Differential chemoreactome analysis of synergistic combinations of tolperisone and nonsteroidal anti-inflammatory drugs by I. Yu. Torshin, O. A. Gromova, L. V. Stakhovskaya, V. A. Semenov, A. N. Gromov

“…The biological activities of the molecules under study were assessed in five sections: 1) inhibition of the proteins of prostaglandin and leukotriene metabolism; 2) inhibition of the effects of the transcription factor nuclear factor kappa, tumor necrosis factor-, and other anti-inflammatory mechanisms; 3) inhibition of excessive blood coagulation and platelet aggregation; 4) vasodynamic effects; 5) antitumor properties on cell lines in culture.Results and discussion. …”
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The psychologically rich life questionnaire: Italian validation and exploration of its relationships with mindfulness, self-compassion, and cognitive fusion within the health psych... by Federica Mauro, Federica Mauro, Michela Di Trani, Michela Di Trani, Luca Simione, Luca Simione

“…The confirmatory factor analysis revealed a good fit of the model for the one-factor structure. …”
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APOE4 triggers dysregulated synaptic vesicle release by disrupting SNARE complex assembly by Feng Chen, Yanting Chen, Sifan Feng, Huiyi Chen, Liehua Deng, Fubin Ma, Qiongwei Ke, Qiuhao Liang, Ji Chen, Xiaoping Peng, Jiongtong Lu, Yingxuan Liu, Yuying Xie, Hao Cao, Yuanhong Sun, Wenxian Wu, Lili Cui, Yan Wang

“…By using proteomics analysis, co-immunoprecipitation (Co-IP), and bimolecular fluorescence complementation (BiFC) assay, we demonstrated that APOE interacts with VAMP2, a core component of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, in an APOE4 > APOE3 manner. …”
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Morphological and phylogenetic analyses reveal two new species of the Fusarium fujikuroi (Hypocreales, Nectriaceae) species complex in China by Mingwei Zhang, Cheng Peng, Shuji Li, Chengming Tian

“…The present study delineates two novel Fusarium species within the FFSC, named F. castaneophilum and F. rubicola, complemented by illustrations and descriptions.…”
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Results of Maritime Spatial Planning in the EU by Marina L. Kolesnikova

“…The author drew a number of conclusions complementing the latest Russian research in the field of modern marine management. …”
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A vibration signal processing method based on SE-PSO-VMD for ultrasonic machining by Honghuan Chen

“…This paper presents a novel method, using Variational Mode Decomposition (VMD) to automatically decompose USM vibration signals into intrinsic mode functions (IMFs). This method is complemented by Particle Swarm Optimization (PSO) algorithm to optimize the number of IMFs and penalty factor, with Sample Entropy (SE) serving as a fitness function. …”
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Targeting HK3 in tumor-associated macrophages enhances antitumor immunity through augmenting antigen cross-presentation in cervical cancer by Hui Wang, Ying Chen, Min Wu, Jian Liu, Jingyu Wang, Yifan Yang, Chaoyang Sun, Shan He, Shen Qu, Xun Tian, Jinglan Chen, Han Jiang, Liting Liu, Yafei Huang

“…Single-cell RNA sequencing, complemented by flow cytometry analysis, was used to characterize hexokinase 3 (HK3)-expressing cell populations. …”
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A mechanism regulating the onset of Sox2 expression in the embryonic neural plate. by Costis Papanayotou, Anne Mey, Anne-Marie Birot, Yasushi Saka, Sharon Boast, Jim C Smith, Jacques Samarut, Claudio D Stern

“…In vertebrate embryos, the earliest definitive marker for the neural plate, which will give rise to the entire central nervous system, is the transcription factor Sox2. Although some of the extracellular signals that regulate neural plate fate have been identified, we know very little about the mechanisms controlling Sox2 expression and thus neural plate identity. …”
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Gendered Pathways to the Job Offer: Stereotypes and Diversity Value during Job Offer Decisions in Software Engineering Hiring by Koji Chavez

“…Drawing on qualitative data, the author finds that diversity considerations do play a role in job offers, but as an implicit motivational force during job offer deliberations rather than an explicitly stated factor. A quantitative analysis complements the qualitative analysis: the author finds no female penalty on receiving an offer where one might be expected, which the author argues is due to implicit diversity considerations during hiring deliberations. …”
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Neuroanatomical variability of religiosity. by Dimitrios Kapogiannis, Aron K Barbey, Michael Su, Frank Krueger, Jordan Grafman

“…We identified four Principal Components of religiosity by Factor Analysis of the survey items and associated them with regional cortical volumes measured by voxel-based morphometry. …”
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Analysis of intestinal epithelial cell responses to Cryptosporidium highlights the temporal effects of IFN-γ on parasite restriction. by Ryan D Pardy, Katelyn A Walzer, Bethan A Wallbank, Jessica H Byerly, Keenan M O'Dea, Ian S Cohn, Breanne E Haskins, Justin L Roncaioli, Eleanor J Smith, Gracyn Y Buenconsejo, Boris Striepen, Christopher A Hunter

“…These analyses were complemented by in vivo studies, which demonstrated that IEC expression of the IFN-γ receptor was required for parasite control. …”
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Electrostatics of salt-dependent reentrant phase behaviors highlights diverse roles of ATP in biomolecular condensates by Yi-Hsuan Lin, Tae Hun Kim, Suman Das, Tanmoy Pal, Jonas Wessén, Atul Kaushik Rangadurai, Lewis E Kay, Julie D Forman-Kay, Hue Sun Chan

“…The electrostatic nature of these features complements ATP’s involvement in π-related interactions and as an amphiphilic hydrotrope, underscoring a general role of biomolecular condensates in modulating ion concentrations and its functional ramifications.…”
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Dynamic monocyte changes as prognostic indicators in operable gastric cancer: a retrospective cohort analysis by Yiwei Jiang, Xianwei Sun, Chen Yang, Dandan Song, Chongjun Zhou, Xinxin Chen, Chongquan Huang, Zhonglin Wang, Jiante Li

“…We used Kaplan-Meier survival analysis, complemented by univariate and multivariate analyses. …”
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Modulation of Immune-Inflammatory Responses in Abdominal Aortic Aneurysm: Emerging Molecular Targets by Hanrong Li, Shuling Bai, Qiang Ao, Xiaohong Wang, Xiaohong Tian, Xiang Li, Hao Tong, Weijian Hou, Jun Fan

“…Recent evidence suggests that innate immune system, especially Toll-like receptors, chemokine receptors, and complements are involved in the progression of AAAs. …”
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Bidirectional two-sample Mendelian randomization analysis unveils causal association between inflammatory cytokines and the risk of diabetic nephropathy by Siyuan Song, Qianhua Yan, Jiangyi Yu

“…The primary analytical approach employed the inverse variance weighted (IVW) method, complemented by MR-Egger regression, weighted mode (WM), and weighted median (WME) methods to evaluate the causal association between inflammatory cytokines and DN. …”
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Accelerating Euclidean Distance Transforms: A Fast and Flexible Approach With Multi-Vendor GPU, Multi-Threading, and Multi-Language Support by Dale Black, Wenbo Li, Qiyu Zhang, Sabee Molloi

“…Benchmarks demonstrate substantial performance improvements, achieving speedups by a factor of 250 for 2D and a factor of 400 for 3D transforms compared to optimized CPU implementations. …”
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Enhancing titers of therapeutic lentiviral vectors using PKC agonists by Charles Moore-Kelly, Rajesh Reddem, Ben M. Alberts, Jordan Wright, Thomas Evans, Anurag Kulkarni, Nicholas G. Clarkson, Daniel C. Farley, Kyriacos A. Mitrophanous, Rui André Saraiva Raposo

“…Stimulation of HEK293T cells strongly upregulated AP-1 transcription factor subunits independently of nuclear factor κB (NF-κB) pathway activation. …”
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Bispecific Antibody Targeting VEGF/TGF‐β Synergizes with Local Radiotherapy: Turning Tumors from Cold to Inflamed and Amplifying Abscopal Effects by Lijuan Lyu, Ming Yi, Ji Chen, Jing Zhang, Xiaobin Ma, Xiaojun Zhang, Liang Zeng, Yan Xue, Haimei Wen, Yujiao Deng, Pengfei Zhou, Kongming Wu, Huafeng Kang, Zhijun Dai

“…Nevertheless, this immunogenic antitumor response may be partially counterbalanced by the upregulation of vascular endothelial growth factor (VEGF) and transforming growth factor‐beta (TGF‐β) induced by RT. …”
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Implementasi Kebijakan Pembebasan Biaya Kesehatan Dasar by Akadun Akadun

“…The result indicate that organization communication role for depending in implementing public policy successfull and become trigger other critical factor of implementing policy succesfull, as like resource, bureaucratic structure, and disposition or attitude. …”
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From ageing clocks to human digital twins in personalising healthcare through biological age analysis by Murih Pusparum, Olivier Thas, Stephan Beck, Simone Ecker, Gökhan Ertaylan

“…Abstract Age is the most important risk factor for the majority human diseases, leading to the exploration of innovative approaches, including the development of predictors to estimate biological age (BA). …”
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