Cost-effectiveness of combining AI and cfDNA with LDCT for lung cancer screening in China: a modelling study by Mingjun Rui, Yingcheng Wang, Zhengwei Huang, Yunfei Li, Hongchao Li

“…Background: Lung cancer remains one of the leading causes of cancer-related mortality in China, where early detection through screening is critical for improving survival rates. Low-dose computed tomography (LDCT) has proven effective for early lung cancer screening, but its high false-positive rate increases the economic burden and psychological stress on patients. …”
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Knowledge, attitudes, and factors associated with the utilization of youth-friendly sexual and reproductive health services among teenagers and young adults in Kigali City, Rwanda by Julienne Nyirarukundo, Venuste Musugire, Boniface Nsengiyumva, Joella Mukashyaka, Zephanie Nzeyimana

“…In particular, youth centers may also offer vocational courses like welding, cooking, football, and computer literacy. However, there is limited information on the use of these services, especially in Kigali City. …”
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Comparative Evaluation of Apical Fit of Various Corresponding Gutta-percha Cones in Prepared S-shaped Canals of Simulated Mandibular Premolars: An In-vitro Study by Parul Bansal, Garima Singh, Mohit Kumar, Nikita Sharma, Smrity Sinha, Darshana Baruah

“…The apical fit of GP cones in all the models was assessed using Cone Beam Computed Tomography (CBCT). The obtained results were tabulated (One-way ANOVA and Post-hoc Tukey tests, p-value ≤0.0001, (highly significant) and subjected to statistical analysis using Statistical Package for Social Sciences (SPSS) Software. …”
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Development and Validation of an Interpretable Machine Learning Model for Prediction of the Risk of Clinically Ineffective Reperfusion in Patients Following Thrombectomy for Ischem... by Hu X, Qi D, Li S, Ye S, Chen Y, Cao W, Du M, Zheng T, Li P, Fang Y

“…The final model included ten parameters: EVT attempts, diabetes mellitus, previous ischemic stroke, National Institutes of Health Stroke Scale (NIHSS score), preoperative infarction in the basal ganglia, baseline diastolic blood pressure, clot burden score (CBS)/basilar artery on computed tomography angiography (BATMAN) score, stroke cause, collateral grade, and MLS.Conclusion: We developed and validated the first interpretable machine learning model for CIR prediction after EVT, surpassing traditional methods. …”
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MYOCARDITIS AS A LEGITIMATE PHENOMENON IN NON-COMPACTION MYOCARDIUM: DIAGNOSTICS, MANAGEMENT AND INFLUENCE ON OUTCOMES by O. V. Blagova, E. V. Pavlenko, N. V. Varionchik, A. V. Nedostup, V. P. Sedov, Е. A. Kogan, V. А. Zaydenov, А. G. Kupriyanova, A. Е. Donnikov, V. V. Kadochnikova, N. V. Gagarina, E. A. Mershina, V. Е. Sinitsyn, М. Е. Polyak, E. V. Zaklyazminskaya

“…Diagnosis of NCM had been done by echocardiography, multispiral computed tomography (n=81) and magnetic resonance tomography (n=39). …”
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Advancements and future prospects in the fundamental theories of rock blasting research Ⅳ — Damage evaluation by Renshu YANG, Chenglong XIAO, Jinjing ZUO, Guoying LI, Hao WANG, Peng XU, Chenxi DING, Yongliang LI, Yanbing WANG, Yong ZHAO, Shuai YOU, Zhen LIU, Yuantong ZHANG

“…Points refer to CT (Computed Tomography) scanning conducted on a rock core, lines pertain to borehole imaging inside the surrounding rock, surfaces relate to the blasting contour quality, and cubes involve cross-hole acoustic wave testing within the surrounding rock. …”
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Progression of the first stage of spontaneous labour: A prospective cohort study in two sub-Saharan African countries. by Olufemi T Oladapo, Joao Paulo Souza, Bukola Fawole, Kidza Mugerwa, Gleici Perdoná, Domingos Alves, Hayala Souza, Rodrigo Reis, Livia Oliveira-Ciabati, Alexandre Maiorano, Adesina Akintan, Francis E Alu, Lawal Oyeneyin, Amos Adebayo, Josaphat Byamugisha, Miriam Nakalembe, Hadiza A Idris, Ola Okike, Fernando Althabe, Vanora Hundley, France Donnay, Robert Pattinson, Harshadkumar C Sanghvi, Jen E Jardine, Özge Tunçalp, Joshua P Vogel, Mary Ellen Stanton, Meghan Bohren, Jun Zhang, Tina Lavender, Jerker Liljestrand, Petra Ten Hoope-Bender, Matthews Mathai, Rajiv Bahl, A Metin Gülmezoglu

“…Methodological advancements in statistical and computational techniques addressing the limitations of pioneer studies have led to novel findings and triggered a re-evaluation of current labour practices. …”
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Factors associated with utilization of skilled birth attendance among women of reproductive age in North Horr Sub-County, Northern Kenya, 2021 by Qabale Anna Duba, Elvis Omondi Oyugi, Paul Nyongesa, Joseph Obiero Ogutu

“…We interviewed the women using structured questionnaires and performed descriptive statistics. We computed the crude odds ratios (COR) at the bivariate analysis and the adjusted odds ratios (aOR) at the multivariable analysis together with their corresponding 95% confidence intervals (CI), and p-values to identify the factors associated with utilizing skilled birth attendance. …”
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Posterior hippocampal sparing in Lewy body disorders with Alzheimer’s copathology: An in vivo MRI study by Jesse S. Cohen, Jeffrey Phillips, Sandhitsu R. Das, Christopher A. Olm, Hamsanandini Radhakrishnan, Emma Rhodes, Katheryn A.Q. Cousins, Sharon X. Xie, Ilya M. Nasrallah, Paul A. Yushkevich, David A. Wolk, Edward B. Lee, Daniel Weintraub, David J. Irwin, Corey T. McMillan

“…The T1 Automated Segmentation of Hippocampal Subfields (ASHS) pipeline was used to compute volume and thickness measurements of MTL subregions in LBD/AD- and LBD/AD+. …”
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Bayesian Ensemble Model with Detection of Potential Misclassification of Wax Bloom in Blueberry Images by Claudia Arellano, Karen Sagredo, Carlos Muñoz, Joseph Govan

“…However, they usually rely on large architectures that could be difficult to implement in the field due to high computational needs. This paper presents a small (only 1502 parameters) Bayesian–CNN ensemble architecture that can be implemented in any small electronic device and is able to classify wax bloom content in images. …”
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Evaluating the Effectiveness of New Criteria for Early Detection of the Start and Intensity of Influenza Epidemics in Russian Federation by L. S. Karpova, M. Yu. Pelikh, K. M. Volik, N. M. Popovtseva, T. P. Stolyarova, D. A. Lioznov

“…The calculation of the baselines was carried out according to the data of the computer database of the Influenza Research Institute on the incidence of influenza by age groups in each city over the previous 5 years in the season from 2016–2017 to 2021–2022.Results. …”
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Highly Sensitive and Specific Panels of Plasma Exosomal microRNAs for Identification of Malignant Pulmonary Nodules by Rui Tao, Dandan Wang, Wenjing Pei, Yanfei Liu, Pengcheng Liu, Renming Li, Jiegou Xu, Jing Ye, Dahai Zhao

“…ABSTRACT Objectives With wide application of computed tomography (CT) in early lung cancer screening, solitary pulmonary nodules (SPNs) are frequently detected. …”
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Revealing the Multi-Target Mechanisms of Fespixon Cream in Diabetic Foot Ulcer Healing: Integrated Network Pharmacology, Molecular Docking, and Clinical RT-qPCR Validation by Tianbo Li, Dehua Wei, Jiangning Wang, Lei Gao

“…RT-qPCR validation in clinical DFU tissue samples demonstrated consistent expression trends with computational predictions: AKT1 was significantly upregulated, while TP53, TNF, IL6, and MAPK1 were markedly downregulated in the Fespixon-treated group compared to controls (<i>p</i> < 0.001), supporting the proposed multi-target therapeutic mechanism. …”
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Long-term mortality outcome of a primary care-based mobile health intervention for stroke management: Six-year follow-up of a cluster-randomized controlled trial. by Xingxing Chen, Enying Gong, Jie Tan, Elizabeth L Turner, John A Gallis, Shifeng Sun, Siran Luo, Fei Wu, Bolu Yang, Yutong Long, Yilong Wang, Zixiao Li, Yun Zhou, Shenglan Tang, Janet P Bettger, Brian Oldenburg, Xiaochen Zhang, Jianfeng Gao, Brian S Mittman, Valery L Feigin, Ruitai Shao, Shah Ebrahim, Lijing L Yan

“…Cox proportional hazards models with cluster-robust standard errors were used to compute hazard ratios (HRs) and 95% confidence intervals (95% CIs), adjusting for town, age, and sex in the main analysis model. …”
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Developing an HIV-specific falls risk prediction model with a novel clinical index: a systematic review and meta-analysis method by Sam Chidi Ibeneme, Eunice Odoh, Nweke Martins, Georgian Chiaka Ibeneme

“…Pooled odds ratios (OR) with 95% confidence intervals (CI) were computed using random-effects models to establish associations between predictors and falls risk. …”
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Effect of Platelet-rich Fibrin on Soft-tissue and Hard-tissue Healing following Surgical Extraction of Mandibular Third Molar: A Prospective Interventional Study by Sudip Chakraborty, Chayan Kundu, Samiran Ghosh, Richi Burman, Avishek De Sarkar, Gourab Mandal, Somak Saha

“…Hard-tissue healing was evaluated using the Cone Beam Computed Tomography (CBCT) findings on the 1st month and 3rd month postoperatively. …”
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Associations among blood heavy metals, neurofilament light chains and cognition function in US adults: NHANES 2013–2014 by YuYan Zhou, YaKun Wang, ChunFang Qiu, YuXuan Man, XiaoNian Zhu, ShengKui Tan, HuaiCai Zeng, XueFeng Guo, ZhengBao Zhang

“…Additionally, generalized linear models (GLMs), weighted quantile sum regression (WQS), Bayesian kernel machine regression (BKMR), quantile-based g computation (qgcomp), and restricted cubic splines (RCS) analyses were employed to examine the associations between heavy metals exposure and sNfL level. …”
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How serious are ‘serious non-specific symptoms (SNSS)’? Evaluation of the introduction of a local SNSS pathway, and the pick-up rate of cancers, within this population by Dominic Maxfield, Alexandra Hickey, Temitope Ade-Onojobi, Rohit Sinha, John Painter, Simon Dunn

“…‘Serious non-specific symptom’ (SNSS) pathways were developed to aid GPs in referring patients with more vague symptoms, concerning for malignancy, that may not already fit into a system specific cancer referral pathway.1Within our Trust, GPs can refer for an urgent computed tomography (CT) chest, abdomen and pelvis, with results reviewed in a weekly multi-disciplinary team (MDT) meeting. …”
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Efficacy of eHealth Interventions for Hemodialysis Patients: Systematic Review and Meta-Analysis by Xu-Hua Zhou, Hui Chen, Weiwei Yang, Li Wang, Lin Chen, Ying Zhu, Yingjun Zhang, Mei Shi, Qin Zhang

“…In the 17 studies, 8 kinds of eHealth intervention delivery formats were used, including text messages, telephone sessions, video, network platforms, social media, computers, websites, and mobile apps. The majority of research studies used a single form of eHealth intervention, and 7 studies adopted a combined approach of 2 or more eHealth technologies. …”
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A rare case of multiple brain abscesses caused by Nocardia abscessus co-infection with tuberculous meningitis in an immunocompetent patient by Xiuri Wang, Lingyan Liang, Yunxiao Liang, Liuyang Hu

“…Additionally, the patient experienced fever, and due to the recurrence of these symptoms, he was admitted to the hospital. Chest computed tomography (CT) scans revealed bilateral pneumonia, and brain magnetic resonance imaging (MRI) strongly suggested the presence of multiple brain abscesses accompanied by meningitis. …”
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