How to design effective educational videos for teaching evidence-based medicine to undergraduate learners – systematic review with complementing qualitative research to develop a p... by Lukas Niekrenz, Cord Spreckelsen

“…In particular, studies on the requirements and design goals of educational videos need to be complemented by qualitative research using grounded theory methodology.Methods Due to the paucity of randomized controlled trials in this area, there is an urgent need to generate recommendations based on a broader fundament than a literature search alone. …”
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Elevated Plasma Complement C1Q Measured Subacutely after Traumatic Brain Injury Is Associated with Poor Functional Outcome Independent of Initial Injury Severity by Tracy Butler, Kewei Chen, Abigail Patchell, Xiangling Mao, Dikoma Shungu, Diany Paola Calderon, Jeanne T. Paz, Sudhin A. Shah

“…This study investigates the role of complement factor 1q (C1Q) in TBI recovery. Motivated by our rodent studies showing that thalamic inflammation post-TBI is dependent on C1Q and that blocking C1Q during the subacute period can prevent thalamic inflammation and improve aspects of TBI outcome, particularly sleep, we measured plasma C1Q levels 3–6 months post-injury in 27 patients with TBI ranging from complicated mild to severe, as well as 30 controls. …”
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X-ray repair cross-complementing group 1 (XRCC1) genetic polymorphisms and cervical cancer risk: a huge systematic review and meta-analysis. by Ya Li, Fei Liu, Shi-Qiao Tan, Yan Wang, Shang-Wei Li

“…<h4>Background</h4>Previous studies investigating the association between X-ray repair cross-complementation group 1(XRCC1) polymorphisms and cervical cancer (CC) risk has provided inconsistent results. …”
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Response gene to complement 32 promotes tumorigenesis by mediating DNA damage repair and inhibits CD8+ T cells infiltration in diffuse large B-cell lymphoma by Xiyuan Zhang, Xiyuan Zhang, Tiange Lu, Chunlei Shi, Mengfei Ding, Ling Wang, Xinting Hu, Xin Wang, Xin Wang

“…BackgroundResponse gene to complement 32 (RGC32), a complement activation-inducible factor broadly expressed in normal human tissues, has been implicated in tumorigenesis through its dysregulated expression in various malignancies and its involvement in critical oncogenic processes. …”
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Advancing Regional and Remote Health Care With Virtual Hospital Implementation: Rapid Review by Artika Archana Kumari, Tafheem Ahmad Wani, Michael Liem, James Boyd, Urooj Raza Khan

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Driving and Restraining Forces in the Implementation of Information Systems in the Public Sector: Scoping Review by Arja Lemmettylä, Ulla-Mari Kinnunen

“…ResultsThe findings highlight that IS implementation is influenced by 6 domains: organizational practices and challenges, technological factors and barriers, management practices and issues, change project factors and challenges, end user factors and concerns, as well as institutional factors and barriers. …”
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Novel Treatment Paradigms: Primary IgA Nephropathy by Haresh Selvaskandan, Jonathan Barratt, Chee Kay Cheung

“…Advancing insights into the pathophysiology of IgAN, including the roles of the mucosal immune system, B-cells, the complement system, and the endothelin system have driven development of therapies that target these factors. …”
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Implementation effectiveness of ‘Problem solving for better health’ training in Lesotho using mixed methods and the reach, effectiveness, adoption, implementation and maintenance (... by Doris Akolbire, Lora L. Sabin, Paballo P. Lethunya, Abhinav Sharma, Howard J. Cabral, Brian W. Jack, Nancy A. Scott

“…Some participants were able to start their projects but the inconsistency in follow-through suggests a need for more research into the factors that can improve completion of implementation for better health outcomes.…”
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Therapeutic targeting of alternative pathway and C5 but not C5a protects from disease development in a preclinical model of autoimmune blistering dermatosis by Björn Laffer, Mareike Ohms, Samyr Kenno, Ping Tsui, Elvira Ehlers-Jeske, Wenru Song, Wen-Chao Song, Jörg Köhl

“…IntroductionEpidermolysis Bullosa Acquisita (EBA) is an autoimmune blistering dermatosis characterized by autoantibodies (AAbs) against type VII collagen (COL7) located at the dermal epidermal junction (DEJ). Local complement activation drives C5a generation associated with neutrophil recruitment and activation resulting in skin lesions and inflammation. …”
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Text message intervention delivered from Australian general practices to improve breast cancer survivors’ physical activity and cardiovascular risk factors: protocol for the EMPOWER-SMS-GP effectiveness implementation randomised controlled trial by Karice K Hyun, Christine Mitchell, Julie Redfern, Nashid Hafiz, Rebecca Raeside, Brooke Nickel, Carolyn Ee, Jennifer McIntosh, Elisabeth Elder, Raymond J Chan, David Mizrahi, Stephanie R Partridge, Anna C Singleton, Allyson Ruth Todd, Kirsty E Stuart

“…Introduction Australian breast cancer survivors are at increased risk of cardiovascular disease and mortality, partly due to behavioural risk factors, including unhealthy diet and physical inactivity. …”
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Mitigation of Corruption by Implementing e-Government Using Soft Computing by Shareef M. Shareef

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Evaluating the Implementation of the Rapid Prenatal Exome Sequencing Service in England by Holly Walton, Morgan Daniel, Michelle Peter, Hannah McInnes-Dean, Rhiannon Mellis, Stephanie Allen, Naomi J. Fulop, Lyn S. Chitty, Melissa Hill

“…Findings were integrated. Results: Implementation was influenced by a range of factors including evidence of benefit, laboratory service reconfiguration, and stakeholder support. …”
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Implementasi Kebijakan Tanda Daftar Usaha Pariwisata melalui Sicantik pada Dinas Penanaman Modal dan Pelayanan Terpadu Satu Pintu Kota Medan by Lia Siska Endang, Marlon Sihombing, Maksum Syahri Lubis

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Green Jobs Creation – Main Element in the Implementation of Bioeconomic Mechanisms by Florin-Alexandru Luca, Gheorghe Epuran, Claudia-Ioana Ciobanu, Adrian V. Horodnic

“…Green jobs creation is the main element in the implementation of bioeconomy mechanisms along with other factors, such as gross domestic product (GDP), environmental protection and national security. …”
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Challenges in the Implementation of Curriculum Based on the Indonesian National Qualification Framework by Magdahalena Tjalla, Abdul Haris Sunubi

“…The research also showed the causes of the difficulties of curriculum implementation: student factors, lecturer factors, and institutional factors.…”
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Exploring implementation of interventions to facilitate integration in fragmented healthcare systems by Cassandra Bragdon, Rachel Siden, Marcy Winget, Sonia Rose Harris, Rebecca Carey, Justin Ko, Alpa Vyas, Cati Brown‐Johnson

“…This study aimed to explore the complexities of moving from a fragmented to an integrated academic healthcare system and to identify and explain factors (e.g., facilitators and barriers) of the implementation of three interventions meant to improve patient experience, reduce staff burden, and integrate health care systems across faculty and community settings. …”
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A Model for Creating and Implementing Ambidextrous Innovation in Iranian Banking by Vahid Khashei Varnamkhasti, Sajad Farsi

“…These interviews helped identify the key factors influencing the development and implementation of ambidextrous innovation in the industry. …”
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POLICY IMPLEMENTATION TO ACCELERATE STUNTING REDUCTION: A QUALITATIVE STUDY by Demsa Simbolon, Tonny Cortis Maigoda, Meriwati, Solha Efrida, Yunita, Heny Widiastuti

“…Aims: This study aims to analyze and evaluate the implementation of PPS policies and identify supporting and inhibiting factors. …”
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CONCEPTUAL AND THEORETICAL FOUNDATIONS OF POLICY AND PROGRAMME IMPLEMENTATION IN BENUE STATE by CHRIS S. ORNGU

“…It concludes that since its creation, Benue State has not recorded a significant milestone in its policy formulation and programme implementation as a result of discontinuities, political factors as well as economic forces, among others. …”
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PRIVATIZED VIOLENCE: THE ESSENCE AND TYPES OF ITS IMPLEMENTATION IN MODERN WORLD by Микола Адамович Козловець, Вадим Миколайович Слюсар

“…On the basis of the historical experience analysis and modern practice, the content and specifics of the privatized violence manifestation, mechanisms and factors of its implementation in the modern world are investigated. …”
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