minimal – Strategies for treatment reduction in childhood acute lymphoblastic leukemia by Bernice LZ Oh, Stephen P. Hunger, Allen EJ Yeoh, Shawn HR Lee

“…Future directions include potential implementation of immunotherapy upfront to low-risk ALL, which may allow for even further reducing toxic chemotherapy or treatment duration. …”
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Sources and Health Risks of PM2.5-bound PAHs in a Small City along with the “Clean Heating” Policy by Zhiyong Li, Ziyuan Yue, Jixiang Liu, Zhen Zhai, Jianwei Meng, Lei Wang, Jihong Wei, Dingyuan Yang, Ailian Hu, Wenjia Zhu, Ning Ding, Xiaoxia Lu, Chunhao Lin

“…The far lower PAHs in this study than those of small cities before CH implementation indicated the CH effectiveness. Higher diagnostic ratios (DRs) of FA/(FA + PY), BaA/(BaA + CHR), and IP/(IP + BgP) in the HS were in agreement with the increased coal/biomass usage. …”
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Measurement-Based Prediction of mmWave Channel Parameters Using Deep Learning and Point Cloud by Hang Mi, Bo Ai, Ruisi He, Anuraag Bodi, Raied Caromi, Jian Wang, Jelena Senic, Camillo Gentile, Yang Miao

“…Last, the deployment and implementation method of the proposed model is recommended to the readers.…”
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Effect of super absorbent polymer on quantitative and qualitative traits of cowpea (Vigna unguiculata L.) in low irrigation management conditions by Parvaneh Mombani, Seyed Keyvan Marashi

“…The second factor included three levels of super absorbent polymers: 1) Absence of super absorbent (control), 2) 75 Kg/ha and 3) 150 Kg/ha. …”
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Water quality index modelling and its application on artificial intelligence (AI) in conjunction with machine learning (ML) methodologies for mapping surface water potential zones... by Abhijeet Das

“…On the other hand, the degree of FA, were implemented to reduce inconsistencies, involving WQI index. …”
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