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Exploring the Chemical and Pharmaceutical Potential of Kapakahines A–G Using Conceptual Density Functional Theory-Based Computational Peptidology
Published 2025-05-01“…Alongside the calculation of global and local reactivity descriptors, predicted ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) profiles and pharmacokinetic parameters, including pKa and LogP, are evaluated. The integrated computational analysis provides insights into the stability, reactivity, and potential drug-like behavior of these marine-derived cyclopeptides and contributes to the theoretical groundwork for future studies aimed at optimizing their bioactivity and safety profiles.…”
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How adolescents learn to build social bonds: A developmental computational account of social explore-exploit decision-making
Published 2024-10-01“…Our account provides important new directions for examining the dynamics of adolescent behavior in social groups and understanding how social value computations can support positive relationships into adulthood.…”
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Design and application of human-computer interaction visual communication platform for Guandong culture by integrating RF and light GBM algorithm
Published 2025-02-01“…Light gradient boosting machine performed excellently and had high computational efficiency when processing large-scale data through an efficient gradient boosting framework. …”
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Prediction of single nucleotide polymorphisms of RNA dependent RNA polymerase for the potato leafroll virus using computational and experimental approaches
Published 2025-08-01“…These tools enabled us to assess the potential level and location of disorder within proteins, providing crucial insights into their behavior. In our study, the polymerase chain reaction (PCR) yielded a product corresponding to the PLRV-RdRp gene, measuring 450 base pairs (bp). …”
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Reduced order data driven framework for computation of the unsteady lid-driven cavity flow using dynamic mode decomposition
Published 2025-05-01“…They were used to achieve reduced-order models for predicting dynamic behavior of the flow field. Validation of CFD computation was assessed, and independence of the DMD modes from the data collection process was investigated. …”
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Computational Models of Dynamic Load Sources for Modeling of Construction Structures Operation Used in Monitoring of Technical Condition of Buildings and Structures
Published 2024-10-01“…The article presents research materials on computational equivalent models of dynamic load sources for numerical modeling of the behavior of construction structures under their influence, using the method of vibroacoustic analogies. …”
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Comprehensive Computational Assessment of SNAI1 and SNAI2 in Gastric Cancer: Linking EMT, Tumor Microenvironment, and Survival Outcomes
Published 2025-06-01“…Conclusion: This study highlights the significant prognostic impact of SNAI1 and SNAI2 in stomach adenocarcinoma, linking their high expression to poorer survival and aggressive tumor behavior, while also identifying potential therapeutic targets through comprehensive computational analysis.…”
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Computational identification of novel natural inhibitors against triple mutant DNA gyrase A in fluoroquinolone-resistant Salmonella Typhimurium
Published 2025-03-01“…The rising resistance to fluoroquinolones in Salmonella Typhimurium poses a significant global health challenge. This computational research addresses the pressing need for new therapeutic drugs by utilizing various computational tools to identify potential natural compounds that can inhibit the triple mutant DNA gyrase subunit A enzyme, which is crucial in fluoroquinolone resistance. …”
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Computational Model and Constructal Design Applied to Thin Stiffened Plates Subjected to Elastoplastic Buckling Due to Combined Loading Conditions
Published 2025-03-01“…Several researchers have investigated the influence of stiffeners on plates under different loading conditions. However, the behavior under combined biaxial compression and lateral pressure has not yet been widely explored. …”
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Experimental acoustic study of small horizontal axis wind turbines based on computational fluid dynamics and artificial intelligence approaches
Published 2024-12-01“…Utilizing Class-Shape Transformation to parameterize various serrated airfoil geometries, the method minimizes the need for costly computational fluid dynamics (CFD) simulations. Instead, a feed-forward neural network (NN) is trained with a minimal dataset to predict airfoil behavior within a specified range. …”
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Intradural-Extramedullary Solitary Fibrous Tumor/Hemangiopericytoma with a Negative Result on Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography
Published 2019-01-01“…Whole-body fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) was also performed, showing no accumulation. …”
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ASPECTS REGARDING THE EFFECTS OF THE COVID-19 PANDEMIC ON THE 10 – 11-YEAR-OLD CHILDREN'S ACTIVE MOTOR, DIETARY, AND PSYCHOLOGICAL BEHAVIOR
Published 2023-06-01“…The children had to study online classes a large portion of their time, which has contributed to a significant increase in the hours they have spent in front of a computer. The objective of this study was to emphasize the effects of the Coronavirus pandemic on the relation between the active motor behavior, the dietary behavior, and the psychological behavior in 10-11-year-old children of Bacau, Romania. …”
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ABDviaMSIFAT: Abnormal Crowd Behavior Detection Utilizing a Multi-Source Information Fusion Technique
Published 2025-01-01“…Detecting abnormal crowd behavior in surveillance videos is a significant challenge due to the intricate and constantly evolving crowd dynamics. …”
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ON THE QUESTION OF THE EVACUATION OF CHILDREN FROM CHILDREN'S PLAYROOMS OF SHOPPING MALLS
Published 2022-10-01Subjects: Get full text
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Memory Manufacture Under Microgravity (MMuM): In‐Space Manufactured ZnO‐Based Resistive Random Access Memory for Emerging Computing Application
Published 2025-08-01“…Abstract Resistive random access memory (RRAM) has attracted industrial and academic interests in emulating biological synapse features for neuromorphic computing for its flexibility and feasibility of analog behaviors. …”
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