Implementation Method and Bench Testing of Fractional-Order Biquadratic Transfer Function-Based Mechatronic ISD Suspension by Yujie Shen, Dongdong Qiu, Haolun Xu, Yanling Liu, Kecheng Sun, Xiaofeng Yang, Yan Guo

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Enhancing Handover Quality and Continuity of Care: Implementation and Evaluation of a Digital Handover System in Grangewood Hospital, Northern Ireland by Lewis Kitchen, Adam Flynn

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Building the "Smart Village" Through the implementation of the Non-Formal Education to Improve English Language Skills In the village of Geluran Taman Sidoarjo" by Ani Faujiah

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Angiotensinogen and C3 compete for renin-induced complement activation by Ann-Charlotte Kristoffersson, Albin Sköld, Charlotte Welinder, Markus Wendler, Gabriella Kalliokoski, Zivile Bekassy, Diana Karpman

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Association of Proliferative Diabetic Retinopathy in the Elderly with the Blood Complement System by O. L. Fabrikantov, N. M. Agarkov, I. V. Lev, T. S. Gurko, S. I. Nikolashin

“…The highest value of the relative risk among the studied components is inherent in the C3a component of the blood complement with a reliable confidence interval of 4,451–5,103. …”
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Barriers and Facilitators Experienced During the Implementation of Web-Based Teleradiology System in Public Hospitals of the Northwest Ethiopia: An Interpretive Description Study by Araya Mesfin Nigatu, Tesfahun Melese Yilma, Lemma Derseh Gezie, Yonathan Gebrewold, Monika Knudsen Gullslett, Shegaw Anagaw Mengiste, Binyam Tilahun

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Synthesis and propagation of complement C3 by microglia/monocytes in the aging retina. by Matt Rutar, Krisztina Valter, Riccardo Natoli, Jan M Provis

“…We aimed to investigate the expression and localization of C3, a crucial component of the complement system, in the retina during the course of aging.…”
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Endothelial damage and complement dysregulation in fetuses from pregnancies complicated by preeclampsia by Alex Ramos, Lina Youssef, Patricia Molina, Julia Martinez‐Sanchez, Ana Belen Moreno‐Castaño, Miquel Blasco, Blanca De Moner, Marta Tortajada, Marta Camacho, Maria Borrell, Francesca Crovetto, Marc Pino, Gines Escolar, Enric Carreras, Eduard Gratacos, Maribel Diaz‐Ricart, Marta Palomo, Fatima Crispi

“…In the ex vivo approach, soluble tumor necrosis factor‐a receptor 1 (sTNFR1), vascular cell adhesion molecule‐1 (sVCAM‐1), intercellular adhesion molecule‐1 (sICAM‐1), Von Willebrand factor (sVWF), terminal complement complex (sC5b‐9), Factor H, complement component C3a and Factor Bb were analyzed in fetal cord blood samples. …”
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Evaluation of an Electronic Application for Enhancing Medication Adherence Among Hypertensive Patients: A Qualitative Research Based on Consolidated Framework for Implementation Re... by Sichen Wang, Junjie Huang, Apurva Sawhney, Xianjing Liu, Chaoying Zhong, Jianli Lin, Junjie Hang, Claire Chenwen Zhong, Jinqiu Yuan, Martin C. S. Wong

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Complement activation by the artificial surface of cardiopulmonary bypass is a persistent clinical problem by Joel David Bierer, Roger Stanzel, Mark Henderson, Tony El-Rabahi, John Sapp, Pantelis Andreou, Jean S. Marshall, David Conrad, David Horne

“…Sequential samples were collected during forty-five ex-vivo sanguineous prime preparations of CPB circuits coated with phosphorylcholine, as a biocompatibility technology, to characterize complement activation in this context. We observed and quantified evidence of alternative and terminal complement pathway activation indicated by dynamic concentration increases of C3a, C3b, C5a and terminal complement complex. …”
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Modified Methylation Following Electrostimulation in a Standardized Setting—Complementing a Transcriptomic Analysis by Biagio Di Pietro, Simona Villata, Anna Plaksienko, Tiziana Guarnieri, Simeone Dal Monego, Margherita Degasperi, Pietro Di Lena, Danilo Licastro, Claudia Angelini, Francesca Frascella, Lucia Napione, Christine Nardini

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Complement 3a Mediates CCN2/CTGF in Human Retinal Pigment Epithelial Cells by Kang Xiao, Zhiyan Xu, Zhengyu Chen, Qin Long, Youxin Chen

“…Background. Complement 3 (C3) is the crucial component of the complement cascade when retina was exposed to external stimulus. …”
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Clinical significance of circulating immune complexes and components of the blood complement system in viral meningitis in children by G. A. Kharchenko, O. G. Kimirilova

“…As the main target laboratory parameters, the concentration of complement components: C1inh, C4, C3a in blood plasma was determined by ELISA using the kits of reagents «ELISA-Clinh», «ELISA-C4», «ELISA-C3a». …”
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Multi-functional mechanisms of immune evasion by the streptococcal complement inhibitor C5a peptidase. by Nicola N Lynskey, Mark Reglinski, Damien Calay, Matthew K Siggins, Justin C Mason, Marina Botto, Shiranee Sriskandan

“…The complement cascade is crucial for clearance and control of invading pathogens, and as such is a key target for pathogen mediated host modulation. …”
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Functional mass spectrometry indicates anti-protease and complement activity increase with COVID-19 severity by Douglas D. Fraser, Douglas D. Fraser, Swapan Roy, Matt Kuruc, Maritza Quintero, Logan R. Van Nynatten, Gediminas Cepinskas, Gediminas Cepinskas, Haiyan Zheng, Amenah Soherwardy, Devjit Roy

“…Evaluation of the AAT/ACT ratio and C3a/C3beta ratio indicated that COVID-19 severity is associated with both neutrophil elastase neutralization and complement activation.…”
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Acute induction of interleukin-6 and biphasic changes of serum complement C3 by carrageenan in mice by K. Tateda, T. Matsumoto, K. Yamaguchi

“…Prior to the rise in complement C3, a sharp peak of serum IL-6 was observed at 6 h after carrageenan treatment. …”
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Africanized honeybee venom (Apis mellifera) promotes human complement activation split products storm by Felipe Silva de França, Felipe Silva de França, Ricardo de Oliveira Orsi, Dayanne Carla Fernandes, Dayanne Carla Fernandes, Thyago Bispo Leonel, Thyago Bispo Leonel, Denise V. Tambourgi, Denise V. Tambourgi

“…Strikingly, NHS exposed to increasing AmV concentrations varying from 5 to 1000 µg/mL presented a high generation of C3a, C4a and C5a anaphylatoxins, and sC5b-9 complexes assembly, thus reinforcing that AmV triggers complement activation.ConclusionThese results show that AmV is a strong complement activator. …”
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The specific contributions of factor H and factor I in controlling fluid phase activation of the alternative complement pathway by Nancy A. Turner, Joel L. Moake

“…Abstract The immediate defense provided by the alternative complement pathway (AP) is under constant control by fluid phase regulators, factor H (FH) and factor I (FI), to prevent nonessential activation. …”
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Increased Autoreactivity of the Complement-Activating Molecule Mannan-Binding Lectin in a Type 1 Diabetes Model by Jakob Appel Østergaard, Marieta Milkova Ruseva, Talat Habib Malik, Ingeborg Torp Hoffmann-Petersen, Matthew Caleb Pickering, Steffen Thiel, Troels Krarup Hansen

“…Diabetes and control groups did not differ in glomerular immunofluorescence intensity obtained by antibodies against complement factors C4, C3, and C9. However, the circulating complement activation product C3a was increased in diabetes as compared to control mice (P=0.04). …”
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Genotypic and phenotypic diversity of Lactobacillus rhamnosus clinical isolates, their comparison with strain GG and their recognition by complement system. by Eija Nissilä, François P Douillard, Jarmo Ritari, Lars Paulin, Hanna M Järvinen, Pia Rasinkangas, Karita Haapasalo, Seppo Meri, Hanna Jarva, Willem M de Vos

“…The capacity of the L. rhamnosus strains to activate serum complement was studied using immunological assays for complement factor C3a and the terminal pathway complement complex (TCC). …”
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