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    Nonbilayer Phospholipid Arrangements Are Toll-Like Receptor-2/6 and TLR-4 Agonists and Trigger Inflammation in a Mouse Model Resembling Human Lupus by Carlos Wong-Baeza, Alonso Tescucano, Horacio Astudillo, Albany Reséndiz, Carla Landa, Luis España, Jeanet Serafín-López, Iris Estrada-García, Sergio Estrada-Parra, Leopoldo Flores-Romo, Carlos Wong, Isabel Baeza

    Published 2015-01-01
    “…Mice with the lupus-like disease had increased serum concentrations of proinflammatory cytokines, C3a and C5a; they also had more TLR-4-expressing splenocytes, a higher expression of genes associated with TRIF-dependent TLR-4-signaling and complement activation, and a lower expression of apoptosis-related genes, compared to healthy mice. …”
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