Tagging large CNV blocks in wheat boosts digitalization of germplasm resources by ultra-low-coverage sequencing by Jianxia Niu, Wenxi Wang, Zihao Wang, Zhe Chen, Xiaoyu Zhang, Zhen Qin, Lingfeng Miao, Zhengzhao Yang, Chaojie Xie, Mingming Xin, Huiru Peng, Yingyin Yao, Jie Liu, Zhongfu Ni, Qixin Sun, Weilong Guo

“…Abstract Background The massive structural variations and frequent introgression highly contribute to the genetic diversity of wheat, while the huge and complex genome of polyploid wheat hinders efficient genotyping of abundant varieties towards accurate identification, management, and exploitation of germplasm resources. …”
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Molecular characteristic, evolution, and pathogenicity analysis of avian infectious bronchitis virus isolates associated with QX type in China by Yuanlu Lu, Yiran Zeng, Haowei Luo, Bingchen Qiao, Qi Meng, Zijian Dai, Na Chen, Lingcai Zhao, Xianchen Meng, Haitao Zhang, Jun Xia, Jihui Ping

“…Our data indicate antigenicity variances between QX isolates and QXL87 vaccine strains, potentially resulting in immune evasion occurrences. …”
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Exploring the impact of APOE ɛ4 on functional connectivity in Alzheimer’s disease across cognitive impairment levels by Kangli Dong, Wei Liang, Ting Hou, Zhijie Lu, Yixuan Hao, Chenrui Li, Yue Qiu, Nan Kong, Yan Cheng, Yaqi Wen, Wanyin Ma, Wenbin Zheng, Jitian Guan, Yan Lin, Kai Huang, Lu Zhang, Siya Chen, Xiangyuan Ma, Renhua Wu, Naili Wei

“…Studies have shown that APOE ɛ4 mediates the modulation of intrinsic functional brain networks in cognitively normal individuals and significantly disrupts the whole-brain topological structure in AD patients. However, how APOE ɛ4 regulates brain functional connectivity (FC) and consequently affects the levels of cognitive impairment in AD patients remains unknown. …”
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Understanding the Broad-line Region of Active Galactic Nuclei with Photoionization. I. The Moderate-accretion Regime by Qiaoya Wu, Yue Shen, Hengxiao Guo, Scott F. Anderson, W. N. Brandt, Catherine J. Grier, Patrick B. Hall, Luis C. Ho, Yasaman Homayouni, Keith Horne, Jennifer I-Hsiu Li, Donald P. Schneider

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Prognostic impact of small size sutureless prostheses: results for 241 patients from an international registry by Giuseppe Santarpino, Roberto Lorusso, Giovanni Concistrè, Josè Cuenca Castillo, Vincenzo Argano, Alistair Royse, Angelo Lucas Nobre, Patrick Parrino, Gianluigi Bisleri, Max Baghai, Theodor Fischlein, Giovanni Troise, Generoso Mastrogiovanni, Raphael Fontaine, Davide Pacini, Giuseppe Minniti, Aniello Pappalardo, George Chad Hughes, Philippe Noirhomme, Jean-Philippe Grimaud, Maximilian Scherner, Ignacio Muñoz, George Asimakopoulos, Antony Walker, Daniela Zakova, Michele Torella, Giorgio Vigano, Mark Connolly, Christian Dinges, Pierre Corbi, Loris Salvador, Mauro Rinaldi, Luis Maroto, David Heimansohn, Basel Ramlawi, Mattia Glauber, Jlenia D’Agnano, Valeria Cosco, Veronica D’Anna, Marco Solinas

“…At a maximum follow-up of 8.1 years, 10 cardiovascular deaths, 4 valve related reinterventions (3 structural valve deterioration (SVD) requiring TAVI Valve-in-Valve, 1 endocarditis) occurred. …”
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First-principles study of beryllium thermodynamics and clustering mechanism in molybdenum: Effects of vacancies and self-interstitial atoms by Aoyu Mo, Haijun Li, Fuquan Guo, Xiaowei Ma, Yunshan Xiong, Peng Shao, Bo Li, Kun Jie Yang, Yue-Lin Liu, Quan-Fu Han

“…When the number of Be atoms reaches six, they form an approximately “octahedral” structure, displacing a central Mo atom and generating a Be6V cluster and an SIA. …”
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Applications of Artificial Intelligence in Biotech Drug Discovery and Product Development by Yuan‐Tao Liu, Le‐Le Zhang, Zi‐Ying Jiang, Xian‐Shu Tian, Peng‐Lin Li, Pei‐Huang Wu, Wen‐Ting Du, Bo‐Yu Yuan, Chu Xie, Guo‐Long Bu, Lan‐Yi Zhong, Yan‐Lin Yang, Ting Li, Mu‐Sheng Zeng, Cong Sun

“…It highlights AI's ability to achieve >75% hit validation in virtual screening, design protein binders with sub‐Ångström structural fidelity, enhancing antibody binding affinity to the picomolar range, and optimize nanoparticles to achieve over 85% functionalization efficiency. …”
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Multi-omics insights into antioxidant and immune responses in Penaeus monodon under ammonia-N, low salinity, and combined stress by Yundong Li, Sheng Huang, Song Jiang, Lishi Yang, Jianhua Huang, Qibin Yang, Ziyi Jiang, Jianzhi Shi, Zhenhua Ma, Erchao Li, Falin Zhou

“…Concurrently, gut microbiome analysis demonstrated that ammonia nitrogen stress resulted in a marked increase in Vibrio populations and a significant decrease in Photobacterium, indicating that alterations in microbial community structure are intricately associated with the shrimp stress response. …”
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Dificuldades e Facilidades do processo educativo desenvolvido por enfermeiros às pessoas com estomias [What nurses find difficult and helpful when educating people with ostomies] [... by Vanessa Cristina Maurício, Norma Valéria Dantas de Oliveira Souza, Carlos Eduardo Maurício, Carolina Cabral Pereira da Costa, Marcia de Souza Silva, Anna Beatryz Marques Roque

“…Results: the factors that hampered the educational process were inappropriate physical structure, and scarcity of financial and human resources. …”
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Research on the impact of green finance on China’s ocean economic growth under the “dual carbon” goal by Yan Li, Yan Li, Yi Huang

“…In addition, the stock market activity has a positive contribution from a national perspective, but a negative hindering effect in the Northern Ocean Economic Zone. 3) The gross regional product index, stock market activity, and energy consumption structure in the Northern Ocean Economic Zone have a negative hindering effect, and the gross regional product index has the most negative hindering effect. …”
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The Red Supergiant Progenitor of the Type II Supernova 2024abfl by Jingxiao Luo, Lifu Zhang, Bing-Qiu Chen, Qiyuan Cheng, Boyang Guo, Jiao Li, Yanjun Guo, Jianping Xiong, Xiangcun Meng, Xuefei Chen, Zhengwei Liu, Zhanwen Han

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Fish Diversity Patterns in Rivers Receiving Ecological Water Supplement Driven by Riparian Land Use by LIU Han, LI Lu-dan, GUO Wei-jie, QIAO Qiang-long, GONG Dan-dan, DU Qi, LI Hang, ZHAO Wei-hua

“…Riparian land use types (built area, wetland, trees, crop, water, bare ground, and rangeland) within four buffer zones (0.5 km, 1 km, 2 km, 5 km) were extracted from ESRI’s global 10-m resolution land cover data. Statistical analyses included: Analysis of Variance (ANOVA) and Permutational Multivariate Analysis of Variance (PERMANOVA) to test interannual differences; Non-metric Multidimensional Scaling (NMDS) to visualize community structure; Pearson correlation analysis to examine relationships among diversity indices; and Multiple Linear Regression (MLR) models to quantify the driving effects of riparian land use on fish diversity. …”
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Motives of Freud's essay Das Unheimliche in the collection of stories Žena koja zaustavlja satove by Kornelije Kvas by Lazić-Gavrilović Aleksandra M.

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Evaluation of the innate immunostimulatory potential of originator and non-originator copies of insulin glargine in an in vitro human immune model. by Ernesto Luna, Pankaj Agrawal, Riyaz Mehta, Maria E Boone, Charlotte Vernhes, Colombe Denys, Robert Small, Bhaswati Mukherjee, Norbert Tennagels, Stefan Maerten, Donald R Drake

“…<h4>Background</h4>The manufacture of insulin analogs requires sophisticated production procedures which can lead to differences in the structure, purity, and/or other physiochemical properties of resultant products that can affect their biologic activity. …”
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Validation of Quantitative Ultrasound and Texture Derivative Analyses-Based Model for Upfront Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer by Adrian Wai Chan, Lakshmanan Sannachi, Daniel Moore-Palhares, Archya Dasgupta, Sonal Gandhi, Rossanna Pezo, Andrea Eisen, Ellen Warner, Frances C. Wright, Nicole Look Hong, Ali Sadeghi-Naini, Mia Skarpathiotakis, Belinda Curpen, Carrie Betel, Michael C. Kolios, Maureen Trudeau, Gregory J. Czarnota

“…Explanations for the misclassified cases included unplanned modifications made to the type of chemotherapy during treatment, inherent limitations of the predictive model, presence of DCIS in tumour structure, and an ill-defined tumour border in a minority of cases. …”
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Genome-Wide Identification of <i>G3BP</i> Family in U’s Triangle <i>Brassica</i> Species and Analysis of Its Expression in <i>B. napus</i> by Alain Tseke Inkabanga, Qiheng Zhang, Shanshan Wang, Yanni Li, Jingyi Chen, Li Huang, Xiang Li, Zihan Deng, Xiao Yang, Mengxin Luo, Lingxia Peng, Keran Ren, Yourong Chai, Yufei Xue

“…We then analyzed their gene structure, protein motifs, gene duplication type, phylogeny, subcellular localization, SSR loci, and upstream miRNAs. …”
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Bacteroides uniformis-generated hexadecanedioic acid ameliorates metabolic-associated fatty liver disease by Da-Ya Zhang, Da Li, Shi-Ju Chen, Li-Jun Zhang, Xu-Li Zhu, Fa-Di Chen, Chen Chen, Qi Wang, Yiping Du, Jian-Xin Xiong, Shi-Mei Huang, Xiao-Dong Zhang, Yan-Ting Lv, Fan Zeng, Run-Xiang Chen, Xianfeng Huang, Fengjiao Mao, Shuo Zhou, Qicen Yao, Yuliang Huang, Runyu Chen, Ying Mo, Yunqian Xie, Yue-Hong Jiang, Zhai Chen, Cui-Yi Mo, Jia-Jia Chen, Fei-Hu Bai

“…Distinct differences were identified in both the microbial community structure and metabolomic profiles between MAFLD patients and healthy controls. …”
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Correlates of duration between initial drug use and first drug injection among people who inject drugs in Iran, 2020 by Zahra Abdolahinia, Zahra Jaafari, Ali Karamoozian, Soheil Mehmandoost, Nima Ghalekhani, Mehrdad Khezri, Ghazal Mousavian, Mostafa Shokoohi, Ali Mirzazadeh, Ali Akbar Haghdoost, Mohammad Karamouzian, Mohammad Mehdi Gooya, Samaneh Akbarpour, Hamid Sharifi, Fatemeh Tavakoli

“…Policymakers should prioritize evidence-based, multi-faceted approaches that target both individual and structural factors to delay or prevent the transition to injection drug use and reduce associated health risks.…”
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Cluster Candidates with Massive Quiescent Galaxies at z ∼ 2 by Tomokazu Kiyota, Makoto Ando, Masayuki Tanaka, Alexis Finoguenov, Sadman Shariar Ali, Jean Coupon, Guillaume Desprez, Stephen Gwyn, Marcin Sawicki, Rhythm Shimakawa

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The pattern of state organization in the new constitution of Lithuania: A third way between the presidential and parliamentary systems? by Andreas Hollstein

“…If not—how could such a structure be classified? The author compares the data he has arranged in the second part with the premises of theoretical patterns. …”
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