Non-healthcare system interventions and COVID-19 daily cases: a multilevel time series analysis by Hao Ma, Lei Lei, Aonan Liu, Yanfang Yang

“…To analyze the effects of national, regional, and income group factors on the number of daily new COVID-19 cases, we implemented three multilevel sequential mixed-effects models and applied restricted maximum likelihood to estimate the variance of random effects. …”
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The socio-technical adoption and diffusion of digital health innovations: The development of the STAD-HC model based on telemedicine in Germany by Yvonne Rauner, Harald Stummer

“…While the Diffusion of Innovations (DOI) theory explains staged adoption processes, it underrepresents socio-political and institutional factors. The Social Shaping of Technology (SST) approach complements DOI by focusing on the co-construction of technology through cultural, organizational, and political dynamics. …”
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On the strategy of prevention and protection against discrimination as the basic document of the state’s anti-discrimination policy by Mršević Zorica

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Cognitive dynamics in teacher knowledge development through lesson study: Insights from two Chinese teams by Haiyan Xu, Chris Wilkins

“…The study highlights the complexities of curriculum implementation at the classroom level as teachers can hold a diverse range of practical conceptions close to or distant from new curriculum ideals. …”
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Implementation of a Highly-Sensitive and Wide-Range Frequency Measurement Using a Si₃N₄ MDR-Based Optoelectronic Oscillator by Pengcheng Liu, Pengfei Zheng, Dongdong Lin, Jing Li, Xuemeng Xu, Guohua Hu, Binfeng Yun, Yiping Cui

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Analysis of the Ukrainian legislation on labour protection adaptation to the European Union acts by S. A. Petrovska, M. V. Petrovskyi

“…On the basis of the study, there have been identified factors that negatively affect the implementation process. …”
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Correlation between serum level of complement C3 and abdominal aortic calcification in maintenance hemodialysis patients by Zhao Xin, Bi Chun-sheng

“…Objective To explore the correlation between serum level of complement C3 and abdominal aortic calcification（AAC）in maintenance hemodialysis（MHD）patients.Methods A total of 127 MHD patients hospitalized between February 2019 and December 2019 were selected.Based upon to the points of AACs, they were divided into the groups of non-calcification（AACs<1,n=31）,mild calcification（1≤AACs<5,n=36）,moderate calcification（5≤AACs≤15,n=32）and severe calcification（AACs>15,n=28）.The relevant clinical data were collected and serum level of complement C3 was detected.The difference of serum complement C3 level with different degree of calcification and its correlation with AAC were analyzed.The influencing factors of AAC were analyzed by Logistic regression.The predictive value of serum level of complement C3 for AAC was analyzed by plotting the curve of receiver operating characteristic（ROC）.Results The levels of serum phosphorus, intact parathyroid hormone（iPTH）and complement C3 were significantly higher in mild/moderate/severe calcification group than those in non-calcification group（P<0.05）;levels of serum phosphorus, iPTH and complement C3 significantly higher in moderate/severe calcification group than those in mild calcification group（P<0.05）;the levels of serum phosphorus, iPTH and complement C3 significantly higher in severe calcification group than those in moderate calcification group（P<0.05）.Serum level of complement C3 was positively correlated with serum phosphorus, iPTH and AACs points（P<0.05）.And serum levels of phosphorus, iPTH and complement C3 were independent risk factors of AAC（P<0.05）.And the area under curve（AUC）of serum complement C3 was 0.858 for predicting AAC（P<0.05）.Conclusion Serum level of complement C3 is associated with the severity of AAC.As one of the independent risk factors for AAC,it may become an important biological marker for predicting the occurrence of AAC in MHD patients.…”
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Health promotion for blood donors: A scoping review by Linda J.H. Marx, Suzanna M. Van Walraven, Ruben van Zelm, Barbara Sassen

“…Conclusion: This review highlights the implementation of health initiatives by blood banks, focusing on improving well-being and preventing diseases. …”
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Evaluating blockchain technology for contract farming in tanzania: A task-technology fit analysis by Cesilia Mambile, Hilda Abraham Mwangakala, Frederick Chali, Bernard Julius, Deo Shao, Hector Mongi, Fredrick Ishengoma

“…Data collection involved structured surveys, in-depth interviews, and focus group discussions, analyzed through the TTF framework to assess technology-task alignment and implementation factors. Results reveal strong technology-task fit in contract creation (9/10), payment processing (9/10) and record-keeping (9/10), with blockchain’s smart contracts and immutable ledger capabilities effectively addressing current operational inefficiencies. …”
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Characterizing HIV seroconversions among a cohort of oral PrEP users in South Africa by Catherine E. Martin, Hlologelo Ramatsoma, Glory Chidumwa, Laura Ashleigh Cox, Saiqa Mullick

“…Methods This paper documents ctra series of seroconversions within a large implementation study conducted in eight Department of Health facilities and four linked mobile clinics in four areas of South Africa. …”
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Integrating postnatal care into the redesign of group care beyond birth by Ashley Gresh, Astrid Van Damme, Deborah L. Billings, Sharon Schindler Rising, Shaimaa Ibrahim, Abiola Ajibola, Ellen Chirwa, Jennyfer Don-Aki, Nastassia Donoho, Manodj Hindori, Nafisa Jiddawi, Emeka Kanebi, Esnath Kapito, Catherine Kay, Tara Kinra, Vlorian Molliqaj, Bolanle Oyeledun, Marlies E. B. Rijnders, Octavia Wiseman, Ghutai Sadeq Yaqubi, Crystal L. Patil

“…A constellation of health system and social factors contribute to this, including poor quality and barriers to accessing health care, including preventive services. …”
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Increased Autoreactivity of the Complement-Activating Molecule Mannan-Binding Lectin in a Type 1 Diabetes Model by Jakob Appel Østergaard, Marieta Milkova Ruseva, Talat Habib Malik, Ingeborg Torp Hoffmann-Petersen, Matthew Caleb Pickering, Steffen Thiel, Troels Krarup Hansen

“…Diabetes and control groups did not differ in glomerular immunofluorescence intensity obtained by antibodies against complement factors C4, C3, and C9. However, the circulating complement activation product C3a was increased in diabetes as compared to control mice (P=0.04). …”
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Process evaluation of a co-designed best practice model of dementia care in Aboriginal and Torres Strait Islander primary care: The Let's CHAT (Community Health Approaches To) Deme... by Kate Bradley, Jo-anne Hughson, Irene Blackberry, Lauren Poulos, Kylie Sullivan, Naomi Paine, Roslyn Malay, Diane Cadet-James, Harold Douglas, Bridget Allen, Bonnie Martin-Giles, Kate Fulford, Sadia Rind, Wendy Allan, Janaya Charles, Juliette Ciaccia, Kylie Radford, Robyn Smith, Dina LoGiudice

“…Utilising the integrated-Promoting Action on Research Implementation in Health Services (i-PARIHS) Framework, the process evaluation aimed to identify the components of a “successful implementation” for this type of intervention. …”
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Visualizing interactions along the Escherichia coli twin-arginine translocation pathway using protein fragment complementation. by Jan S Kostecki, Haiming Li, Raymond J Turner, Matthew P DeLisa

“…To visualize these interactions, we have adapted bimolecular fluorescence complementation (BiFC) to detect protein-protein interactions along the Tat pathway of living cells. …”
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Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective by Didar Murad, Rehan Zafar Paracha, Maryum Nisar

“…Simulation results highlight key components affected, including thrombin, tissue plasminogen activator, plasmin, fibrin degradation products, interleukin 6 (IL-6), the IL-6 and IL-6R complex, and the terminal complement complex (C5b-9). We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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Bead arrays for antibody and complement profiling reveal joint contribution of antibody isotypes to C3 deposition. by Burcu Ayoglu, Eszter Szarka, Krisztina Huber, Anita Orosz, Fruzsina Babos, Anna Magyar, Ferenc Hudecz, Bernadette Rojkovich, Tamás Gáti, György Nagy, Jochen M Schwenk, Gabriella Sármay, József Prechl, Peter Nilsson, Krisztián Papp

“…Here, we present a bead array-based assay for a multiplexed determination of antigen-specific antibody levels in parallel with their properties for complement activation. We measured the deposition of C3 fragments from serum samples to reflect the degree of complement activation via all three complement activation pathways. …”
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Plasma complement proteins as biomarkers and therapeutic targets in chronic kidney disease: a Mendelian randomization analysis by Yu-Peng Xu, Zheng-Qi Song, Ming-Li Chen, Yang-Li Fang, Hui-Di Zhang

“…This study investigates the causal role of diverse plasma complement proteins in CKD and its clinical types to discover new biomarkers and therapeutic targets.Method Using two-sample Mendelian randomization (MR), we examined the causal relationships between 28 plasma complement proteins and CKD outcomes. …”
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Systematic Review of the Link Between Oxford MEST-C Classification and Complement Activation in IgA Nephropathy by Gabriel Ștefan, Eric Alamartine, Christophe Mariat, Nicolas Maillard

“…C4d, C3, C5b9, MBL, C4, and factor H-related protein 5 (FHR5) were the most frequently studied complement proteins in relation to the MEST-C classification. …”
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Experiences of school health professionals in implementing structured assessments of sexual health and experiences of violence among youth in Sweden using the SEXual health Identif... by Marlene Makenzius, Miranda Håkansson, Sanny Söderström

“…SEXIT aided SHPs in acting as educators to promote SRH and freedom from violence, normalised conversations about sensitive topics, facilitated the identification of students needing support, and could be integrated as a routine part of preventive work within SHS. However, hindering factors for effective implementation included a lack of supportive leadership and a unified approach among involved organisations to clarify roles, responsibilities and referral pathways. …”
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Optimal Monitoring Time Interval for Radio-Electronic Equipment Unsteady Failure Rate by S. S. Sokolov

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