Development of a core patient-centred outcome set for adults living with obesity: a modified delphi-based international consensusResearch in context by Teferi Mekonnen, Leanne Staniford, Spencer Connell, Zofia Das-Gupta, Umanga DeSilva, Yasmine Saoud, Isabel Miller, Mohapradeep Mohan, Simon Nienhuijs, Megha Poddar, Vaishali Chetan Deshmukh, Marli Conradie-Smit, Soo Huat Teoh, Sanjeev Sockalingam, Emilia Huvinen, Paolo Sbraccia, Ronald Liem, Michael Vallis, Kenneth Clare, Tracy Zvenyach, Karen Coulman, Marianela Aguirre Ackermann, Verónica Vázquez-Velázquez, Yudith Preiss Contreras, Josep Vidal, Agbo Urudinachi, María Fernanda Tejeda-Muñoz, Ian Patton, T Alafia Samuels, Morgan Emile Gabriel Salmon Leguede, Georgia Rigas, Ximena Ramos Salas, Michael Crotty, Bruno Halpern, Daniel Bessesen, Laura Pizzi, Omniyat Mohammed Al Hajeri, Arya M. Sharma

“…Interpretation: Adoption of this standardised outcome set enables clinicians, patients, and stakeholders to identify care gaps, monitor outcomes, and evaluate the quality of obesity care against global benchmarks. Implementation can support the creation of a robust international data resource to guide research, inform clinical practice, and shape policy and guidelines for adult obesity treatment. …”
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Mitigation of chemotherapy-induced gut dysbiosis and diarrhea by supplementation with heat-killed Bacteroides fragilis by Xinwen Yan, Xinlong Lin, Jianhua Wu, Lijun Zheng, Yangyang Liu, Fang Wu, Ying Lin, Yishi Lu, Chongyang Huang, Binhai Shen, Hongbin Liu, Ruo Huang, Fengyi Hou, Qian Zhou, Mengyao Song, Ke Liu, Fangqing Zhu, Sheng Li, Yuqing Lin, Wei Wang, Ping Li, Wangjun Liao, Fachao Zhi

“…Mechanistic studies were conducted in murine models, complemented by IEC-6 cells and intestinal organoid experiments to elucidate microbiota-host interactions. …”
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Exome sequencing reveals low-frequency and rare variant contributions to multiple sclerosis susceptibility in Turkish families by Furkan Büyükgöl, Berk Gürdamar, Mehmet Ufuk Aluçlu, Yeşim Beckmann, Kaya Bilguvar, Cavit Boz, Alper Bülbül, Sena Destan Bünül, Özge Çetin, Caner Feyzi Demir, Serkan Demir, Taşkın Duman, Hüsnü Efendi, Özgül Ekmekçi, Utku Ertetik, Özlem Ethemoğlu, Elif Everest, Haluk Gümüş, Tuncay Gündüz, Rana Karabudak, Bedriye Karaman, Murat Kürtüncü, Muzaffer Mutluer, Meziyet Dilara Reda, Sabahattin Saip, Meral Seferoğlu, Elif Sever, Osman Ugur Sezerman, Sedat Şen, Beril Taşdelen, Mehmet Tecellioğlu, Murat Terzi, Aslı Tuncer, Ömer Faruk Turan, Melih Tütüncü, Gülgün Uncu, Uğur Uygunoğlu, Cihat Uzunköprü, Umut Voyvoda, Mehmet Fatih Yetkin, Nur Yüceyar, Aksel Siva, Eda Tahir Turanlı

“…To prioritize the genes and pathways that are potentially associated with MS, a segregation-based analysis of the variants was conducted and complemented by gene-based pathway enrichment analysis. …”
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A peer-support lifestyle intervention for preventing type 2 diabetes in India: A cluster-randomized controlled trial of the Kerala Diabetes Prevention Program. by Kavumpurathu R Thankappan, Thirunavukkarasu Sathish, Robyn J Tapp, Jonathan E Shaw, Mojtaba Lotfaliany, Rory Wolfe, Pilvikki Absetz, Elezebeth Mathews, Zahra Aziz, Emily D Williams, Edwin B Fisher, Paul Z Zimmet, Ajay Mahal, Sajitha Balachandran, Fabrizio D'Esposito, Priyanka Sajeev, Emma Thomas, Brian Oldenburg

“…Such strategies are not feasible for wider implementation in low- and middle-income countries (LMICs). …”
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ARTEMIS: An independently validated prognostic prediction model of breast cancer incorporating epigenetic biomarkers with main effects and gene-gene interactions by Maojie Xue, Ziang Xu, Xiang Wang, Jiajin Chen, Xinxin Kong, Shenxuan Zhou, Jiamin Wu, Yuhao Zhang, Yi Li, David C. Christiani, Feng Chen, Yang Zhao, Ruyang Zhang

“…ARTEMIS has superior performance compared to existing models in terms of accuracy, extrapolation, and sample size, as indicated by the systematic review. ARTEMIS is implemented as an interactive online tool available at http://bigdata.njmu.edu.cn/ARTEMIS/. …”
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Baseline variables associated with subsequent HIV seroconversion among gay, bisexual and other men who have sex with men and transgender women: a prospective, multicenter PrEP demo... by Carlos F. Caceres, Heather Pines, Kelika A. Konda, Annick Borquez, Ronaldo Moreira, Iuri Leite, Pedro Amparo, Marcelo Cunha, Thiago S. Torres, Juan V. Guanira, Jean-Pierre Jirón, Brenda Hoagland, Heleen Vermandere, Marcos Benedetti, Hamid Vega, Carlos M. Benites, Cristina Pimenta, Beatriz Grinztejn, Valdiléa Veloso, J. David Urbaez-Brito, Polyana d’Albuquerque, Claudio Palombo, Paulo Ricardo Alencastro, Raquel Keiko de Luca Ito, João L. Benedetti, Fabio V. Maria, Paula M. Luz, Lucilene Freitas, Kim Geraldo, Monica Derrico, Sandro Nazer, Tania Kristic, Renato Girade, Renato Lima, Antônio R. Carvalho, Carla Rocha, Pedro Leite, Marcio Lessa, Marilia Santini-Oliveira, Daniel R.B. Bezerra, Cleo de Oliveira Souza, Jacinto Corrêa, Marcelo Alves, Carolina Souza, Camilla Portugal, Mônica dos Santos Valões, Gabriel Lima Mota, Joyce Alves Gomes, Cynthia Ferreira Lima Falcão, Fernanda Falcão Riberson, Luciano Melo, Talita Andrade Oliveira, Agnaldo Moreira Oliveira Júnior, Bruna Fonseca, Leonor Henriette Lannoy, Ludymilla Anderson Santiago Carlos, João Paulo Cunha, Sonia Maria de Alencastro Coracini, Thiago Oliveira Rodrigues, Emília Regina Scharf Mettrau, Kelly Vieira Meira, Heder Tavares, Ana Paula Nunes Viveiros Valeiras, Taiane Miyake Alves de Carvalho Rocha, Alex Amorim, Patrícia Sabadini, Luiz Gustavo Córdoba, Caio Gusmão, Erika Faustino, Julia Soares da Silva Hansen, Agatha Mirian Cunha, Neuza Uchiyama Nishimura, Jaime Eduardo Flygare Razo Prereira Santos, Aline Barnabé Cano, Willyam Magnum Telles Dias, Magô Tonhon, Tania Regina Rezende, Alex Gomes, Eloá dos Santos Rodrigues, Maria das Dores Aires Carneiro, Alexandre Castilho, Mariana Carvalho, Dulce Diaz-Sosa, Centli Guillen-Diaz-Barriga, Lorena Hernández, Rebeca Robles, Maria Elena Medina-Mora, Marcela González, Ivonne Huerta Icelo, Araczy Martinez Davalos, José Gomez Castro, Luis Obed Ocampo Valdez, Fernanda Ramírez Barajas, Verónica Ruiz González, Galileo Vargas Guadarrama, Israel Macías, Jehovani Tena Sánchez, Juan Pablo Osuna Noriega, H. Rodrigo Moheno M, Jorge M. Bernal Ramírez, Víctor Dante Galicia Juarez, Gerardo Vizcaíno, Francisco Javier Arjona, Gino Calvo, Silver Vargas, Oliver Elorreaga, Ximena Gutierrez, Fernando Olivos, Damaris Caviedes, Daniella Adriazola, Eduardo Juárez, Gabriela Mariño, Jazmin Qquellon, Francesca Vasquez, Jean Pierre Jiron, Sonia Flores, Karen Campos

“…Summary: Background: Ongoing implementation of HIV pre-exposure prophylaxis (PrEP) in Latin America should consider lessons learned from implementation projects such as ImPrEP (Brazil/Mexico/Peru, 2018–2021). …”
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Energy renovation rates in the Netherlands – comparing long and short term prediction methods by Faidra Filippidou, Nina Holck Sandberg, Igor Sartori, Nico Nieboer, Magnus Inderberg Vestrum, Jan Sandstad Næss, Helge Brattebø

“…Information about the progress of energy performance renovations is necessary to track the progress of policy implementation and its effectiveness. Moreover, advanced quality information and data are needed to help develop roadmaps and future policies resulting in energy efficient buildings. …”
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Control Shift by Theodora Chatzi Rodopoulou

“…This framework is capable of practical implementation and can contribute to an enhanced, more responsive, more sustainable, more inclusive, more value-driven and more holistic practice. …”
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The OPTION trial: outpatient induction of labour – study protocol for a prospective, non-inferiority, multicentre randomised controlled trial by Kristina Gemzell-Danielsson, Susanne Hesselman, Sophia Brismar Wendel, Magnus Domellöf, Ulla-Britt Wennerholm, Maria Jonsson, Verena Sengpiel, Helen Elden, Ylva Carlsson, Sofie Graner, Tove Wallström, Helena Kopp-Kallner, Heléne Sangskär, Andreas Herbst

“…The study will involve more than 80% of all delivery units in Sweden, which will allow for a smooth implementation of any new routine after the study’s conclusion. …”
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High data retrieval rates with SwissPedData for paediatric traumatic brain injuries in children’s hospitals: a multicentre, point-prevalence study by Michael von Rhein, Niklaus Krayenbühl, Andreas Meyer-Heim, Sergio Manzano, Gianluca Gualco, Renato Gualtieri, Fabrizio Romano, Alexander Mack, Larissa Hauser-Angst, Michelle Seiler

“…This study evaluates the preparedness of the ten SwissPedNet hospitals for SwissPedData before its nationwide implementation, focusing on: (a) whether the defined common data elements are effectively documented and can be retrieved for children presenting with traumatic brain injuries to paediatric emergency departments, and (b) analysis of the content of these common data elements to assess how children with traumatic brain injuries are treated in paediatric emergency departments across Switzerland. …”
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Evaluation Indicators of Science, Technology, and Innovation: A Comparative Study of Iran, Australia, and New Zealand by Leila Namdarian

“…Furthermore, the study adopts an interdisciplinary approach, incorporating insights from science policy, economics, and innovation studies to enrich the comparative analysis.Findings: The findings reveal significant differences in the prioritization and implementation of STI evaluation indicators across the three countries. …”
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Post-abortion family planning use and its determinants among women who received abortion care in sub-Saharan Africa: a systematic review and meta-analysis by Berihun Agegn Mengistie, Saron Abeje Abiy, Tazeb Alemu Anteneh, Solomon Berhe Wubneh, Fantahun Andualem, Mihret Melese, Elsa Awoke Fentie, Abebaw Setegn, Muluken Demeke, Gebeyehu Nigussie Amare, Gashaw Worku, Gizachew Aynalem Tegegne, Tilahun Nega Godana, Wondimnew Mersha Biset, Nuhamin Tesfa Tsega, Getie Mihret Aragaw

“…Therefore, appropriate planning and implementation of effective strategies are crucial to scaling up post-abortion family planning use, including improving educational attainment, advocating for post-abortion contraceptive methods, and providing effective post-abortion family planning counseling. …”
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Associations Among Skeletal Muscle Health, Disability, and Self-Reported Physical Function in Survivors of Critical IllnessTake-Home Points by Kimberly F. Rengel, MD, MSCI, Jo Ellen Wilson, MD, MPH, PhD, Heidi J. Silver, RD, PhD, Emma Hollingsworth, MPH, Onur M. Orun, MS, James C. Jackson, PsyD, Matthew F. Mart, MD, Christopher G. Hughes, MD, E. Wesley Ely, MD, MPH, Nathan E. Brummel, MD, MSCI, ATSF

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Accumulation Differences in Perfluorooctanoic Acid and Its Ether Carboxylic Acid Alternatives in the Manila Clam (Ruditapes philippinarum) by Hanlin QIN, Yujie BI, Shuqi JIANG, Chengchen WU, Zhijun TAN, Qianqian GENG, Mengmeng GUO

“…Consequently, several countries and organizations have implemented strict restrictions or controls on its use. …”
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Modeling the construction of an efficient customer club for the quantitative and qualitative development of increasing customers in the banking system by Ali Taher khani kojariha, Younos Vakil Alroaia

“…According to its purpose, the research method is a\applicable; and in terms of implementation method, it is mixed (qualitative-quantitative); and exploratory in terms of the research implementation strategy. …”
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Cytomegalovirus Reactivation Is Associated With Lower Rates of Hepatocellular Carcinoma Recurrence After Liver Transplantation by Victoria Aguilera, Sarai Romero Moreno, Isabel Conde, Angel Rubín, Angela Carvalho-Gomes, Mario Romero, Javier Zamora-Olaya, Miguel Angel Gómez-Bravo, Esteban Fuentes-Valenzuela, Cristina Dopazo, Nikita Bilbao, Antonio González, Ana Sánchez-Martínez, Sonia Pascual, Jesús Rivera-Esteban, José Ignacio Herrero, Sara Lorente, Antonio Cuadrado-Lavín, Flor Nogueras, Laura Martínez-Arenas, Rocío González-Grande, Marina Berenguer, Manuel Rodriguez-Perálvarez

“…CMV prophylaxis was implemented for 19.7% of patients, while the rest were managed with preemptive therapy. …”
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Internet and telephone intervention to support patients discontinuing long-term antidepressants in primary care: the REDUCE research programme including RCT by Tony Kendrick, Beth Stuart, Hannah Bowers, Mahboobeh Haji Sadeghi, Helen Page, Christopher Dowrick, Michael Moore, Mark Gabbay, Geraldine Leydon, Guiqing Lily Yao, Shihua Zhu, Paul Little, Gareth Griffiths, Glyn Lewis, Carl May, Joanna Moncrieff, Chris F Johnson, Una Macleod, Simon Gilbody, Rachel Dewar-Haggart, Samantha Williams, Wendy O’Brien, Riya Tiwari, Catherine Woods, Tasneem Patel, Naila Khan, Emma Maund, Nadja van Ginneken, Amy Din, Claire Reidy, Rebecca Lucier, Bryan Palmer, Taeko Becque, Yumna Masood, Natalie Thompson, Ellen van Leeuwen, Marta Glowacka, Adam WA Geraghty

“…Objectives To conduct a systematic review of quantitative and qualitative literature, to identify interventions that have been used to help patients withdraw from antidepressant treatment. To identify factors that promote or inhibit the implementation of treatment withdrawal, through interviews with patients taking them long term, and focus groups with GPs, nurse practitioners (NPs) and primary care mental health workers who treat patients. …”
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A personalised health intervention to maintain independence in older people with mild frailty: a process evaluation within the HomeHealth RCT by Rachael Frost, Yolanda Barrado-Martín, Louise Marston, Shengning Pan, Jessica Catchpole, Tasmin Rookes, Sarah Gibson, Jane Hopkins, Farah Mahmood, Benjamin Gardner, Rebecca L Gould, Claire Jowett, Rashmi Kumar, Rekha Elaswarapu, Christina Avgerinou, Paul Chadwick, Kalpa Kharicha, Vari M Drennan, Kate Walters

“…Conclusions HomeHealth represents an acceptable and implementable intervention for older people with mild frailty but may work via different mechanisms than those intended. …”
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Perceptions of pancreatic surgeons and the current status of palliative care for pancreatic cancer in China: a multi-center online questionnaire survey by Qiaofei Liu, Yuze Hua, Jishu Wei, Qi Zhang, Zheng Wang, Xiaodong Tian, Feng Cao, Hanxiang Zhan, Song Gao, Shixiang Guo, Rongui Lin, Jinyong Xu, Shanmiao Gou, Chunlu Tan, Yuan Ding, Shi Si, Jiabin Jin, Zipeng Lu, Lei Cai, Min Wang, Chen Hua, Bin Zhou, Lei Zhang, Xiaohong Ning, Wenming Wu

“…The top 3 advice from the surgeons to promote palliative care were more education and training, seminars, and public broadcasting. 69.9% of the surgeons have concerns about the legal issue of implementation of palliative care. Conclusion:. In general, the majority of pancreatic surgeons in China lack training and experience in palliative care for pancreatic cancer, and the current status of palliative care in most hospitals needs to be further improved. …”
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Designing a comprehensive behaviour change intervention to promote and monitor exclusive use of liquefied petroleum gas stoves for the Household Air Pollution Intervention Network... by J Jaime Miranda, William Checkley, Kyle Steenland, Vanessa Burrowes, Kirk R Smith, Aris Papageorghiou, Abigail Jones, Ghislaine Rosa, Anaité Díaz-Artiga, Gurusamy Thangavel, Kalpana Balakrishnan, Joshua P Rosenthal, Thomas F Clasen, Steven A Harvey, Amit Verma, Kendra N. Williams, Lisa M. Thompson, Zoe Sakas, Mayari Hengstermann, Ashlinn Quinn, Elisa Puzzolo, Jennifer Peel, Vigneswari Aravindalochanan, Dana Boyd Barr, Alejandra Bussalleu, Devan Campbell, Eduardo Canuz, Adly Castañaza, Howard Chang, Yunyun Chen, Marilú Chiang, Maggie L Clark, Rachel Craik, Mary Crocker, Victor Davila-Roman, Lisa de las Fuentes, Oscar De León, Ephrem Dusabimana, Lisa Elon, Juan Gabriel Espinoza, Irma Sayury Pineda Fuentes, Sarada Garg, Dina Goodman, Savannah Gupton, Meghan Hardison, Stella Hartinger, Phabiola M Herrera, Shakir Hossen, Penelope Howards, Lindsay Jaacks, Shirin Jabbarzadeh, Michael A Johnson, Katherine Kearns, Miles Kirby, Jacob Kremer, Margaret A Laws, Pattie Lenzen, Jiawen Liao, Amy E Lovvorn, Fiona Majorin, Eric McCollum, John McCracken, Julia N McPeek, Rachel Meyers, Erick Mollinedo, Lawrence Moulton, Krishnendu Mukhopadhyay, Luke Naeher, Abidan Nambajimana, Durairaj Natesan, Florien Ndagijimana, Azhar Nizam, Jean de Dieu Ntivuguruzwa, Ricardo Piedrahita, Ajay Pillarisetti, Naveen Puttaswamy, Sarah Rajkumar, Usha Ramakrishnan, Rengaraj Ramasami, Davis Reardon, Barry Ryan, Sudhakar Saidam, Sankar Sambandam, Jeremy A Sarnat, Suzanne Simkovich, Sheela S Sinharoy, Damien Swearing, Ashley Toenjes, Lindsay Underhill, Jean Damascene Uwizeyimana, Viviane Valdes, Kayla Valentine, Lance Waller, Megan Warnock, Wenlu Ye, Bonnie Young

“…We conducted theory-grounded formative research to identify contextual factors influencing cooking fuel choice to guide the development of behavioural strategies for the Household Air Pollution Intervention Network (HAPIN) trial. …”
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