Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tissues by Minseo Kim, Dianjun Cao, Vincent Cavaleri, Kyudong Han, Kyudong Han, Kyudong Han, Seyoung Mun, Seyoung Mun, Seyoung Mun, Soo Jin Jeon

“…Together, these transcriptional changes suggest that ESD may compromise physiological functions such as immune defense, energy metabolism, and stress response, while promoting chitin degradation and cuticle remodeling in response to shell infection. …”
Get full text

Vocal brain development in infants of mothers with serious mental illness (CAPRI-Voc): study protocol by Kathryn M Abel, Chen Zhao, Rebecca Elliott, Matthias Pierce, Holly Hope, Lucy Stibbs-Eaton, Catherine Hodgson, Adekeye Kolade, Jennifer Crowell, Jessica Gemignani, Alya Elmadih, Darragh Downey

“…Both cohorts of infants will undergo functional near infrared spectroscopy (fNIRS) brain imaging at three time points: 9, 12 and 18 months to explore differences between cohorts in their neural responses to vocal stimuli in our language paradigm. …”
Get full text

Glucocorticoid Receptor (GR) Expression in Human Tumors: A Tissue Microarray Study on More than 14,000 Tumors by Maria Christina Tsourlakis, Simon Kind, Sebastian Dwertmann Rico, Sören Weidemann, Katharina Möller, Ria Schlichter, Martina Kluth, Claudia Hube-Magg, Christian Bernreuther, Guido Sauter, Andreas H. Marx, Ronald Simon, Ahmed Abdulwahab Bawahab, Florian Lutz, Viktor Reiswich, Davin Dum, Stefan Steurer, Eike Burandt, Till S. Clauditz, Till Krech, Christoph Fraune, Seyma Büyücek, Neele Heckmann, Natalia Gorbokon, Maximilian Lennartz, Sarah Minner, Florian Viehweger

“…Associations between reduced GR expression and unfavorable tumor features in certain cancers suggest that the functional importance of GR-regulated genes in cancer progression depends on the cell of tumor origin.…”
Get full text

2-Hydroxyisobutyric acid targeted binding to MT-ND3 boosts mitochondrial respiratory chain homeostasis in hippocampus to rescue diabetic cognitive impairment by Minzhen Xie, Siqi Gu, Yan Liu, Haolin Yang, Yuqi Wang, Wei Yin, Yang Hong, Wanying Lu, Chengbing He, Lin Li, Limin Zhao, Jianjia Zhang, Heng Liu, Tian Lan, Shuijie Li, Qi Wang

“…Conclusion: MT-ND3 is a crucial target for improving diabetic cognitive dysfunction, and 2-HIBA can directly bind to the MT-ND3 protein to alleviate the functional impairment of the mitochondrial respiratory chain in mice to treat DCI.…”
Get full text

Impact of extraction methods on the properties of Carica papaya pseudostem fibers from Cameroon used as reinforcement in biocomposites by Jean Aimé Mono, Sandrine Emvoutou Ndongo, Odette Thérèse Adegono Assiene, Armel Mewoli, Rachelle Appolince Nguefack Assona, Richard Hervé Bitete, Giresse Ulrich Defo Tatchum, Claude Takoumbe

“…Fourier transform infrared spectroscopy (FTIR) of Carica papaya fibers extracted by water retting and those extracted with NaOH indicates that the cellulose, hemicellulose, and lignin functional groups are present in the fibers and are dissolved considerably as the percentage of NaOH increases. …”
Get full text

Dissolved copper enrichment in the Gulf of Mexico is driven by freshwater inputs, sedimentary fluxes, and cross-shelf exchange induced by Loop Current eddies by Francisco Delgadillo-Hinojosa, Armando Félix-Bermúdez, Eunise Vanessa Torres-Delgado, Miguel Angel Huerta-Diaz, Maria Lucila Lares, Antonio Tovar-Sánchez, Sandra Laura Quijano-del-Olmo, Mauricio Moises Reyes-Bravo

“…In the ocean, copper functions as an essential micronutrient for primary producers but becomes toxic if its concentration exceeds their cellular requirements. …”
Get full text

CPLX1 is a novel prognostic biomarker in CRC correlating with immunotherapy resistance and ferroptosis by Canyu Liu, Qiujun Liu, Yuanhao Lv, Tingmin Chang, Shiyi Song, Yuang Ding, Jiateng Zhong, Jiateng Zhong, Jiateng Zhong, Jiateng Zhong, Jiateng Zhong, Yanxuan Liu

“…Additionally, mutational analyses through cBioPortal and COSMIC datasets were employed to identify CPLX1 mutations in COAD. Co-expression and functional enrichment analyses, alongside Gene Set Enrichment Analysis (GSEA), were also conducted to delineate pathways impacted by CPLX1.ResultsOur findings indicate that high expression levels of CPLX1 are significantly correlated with poor prognostic outcomes in CRC patients. …”
Get full text

A novel optimized silver nitrate staining method for visualizing the osteocyte lacuno-canalicular system by Jinlian Wu, Jinlian Wu, Chunchun Xue, Qiang Li, Hongjin Wu, Jie Zhang, Chenglong Wang, Weiwei Dai, Libo Wang

“…The technique consistently produced clear, distinct staining patterns across all samples. …”
Get full text

DREB Genes from Common Bean (Phaseolus vulgaris L.) Show Broad to Specific Abiotic Stress Responses and Distinct Levels of Nucleotide Diversity by Enéas Ricardo Konzen, Gustavo Henrique Recchia, Fernanda Cassieri, Danielle Gregorio Gomes Caldas, Jorge C. Berny Mier y Teran, Paul Gepts, Siu Mui Tsai

“…PvDREB6B was previously described as an A-2 (DREB2) gene, but a detailed phylogenetic analysis and its expression profile clearly indicated it belongs to group A-6. PvDREB6B was found as a cold- and dehydration-responsive gene, mainly in leaves. …”
Get full text

Contemporary techniques and outcomes of surgery for locally advanced renal cell carcinoma with focus on inferior vena cava thrombectomy: The value of a multidisciplinary team by Riccardo Campi, Paolo Barzaghi, Alessio Pecoraro, Maria Lucia Gallo, Damiano Stracci, Alberto Mariotti, Saverio Giancane, Simone Agostini, Vincenzo Li Marzi, Arcangelo Sebastianelli, Pietro Spatafora, Mauro Gacci, Graziano Vignolini, Francesco Sessa, Paolo Muiesan, Sergio Serni

“…Our experience confirms that provided careful patient selection, surgery in experienced hands can achieve favourable perioperative, oncological, and functional outcomes.…”
Get full text

Grazing-induced abiotic and resource changes drive distinct responses of soil bacterial and fungal community in temperate meadow steppe: Implications for carbon dynamics by Cuixia Jiang, Xiaoping Xin, Kai Xue, Zhigang Zhao, Weixing Liu, Haonan Guo, Feng Liu, Hui Li, Zihao Li, Yufan Si, Ruirui Yan

“…Soil microbial communities play a crucial role in maintaining grassland ecosystem functions and are strongly influenced by livestock grazing. …”
Get full text

EST–SSR Marker Development and Full-Length Transcriptome Sequence Analysis of Tiger Lily (Lilium lancifolium Thunb) by Mingwei Sun, Yilian Zhao, Xiaobin Shao, Jintao Ge, Xueyan Tang, Pengbo Zhu, Jiangying Wang, Tongli Zhao

“…Around 15,608 transcripts were allocated to 25 distinct KOG Clusters, and 10,706 unigenes were grouped into 52 functional categories in the annotated transcripts. …”
Get full text

Post-Soviet single-industry cities in northern Russia: movement towards sustainable development by Diana Dushkova, Tatyana Krasovskaya

“…Most challenges are connected with structural and paradigm changes in economy and functionality of enterprises after the collapse of the Soviet Union. …”
Get full text

STUDY OF NOOTROPIC AND ANTI-HYPOXIC ACTIVITY OF 5-AMINO-3-EXO-AZATRICYCLO[5.2.1.0^2,6]DECAN-4-ON by T. A. Sapozhnikova, N. S. Makara, S. F. Gabdrakhmanova, R. Yu. Khisamutdinova

“…One of the classes of ND are pyrrolidone derivatives, which, in addition to a direct effect on cognitive functions, increase the brain's resistance to hypoxia.Aim. …”
Get full text

Professor Tadeusz Poklewski-Koziełł and the Research on the Development of the Agriculture Technology in Medieval and Modern Poland by Jerzy Maik

“…Also on the route of another future highway, in Pomorzany near Kutno, the expedition of the Łódź Center examined the remains of a grange, which functioned there from the 14th c., geared towards animal husbandry. …”
Get full text

Predictive Influence of Socio-Demographic Characteristics on Adaptive Achievements Of Children With Developmental Disorders by Slađana Ćalasan, Nadica Jovanović-Simić, Bojana Drljan

“…In conclusion, socio-demographic characteristics as predictive variables have varying impacts on adaptive functioning across different groups of children.…”
Get full text

Analysis of Continuous Auditing Implementation in The Public Sector: A Case Study of the Ministry of ABC by Sri Suharto, Heny Kurniawati

“…The Ministry of ABC plays a strategic role in governance, involving functions such as planning, fund allocation, monitoring, and controlling development planning. …”
Get full text

Bishop Jeremiah (Soloviev) as a compiler of akathists by Maria Sidneva

“…The akathist work of Bishop Jeremiah is a vivid example of the hymnography of the "Learned Monasticism", in which more and more often a place was given to akathist writing in the Modern Times. …”
Get full text

Integrating smart technologies in ecotourism opportunities development by R. M. Sahahiri

“…Tourism planners, environmentalists, and lawmakers might learn from the proposed paradigm on sustainable ecotourism and smart tourism in heritage-rich places.…”
Get full text

The Role of Latvian Catholic Church Textiles in Perfecting People’s Aesthetic Values by Aija Jansone

“…The decorated church’s textiles encouraged the peasants to learn new crafts, to make their clothing and interior designs more beautiful and timely. …”
Get full text