Global characterization of mouse testis O-glycoproteome landscape during spermatogenesis by Qiannan Liu, Xiaoyan Lu, Yao Deng, Han Zhang, Rumeng Wei, Hongrui Li, Ying Feng, Juan Wei, Fang Ma, Yan Zhang, Xia Zou

“…Interestingly, we found dynamic changes with an increase Tn and a decrease T structure from early to mature developmental stages. …”
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New Insights into the Phylogeographic History of <i>Dirofilaria immitis</i> in the Canary Islands, Spain by Rodrigo Morchón, Alfonso Balmori-de la Puente, Manuel Collado-Cuadrado, Iván Rodríguez-Escolar, Noelia Costa-Rodríguez, Elena Infante González-Mohino, Elena Carretón, José Alberto Montoya-Alonso

“…To obtain a more complete understanding of its evolutionary history, structure and genomic diversity, comparative studies using next-generation sequencing data from endemic areas are needed, which will help in the long term to implement monitoring and control measures in a given area and to better understand its global phylogeographic history.…”
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Nipocalimab, an immunoselective FcRn blocker that lowers IgG and has unique molecular properties by Nilufer P. Seth, Rui Xu, Matthew DuPrie, Amit Choudhury, Samuel Sihapong, Steven Tyler, James Meador, William Avery, Edward Cochran, Thomas Daly, Julia Brown, Laura Rutitzky, Lynn Markowitz, Sujatha Kumar, Traymon Beavers, Sayak Bhattacharya, Hsin Chen, Viraj Parge, Karen Price, Yang Wang, Siddharth Sukumaran, Yvonne Pao, Katie Abouzahr, Fiona Elwood, Jay Duffner, Sucharita Roy, Pushpa Narayanaswami, Jonathan J. Hubbard, Leona E. Ling

“…Here, we present the molecular, cellular, and nonclinical characteristics of nipocalimab that support the reported clinical pharmacology and potential clinical application in IgG-driven, autoantibody- and alloantibody-mediated diseases. The crystal structure of the nipocalimab antigen binding fragment (Fab)/FcRn complex reveals its binding to a unique epitope on the IgG binding site of FcRn that supports the observed pH-independent high-binding affinity to FcRn. …”
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Cu‐Co Dual Sites Tandem Synergistic Effect Boosting Neutral Low Concentration Nitrate Electroreduction to Ammonia by Wenhao Yang, Ziwei Chang, Xu Yu, Ping Wu, Ruxiang Shen, Lianzhou Wang, Xiangzhi Cui, Jianlin Shi

“…The designed Cu‐CoP catalyst exhibits an ammonia yield of 7.65 mg h−1 cm−2 and a Faraday efficiency of 85.1% at −1.0 V under neutral low‐concentration nitrate (10 m M), which is the highest ammonia yield in the reported data. In situ characterization and theoretical calculations confirm the tandem synergistic effect, in which the Cu site favors the adsorption and activation of NO3− to form NO2−, and concurrently modulates the electronic structure of the Co site with optimized Hads adsorption resulting in the significantly enhanced NO3−RR at neutral low concentration nitrate.…”
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Microwave-Assisted pyrolysis of waste plastics: A comprehensive review on process parameters, catalysts, and future prospects by K. M. Oajedul Islam, Nabeel Ahmad, Aniz Chennampilly Ummer, Usama Ahmed, Mohammad Nahid Siddiqui, Marcos Millan, Abdul Gani Abdul Jameel

“…Special emphasis is placed on co-feeding strategies, hydrogen production, and the influence of catalyst structure on aromatic yield. Key challenges—such as hot spot formation, catalyst deactivation, and scale-up limitations—are identified. …”
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X-Ray Polarization Variability during a Few Hz Quasiperiodic Oscillations in Swift J1727.8-1613 Observed with IXPE by Kaito Ninoyu, Shinya Yamada, Yuusuke Uchida, Taichi Igarashi, Ryota Hayakawa, Takayoshi Kohmura

“…X-ray polarization observation in wide band provides further understanding of the geometry and magnetic field structure of the accretion flows near the black hole.…”
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Highly porous single-phase rhombohedral CrxRh2−xO3 nanofibers expediting oxygen evolution reaction by Taehui Kwon, Kyungmin Kim, Sampath Prabhakaran, Subin Choi, Jiwon Kim, Yeji Yim, Jihyun Park, Hoi Ri Moon, Myung Hwa Kim, Do Hwan Kim, Youngmi Lee

“…Single-phase CrxRh2−xO3 could then induce the best synergistic effect of Cr and Rh owing to the perturbation of the surface electronic structure of the electrocatalyst active site and much enlarged electroactive surface area. …”
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Predicting Performance of Hall Effect Ion Source Using Machine Learning by Jaehong Park, Guentae Doh, Dongho Lee, Youngho Kim, Changmin Shin, Su‐Jin Shin, Young‐Chul Ghim, Sanghoo Park, Wonho Choe

“…Herein, a robust machine learning model is introduced that uses a neural network ensemble to predict the performance of Hall effect ion sources based on design parameters such as discharge channel dimensions and magnetic field structure. The neural networks are trained using 18 000 data points generated from numerical simulations with input powers ranging from sub‐kW‐ to kW‐class. …”
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Human adaptation and diversification in the Microsporum canis complex by Xin Zhou, Sarah A. Ahmed, Chao Tang, Maria Eduarda Grisolia, José Francisco Ghignatti Warth, Kristen Webster, Andrea Peano, Silke Uhrlass, Claudia Cafarchia, Marie Pierre Hayette, Rosalie Sacheli, Tadeja Matos, Yingqian Kang, G. Sybren de Hoog, Peiying Feng

“…To clarify the evolutionary relationship between the three species and explore the potential host shift process, this study used phylogenetic analysis, population structure analysis, multispecies coalescent analyses, determination of MAT idiomorph distribution, sexual crosses, and macromorphology and physicochemical features to address the above questions. …”
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Artificial intelligence for microgrids design, control, and maintenance: A comprehensive review and prospects by Mojtaba Hadi, Elhoussin Elbouchikhi, Zhibin Zhou, Abdelhakim Saim, Miadreza Shafie-khah, Pierluigi Siano, Hesam Rahbarimagham, Pau Marti Colom

“…This paper begins by exploring the fundamentals of microgrids, emphasizing their structure, components, and control aspects. After introducing essential AI techniques, it analyzes their role in various microgrid domains, such as design, control, and maintenance. (1) In the design realm, the focus is on optimal sizing. (2) In the realm of control, a hierarchical framework comprising primary, secondary, and tertiary levels is introduced. …”
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Cancer-associated VEGFR2R1032Q sustains receptor activation also by promoting ligand-independent hetero-dimerization with co-expressed wild-type VEGFR2 and translocation into lipid... by Cosetta Ravelli, Michela Corsini, Roberto Bresciani, Angela M. Rizzo, Luca Zammataro, Paola A. Corsetto, Elisabetta Grillo, Stefania Mitola

“…This was associated with reduced mobility of the receptor on the membrane, linked to its translocation into detergent-resistant membrane (DRM) domains (e.g. lipid rafts), which showed alterations in lipid compositions and structure. These data shed light on a novel oncogenic mechanism of activation of VEGFR2, clarifying the paradoxical loss-of-function nature of the substitution R1032Q of VEGFR2.…”
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Main factors of primary arterial hypertension development and pathogenesis in young, call-up-aged men with complicated family anamnesis by V. A. Lusov, E. M. Evsikov, Yu. M. Mashukova, T. V. Kotov, N. O. Kugaenko, N. E. Ivakhnenko, T. B. Salova

“…Hemodynamics was assessed by blood pressure (BP) office measurement and ambulatory monitoring, together with B-mode echocardiography data. Renal and renourinal structure and function was assessed by static and dynamic scintigraphy, renal ultrasound, renal radiography, excretory urography, color Doppler angiography of renal arteries, measurement of microalbuminuria in morning urine and glomerular filtration rate by endogenous creatinine. …”
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Identification of novel ABCB4 variants and genotype-phenotype correlation in progressive familial intrahepatic cholestasis type 3 by Senyan Wang, Qi Liu, Xiaoyan Sun, Wenjuan Wei, Leilei Ding, Xiaofang Zhao

“…The study included statistical analysis of clinical information, genetic analysis, multi-species sequence alignment, protein structure modeling, and pathogenicity assessment. Machine learning techniques were applied to identify genotype-phenotype relationships. …”
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Microbial micronutrient sharing, gut redox balance and keystone taxa as a basis for a new perspective to solutions targeting health from the gut by Robert E. Steinert, Ateequr Rehman, Mehdi Sadaghian Sadabad, Alessio Milanese, Jonas Wittwer-Schegg, Jeremy P. Burton, Anneleen Spooren

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Curlometer and gradient techniques: past and future applications by M. W. Dunlop, M. W. Dunlop, H.-S. Fu, C. Shen, X. Tan, X.-C. Dong, Y.-Y. Yang, P. Robert, C. P. Escoubet

“…Nevertheless, the techniques can be reliable in many magnetospheric regions where time stationarity is largely applicable, or when properties of the morphology can be assumed (for example, the expected orientation of underlying large-scale structure). Many magnetospheric regions have been investigated directly (illustrated here by the magnetopause, ring current and field-aligned currents at high and low altitudes), and options for variable numbers of spacecraft have been considered. …”
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Association between tongue position and Dentofacial skeletal patterns: a simplified approach to tongue position assessment by Jun Sun, Rugan Su, Yu Guo, He Li, Zhuojun Xu, Yuxin Zhang, Hongwan Na, Yanning Ma, Song Li

“…Abstract Background Tongue position plays a vital role in craniofacial development, influencing skeletal structure and dental alignment. This study aims to assess tongue position and investigate its relationship with various dentofacial skeletal patterns using a novel cephalometric analysis method. …”
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Study on the role of tissue-specific and non-specific autoantibodies, matrix metalloproteinase-3 and neuron-specific enolase enzymes in the exacerbation of autoimmune thyroiditis by R. R. Rahimova, A. M. Efendiyev, I. J. Shahverdiyeva, G. S. Dashdamirova, S. R. Guliyeva, U. H. Azizova

“…Elevated titers of anti-DNA autoantibodies may indicate an aggravation of the autoimmune process due to cellular structure damage, resulting in gland dysfunction. The findings also suggest that metalloproteinase-3, a marker predicting thyroid tissue damage, may negatively impact the immune response induction, ultimately affecting the activity of neuron-specific enolase. …”
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Creating and sustainable development of specialized centers as a way to improve quality of medical care by V. I. Guzeva, O. V. Guzeva, V. V. Guzeva, D. O. Dukhanina, V. R. Kasumov

“…The accumulated experience in the Center confirms the relevance of the creation of the structure of scientific and educational institutions specialized centers in which patients will be given to high-quality medical care.…”
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Recyclable nano-CuI immobilized on UiO-66-NH2 coated with porous sodium alginate-polysulfonamide for synthesis of phenols by Samaneh Koosha, Ramin Ghorbani-Vaghei, Sedigheh Alavinia

“…FESEM images revealed spherical sodium alginate particles and TEM analysis indicated a core-shell structure. ICP data confirmed the anchoring of 0.67 mol% of copper iodide. …”
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Validation of the World Health Organization’s Disability Assessment Schedule 2.0 for children with mental disorders in specialized health-care services by Lina Díaz-Castro, Miriam Arroyo-Belmonte, Paloma Suárez-Brito, María Elena Márquez-Caraveo, Consuelo Garcia-Andrade

“…Exploratory factor analysis revealed a six-dimensional structure, with gender-specific differences identified in functional impairment patterns.DiscussionThe study provides robust evidence supporting the utility and psychometric properties of the WHODAS 2.0 for assessing functional impairment in children and adolescents with mental disorders in Mexican psychiatric hospitals. …”
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