Resveratrol supplementation improves productivity and health in heat-stressed lactating Holstein cows by M.R.R. Nair, K. Frady, Z. Yu, J.M. Cantet, M.S. Hasan, A.G. Ríus

“…Fixed effects included main effects of treatment, parity, day, time, and all possible interactions with day and time as repeated measures, and animal was included as a random effect. The autoregressive structure was used based on the lower Akaike and Bayesian information criteria. …”
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Comparative Analysis of Fecal Microbiota and Metabolomic Profiles in Male and Female Leizhou Goats Offered a 10% Crude Protein Diet Among Four Energy Levels by Hu Liu, Wenji Wang, Weishi Peng, Anmiao Chen, Xiaogao Diao, Xia Yang, Jianmin Chai, Yuanting Yang, Ke Wang, Jiancheng Han, Hanlin Zhou

“…Therefore, to investigate the differences in the structure and function of the gut microbiota between female and male goats, we analyzed their fecal microbiota and metabolites when fed a 10% crude protein diet at four different energy levels—7.01, 8.33, 9.66, and 10.98 MJ/kg DM. …”
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Skin mastocytoma in dogs, complex treatment and survival of animals by B. B. Ivashkiv, A. R. Mysak

“…It was established that in the structure of skin tumor lesions in dogs, MCTs reach 17.2 %. …”
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The effect of age and sex on brain metabolites: from childhood to adulthood by María Ortuño, Adriana Fortea, Isabel Valli, Emma Muñoz-Moreno, Roger Borràs, Irene Martínez-Serrano, Mireia Masias Bruns, Patricia Camprodon-Boadas, Enric Vilajosana, Lydia Fortea, Joaquim Raduà, Elena de la Serna, Inmaculada Baeza, Josefina Castro-Fornieles, Gisela Sugranyes

“…This cross-sectional study set out to examine the relationship between levels of neurometabolites and age and sex —key modulators of brain function and structure—, continuously from childhood to early adulthood, in areas relevant to the study of psychiatric disorders.Magnetic resonance spectroscopy (¹H MRS) data was acquired in the dorsomedial prefrontal region (dmPF) and the medial temporal lobe (mTL) in 128 healthy individuals aged 7 to 34 years, 68.5 % females (ndmPF = 124; nmTL = 75). …”
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Better public housing management in Ghana by Samson Aziabah

“…The HM approach highlights and recommends a defined structure to manage public houses. The actors in the structure include the district assembly, the coordinating director, the housing unit, the works department, and tenants, whose roles, responsibilities, and relationships are clearly defined. …”
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Integrated multi-omics profiling reveals the role of the DNA methylation landscape in shaping biological heterogeneity and clinical behaviour of metastatic melanoma by Andrea Anichini, Francesca P. Caruso, Vincenzo Lagano, Teresa M. R. Noviello, Rossella Tufano, Gabriella Nicolini, Alessandra Molla, Ilaria Bersani, Francesco Sgambelluri, Alessia Covre, Maria F. Lofiego, Sandra Coral, Anna Maria Di Giacomo, Elena Simonetti, Barbara Valeri, Mara Cossa, Filippo Ugolini, Sara Simi, Daniela Massi, Massimo Milione, Andrea Maurichi, Roberto Patuzzo, Mario Santinami, Michele Maio, Michele Ceccarelli, Roberta Mortarini, On behalf of the EPigenetic Immune-oncology Consortium Airc (EPICA) investigators

“…Abstract Background We developed an integrated multi-omics analysis in metastatic melanoma (MM) cohorts to associate DNA methylation profiles with tumor progression, survival, response to adjuvant immunotherapy, structure of the tumor immune microenvironment and transcriptional programs of immunity and melanoma differentiation. …”
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Gonadal Histology and Expression Analysis of Sex Characteristic Genes in Grass Carp at Different Ages by Bo QI, Shengjie LI, Jinxing DU, Xiaofang XIAO, Dongyun ZHANG, Tao ZHU, Caixia LEI, Zhijun LIU, Hongmei SONG

“…Anti-Müllerian hormone (amh) regulates the structure of reproductive organs and the differentiation and development of reproductive cells. …”
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Probiotics improve eggshell quality via regulating microbial composition in the uterine and cecum by Yuxiang Lu, Hengyong Xu, Zhi Hu, Dan Li, Alma Rustempasic, Yuxin Zhou, Qingqing Deng, Jiaxue Pu, Xiaoling Zhao, Yao Zhang, Yiping Liu, Yan Wang

“…Furthermore, the changes of these phenotypes are closely related to the microbial structure of the uterus and cecum. Overall, the data suggest that dietary probiotics improved uterine and cecal microbiota, optimized egg quality, eggshell quality, uterus development, and regulated mineralization gene expression and ion content in serum and eggshell, thereby improving productivity of laying hens. …”
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The global spectrum of tree crown architecture by Tommaso Jucker, Fabian Jörg Fischer, Jérôme Chave, David A. Coomes, John Caspersen, Arshad Ali, Grace Jopaul Loubota Panzou, Ted R. Feldpausch, Daniel Falster, Vladimir A. Usoltsev, Toby D. Jackson, Stephen Adu-Bredu, Luciana F. Alves, Mohammad Aminpour, Bhely Angoboy Ilondea, Niels P. R. Anten, Cécile Antin, Yousef Askari, Narayanan Ayyappan, Lindsay F. Banin, Nicolas Barbier, John J. Battles, Hans Beeckman, Yannick E. Bocko, Ben Bond-Lamberty, Frans Bongers, Samuel Bowers, Michiel van Breugel, Arthur Chantrain, Rajeev Chaudhary, Jingyu Dai, Michele Dalponte, Kangbéni Dimobe, Jean-Christophe Domec, Jean-Louis Doucet, Juan Manuel Dupuy Rada, Remko A. Duursma, Moisés Enríquez, Karin Y. van Ewijk, William Farfán-Rios, Adeline Fayolle, Marco Ferretti, Eric Forni, David I. Forrester, Hammad Gilani, John L. Godlee, Matthias Haeni, Jefferson S. Hall, Jie-Kun He, Andreas Hemp, José L. Hernández-Stefanoni, Steven I. Higgins, Robert J. Holdaway, Kiramat Hussain, Lindsay B. Hutley, Tomoaki Ichie, Yoshiko Iida, Hai-Sheng Jiang, Puspa Raj Joshi, Hasan Kaboli, Maryam Kazempour Larsary, Tanaka Kenzo, Brian D. Kloeppel, Takashi S. Kohyama, Suwash Kunwar, Shem Kuyah, Jakub Kvasnica, Siliang Lin, Emily R. Lines, Hongyan Liu, Craig Lorimer, Jean-Joël Loumeto, Yadvinder Malhi, Peter L. Marshall, Eskil Mattsson, Radim Matula, Jorge A. Meave, Sylvanus Mensah, Xiangcheng Mi, Stéphane T. Momo, Glenn R. Moncrieff, Francisco Mora, Rodrigo Muñoz, Sarath P. Nissanka, Zamah Shari Nur Hajar, Kevin L. O’Hara, Steven Pearce, Raphaël Pelissier, Pablo L. Peri, Pierre Ploton, Lourens Poorter, Mohsen Javanmiri Pour, Hassan Pourbabaei, Sabina C. Ribeiro, Casey Ryan, Anvar Sanaei, Jennifer Sanger, Michael Schlund, Giacomo Sellan, Alexander Shenkin, Bonaventure Sonké, Frank J. Sterck, Martin Svátek, Kentaro Takagi, Anna T. Trugman, Matthew A. Vadeboncoeur, Ahmad Valipour, Mark C. Vanderwel, Alejandra G. Vovides, Peter Waldner, Weiwei Wang, Li-Qiu Wang, Christian Wirth, Murray Woods, Wenhua Xiang, Fabiano de Aquino Ximenes, Yaozhan Xu, Toshihiro Yamada, Miguel A. Zavala, Niklaus E. Zimmermann

“…Yet despite the importance of crown architecture in shaping the structure and function of terrestrial ecosystems, we lack a complete picture of what drives this incredible diversity in crown shapes. …”
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Incidence, clinical and genomic trends of hospital- and Non-hospital-onset KPC-producing Klebsiella pneumoniae infections before and during the COVID-19 era: a ten-year interrupted... by Manuel Recio-Rufián, Teresa López-Viñau, Víctor Gálvez-Soto, Ángela Cano, Rafael Ruiz-Montero, Belén Gutiérrez-Gutiérrez, Irene Gracia-Ahufinger, Germán Peñalva, Juan Antonio Marín-Sanz, Miriam Marín-Sanz, David Segorbe, Juan Jesús Pineda-Capitán, Montserrat Muñoz-Rosa, Cristina Riazzo, Federico Giovagnorio, Elisa Ruiz-Arabi, José David Torres-Peña, Juan José Castón, Isabel Machuca, Inmaculada Salcedo-Leal, Luis Martínez-Martínez, Elena Pérez-Nadales, Julián Torre-Cisneros, KLEBMAN study group

“…Whole-genome sequencing and PERMANOVA evaluated the genomic structure of ST512/KPC-3 isolates. Multivariable regression analysed the association between infection type and clinical outcomes. …”
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Unearthing the climate history of the Atacama Desert in northern Chile – deep drilling in two clay pans of the Coastal Cordillera by V. Wennrich, J. Diederich-Leicher, B. N. Blanco-Arrué, B. N. Blanco-Arrué, C. Büttner, S. Buske, E. Campos Sepulveda, T. Dunai, J. Feller, E. Galego, A. Hasberg, N. Leicher, D. A. López, J. Maldonado, A. Medialdea, A. Medialdea, L. Ninnemann, L. Ninnemann, R. Perryman, J. C. Ríos-Contesse, B. Ritter, S. Scheidt, B. Vargas-Machuca, P. Yogeshwar, P. Yogeshwar, M. Melles

“…Electromagnetic and seismic surveys yielded a three-layer structure in both basins consisting of the resistive basement overlain by a low-resistivity basal and a high-resistivity upper sediment unit with total sediment thicknesses of more than <span class="inline-formula">∼</span> 100 and <span class="inline-formula">∼</span> 160 m in the Playa Adamito Grande (PAG) and Paranal clay pans, respectively. …”
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Complex Variation in Afrotropical Mammal Communities With Human Impact by Deogratias Tuyisingize, Lars Kulik, Delagnon Assou, Diorne Zausa, Solange Kamga, Onella Mundi, Stefanie Heinicke, Inza Kone, Samedi Jean Pierre Mucyo, Tenekwetche Sop, Christophe Boesch, Colleen Stephens, Anthony Agbor, Samuel Angedakin, Emma Bailey, Mattia Bessone, Charlotte Coupland, Josephine Head, Tobias Deschner, Paula Dieguez, Villard Ebot Egbe, Anne‐Céline Granjon, Thurston Cleveland Hicks, Sorrel Jones, Ammie K. Kalan, Kevin E. Langergraber, Juan Lapuente, Kevin C. Lee, Laura K. Lynn, Nuria Maldonado, Maureen S. McCarthy, Amelia Meier, Lucy Jayne Ormsby, Alex K. Piel, Lilah Sciaky, Volker Sommer, Fiona A. Stewart, Erin G. Wessling, Jane Widness, Roman M. Wittig, Pauline Strohbach, Mimi Arandjelovic, Yntze van derHoek, Hjalmar S. Kühl

“…We assessed variation in the structure and composition of Afrotropical medium and large mammal communities within and outside protected areas, and under varying human impact. …”
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Splicing defect of StDRO2 intron 1 promotes potato root growth by disturbing auxin transport to adapt to drought stress by Jianping Zhao, Baolin Yao, Ziai Peng, Xinyue Yang, Kuixiu Li, Xiaoyan Zhang, Haiyan Zhu, Xuan Zhou, Meixian Wang, Lihui Jiang, Xie He, Yan Liang, Xiaoping Zhan, Xiaoran Wang, Yuliang Dai, Yanfen Yang, Ao Yang, Man Dong, Suni Shi, Man Lu, Yi Zhao, Mingyun Shen, Liwei Guo, Changning Liu, Hongji Zhang, Decai Yu, Yunlong Du

“…Furthermore, the secondary structure of StDRO2 mRNA analyzed with RNAfold WebServer was altered in the dro2 mutant. …”
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A 50 s Quasiperiodic Oscillation in the Early X-Ray Afterglow of GRB 220711B by H. Gao, W.-H. Lei, S. Xiao, Z.-P. Zhu, L. Lan, S.-K. Ai, A. Li, N. Xu, T.-C. Wang, B. Zhang, D. Xu, J. P. U. Fynbo, K. E. Heintz, P. Jakobsson, D. A. Kann, S.-Y. Fu, S.-Q. Jiang, X. Liu, S.-L. Xiong, W.-X. Peng, X.-B. Li, W.-C. Xue

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Antimicrobial resistance (AMR) and spread of New Delhi Metallo-β-Lactamase (NDM) in Italy: A call for policymakers by Gabriella Nucera

“…According to its Agenzia Regionale di Sanità (ARS) data, between November 2018 and 27 October 2019, NDM producing CREs have been identified in the blood of 129 patients and the rate of mortality in patients with sepsis was as 33% [13]. …”

Hemoglobin state-flux: A finite-state model representation of the hemoglobin signal for evaluation of the resting state and the influence of disease. by Randall L Barbour, Harry L Graber, San-Lian S Barbour

“…Inspection of the coefficient arrays reveals that they are governed predominantly by first-order rate processes, and that each array class exhibits preferred structure that is mainly independent of the others. …”
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Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…Two reviewers extracted data independently using a piloted data extraction form. …”
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The Knee-SCHOOL: a brief patient-centered multidisciplinary educational program for knee osteoarthritis by Denise Vianna Machado Ayres, Sabrina Saemy Tome Uchiyama, Andréa Oliveira Prates, Rosana Aparecida Freitas Lopes, Antenor Bispo Santos Silva, Denise Rodrigues Tsukimoto, Rosimeire Alves Amorim, Taynah Souza Ribeiro, Artur Cesar Aquino Santos, André Tadeu Sugawara, André Tadeu Sugawara, Marcos Montagnini, Linamara Rizzo Battistella, Linamara Rizzo Battistella, Marta Imamura, Marta Imamura

“…BackgroundKnee osteoarthritis (KOA) is the most common form of arthritis in adults and a leading cause of years lived with disability, representing a significant burden on healthcare worldwide.ObjectiveDescribe the structure and educational elements of the Knee-SCHOOL, a brief patient-centered multidisciplinary educational program for patients with KOA.DesignObservational prospective study.SettingAcademically affiliated rehabilitation outpatient center in Brazil.MethodsThe program consisted of three in-person educational sessions (4.5 hr each) for 55 community dwelling adults, aged ≥50 years, with primary KOA-related pain. …”
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Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity by Stephane Isnard, Stephane Isnard, Tsoarello Mabanga, Tsoarello Mabanga, Léna Royston, Léna Royston, Léna Royston, Carolina A. Berini, Carolina A. Berini, Simeng Bu, Simeng Bu, Orthy Aiyana, Orthy Aiyana, Hansen Feng, Hansen Feng, Bertrand Lebouché, Bertrand Lebouché, Bertrand Lebouché, Bertrand Lebouché, Cecilia T. Costiniuk, Cecilia T. Costiniuk, Joseph Cox, Joseph Cox, Guido Kroemer, Guido Kroemer, Guido Kroemer, Madeleine Durand, Jean-Pierre Routy, Jean-Pierre Routy, Jean-Pierre Routy, the Biobanque Québécoise de la COVID-19 (BQC-19)

“…Autophagy, a cytosolic structure degradation pathway is involved in the maintenance of cellular homeostasis, degradation of intracellular pathogens and generation of energy for immune responses. …”
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Dark Matter Distinguished by Skewed Microlensing in the “Dragon Arc” by Tom Broadhurst, Sung Kei Li, Amruth Alfred, Jose M. Diego, Paloma Morilla, Patrick L. Kelly, Fengwu Sun, Masamune Oguri, Hayley Williams, Rogier Windhorst, Adi Zitrin, Katsuya T. Abe, Wenlei Chen, Liang Dai, Yoshinobu Fudamoto, Hiroki Kawai, Jeremy Lim, Tao Liu, Ashish K. Meena, Jose M. Palencia, George F. Smoot, Liliya L.R. Williams

“…This asymmetry, we argue, follows from the parity difference in caustic structure inherent to microlensing that extends to higher magnification in the negative parity regions. …”
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