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  1. 661

    Can theory-driven implementation interventions help clinician champions promote opioid stewardship after childbirth? Protocol for a pragmatic implementation study by Michelle H. Moniz, Michelle H. Moniz, Michelle H. Moniz, Amy M. Kilbourne, Amy M. Kilbourne, Alex F. Peahl, Alex F. Peahl, Alex F. Peahl, Jennifer F. Waljee, Jennifer F. Waljee, Jennifer F. Waljee, Shelytia Cocroft, Carey Simpson, Carey Simpson, Lisa Kane Low, Lisa Kane Low, Lisa Kane Low, Mark C. Bicket, Mark C. Bicket, Mark C. Bicket, Michael J. Englesbe, Michael J. Englesbe, Michael J. Englesbe, Molly J. Stout, Molly J. Stout, Vidhya Gunaseelan, Vidhya Gunaseelan, Althea Bourdeau, Althea Bourdeau, May Hu, Carrie Miller, Carrie Miller, Shawna N. Smith, Shawna N. Smith, Shawna N. Smith

    Published 2025-03-01
    “…Using interrupted time series analyses, the primary analysis will evaluate the rate of postpartum opioid-sparing prescribing metrics at the time of discharge (primary outcome) and opioid prescription refills and high-risk prescribing (secondary outcomes) before and after CPG implementation with REP. We will evaluate inequities in outcomes by patient, procedure, prescriber, and hospital factors. …”
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  2. 662

    X-ray repair cross-complementing group 1 (XRCC1) genetic polymorphisms and cervical cancer risk: a huge systematic review and meta-analysis. by Ya Li, Fei Liu, Shi-Qiao Tan, Yan Wang, Shang-Wei Li

    Published 2012-01-01
    “…<h4>Background</h4>Previous studies investigating the association between X-ray repair cross-complementation group 1(XRCC1) polymorphisms and cervical cancer (CC) risk has provided inconsistent results. …”
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  3. 663

    Elevated Plasma Complement C1Q Measured Subacutely after Traumatic Brain Injury Is Associated with Poor Functional Outcome Independent of Initial Injury Severity by Tracy Butler, Kewei Chen, Abigail Patchell, Xiangling Mao, Dikoma Shungu, Diany Paola Calderon, Jeanne T. Paz, Sudhin A. Shah

    Published 2025-01-01
    “…This study investigates the role of complement factor 1q (C1Q) in TBI recovery. Motivated by our rodent studies showing that thalamic inflammation post-TBI is dependent on C1Q and that blocking C1Q during the subacute period can prevent thalamic inflammation and improve aspects of TBI outcome, particularly sleep, we measured plasma C1Q levels 3–6 months post-injury in 27 patients with TBI ranging from complicated mild to severe, as well as 30 controls. …”
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  4. 664

    Response gene to complement 32 promotes tumorigenesis by mediating DNA damage repair and inhibits CD8+ T cells infiltration in diffuse large B-cell lymphoma by Xiyuan Zhang, Xiyuan Zhang, Tiange Lu, Chunlei Shi, Mengfei Ding, Ling Wang, Xinting Hu, Xin Wang, Xin Wang

    Published 2025-07-01
    “…BackgroundResponse gene to complement 32 (RGC32), a complement activation-inducible factor broadly expressed in normal human tissues, has been implicated in tumorigenesis through its dysregulated expression in various malignancies and its involvement in critical oncogenic processes. …”
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  5. 665

    How to design effective educational videos for teaching evidence-based medicine to undergraduate learners – systematic review with complementing qualitative research to develop a p... by Lukas Niekrenz, Cord Spreckelsen

    Published 2024-12-01
    “…Drawing on these results, the authors elaborated a guide for creating effective educational videos.Results The authors identified 40 effective or presumedly effective factors fostering the success of video-based eLearning in teaching evidence-based medicine, providing a ready-to-use checklist. …”
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  6. 666
  7. 667

    Driving and Restraining Forces in the Implementation of Information Systems in the Public Sector: Scoping Review by Arja Lemmettylä, Ulla-Mari Kinnunen

    Published 2025-06-01
    “…ResultsThe findings highlight that IS implementation is influenced by 6 domains: organizational practices and challenges, technological factors and barriers, management practices and issues, change project factors and challenges, end user factors and concerns, as well as institutional factors and barriers. …”
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  8. 668

    Therapeutic targeting of alternative pathway and C5 but not C5a protects from disease development in a preclinical model of autoimmune blistering dermatosis by Björn Laffer, Mareike Ohms, Samyr Kenno, Ping Tsui, Elvira Ehlers-Jeske, Wenru Song, Wen-Chao Song, Jörg Köhl

    Published 2025-04-01
    “…IntroductionEpidermolysis Bullosa Acquisita (EBA) is an autoimmune blistering dermatosis characterized by autoantibodies (AAbs) against type VII collagen (COL7) located at the dermal epidermal junction (DEJ). Local complement activation drives C5a generation associated with neutrophil recruitment and activation resulting in skin lesions and inflammation. …”
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  9. 669

    Novel Treatment Paradigms: Primary IgA Nephropathy by Haresh Selvaskandan, Jonathan Barratt, Chee Kay Cheung

    Published 2024-02-01
    “…Advancing insights into the pathophysiology of IgAN, including the roles of the mucosal immune system, B-cells, the complement system, and the endothelin system have driven development of therapies that target these factors. …”
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  10. 670

    Implementation effectiveness of ‘Problem solving for better health’ training in Lesotho using mixed methods and the reach, effectiveness, adoption, implementation and maintenance (... by Doris Akolbire, Lora L. Sabin, Paballo P. Lethunya, Abhinav Sharma, Howard J. Cabral, Brian W. Jack, Nancy A. Scott

    Published 2025-01-01
    “…Some participants were able to start their projects but the inconsistency in follow-through suggests a need for more research into the factors that can improve completion of implementation for better health outcomes.…”
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    PRIVATIZED VIOLENCE: THE ESSENCE AND TYPES OF ITS IMPLEMENTATION IN MODERN WORLD by Микола Адамович Козловець, Вадим Миколайович Слюсар

    Published 2020-12-01
    “…On the basis of the historical experience analysis and modern practice, the content and specifics of the privatized violence manifestation, mechanisms and factors of its implementation in the modern world are investigated. …”
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  15. 675
  16. 676

    Building information modeling: implementation challenges in the Malawian construction industry by Melusi Ndwandwe, Witness Kuotcha, Theresa Mkandawire

    Published 2024-11-01
    “…Thus, through factor analysis, the study divided the 20 BIM implementation challenges into three categories: BIM integration, collaborative workflow, and technical adaptability challenges. …”
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    Development of company Internet promotion strategy and tools for its implementation by A. E. Zhuravel, V. F. Zhuravel, V. Yu. Makarieva, M. I. Bessolitsyna

    Published 2023-05-01
    “…Currently, information technologies are a factor of new methods of the company's development into the global market space via the Internet. …”
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  20. 680