A LINK BETWEEN AUTOPHAGY REGULATORY PROTEINS M-TOR AND BECLIN-1 AND PARAMETERS OF LYMPHOGENIC METASTASIS IN COLORECTAL CANCER by S. V. Vtorushin, K. V. Rachkovsky, N. V. Krakhmal, I. V. Stepanov, M. V. Zavyalova

“…The obtained findings clearly exhibit that deceleration or loss of autophagic  activity in the tumor is accompanied by implementation of lymphogenic dissemination, which is a predictor of an unfavorable outcome of the disease.…”
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BEHAVIOUR OF INDIVIDUAL CONSUMERS AS AN OBJECT MANAGEMENT INTERESTS by Yurii Y. Petrunia, Vira Y. Petrunia, Olexander I. Guba

“…The article deals with the reasons, directions and scope of the interest of society, institutions of state regulation and managers of business structures concerning the behavior of households as consumers. …”
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IoT Readiness Model for Urban Vocational School: Case Study in Indonesia by Novian Anggis Suwastika, Maslin Masrom, Qori Qonita, Misita Anwar

“… The Internet of Things (IoT) holds significant potential to enhance vocational education, yet its implementation in this sector remains limited and has a low success rate. …”
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Access to Written Submissions in Preliminary Reference Proceedings: An Evaluation of the CJEU Statute Reform and its Contribution to Open Justice by Ilaria Fevola, Stefano Montaldo

“…Indirect access to Court proceedings through the Transparency Regulation 1049/2001. – 4.3. Voluntary disclosure by the parties to a case. – 5. …”
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A blockchain secured metaverse framework for scalable and immersive telemedicine by Rahul Ganpatrao Sonkamble, Swati Shirke-Deshmukh, Vijay Katkar, M. Lunagaria, Ganshyam G. Tejani, Seyed Jalaleddin Mousavirad

“…The Metaverse serves as the foundation for the implementation of 3D consultation rooms, virtual training spaces, and individual care. …”
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DIAGNOSTIC SIGNIFICANCE OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN PATIENTS WITH PRIMARY MITRAL VALVE PROLAPSE by A. V. Yagoda, N. N. Gladkikh, Т. E. Zangelova

“…In primary MVP patients, regardless clinical phenotype of monogenic hereditary syndromes, the heterogeneity of deviation and regulation of VEGF has been established. Highest number of II grade mitral regurgitation, significant rhythm disorders was found in the group with low VEGF-A and VEGF-A/VEGF-R1, that might be implemented as optimized risk stratification in heterogenic MVP patients population.…”
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Does Academic Burnout Alleviate or Exacerbate Internet Dependence in University Students with Depression and Anxiety? by Jiang S, Jia Q, Peng Z, Zhou Q, Yi Q, An Z

“…This finding underscores the need for close monitoring of and intervention implementation for college students experiencing high levels of burnout and symptoms of depression or anxiety.Keywords: academic burnout, internet addiction, depression, anxiety, social support…”
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Methodological approaches for research of local market of IT services in the information space of region by I. V. Antokhonova, O. A. Polukhina, L. N. Saibonova

“…Limitation of data for research of information region space is compensated by development of the universal questionnaire and results of field inspection in the course of accomplishment of a grant of the Russian Foundation for Basic Research. The need for implementation of educational programs in the field of IT technologies for the population is revealed that can serve as a demand growth incentive in the local market of IT services.The practical importance of technique consists in reasons for approaches to regulation of the local market of IT services in the conditions of the current state of information region space.…”
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Is Internet access a unıque rıght, an element of the rıght to a dıgnıfıed lıfe, or a means that ensures the rıght to a dıgnıfıed lıfe? by M. S. Rahimova

“…Throughout the article, the author presents effective arguments for recognizing Internet access as a unique legal concept, removing it from the scope of being a means for the implementation of other fundamental human rights, changes to existing universal documents in this area, certain obligations of states in this direction and existing regulations, as well as the acceptance of the Internet as an integral element of the system of the right to a decent life. …”
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Photobiomodulation therapy at 650 nm enhances osteogenic differentiation of osteoporotic bone marrow mesenchymal stem cells through modulating autophagy by Haotian Li, Wenwen Yang, Biao Zhu, Miao Li, Xinran Zhang

“…The isolation and culture of OP-BMSCs were implemented after the establishment of the OP rat model. …”
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Social Aspects of Democratic Safeguards in Privacy Rights: A Qualitative Study of the European Union and China by Polonca Kovač, Grega Rudolf

“…Practical Implications: The article provides a concise overview of the relevant literature and an analysis of the rules that underpin the implementation, evaluation and improvement of regulations, especially in the light of ICT development, e.g. in times of the Covid-19 pandemic. …”
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Community engagement conduct for genetics and genomics research: a qualitative study of the experiences and perspectives of key stakeholders in Uganda by Harriet Nankya, Vincent P. Alibu, Enock Matovu, Edward Wamala, John Barugahare

“…The conduct of CE was reported to mainly occur at sample collection stage, rarely at study conception, and had not occurred at the return of results stage. Implementation of CE involved; engaging leaders first to gain access and acceptance of the research in the community; having a genetic counsellor on the CE team to handle the social issues in GGR. …”
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Effect of Training Program on Emotional Intelligence of Nurses Caring for Patients with Alzheimer’s Disease by Bahaa Ali, Omayma Osman, Ghada Mourad

“…Emotional intelligence comprises a deposit of interrelated skills involving a capability to appraise one's emotions and those of others, utilization and regulation of one's emotions, and social skills. …”
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FORMS OF IDENTIFYING AN ACTIVE PROFESSIONAL POSITION BY SPECIALISTS OF SERVICE SPHERE by Olena A. Ivanova

“…The features of communication activity in the professional position of a specialist in services include: social orientation, accessibility (participation in volunteer activities, grant programs), the ability to “sell themselves in the labor market”, the implementation of professional lifts. The understanding of the word “sell” in the indirect sense as the ability to talk about raising wages, salary; presentation of the value of their own time and professional resources to the employer; the ability to agree on improving the conditions of work comfort. …”
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Prediction of new candidate proteins and analysis of sub-modules and protein hubs associated with seed development in rice (Oryza sativa) using an ensemble network-based systems bi... by M. R. P. De Silva, J. W. J. K. Weeraman, S. Piyatissa, P. C. Fernando

“…This information is useful for achieving a systems biology understanding of seed development. This study implements an ensemble of algorithms for the analysis and showcases how systems biology techniques can be applied in developmental biology.…”
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Global legal anomie in the international legal system: general theoretical aspect by A. V. Malko, D. A. Lipinsky, R. S. Markunin, A. A. Ivanov

“…Global legal anomie is most clearly expressed: firstly, in the complete or partial absence of the necessary (conditionally new) norms of international law, secondly, in neglect of existing norms, and also, thirdly, in the massively deviating legal implementation activities of subjects of the world communities.…”
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On One Co-Integration Issue of Trade Links of Azerbaijan, Russia, Belarus and Kazakhstan by E. G. Orudzhev, S. M. Huseynova

“…The Johansen tests are implemented to find the cointegration area, after which the vector error correction model is built, which describes the long-term equilibrium relationship between the studied indicators and the path of returning to the equilibrium trajectory if it deviates from it. …”
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Human-augmented large language model-driven selection of glutathione peroxidase 4 as a candidate blood transcriptional biomarker for circulating erythroid cells by Bishesh Subba, Mohammed Toufiq, Fuadur Omi, Marina Yurieva, Taushif Khan, Darawan Rinchai, Karolina Palucka, Damien Chaussabel

“…Focusing on module M14.51 from the BloodGen3 repertoire, we implemented a multi-step LLM-driven workflow. Initial high-throughput screening used GPT-4, Claude 3, and Claude 3.5 Sonnet to score and rank the module’s constituent genes across six criteria. …”
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Role of microRNA modulation in the interferon-α/ribavirin suppression of HIV-1 in vivo. by Mohamed Abdel-Mohsen, Xutao Deng, Ali Danesh, Teri Liegler, Evan S Jacobs, Andri Rauch, Bruno Ledergerber, Philip J Norris, Huldrych F Günthard, Joseph K Wong, Satish K Pillai

“…<h4>Methods</h4>Global miRNA expression was examined in longitudinal PBMC samples obtained from seven HIV/HCV-coinfected, antiretroviral therapy-naïve individuals before, during, and after pegylated interferon-α/ribavirin therapy (IFN-α/RBV). We implemented novel hybrid computational-empirical approaches to characterize regulatory networks between miRNAs and anti-HIV-1 host restriction factors.…”
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Genome-wide identification and expression analysis of the Trihelix transcription factor family in potato (Solanum tuberosum L.) during development by Chao Mei, Yuwei Liu, Huiyang Song, Jinghao Li, Qianna Song, Yonghong Duan, Ruiyun Feng

“…Structural domain analysis revealed that motifs 1 and 2 may play a central role in the implementation of trihelix gene functions, and motifs 4 and 9 may be related to specific functions of StMSL. …”
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