Does the island area also need to insist on salt iodization to prevent iodine deficiency disorders? a cross-sectional survey in Hainan Province, China by Hongying Wu, Shizhu Meng, Dingwei Sun, Yuting Hu, Tingou Wu, Xiaohuan Wang, Xingren Wang, Ying Liu, Chuyan Peng, Chuyan Peng, Bin He, Fangang Meng, Fangang Meng

“…To provide a basis for the effective implementation of scientific iodine supplement prevention and control strategy.MethodsAll 21 cities, counties (districts) in the province were investigated. …”
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Pembrolizumab versus sintilimab in patients with advanced NSCLC: a retrospective multicenter study with propensity-score matching analysis by Zhengzheng Xia, Juan Hong, Xiangyang Yu, Yuhua Ran, Huali Xie, Ziyuan Zhou, Jing Zuo, Tujia Chen, Jun Meng, Jun Yang

“…A multicenter retrospective cohort study was designed and implemented using propensity-score matching (PSM) analysis to compare the effectiveness and safety profiles of pembrolizumab and sintilimab in patients with advanced NSCLC undergoing comprehensive therapy.MethodsA total of 225 patients who received comprehensive therapy including pembrolizumab (n = 127) or sintilimab (n = 98), from 1 January to 31 December 2020 and met the eligibility criteria were included. …”
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Development of a predictive model for long-term care and support eligibility certification associated with dementia-related functional impairments: the IRIDE cohort study by Daichi Yamashiro, Hiroyuki Suzuki, Susumu Ogawa, Mari Yamashita, Hiroki Moriya, Hiroyuki Sasai, Shuichi P. Obuchi, Takumi Abe, Hiroshi Murayama, Takumi Hirata, Yoshinori Fujiwara, Shuichi Awata, Masahiro Akishita, Kenji Toba, IRIDE Cohort Study Investigators

“…Two models were developed: Model 1, focused on dementia-related functional impairments factors in Japan, whereas Model 2, prioritized social implementation by limiting predictors to self-reportable items. …”
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High heterogeneity of cross-reactive immunoglobulins in multiple sclerosis presumes combining of B-cell epitopes for diagnostics: a case-control study by Leyla A. Ovchinnikova, Igor E. Eliseev, Igor E. Eliseev, Samir S. Dzhelad, Taras O. Simaniv, Ksenia M. Klimina, Maria Ivanova, Elena N. Ilina, Maria N. Zakharova, Sergey N. Illarioshkin, Yury P. Rubtsov, Alexander G. Gabibov, Alexander G. Gabibov, Alexander G. Gabibov, Yakov A. Lomakin

“…We concluded that the combination of particular peptides from SPTAN1, PTK6, PRX and LMP1 could be implemented as a four-peptide biomarker panel for MS diagnosis (area under the curve (AUC) of 0.818 for discriminating between HD and MS).ConclusionsThis study supports the concept that the specificity of autoreactive IgG in MS is highly heterogeneous. …”
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Socio-economic contextual determinants and behavioral changes during pregnancy: evidence from the "MAMI-MED" cohort by Francesca Bitonti, Angelo Mazza, Martina Barchitta, Andrea Maugeri, Roberta Magnano San Lio, Giuliana Favara, Claudia La Mastra, Maria Clara La Rosa, Fabiola Galvani, Elisa Pappalardo, Carla Ettore, Giuseppe Ettore, Federico Mertoli, Carmela Elita Schillaci, Antonella Agodi

“…Mann–Whitney test, Kruskal–Wallis tests, logistic regressions and mixtures of regressions models with concomitant variables are implemented 1) to investigate the associations between contextual covariates and individual responses, 2) to assess the presence of latent sub-groups of the population reacting differently to the same contextual factors. …”
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Engaging the private sector as part of HIV pre-exposure prophylaxis service delivery in Vietnam: a comparative analysis of uptake, persistence and HIV seroconversion from 2018 to 2... by Bao Ngoc Vu, Kimberly Green, Huong Phan, Long Tran, Phuong Phan, Tham Tran, Linh Doan, Yen Vu, Chau Pham, Dao Nguyen, Anh Doan, Trang Ngo, Phuong Tran, Vuong Nguyen, Bieu Nguyen, Thai Phan, Ha Nguyen

“…We assessed the effectiveness of this approach to inform ongoing efforts to accelerate epidemic control by 2030.MethodsWe implemented a process evaluation with longitudinal design using retrospective programmatic data collected and uploaded onto a secure online system (HMED) from 23 public and 17 private PrEP clinics in Hanoi, Ho Chi Minh City (HCMC), and Dong Nai. …”
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Pediatric cardiac surgical site infections: A single-center quality improvement initiativeCentral MessagePerspective by Nhat Chau, HBSc, Crystal Tran, HBSc, CCRP, Megan Clarke, MN, RN, CIC, Jennifer Kilburn, MN, RN, Cecilia St. George-Hyslop, MEd, RN, CNCCPC, Diana Young, RN, Sandra L. Merklinger, MN-NP, PhD, Erica Mosolanczki, MN-NP, Vivian Trinder, MN-NP, Jill O'Hare, MN-NP, Karen Clarke, RN, Kate McCormick, MScN, RN, Rachel D. Vanderlaan, MD, PhD, FRCSC

“…Therefore, as a quality improvement initiative, we implemented interventions with the goal of decreasing SSI rates by 30%. …”
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Strengthening open disclosure in maternity services in the English NHS: the DISCERN realist evaluation study by Mary Adams, Natalie Sanford, Charlotte Bevan, Maria Booker, Julie Hartley, Alexander Heazell, Elsa Montgomery, Maureen Treadwell, Jane Sandall

“…We found PMRT implementation sometimes lacked relational care for families. …”
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Integrated transportation system planning with gravitational search algorithm approach based on fuzzy mutant controller by Alireza Hosseinzadeh Kashani, Seyed Ahmad Shayannia, Mohammad Mehdi Movahedi, Soheila Sardar

“…In another study, entitled "Analysis of the Role of Financial Factors in the Whiplash Effect in a Two-tier Supply Chain”, Movahedi, Zulfaqari and Jolai, paid attention to the financial factors affecting the escalation of the whiplash effect and quantified this effect. …”
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Impacts of parental genomic divergence in non-syntenic regions on cotton heterosis by Chujun Huang, Yu Cheng, Yan Hu, Xuemei Zhang, Jinwen Chen, Ting Zhao, Zhanfeng Si, Yiwen Cao, Yiqian Li, Lei Fang, Xueying Guan, Tianzhen Zhang

“…Conclusion: Our study clarified non-syntenic regions to harbor more loci with higher heterotic effects, revealed their importance in promoting heterosis and supported the crucial role of genetic complementation in heterosis. SVs and introgressions were identified as key factors responsible for non-syntenic divergence between the parents. …”
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CuddleCard: Protocol for a randomized controlled trial evaluating the effect of providing financial support to low-income mothers of preterm infants on parental caregiving in the n... by Margaret McConnell, Alya Alsager, Plyce Fuchu, Shrivaths Sriprasad, Lindsey Simoncini, Mari-Lynn Drainoni, Erika G. Cordova-Ramos, Michelle-Marie Peña, Laura Madore, Nikita S. Kalluri, Michael Silverstein, Heather Schofield, Martha J. Farah, Günther Fink, Margaret G. Parker

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Cognitive-bias modification intervention to improve physical activity in patients following a rehabilitation programme: protocol for the randomised controlled IMPACT trial by Stéphane Cullati, Axel Finckh, Delphine S Courvoisier, Boris Cheval, Matthieu P Boisgontier, Reinout W Wiers, Silvio Maltagliati, Layan Fessler, David Sander, Malte Friese, Christophe Luthy

“…However, the implementation and evaluation of intervention designed to change these automatic bases of PA are rare. …”
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GENDER PECULIARITIES OF THE SPECTRUM OF CHROMOSOMAL ABERRATIONS IN PERIPHERAL BLOOD LYMPHOCYTES OF HEALTHY PERSONS AND PATIENTS WITH GENERALIZED PERIODONTITIS by M. I. Khomyk, L. Ye. Kovalchuk, H. M. Melnychuk

“…The presence of dicentric chromosomes (dicentrics) in patients with GP of II-III degree of men and women showed instability of the genotype, which caused the violation of the implementation of genetic information. An increase in the number of CA in the GP may indicate a slight weakening of the protective forces of the patients’ bodies, because this precludes the elimination of cells with a broken genetic apparatus. …”
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Building Epidemiological Capacity for Health Security in Liberia by Muhammad Shakir Balogun, Maame Amo Addae, Himiede Wede Wilson

“…The first paper in this supplement is a report of the implementation of this critical capacity building and health systems strengthening effort. …”
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PSYCHOANALYTIC DIMENSIONS OF IVAN FRANKO’S GREAT PROSE OF 1887–1893 by Svitlana M. Lutsak, Nataliia M. Vivcharyk

“…The following tasks arise from the objective: To analyze the key vectors of the twin myth in the novel “Lel and Polel”; characterize the ambivalent manifestations of the Great Mother archetype in the image of the main heroine in the novel “For the Home Hearth”; identify transformations of Freudian ideas in the artistic structure of the novel “Foundations of Society”, considering their animistic component. The implementation of the set tasks necessitated the use of such methods as receptive-interpretative, psychoanalytic, mythopoetic, hermeneutic, and biographical. …”
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Current Enzooticity of <i>Dirofilaria immitis</i> and <i>Angiostrongylus vasorum</i> in Central and Southern Italy by Donato Traversa, Simone Morelli, Angela Di Cesare, Chiara Astuti, Alessandra Barlaam, Mariasole Colombo, Fabrizia Veronesi, Barbara Paoletti, Raffaella Iorio, Raffaella Maggi, Alessandra Passarelli, Alessia Pede, Linda Rossi, Manuela Diaferia

“…A high level of vigilance and routine parasitological screening are necessary, considering the high prevalence of intestinal parasites in owned dogs that are also co-infected by respiratory parasites. The implementation of chemoprevention against <i>D. immitis</i> in dogs living in the examined area should be encouraged.…”
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Evaluating the Influence of Different Artificial Diets on <i>Apis mellifera</i> L. Using Health Biomarkers and Performance Metrics by Shams Ul Islam, Muhammad Anjum Aqueel, Muhammad Usman Yousuf, Asim Abbasi, Muhammad Yasin, Rashid Iqbal, Muhammad Fahim Raza, Aqsa Parvaiz, Nazih Y. Rebouh

“…Numerous diets have been developed; however, their global implementation faces challenges due to diverse climatic conditions and some other factors. …”
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Post-pandemic upsurge in Group A Streptococcus infections at an Italian tertiary university hospital by Gabriele Arcari, Federica Novazzi, Lorenzo Colombini, Francesca Drago Ferrante, Sara Boutahar, Angelo Paolo Genoni, Gianluca Cassani, Paolo Gigante, Mattia Carbotti, Alessandro Bianco, Mariana Tirziu, Riccardo Capuano, Renee Pasciuta, Francesco Iannelli, Nicola Clementi, Francesco Santoro, Nicasio Mancini

“…Following the loosening of various public health measures implemented to face the challenge of the COVID-19 pandemic, a significant rise in GAS cases has been observed. …”
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Paradigms of the agricultural system in times of COVID-19 by Luis Edgar Blanco-Capia

“…It is time to reflect, change the model and paradigm1, planning structural policies in the food industry that allow the implementation of digital solutions, with the aim of promoting productive development10. …”
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Gestão de risco e as estratégias do plano de contingência para COVID-19 [COVID-19 contingency plan strategies and risk management] [Gestión de riesgos y estratégias del plan de con... by Pedro Ruiz Barbosa Nassar, Érica Brandão Moraes, Deise Ferreira Souza, André Luiz de Souza Braga, Bárbara Pompeu Christovam, Mercedes Neto

“…Method: in this executive evaluation study, the analysis followed the steps: policy description; problem diagnosis; policy design; implementation; governance; results and impacts; to establish an overall panorama of the National Human Infection Contingency Plan for the new Coronavirus. …”
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