Thrombotic Microangiopathy After Kidney Transplantation: Insights Into Genetic Etiology and Clinical Outcomes by Massini Merzkani, Nyein Chann Wai Lynn, Karen Flores, Gaurav Rajashekar, Kristin Progar, Rowena Delos Santos, John P. Atkinson, Daniel C. Brennan, Anuja Java

“…CNIs may exacerbate the risk of posttransplant TMA in the presence of other complement-activating factors. Our study also highlights the importance of personalized strategies and early interventions based on the functional assessment of variants of uncertain significance (VUS).…”
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SOLUBLE ADHESION MOLECULES IN CHILDREN WITH HEMOLYTIC UREMIC SYNDROME by T. E. Pankratenko, O. V. Moskalets, T. Yu. Abaseeva

“…Atypical hemolytic uremic syndrom (aHUS) is a rare severe life-threatening form of thrombotic microangiopathy. aHUS is thought to be primarily mediated by dysfunctional complement regulation, due to mutations or genetic rearrangement of the complement components, or regulatory factors, as well as autoantibody production to the complement factors. …”
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HIV treatment satisfaction: HIVTSQ-12 factor analysis and associated factors in Türkiye by Ilkay Akbulut, Zeynep Sedef Varol, Ilker Ödemiş, Emel Eroğul, Sabri Atalay, Ayşe Deniz Gökengin

“…Conclusion This study highlights the potential for personalizing HIV treatment strategies based on socio-demographic and clinical factors. Findings emphasize the need to promote healthy lifestyles, enhance health literacy, and implement anti-addiction programs to improve treatment adherence and satisfaction among PLWH. …”
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The role of inflammation in myopic retinopathy by Tianxiang Yang, Jinyan Qi, Jinyan Qi, Heping Xu, Heping Xu, Heping Xu

“…Locally, retinal homeostasis disruption triggers intraocular inflammation, evidenced by higher levels of interleukin-6 (IL−6), IL−8, tumor necrosis factor α (TNF−α), C-C motif chemokine ligand-2 (CCL2), C−X−C motif chemokine ligand 10 (CXCL10) and activating the complement system. …”
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Atypical hemolytic uremic syndrome: a case report and review of thrombotic mechanisms by George N. Zsidisin

“…Notably, a novel C3 defect, in addition to a common factor B mutation, leads to doubt over current theories of alternative complement overactivation and further drives focus onto the thrombotic nature of the disease. …”
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Exploring novel molecular mechanisms underlying recurrent pregnancy loss in decidual tissues by Hui Ding, Yajie Gao, Yuan Gao, Yulu Chen, Ruimin Liu, Caili Wang, Yuqing Gao

“…In vitro experiments evaluated the role of Complement Factor H-Related Protein 1 (CFHR1) in decidualization and the complement/coagulation pathways. …”
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Mesenchymal stromal cell secretome reduces lung injury and thrombo-inflammation induced by SARS-CoV-2 spike protein by Anna Pezzotta, Alessandra Bovio, Barbara Imberti, Monica Locatelli, Daniela Corna, Domenico Cerullo, Sara Gastoldi, Ariela Benigni, Giuseppe Remuzzi, Marina Morigi, Luca Perico

“…By preserving endothelial glycocalyx, CM reduced complement C3 accumulation, favoring factor H binding on the lung microvasculature. …”
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Iptacopan Reduces Proteinuria and Stabilizes Kidney Function in C3 Glomerulopathy by Carla M. Nester, Ute Eisenberger, Alexandre Karras, Moglie le Quintrec, Liz Lightstone, Manuel Praga, Giuseppe Remuzzi, Maria José Soler, Junhao Liu, Matthias Meier, Ronda Tawfik, Guido Junge, Andrea Biondani, Angelo J. Trapani, Nicholas J.A. Webb, Edwin K.S. Wong

“…Iptacopan (LNP023) is an oral, proximal complement inhibitor specifically targeting factor B, that selectively inhibits the alternative complement pathway. …”
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Legal regulation of the application of information management technologies (on the example of the transport industry) by E. Yu. Serbinenko, O. A. Dmitrieva

“…The article also suggests ways to effectively implement legal regulation.…”
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Oral glucose tolerance testing as a complement to fasting plasma glucose in screening for type 2 diabetes: population-based cross-sectional analyses of 146 000 health examinations... by Patrik Wennberg, Mattias Brunström, Anna Rosén, Julia Otten, Andreas Stomby, Simon Vallin

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C1Q Assay Results in Complement-Dependent Cytotoxicity Crossmatch Negative Renal Transplant Candidates with Donor-Specific Antibodies: High Specificity but Low Sensitivity When Pre... by José M. Arreola-Guerra, Natalia Castelán, Adrián de Santiago, Adriana Arvizu, Norma Gonzalez-Tableros, Mayra López, Isaac Salcedo, Mario Vilatobá, Julio Granados, Luis E. Morales-Buenrostro, Josefina Alberú

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Predictive Potential of CRTP5 and SII for Coronary Artery Severity and Myocardial Fibrosis in Patients with NSTE-ACS: An Exploratory Biomarker Study by Ji J, Qiao M, Ding Y, Wei X, Wan D, Wu L, Liu H

Subjects: “…Complement C1q tumor necrosis factor-related protein 5…”
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Sex-Related Differences in Chronic Pain: A Narrative Review by a Multidisciplinary Task Force by Maurizio Marchesini, Diego Fornasari, Silvia Natoli, Elena Vegni, Arturo Cuomo

“…These factors also affect sex-specific outcomes of analgesic treatments currently available. …”
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Pregnancy outcomes in C3 glomerulopathy: a retrospective review by Lauren O. Fergus, Meryl Waldman, Monica D. Hall, Lynn Vining, Jillian Hall, Tina Liu, Yuzhou Zhang, Patrick J. Walker, Richard J. H. Smith, Carla M. Nester

“…Twelve deliveries (44%) were premature, while 16 (59%) were associated with antepartum preeclampsia: an elevated risk when compared to healthy pregnancies and pregnancies of mothers with other glomerular diseases. Risk factors for complications included preexisting hypertension, an identified driver of complement dysregulation, and an eGFR prior to pregnancy of < 60 ml/min/1.73m2. …”
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Finerenone Alleviates Over-Activation of Complement C5a-C5aR1 Axis of Macrophages by Regulating G Protein Subunit Alpha i2 to Improve Diabetic Nephropathy by Zi-Han Li, Zi-Jun Sun, Sydney C. W. Tang, Ming-Hui Zhao, Min Chen, Dong-Yuan Chang

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C3 glomerulopathy in children: experience at a resource-limited center by Soumya Reddy, Abhishek Ghante, Mahesha Vankalakunti, Anil Vasudevan

“…However, diagnostic work-up in resource-limited settings is challenging because of the unavailability of complement assays and limited access to electron microscopy or genetic testing. …”
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Empowering service employees: A case study of banking industry by Hadi Moradi, Mohammad Reza Fallah

“…In addition, the implementation of Freedman test indicates that organizational based factors were number one priority on employee performance followed by job related factors and individual factors.…”
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LABOR PRODUCTIVITY AS A FACTOR OF by M. Uruymagov

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Production and social factors of economy by L. A. Akhmetov, D. A. Zuravlev

“…In article problems and questions of acceleration of growth of national economy, factors on ensuring increase of really located income of citizens of the country, decrease in level of poverty, realization of achievements of scientific and technical progress (the fourth industrial (industrial) revolution), implementation of some national projects are considered.…”
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On the concept and factors of the regional development by S. M. Khudoborodov, Ya. Yu. Radyukova

“…This raises an important issue in the formulation of the very concept of “development” and the factors that ensure it.Goal. The purpose of this study is to provide a tangible assessment of the category “regional economic development” and highlight the factors of its implementation.Materials and methods. …”
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