Rheumatoid Factor, Complement, and Mixed Cryoglobulinemia by Peter D. Gorevic

“…Low serum level of complement component 4 (C4) that occurs in mixed cryoglobulinemia (MC) may be due to in vivo or ex vivo activation of complement by the classical pathway. …”
Get full text

Complement factor H in molecular regulation of angiogenesis by Li Jiang, Wang Kaili, Starodubtseva Maria N., Nadyrov Eldar, Kapron Carolyn M., Hoh Josephine, Liu Ju

Subjects: “…complement factor h…”
Get full text

Regulation of anti-microbial autophagy by factors of the complement system by Christophe Viret, Aurore Rozières, Rémi Duclaux-Loras, Gilles Boschetti, Stéphane Nancey, Mathias Faure

“…Both surface receptor-ligand interactions and intracellular interactions are involved in the modulation of the autophagic response to intracellular microbes by complement factors. Here, we review works that relate to the recently discovered connections between factors of the complement system and the functioning of autophagy in the context of host-pathogen relationship.…”
Get full text

Clinical values of serum Gd-IgA1， complement factor H and complement regulatory proteins in IgA nephropathy by Zou Mei, Xue Hen, Lu Fang-cao, Zheng Guang-yi, Zhao Min

Subjects: Get full text

Glycoproteomics analysis of complement factor H and its complement-regulatory function during Streptococcus pneumoniae-associated hemolytic uremic syndrome by Laura M. Baas, Kioa L. Wijnsma, Fokje Zijlstra, Nicole C. A. J. van de Kar, Lieke ter Steeg, Antonia H. M. Bouts, Marloes A. H. M. Michels, Marloes A. H. M. Michels, Jeroen D. Langereis, Dirk Lefeber, Dirk Lefeber, Hans J. C. T. Wessels, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel, Lambertus P. van den Heuvel

Subjects: “…complement factor H…”
Get full text

Outer membrane protein OMP76 of Riemerella anatipestifer contributes to complement evasion and virulence by binding to duck complement factor vitronectin by Sen Li, Yanhua Wang, Rongkun Yang, Xiaotong Zhu, Hongying Bai, Xiaojian Deng, Jiao Bai, Yang Zhang, Yuncai Xiao, Zili Li, Zhengfei Liu, Zutao Zhou

“…Pathogenic bacteria recruit host complement factors to resist the bactericidal effect of serum complement. …”
Get full text

The specific contributions of factor H and factor I in controlling fluid phase activation of the alternative complement pathway by Nancy A. Turner, Joel L. Moake

“…Abstract The immediate defense provided by the alternative complement pathway (AP) is under constant control by fluid phase regulators, factor H (FH) and factor I (FI), to prevent nonessential activation. …”
Get full text

Candidiasis: Insights into Virulence Factors, Complement Evasion and Antifungal Drug Resistance by Nidaa Riaz Gaffar, Nisha Valand, Umakhanth Venkatraman Girija

Get full text

Complement Factor C7 Contributes to Lung Immunopathology Caused by Mycobacterium tuberculosis by Kerry J. Welsh, Cole T. Lewis, Sydney Boyd, Michael C. Braun, Jeffrey K. Actor

“…Increasing evidence indicates a critical role of the complement system in the development of host protection against the bacillus, but few studies have specifically explored the function of the terminal complement factors. …”
Get full text

Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility. by Jian Zhao, Hui Wu, Melanie Khosravi, Huijuan Cui, Xiaoxia Qian, Jennifer A Kelly, Kenneth M Kaufman, Carl D Langefeld, Adrienne H Williams, Mary E Comeau, Julie T Ziegler, Miranda C Marion, Adam Adler, Stuart B Glenn, Marta E Alarcón-Riquelme, BIOLUPUS Network, GENLES Network, Bernardo A Pons-Estel, John B Harley, Sang-Cheol Bae, So-Young Bang, Soo-Kyung Cho, Chaim O Jacob, Timothy J Vyse, Timothy B Niewold, Patrick M Gaffney, Kathy L Moser, Robert P Kimberly, Jeffrey C Edberg, Elizabeth E Brown, Graciela S Alarcon, Michelle A Petri, Rosalind Ramsey-Goldman, Luis M Vilá, John D Reveille, Judith A James, Gary S Gilkeson, Diane L Kamen, Barry I Freedman, Juan-Manuel Anaya, Joan T Merrill, Lindsey A Criswell, R Hal Scofield, Anne M Stevens, Joel M Guthridge, Deh-Ming Chang, Yeong Wook Song, Ji Ah Park, Eun Young Lee, Susan A Boackle, Jennifer M Grossman, Bevra H Hahn, Timothy H J Goodship, Rita M Cantor, Chack-Yung Yu, Nan Shen, Betty P Tsao

“…Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins (CFHR1-CFHR5) within the chromosome 1q32 locus linked to SLE, have been associated with multiple human diseases and may contribute to dysregulated complement activation predisposing to SLE. …”
Get full text

Safety Analysis of Agricultural Implement for Mulching and Soil Covering by In-Seok Hwang, Sung-Min Ji, Wan-Tae Im, Chang-Seop Shin

Get full text

Differential modulation of SARS-CoV-2 infection by complement factor H and properdin by Uday Kishore, Uday Kishore, Praveen M. Varghese, Chandan Kumar, Susan Idicula-Thomas, Martin Mayora Neto, Anthony G. Tsolaki, Pretty Ponnachan, Pretty Ponnachan, Khaled Masmoudi, Basel Al-Ramadi, Basel Al-Ramadi, Manu Vatish, Taruna Madan, Taruna Madan, Nigel Temperton, Nazar Beirag, Nazar Beirag

Subjects: Get full text

Activation of complement factor B contributes to murine and human myocardial ischemia/reperfusion injury. by Nicholas Chun, Ala S Haddadin, Junying Liu, Yunfang Hou, Karen A Wong, Daniel Lee, Julie I Rushbrook, Karan Gulaya, Roberta Hines, Tamika Hollis, Beatriz Nistal Nuno, Abeel A Mangi, Sabet Hashim, Marcela Pekna, Amy Catalfamo, Hsiao-Ying Chin, Foramben Patel, Sravani Rayala, Ketan Shevde, Peter S Heeger, Ming Zhang

“…Whether factor B (fB), a component of the alternative complement pathway required for amplification of complement cascade activation, participates in the pathophysiology of myocardial I/R injury has not been addressed. …”
Get full text

Catastrophic antiphospholipid syndrome accompanied by complement regulatory gene mutation by Serim Pul, Betül Sözeri, Cemile Pehlivanoğlu, Deniz Filinte, Özde Nisa Türkkan, Mehtap Sak, Neslihan Çiçek, Serçin Güven, Ece Demirci Bodur, İbrahim Gökçe, Harika Alpay

Subjects: Get full text

Relationship of gene polymorphisms for complement components C3 and factor H and kidney allograft function by Marija Milinkovic, Vladimir Perovic, Stefan Maksimovic, Irena Vukovic, Milica Kravljaca, Voin Brkovic, Iman Assi Milosevic, Milan Radovic, Mirjana Lausevic

“…Abstract Complement plays a central role in organ ischemia/reperfusion injury (IRI) and allograft rejection. …”
Get full text

A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion. by Quynh Huong Nguyen, Chun Heng Royce Lai, Michael J Norris, Dixon Ng, Megha Shah, Christine Chieh-Lin Lai, David E Isenman, Trevor F Moraes

“…Here, we report that PmSLP binds host complement factor I (FI) and facilitates cleavage of complement components C3b and C4b independently of any cofactors (e.g., FH, C4BP), thereby allowing the pathogen to evade host defence. …”
Get full text

In trans complementation of lethal factor reveal roles in colonization and dissemination in a murine mouse model. by David E Lowe, Jason Ya, Ian J Glomski

“…Lethal factor (LF) is a component of the B. anthracis exotoxin and critical for pathogenesis. …”
Get full text

Urinary Complement Factor Ba: A New Tool for Early Detection of Acute Kidney Injury by Daan P.C. van Doorn, Augusto Cesar Soares dos Santos Junior, Sjoerd A.M.E.G. Timmermans

Get full text

Complement-Inhibiting Therapy of Atypical Haemolytic Uremic Syndrome in a Patient With Factor H Mutation by Irina N. Lupan, Alexander Yu. Pischalnikov, Hadizha M. Emirova, Ekaterina S. Stolyarevich, Alexander M. Volyansky, Larisa V. Glukhova

“…Atypical haemolytic uremic syndrome (aHUS) is an extremely rare pathology with the development of complement-mediated thrombotic microangiopathy (TMA). …”
Get full text

Defining Nephritic Factors as Diverse Drivers of Systemic Complement Dysregulation in C3 Glomerulopathy by Jill J. Hauer, Yuzhou Zhang, Renee Goodfellow, Amanda Taylor, Nicole C. Meyer, Sarah Roberts, Dingwu Shao, Lauren Fergus, Nicolo Ghiringhelli Borsa, Monica Hall, Carla M. Nester, Richard J.H. Smith

Subjects: “…complement dysregulation…”
Get full text