Synthesis and propagation of complement C3 by microglia/monocytes in the aging retina. by Matt Rutar, Krisztina Valter, Riccardo Natoli, Jan M Provis

“…The number of C3-expressing microglia increased significantly by P750, and coincided spatiotemporally with thinning of the ONL, and up-regulation of Ccl- and Cxcl- chemokines.<h4>Conclusions</h4>Our data suggest that recruited microglia/monocytes contribute to activation of complement in the aging retina, through local expression of C3 mRNA. …”
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An independently tunable dual control system for RNAi complementation in Trypanosoma brucei. by Raveen Armstrong, Matt J Romprey, Henry M Raughley, Stephanie B Delzell, Matthew P Frost, James Chambers, Grace G Garman, David Anaguano, Michele M Klingbeil

“…This incomplete rescue emphasized the need for a more versatile induction system that will allow independent, tunable, and temporal regulation of gene expression. Hence, we adapted a dual control vanillic acid (Van)-Tet system that can independently control gene expression for robust RNAi complementation. …”
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Methodological Tools for the Implementation of Oil and Gas Projects on the arctic and Continental Shelf by S. E. Trofimov

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South African Rural Municipalities’ Innovation Lessons in Anti-poverty Policy Formulation, Assessment and Implementation by Tshililo Ruddy Farisani, Pfano Mashau

“…Suggested regulative processes that other rural municipalities within South Africa and beyond may implement in responding to disasters that threaten the sustainability of local rural livelihoods.…”
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LAWMAKING FORM THE IMPLEMENTATION OF ANTICORRUPTION POLICY by Andrei Petrovich Mazurenko

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Finerenone Alleviates Over-Activation of Complement C5a-C5aR1 Axis of Macrophages by Regulating G Protein Subunit Alpha i2 to Improve Diabetic Nephropathy by Zi-Han Li, Zi-Jun Sun, Sydney C. W. Tang, Ming-Hui Zhao, Min Chen, Dong-Yuan Chang

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An Inclusive Civil Society Dialogue for Successful Implementation of the EU HTA Regulation: Call to Action to Ensure Appropriate Involvement of Stakeholders and Collaborators by Thomas Desmet, Elaine Julian, Walter Van Dyck, Isabelle Huys, Steven Simoens, Rosa Giuliani, Mondher Toumi, Christian Dierks, Juliana Dierks, Antonella Cardone, Francois Houÿez, Mira Pavlovic, Michael Berntgen, Peter Mol, Anja Schiel, Wim Goettsch, Fabrizio Gianfrate, Stefano Capri, James Ryan, Pierre Ducournau, Oriol Solà-Morales, Jörg Ruof

“…The most important actions for regulators are to develop joint regulatory-HTA guidance documents, align processes and interfaces under the regulation, and share discussions on post-licensing evidence generation. …”
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Pragmatic clustered randomised control trial to evaluate a self-regulated learning intervention to be implemented in South Australian primary schools—study protocol by S.A Brinkman, B. Lam, S. Dawson, R. Marrone, D. Schunk, K. Winkel, H. Hermes, F. Gabriel, S. Fowler, D. Engelhardt

“…The primary outcome will be improved self-regulation assessed at 6 weeks, 6 months and 12 months post the intervention. …”
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D&R OBLIGATIONS OF OIL PRODUCING COMPANIES: ECONOMIC AND LEGAL MECHANISMS FOR IMPLEMENTATION by M. A. Valishvili

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Development of regulatory framework for public administration in the post-war situation in Ukraine in the context of the implementation of the Paris Agreement 2015 by V. Klymenko

“…The practical significance of the study lies in the fact that it proposes steps to improve the legal regulation of public administration in the period of post-war reconstruction in the context of implementation of an important international legal agreement…”
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A flipped classroom with whiteboard animation and modules to enhance students' self-regulation, critical thinking and communication skills: a conceptual framework and its implementation by Gede Suwardika, Agus Tatang Sopandi, I. Putu Oktap Indrawan, Kadek Masakazu

“…Findings – The findings demonstrate significant improvements in students' self-regulation, critical thinking skills and communication abilities after implementing the Flipped Classroom with Whiteboard Animation and Modules. …”
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CHROMOSOMAL COMPLEMENT AND DISTRIBUTION OF A WOLF (CANIS LUPUS L.) IN THE NORTH CAUCASUS by R. I. Dzuev, M. V. Suhomesova, V. N. Kanukova

“…The chromosomal complement of a Canis lupus L. in the North Caucasus is described for the first time in this work. …”
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Kidney Diseases Caused by Complement Dysregulation: Acquired, Inherited, and Still More to Come by Saskia F. Heeringa, Clemens D. Cohen

“…Therapeutic strategies for reestablishing complement regulation by either complement blockade with the anti-C5 monoclonal antibody eculizumab or plasma substitution have been successful in several cases of C3 glomerulopathies. …”
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Properties of local interactions and their potential value in complementing genome-wide association studies. by Wenhua Wei, Attila Gyenesei, Colin A M Semple, Chris S Haley

“…Analysing local interactions is a potentially valuable complement to GWAS and can provide new insights into the biology underlying variation in complex traits.…”
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Modification of the implementation of the underexcitation limiter within the generator excitation system of Unit B1 at TPP "Nikola Tesla B" by Klasnić Ilija, Veinović Slavko, Joksimović Dušan, Ivanović Luka, Radojičić Bojan, Brdarević Miloš

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Calfeutrer, contrôler, canaliser. Réflexion autour des dispositifs de traitement d’air en architecture by Eugénie Floret

Subjects: “…Regulations…”
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Personalised higher education based on microcourses: Possible ways of implementation by L. O. Denishcheva, I. S. Safuanov, Yu. A. Semenyachenko

“…The model of personalisation of education based on the use of microcourses, in addition to traditional sections, such as planned learning outcomes and a calendar curriculum, also contains new aspects (compared to current models of student learning): diagnostics of student’s capabilities in the implementation of personalisation; training regulations (including personal goals); schemes for the selection of general and additional modules, availability of initiative modules; diagnostics of achievements. …”
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Targeting the complement-mTOR-autophagy axis: the role of apolipoprotein E in depression by Yong Li, Chengyuan Xu, Jing Liu, Mengru Guo, Jia Wang, Xianbing Bai, Yujie Cheng, Xinyue Luan, Huailong Pei, Chenlei Zhang, Huan Liu, Ming Chen, Binliang Tang

“…Conclusions These findings demonstrate that ApoE regulates depressive behaviors by modulating the complement-mTOR-autophagy axis, identifying multiple potential therapeutic targets for clinical intervention in depression.…”
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The implementability and proximal effects of a transdiagnostic mental health intervention for adolescents (Kort): protocol for a mixed-methods intensive longitudinal study by Thomas Engell, Siri Saugestad Helland, Emily Gabriela Vira, Silje Berg, Line Solheim Kvamme, John Kjøbli, Josefine Bergseth, Inga Brenne, Ragnhild Bang Nes, Espen Røysamb, Line Brager-Larsen, Anette Jeneson, Ane Lønsetteig, Ole-Martin Vangen, Knut-Petter Leinan, Anneli Mellblom

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Legal Analysis of the Implementation of the Ten Steps to Successful Breastfeeding in Government Regulation Number 28 of 2024 to Support the Exclusive Breastfeeding Program in Indonesia by Ni Made Garnis Dolesgit

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