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    Machine Learning‐Driven Prediction, Preparation, and Evaluation of Functional Nanomedicines Via Drug–Drug Self‐Assembly by Chengyuan Zhang, Yuchuan Yuan, Qiong Xia, Junjie Wang, Kangkang Xu, Zhiwei Gong, Jie Lou, Gen Li, Lu Wang, Li Zhou, Zhirui Liu, Kui Luo, Xing Zhou

    Published 2025-03-01
    “…Nanomedicines, PEG‐coated indomethacin/paclitaxel nanomedicine (PiPTX), and laminarin‐modified indomethacin/paclitaxel nanomedicine (LiDOX), are developed with extended circulation and active targeting functions. Indomethacin/paclitaxel nanomedicine iDOX exhibits pH‐responsive drug release in the tumor microenvironment. …”
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    Deep Learning for Stomatal Opening Recognition in <i>Gynura formosana</i> Kitam Leaves by Xinlong Shi, Yanbo Song, Xiaojing Shi, Wenjuan Lu, Yijie Zhao, Zhimin Zhou, Junmai Chai, Zhenyu Liu

    Published 2024-11-01
    “…<i>Gynura formosana</i> Kitam possesses beneficial properties such as heat-clearing, detoxification, and cough suppression, making it a highly nutritious plant with significant economic value. …”
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    AURKB affects the proliferation of clear cell renal cell carcinoma by regulating fatty acid metabolism by Yang Yang, Dan Li, Zhigang Liu, Kai Zhou, Wenxing Li, Yanqi Yang, Ruifang Sun, Yulong Li

    Published 2025-01-01
    “…Methods We performed bioinformatics analysis, CCK-8 assay, RNA sequencing, RT-PCR and Western blot to analyze the function and mechanism of AURKB in ccRCC. Results TIMER2.0 showed that AURKB was overexpressed in Kidney Renal Clear Cell Carcinoma (KIRC), the UALCAN database showed the survival rate of KIRC patients with different expression levels of AURKB and different gender indicated in the same gender, high AURKB expression predicts lower survival rate. …”
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    Article
  10. 270

    Creative use of Clear Aligners with Tongue Spikes for Open Bite Correction: A Case Report by Ricardo Alexandre Laske, Rosilene Andrea Machado, Gil Guilherme Gasparello, Thiago Martrtins Meira, Orlando Motohiro Tanaka

    Published 2025-07-01
    “…The application of a mandibular clear aligner combined with a tongue spike successfully treated the AOB caused by the patient’s tongue rest posture, leading to improved aesthetics, function, and patient satisfaction. …”
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    Article
  11. 271

    Development of a Dual-Sided Soil-Clearing Machine with Scraping, Rotating, and Vibrating Components for Winemaking Grapes by Xiang Li, Fazhan Yang, Baogang Li, Yuhuan Li, Ruijun Sun, Zehui Peng

    Published 2024-12-01
    “…To address prominent issues in the spring soil removal process for wine grapes in northern China, such as incomplete soil clearing, vine damage, and low operational efficiency, a dual-sided soil removal machine combining scraping, rotary, and vibration functions was designed and developed. …”
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  12. 272

    Application of laser light backscattering for qualitative and quantitative assessment of dilution of clear and cloudy apple juices by Hoa Xuan Mac, Nga Thi Thanh Ha, László Friedrich, Lien Le Phuong Nguyen, László Baranyai

    Published 2025-03-01
    “…Multispectral data was extracted by signal approximation with Cauchy distribution function (M1) and first-order descriptive parameters (M2). …”
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  13. 273

    Nanotherapeutic Approaches of Interleukin‐3 to Clear the α‐Synuclein Pathology in Mouse Models of Parkinson's Disease by Wenlong Zhang, Jian Ren, Liuyan Ding, Shaohui Zheng, Runfang Ma, Mengran Zhang, Yan Liu, Ruijing Liang, Yunlong Zhang

    Published 2024-11-01
    “…Abstract Astrocyte‐microglia crosstalk is vital for neuronal survival and clearing aggregate accumulation in neurodegenerative diseases. …”
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  14. 274

    Kinesin-related genes stratified the prognosis and immune responses of clear cell renal cell carcinoma by Wenchong Zang, Luqi Ge, Xiaoping Hu, Tong Xu, Zhentao Zhang, Yiwen Zhang, Feifeng Song

    Published 2025-07-01
    “…Abstract Background Clear cell renal cell carcinoma (ccRCC) is a prevalent and aggressive form of kidney cancer. …”
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  15. 275

    Genetic and therapeutic heterogeneity shape the baseline and longitudinal immune ecosystem of ovarian clear cell carcinoma by Min Yu, Fei Xu, Xiaohua Wu, Jiajia Li, Xiaojun Chen, Lihua Chen, Jiaxin Chen, Mengdong Ni, Siyu Xia, Jiana Li, Chaohua Liu

    Published 2024-11-01
    “…Background Ovarian clear cell carcinoma (OCCC) is a rare and chemo-resistant subtype of ovarian cancer. …”
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    A Feedback Loop Between Fatty Acid Metabolism and Epigenetics in Clear Cell Renal Carcinoma by Zhou Ye, Qi‐Xin Hu, Ming‐Liang Wei, Ji‐Dong Chen, Jia Shi, Ning‐Rong Yang, Lu Jiang, Jian Chen, Zhi‐Yuan Chen, Wei‐Min Yu, Yu Xiao, Kai‐Yu Qian, Zilin Xu, Zhong Wang, Wen‐Lu Qi, Xin‐Yi Xiao, Yu‐Yu Duan, Yong Xiao, Lian‐Yun Li, Lin‐Gao Ju, Ming‐Kai Chen, Min Wu

    Published 2025-07-01
    “…Abstract Lipid storage and epigenetic dysregulation are key features for clear cell renal carcinoma (ccRCC). However, the interplay between fatty acid metabolism and epigenetics in ccRCC remains to be further demonstrated. …”
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    Survey of research on application of heuristic algorithm in machine learning by Yanping SHEN, Kangfeng ZHENG, Chunhua WU, Yixian YANG

    Published 2019-12-01
    Subjects: “…parameter and structure optimization;feature optimization;ensemble pruning;prototype optimization;weighted voting ensemble;kernel function learning…”
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    Deep Learning-Based Algorithm for Road Defect Detection by Shaoxiang Li, Dexiang Zhang

    Published 2025-02-01
    “…With the increasing demand for road defect detection, existing deep learning methods have made significant progress in terms of accuracy and speed. …”
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