Enabling clinical use of linear energy transfer in proton therapy for head and neck cancer – A review of implications for treatment planning and adverse events study by Chen Jingyuan, Yang Yunze, Feng Hongying, Liu Chenbin, Zhang Lian, Holmes Jason M., Liu Zhengliang, Lin Haibo, Liu Tianming, Simone Charles B., Lee Nancy Y., Frank Steven J., Ma Daniel J., Patel Samir H., Liu Wei

“…However, the clinical implementation is challenged by the oversimplification of the relative biological effectiveness (RBE) as a fixed value of 1.1, which does not account for the complex interplay between dose, linear energy transfer (LET), and biological endpoints. …”
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Long-term monitoring data on Popillia japonica (Newman, 1838) (Coleoptera, Rutelidae) across the Azorean Islands by Mário Teixeira, António Soares, David Lopes, Lucas Lamelas-Lopez, Paulo Borges, José Mota, Nelson Simões

“…For more than 16 years, the Azorean official authorities have implemented a Long-Term Ecological Research (LTER) programme that is crucial for understanding the dynamics of insect pests, such as the Japanese Beetle, and their impacts on agricultural ecosystems. …”
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The ‘FebBenz’ approach for severe difficult-to-treat gout by Enrique Calvo-Aranda, Claudia María Gómez-González, Fernando Pérez-Ruiz, Marta Novella-Navarro

“…A two-step treatment regimen was implemented: a 6-month dose escalation of the FBX dose followed by add-on BNZ. …”
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Breast cancer risk and prevention in 2024: An overview from the Breast Cancer UK ‐ Breast Cancer Prevention Conference by Britta Stordal, Michelle Harvie, Michael N. Antoniou, Michelle Bellingham, Doris S. M. Chan, Philippa Darbre, Oskar Karlsson, Andreas Kortenkamp, Pamela Magee, Stefano Mandriota, Elisabete Silva, James E. Turner, Laura N. Vandenberg, D. Gareth Evans

“…Behaviour‐related research needs to focus on implementation as well as deeper understanding of the mechanisms of cancer prevention.…”
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Impacts of Sandstorms on Chemistries of Ambient PAHs in a Small City in North China by Zhiyong Li, Zhen Zhai, Jixiang Liu, Lan Chen, Zhuangzhuang Ren, Chen Liu, Ziyi Zhan, Ziyuan Yue, Wenjia Zhu, Jihong Wei, Huiying Gao, Songtao Guo

“…Coal burning (CB) still held a high contribution to PAHs regardless of the implementation of “coal to gas” law in the sampling area. …”
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Urinary tract infection in adults: gaps in current guidelines – opinions from an international multidisciplinary panel and relevance to clinical practice by Kalpana Gupta, Florian Wagenlehner, Mark Wilcox, Sonali D. Advani, Manu Bilsen, Gernot Bonkat, Rafael Cantón, Suzanne Geerlings, Beatrice Grabein, Juan P. Horcajada, Pamela Kushner, Navaneeth Narayanan, Marc Scheetz

“…Patients with cUTIs are not a homogeneous group and differences in risk factors and prognosis should be considered. However, a balance must be sought between appropriate antimicrobial treatment and complexity of guidelines, which can hinder their implementation, especially in primary care. …”
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Cohort profile: evaluation of immune response and household transmission of SARS-CoV-2 in Costa Rica: the RESPIRA study by Allan Hildesheim, Tim Waterboer, Julia Butt, Mitchell H Gail, Alejandro Calderón, Rolando Herrero, Carolina Porras, Bernal Cortes, Viviana Loría, Amada Aparicio, Gloriana Barrientos, Daniela Retana, Kaiyuan Sun, Rebeca Ocampo, D. Rebecca Prevots, Michael Zúñiga, Roy Wong-McClure, Melvin Morera, Marco Binder, Arturo Abdelnour, Ruth M Pfeiffer, Cristina Barboza Solís, Romain Fantin, Juan Carlos Vanegas, Rachel Mercado, Carlos Ávila

“…During the study, national vaccination was implemented and nearly 90% of our cohort participants were vaccinated during follow-up.Future plans RESPIRA will enable multiple analyses, including population prevalence of infection, clinical, behavioural, immunological and genetic risk factors for SARS-CoV-2 acquisition and severity, and determinants of household transmission. …”
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Community-based organization perspectives on participating in state-wide community canvassing program aimed to reduce COVID-19 vaccine disparities in California by Lisa N. Mansfield, Savanna L. Carson, Nisha Sunku, Alana Troutt, Shelli Jackson, David Santillan, Stefanie D. Vassar, Dale Slaughter, Gloria Kim, Keith C. Norris, Arleen F. Brown

“…Key facilitators included leveraging trust through recognized entities; promoting empathetic, tailored outreach; and flexibility of milestone-based CBO funding contracts for rapid program implementation. Barriers included navigating community sociopolitical, geographic, and cultural factors; managing canvassers’ safety; desiring metrics for self-evaluation of outreach success; mitigating canvassing technology challenges; and concerns of program infrastructure initially limiting outreach. …”
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Cytomegalovirus Reactivation Is Associated With Lower Rates of Hepatocellular Carcinoma Recurrence After Liver Transplantation by Victoria Aguilera, Sarai Romero Moreno, Isabel Conde, Angel Rubín, Angela Carvalho-Gomes, Mario Romero, Javier Zamora-Olaya, Miguel Angel Gómez-Bravo, Esteban Fuentes-Valenzuela, Cristina Dopazo, Nikita Bilbao, Antonio González, Ana Sánchez-Martínez, Sonia Pascual, Jesús Rivera-Esteban, José Ignacio Herrero, Sara Lorente, Antonio Cuadrado-Lavín, Flor Nogueras, Laura Martínez-Arenas, Rocío González-Grande, Marina Berenguer, Manuel Rodriguez-Perálvarez

“…CMV prophylaxis was implemented for 19.7% of patients, while the rest were managed with preemptive therapy. …”
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Impact of digital health on Type 2 diabetes management: a randomised controlled trial of the ‘TreC Diabete’ platform (TELEMECHRON Study) by Alexia Giovanazzi, Lorenzo Gios, Maria Adalgisa Gentilini, Marina Mastellaro, Patrizia Bartolotta, Lucrezia Nicolussi Giacomaz, Claudio Eccher, Sandro Inchiostro

“…Study generalisability may be limited by the sample’s demographics, as the trial predominantly included younger male individuals with a specific HbA1c level.ConclusionThe study highlighted key factors for future implementations, including understanding technology benefits, addressing adoption barriers, and providing education and support to both patients and healthcare providers.…”
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Food safety knowledge, attitudes, and practices among food handlers in collective catering in central Morocco by Rachid Amaiach, Abdelhakim El Ouali Lalami, Mouhcine Fadil, Rabia Bouslamti, Sanae Lairini

“…This pioneering study in central Morocco aimed to assess food safety knowledge, attitudes, and practices (KAPs) among food handlers and to identify key factors influencing adequate knowledge, positive attitudes, and effective practices. …”
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How did New Zealand’s regional District Health Board groupings work to improve service integration and health outcomes: a realist evaluation by Robin Gauld, Rosalina Richards, Tim Stokes, Trudy Sullivan, Fiona Doolan-Noble, Andrew R Gray, Carol Atmore, Erin Penno, Lauralie Richard, Emma Wyeth, Brett Maclennan

“…We used documentary analysis to develop programme logic models to describe the context, structure, capabilities, implementation activities and impact of each of the four regional groupings and then conducted interviews with stakeholders. …”
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Predicting the reduction in heatstroke and heart disease-related mortality under urban modification scenarios using machine learning by Yukitaka Ohashi, Ko Nakajima, Yuya Takane, Yukihiro Kikegawa, Tomohiko Ihara, Kazutaka Oka

“…The results suggest that the implementation of urban modifications can effectively reduce heat-related deaths, especially during heatwaves and extremely hot summers.…”
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Hydroalcoholic extract of Punica granatum L. (pomegranate) leaf: A promising phytotherapeutic agent against oral pathogens by Luciana Cláudia Diniz Tavares, Mariana Simões de Oliveira, Bernardo Canêdo Martins, Daphne Fonseca Coppoli Lanferini, Benjamin Fragneaud, Antonio Carlos Sant’ana, Guilherme Diniz Tavares, Ana Carolina Morais Apolônio

“…Dental biofilm (DB) is a complex microbial structure in which implementing an appropriate approach to prevent its development is difficult due to the diversity of microorganisms and the genetic and environmental factors that contribute to its formation. …”
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The effect of acupuncture on blood glucose control in patients with type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials by Yuqi Si, Jiayao Chen, Lizhu Chen, Yan Zheng, Yixuan Qiu, Beibei Wang, Yiwen Liang, Yubo Zhang, Yaling Chen

“…The meta-analysis was implemented leveraging RevMan 5.4 and Stata 15 software, with sensitivity and subgroup analyses to assess the stability of results and identify heterogeneity sources.Results21 RCTs encompassing 2,117 individuals with T2DM were analyzed. …”
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Efficacy test of a Mycoplasma hyorhinis mRNA-LNP vaccine candidate by Eszter Zsófia Nagy, Levente Szeredi, Hiromi Muramatsu, Noémi Nagy, Dénes Grózner, Zsuzsa Kreizinger, Kinga M. Sulyok, Bandana Pangabam, Lilla Tóth, Rachel H.J. Jun, Dorottya Földi, Enikő Wehmann, Miklós Tenk, Norbert Pardi, Miklós Gyuranecz

“…Currently, prevention and treatment strategies rely on mitigating risk factors and administering antibiotics, as no vaccines are commercially available in Europe. …”
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Successful termination of a multi-year wastewater-associated outbreak of NDM-5-carrying E. coli in a hemato-oncological center by Heidrun Kerschner, Linda Jernej, Adriana Cabal, Patrick Hyden, Sigrid Machherndl-Spandl, Lucia Berning, Anna Blaimschein, Werner Ruppitsch, Petra Apfalter, Rainer Hartl

“…Additionally, colonized patients were instructed to use wheeled commodes instead of toilets, and a pre-admission screening strategy was implemented for all patients undergoing hematologic stem cell transplantation. …”
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Climate-smart agronomic practices and their appraisal among smallholder sorghum farmers in eastern Democratic Republic of Congo wetlands by Géant B. Chuma, Latifah Kisombola, Jean M. Mondo, Boaz Muliri, Jackson-Gilbert M. Majaliwa, Charles Kahindo, Katcho Karume

“…This study specifically aims at identifying CSA practices in use and factors driving their adoption among sorghum farmers and assessing their efficiency in improving sorghum yield under smallholder farming in South-Kivu. …”
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Assessing the foreign economic security of Ukraine by Yuliia Yehorova, Svitlana Chorna, Yuriy Petrushenko, Fedir Zhuravka, Khrystyna Potapenko, Iryna D’yakonova, Oksana Zamora

“…The results demonstrate that the main factors affecting the foreign economic security index are global economic crises, domestic political changes, and a full-scale war with russia. …”
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Evaluating the performance of a virtual platform ‘T-BOM’ for mentorship in tropical diseases research among early career scientists: Insights from a pilot in Nigeria and other reso... by Hammed Oladeji Mogaji, Akan Itinah, Oyinkansola Suliat Fadiji, Olamide Olaitan Omitola, Tawkalitu Eniola Mogaji, Olajide Murtala Keshinro, Falilat Eniola Mogaji, Mahmud Umar Ali, Moses Aikins, Franklin N. Glozah, Dako-Gyeke Phyllis, Uwem Friday Ekpo

“…Interpretation: The achievements of T-BOM over a period of one-year are challenged by intrinsic factors from both mentees and mentors, as well as erratic internet services in resource-limited settings. …”
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