The precise implementation of the ecological water transfer project effectively promotes the enhancement of desert riparian ecosystem service value in the mainstream of Tarim River by Ziwei Kang, Hongbo Ling, Yanming Gong, Junjie Yan, Feifei Han, Qianjuan Shan, Guangpeng Zhang

Get full text

Plasma and complement proteins are essential for the antimicrobial activity of canine platelet lysate by Melikasadat Mollabashi, Melikasadat Mollabashi, Alonza Klopfer, Alonza Klopfer, Thainá Lunardon, Thainá Lunardon, Nikolia Darzenta, Nikolia Darzenta, Emily Davis, Matt Murray, Scarlett M. Sumner, Maria C. Naskou, Maria C. Naskou

“…Specifically, platelets play a crucial role during the inflammatory phase of wound healing due to the release of chemokines, proteins, cytokines, and growth factors. Additionally, platelets possess antimicrobial properties, which can be influenced by their manufacturing process, platelet and leukocyte concentration, activation method, and the presence of plasma and complement. …”
Get full text

Complement system is activated in acute inflammatory response to environmental particulates in the lungs by Kerui Zhang, Akiko Honda, Tomoya Sagawa, Natsuko Miyasaka, Binyang Qiu, Raga Ishikawa, Tomoaki Okuda, Takayuki Kameda, Kaori Sadakane, Takamichi Ichinose, Hirohisa Takano

“…Short-term exposure (typically ranging from a few hours to 7 days) to particulate matter (PM) elicits acute inflammatory responses with significant activation of complement component C5. However, the relationship between PM-induced complement system activation, acute inflammation, and the contributing factors remains unclear. …”
Get full text

Kidney Disease: Improving Global Outcomes Summit Recommendations on Implementation of Diabetes Management in CKD: From Primary to Data-Driven Collaborative Care by Philip Kam-Tao Li, Michael Cheung, Kai-Ming Chow, Maria Kwan Wa Leung, Lee-Ling Lim, Juliana N.M. Lui, Andrea O.Y. Luk, Jo-Anne Manski-Nankervis, Samuel Seidu, Nikhil Tandon, Adrian Liew, Peter Lin, Fei Chau Pang, Na Tian, Kohjiro Ueki, Martin C.S. Wong, Sophia Zoungas, Kit Man Loo, Kin Lai Chung, Victor Hin-Fai Hung, Huyen Thi Thanh Vu, Maggie Lee, Junne-Ming Sung, Cheuk Chun Szeto, Man Wo Tsang, Sunny Wong, Jack Kit Chung Ng, Harriet Chung, Sydney C.W. Tang, Kenny Kung, Sing Leung Lui, David V.K. Chao, Coral Cyzewski, Tanya Green, Juliana C.N. Chan

“…In this report, we highlight the barriers and gaps in the implementation of practice guidelines in managing diabetes in CKD with proposed solutions to overcome such barriers. …”
Get full text

Population-based Cardiovascular Disease Prevention Measures Aimed at Reducing Salt Intake: Analysis of International Strategies and Prospects for Implementation in the Russian Fede... by Yu. A. Balanova, A. V. Kontsevaya, N. S. Karamnova, D. K. Mukaneeva, O. M. Drapkina

“…High salt intake is an important risk factor for cardiovascular diseases (CVD), closely related to the level of blood pressure in the population. …”
Get full text

Barriers and Facilitators to Delivering Multifactorial Risk Assessment and Communication for Personalized Breast Cancer Screening: A Qualitative Study Exploring Implementation in C... by Meghan J. Walker, Anna Neely, Antonis C. Antoniou, Mireille J. M. Broeders, Jennifer D. Brooks, Tim Carver, Jocelyne Chiquette, Douglas F. Easton, Andrea Eisen, Laurence Eloy, D. Gareth R. Evans, Samantha Fienberg, Yann Joly, Raymond H. Kim, Bartha M. Knoppers, Aisha K. Lofters, Hermann Nabi, Nora Pashayan, Tracy L. Stockley, Michel Dorval, Jacques Simard, Anna M. Chiarelli

“…One focus group and three one-on-one interviews were conducted and a thematic analysis conducted which identified five themes: (1) barriers and facilitators to recruitment for multifactorial risk assessment, (2) barriers and facilitators to completion of the risk factor questionnaire, (3) additional resources required to implement multifactorial risk assessment, (4) the need for a person-centered approach, and (5) and risk literacy. …”
Get full text

The quantum circuit implementation and feasibility analysis of quantum public-key cryptosystem based on the $$QSCD_{ff}$$ Q S C D ff problem by Anyi Li, Qiqing Xia, Qianru Zhu, Li Yang

“…Our specific focus lies in the quantum circuit implementations and fault-tolerant construction, which serve as essential prerequisites for the physical feasibility of quantum cryptographic schemes. …”
Get full text

Adapting self-measured blood pressure monitoring to reduce health disparities (ASPIRE): a pilot hybrid effectiveness‑implementation study protocol by Rasha Khatib, Nicole Glowacki, Iridian Guzman, Maureen Shields, Joseph Chase, Melanie Gordon

“…Qualitative interviews with patients and providers will explore the appropriateness and implementation success of the toolkit using the Consolidated Framework for Implementation Research (CFIR). …”
Get full text

Endothelial damage and complement dysregulation in fetuses from pregnancies complicated by preeclampsia by Alex Ramos, Lina Youssef, Patricia Molina, Julia Martinez‐Sanchez, Ana Belen Moreno‐Castaño, Miquel Blasco, Blanca De Moner, Marta Tortajada, Marta Camacho, Maria Borrell, Francesca Crovetto, Marc Pino, Gines Escolar, Enric Carreras, Eduard Gratacos, Maribel Diaz‐Ricart, Marta Palomo, Fatima Crispi

“…In the ex vivo approach, soluble tumor necrosis factor‐a receptor 1 (sTNFR1), vascular cell adhesion molecule‐1 (sVCAM‐1), intercellular adhesion molecule‐1 (sICAM‐1), Von Willebrand factor (sVWF), terminal complement complex (sC5b‐9), Factor H, complement component C3a and Factor Bb were analyzed in fetal cord blood samples. …”
Get full text

Simultaneous activation of complement and coagulation by MBL-associated serine protease 2. by Anders Krarup, Russell Wallis, Julia S Presanis, Péter Gál, Robert B Sim

“…The complement system is an important immune mechanism mediating both recognition and elimination of foreign bodies. …”
Get full text

Zinc supplementation inhibits complement activation in age-related macular degeneration. by Dzenita Smailhodzic, Freekje van Asten, Anna M Blom, Frida C Mohlin, Anneke I den Hollander, Johannes P H van de Ven, Ramon A C van Huet, Joannes M M Groenewoud, Yuan Tian, Tos T J M Berendschot, Yara T E Lechanteur, Sascha Fauser, Chris de Bruijn, Mohamed R Daha, Gert Jan van der Wilt, Carel B Hoyng, B Jeroen Klevering

“…We investigated whether zinc supplementation directly affects the degree of complement activation in AMD and whether there is a relation between serum complement catabolism during zinc administration and the complement factor H (CFH) gene or the Age-Related Maculopathy susceptibility 2 (ARMS2) genotype. …”
Get full text

Successful treatment of anti-factor H antibody-associated atypical hemolytic uremic syndrome with plasm exchange plus rituximab and tacrolimus: one case report by Pu Jin-yun, Chen Ya-xian, He Yong-hua, Zhang Yu

Subjects: Get full text

Kidney transplantation using complement inhibitor in a patient suffering from atypical hemolytic-uremic syndrome associated with factor H antibodies: successful prevention of recurrence of the underlying disease by E. I. Prokopenko, S. A. Pasov, A. V. Vatazin, A. Ya. Tsalman, T. E. Pankratenko, G. A. Generalova

“…We describe the clinical observation of a 20-year-old female patient with aHUS associated with antibodies to factor H, a major regulator of complement activation. …”
Get full text

Implementing a digital treatment program for patients with irritable bowel syndrome into routine care: a qualitative evaluation of barriers and facilitators perceived by key stakeh... by Camilla Thuen, Hanne Karoline Hinderaker, Elisabeth Kjelsvik Steinsvik, Linn Anja Slåke Vikøren, Gülen Arslan Lied, Birgitte Berentsen, Robin Maria Francisca Kenter

“…Our findings demonstrate that leveraging factors that aid implementation is important, while addressing barriers is crucial to ensure sustainable implementation. …”
Get full text

Evaluating challenges of implementing Industry 5.0 in the renewable energy supply chain toward sustainability: A comparative analysis using decision-making approaches by Seyyed Jalaladdin Hosseini Dehshiri, Maghsoud Amiri

“…The main challenges are insufficient investment and attention to information security for implementing I5.0 in the RE supply chain. Measures and financial incentives for the development of internal and external cooperation and data security measures, advanced encryption protocols, and basic security and cyber actions are necessary to attract investment and create a safe environment.…”
Get full text

Association between circulatory complement activation and hypertensive renal damage: a case–control study by Zhongli Wang, Tingting Zhang, Xinyu Wang, Jianlong Zhai, Lili He, Sai Ma, Qingjuan Zuo, Guorui Zhang, Yifang Guo

“…Objective The aim of this study was to investigate the potential importance of complement system activation, with particular emphasis on the complement alternative pathway (AP), in the pathogenesis of hypertensive renal damage.Methods Serum complement C3, complement Factor H (CFH) and AP activation were assessed in 66 participants with established essential hypertension with renal damage (RD). …”
Get full text

Health economic evaluation of implementing a universal immunization program with nirsevimab compared to standard of care for the prevention of respiratory syncytial virus disease i... by Thomas Shin, Jason Kh Lee, Alexia Kieffer, Michael Greenberg, Jianhong Wu

Get full text

Cultural and ethical barriers to implementing end-of-life advance care planning among oncology nursing professionals: a content analysis of open-ended questions by Yi-An Shih, Cheng Wang, Jiahui Ding, Yuhong Zhou, Qian Lu

“…Three main interdependent barriers emerged: (1) Cultural norms, including filial piety (15.6% of codes) and death-related taboos (11.0%), often led to family-mediated decision-making (33.1%) over patient autonomy; (2) Ethical dilemmas involved neglecting patient preferences (24.3%) and conflicts between life-prolonging treatments and quality-of-life considerations (8.1%); (3) Communication challenges arose from information asymmetry (7.9%) and power imbalances, which often silenced patient voices. These factors collectively created systemic obstacles to ACP implementation. …”
Get full text

Complement component C1q initiates extrinsic coagulation via the receptor for the globular head of C1q in adventitial fibroblasts and vascular smooth muscle cells by Christopher T. Freda, Wei Yin, Berhane Ghebrehiwet, David A. Rubenstein

Subjects: “…complement…”
Get full text

Scaling up of parenting support to prevent violence against children in Tanzania: insights from policymakers and service providers by Sabine van Tuyll van Serooskereken Rakotomalala, Kija Nyalali, Joyce Wamoyi, Onduru Gervas Onduru, Gerry Mshana, F. Marijn Stok, Mara A. Yerkes, John B. F. De Wit

“…Current factors hindering the scale-up include the lack of a common understanding of what evidence-based parenting programmes entail, inadequate provision of human and financial capital to implement the programmes using community resources and deeply engrained social norms around adultism and gender. …”
Get full text