Factors of coxitis progression in patients with axial spondyloarthritis. Results of a two-year dynamic observation by E. M. Agafonova, Sh. Erdes, T. V. Dubinina, A. B. Demina, A. V. Smirnov

“…It is also worth noting that the relationship between laboratory parameters of inflammation and disease activity indices is relatively weak, as well as with structural damage in axSpA.Conclusion. Factors influencing the development and progression of coxitis in axSpA are a combination of such signs as high clinical activity of the disease, the presence of peripheral arthritis and male gender.…”
Get full text

Immobilization of Oat Bran Polyphenols in Complex Coacervates of Whey Protein and Malthodextrin by Zyaitdinov Damir R., Ewteew Alexandr V., Bannikova Anna V.

“…In vitro enzymatic hydrolysis protocol simulating digestion in the gastrointestinal tract was used to study the effect of capsule structural characteristics on the kinetics of polyphenol release. …”
Get full text

Probabilistic Modelling of Fatigue Behaviour of 51CrV4 Steel for Railway Parabolic Leaf Springs by Vítor M. G. Gomes, Felipe K. Fiorentin, Rita Dantas, Filipe G. A. Silva, José A. F. O. Correia, Abílio M. P. de Jesus

“…The longevity of railway vehicles is an important factor in their mechanical and structural design. Fatigue is a major issue that affects the durability of railway components, and therefore, knowledge of the fatigue resistance characteristics of critical components, such as the leaf springs, must be extensively investigated. …”
Get full text

Spontaneous Intracranial Hypotension and Dural Ectasia in Marfan Syndrome: An Illustrative Case Successfully Treated with Steroid Therapy and Literature Review by Francesco Signorelli, Omar Ktari, Ludovico Agostini, Giorgio Ducoli, Fabio Zeoli, Massimiliano Visocchi

“…Patients with Marfan Syndrome (MS) and other connective tissue disorders are at an increased risk for dural ectasia, which may predispose them to spontaneous CSF leaks due to the structural weakness of their dural membranes. The management of SIH in MS patients is debated. …”
Get full text

Genome-Wide Analysis of Caffeoyl-CoA-O-methyltransferase (CCoAOMT) Family Genes and the Roles of <i>GhCCoAOMT7</i> in Lignin Synthesis in Cotton by Lina Ma, Jin Wang, Kaikai Qiao, Yuewei Quan, Shuli Fan, Liqiang Wu

“…Motif analysis revealed that all CCoAOMT proteins possess conserved Methyltransf_3 domains, and conserved structural features were identified based on the genes’ exon-intron organization. …”
Get full text

Drying kinetics and quality characteristics of ultrasound-assisted germination of quinoa grains: A study on functional properties, mineral content and bioactive compounds by Jabir Khan, Yang Li, Palwasha Gul, Qingyun Li, Kunlun Liu

“…This study evaluated functional properties, minerals, bioactive compounds and structural properties of Pre-treatments assisted germination of quinoa grains JQ-778 including, Only germinated seeds (OGS), soaked germinated seeds (SGS), ultrasound at 28 &amp; 40 frequencies (US 28 kHz &amp; US 40 kHz) for 30 min in a Biochemical-Incubator of 96-hour period at 25 °C, 12/12 h dark and light circle, followed by drying at temperatures 50 °C, 60 °C, 70 °C &amp; combined (70, 60, 50 °C). …”
Get full text

The mediating effect of the budget process on the performance of small- and medium-sized enterprises in Ho Chi Minh City, Vietnam by Vuong Khanh Tuan, Premkumar Rajagopal

“…Structural equation modelling (SEM) was used to test both the conceptual framework and the hypothesis of the real study. …”
Get full text

Construction of Clinical Predictive Models for Heart Failure Detection Using Six Different Machine Learning Algorithms: Identification of Key Clinical Prognostic Features by Qu FZ, Ding J, An XF, Peng R, He N, Liu S, Jiang X

“…Fang Zhou Qu,1 Jiang Ding,2 Xi Feng An,3 Rui Peng,4 Ni He,5 Sheng Liu,1 Xin Jiang5 1Medical School, Xizang Minzu University, Xianyang, People’s Republic of China; 2Institute of Electrical Power Systems, Graz University of Technology, Graz, Austria; 3The First Affiliated Hospital of Jinan University, Guangzhou, People’s Republic of China; 4Affiliated Nanhua Hospital, University of South China, Hengyang, People’s Republic of China; 5Department of Cardiology, Shaanxi Provincial People’s Hospital, Xi’an, People’s Republic of ChinaCorrespondence: Xin Jiang, Department of Cardiology, Shaanxi Provincial People’s Hospital, Xi’an, Shanxi Province, People’s Republic of China, Email 18560453060@163.comPurpose: Heart failure (HF) is a clinical syndrome in which structural or functional abnormalities of the heart result in impaired ventricular filling or ejection capacity. …”
Get full text

Strengthening health system's capacity for pre-exposure prophylaxis for adolescent girls and young women and adolescent boys and young men in South Africa (SHeS'Cap-PrEP): Protocol... by Edward Nicol, Trisha Ramraj, Mbuzeleni Hlongwa, Wisdom Basera, Ngcwalisa Jama, Carl Lombard, Tracy McClinton-Appollis, Darshini Govindasamy, Desiree Pass, Noluntu Funani, Sarah Aheron, Ariana Paredes-Vincent, Jennifer Drummond, Mireille Cheyip, Sibongile Dladla, Jason Bedford, Cathy Mathews

“…In South Africa, various approaches of delivering PrEP have been adopted at different service delivery points (facility-based only, school-based only, community-based only and hybrid school-facility and community-facility models) to overcome challenges associated with individual, structural, and health systems related barriers that may hinder access to and uptake of PrEP among these populations. …”
Get full text

Factors Associated With the 30-day Readmission Rate in Patients With Heart Failure by Fereshteh Rezvani, Zahra Abbasi Dolatabadi, Maryam Esmaeili, Saman Maroufizadeh, Mohammad Garakyaraghi, Monir Mazaheri

“…Introduction: Heart failure (HF) is a complex and common clinical syndrome whose symptoms are caused by structural or functional disorders in the heart. Although several studies have been conducted to identify the factors associated with the hospital readmission of patients with HF, statistics still show a high readmission rate in these patients. …”
Get full text

Prospective associations of infant food exposures and appetitive traits with early childhood diet quality by Tonja R. Nansel, Amara Channell-Doig, Leah M. Lipsky, Kyle Burger, Grace Shearrer, Anna Maria Siega-Riz, Yong Ma

“…At child ages 3.5 and 5 years, parents provided two 24-h dietary recalls, from which the Healthy Eating Index-2020 was calculated to measure diet quality. Structural equation models using maximum likelihood estimation examined associations of age at introduction to, and intake frequency of, fruit/vegetables and discretionary foods, and their interactions with food-approach and food-avoidance appetitive traits, on child diet quality at ages 3.5 & 5 years, controlling for income, education, and breastfeeding duration. …”
Get full text

The development and implementation of an innovative community-based intervention to strengthen community capacity for HIV prevention and care among Canadians of African Caribbean a... by Josephine Etowa, Notisha Massaquoi, Francisca Omorodion, Danielle Brown-Shreves, Ilene Hyman, Akalewold Gebremeskel, Hugues Loemba, Bishwajit Ghose, Egbe Etowa, Jennifer Rayner, Charles Dabone, Lounanjio Brown O’Sullivan, Azeeza Sule, Joseph Kiirya, Sanni Yaya, Wangari Tharao, Haoua Inoua, Angela Kaida, Apondi Odhiambo, Clinton Beckford

“…African, Caribbean, and Black (ACB) women are overrepresented among new HIV diagnoses due to social and structural factors. This study seeks to create, implement, and evaluate a community-based peer-led intervention to improve access to HIV prevention and care for ACB women in Canada. …”
Get full text

A domain-based framework for cognitive profile identification in Parkinson’s disease across diverse samples by Elvira Andújar-Castillo, Carla Carrillo-Molina, Fernando Alonso, Fernando Alonso, Clara Villanueva-Iza, Clara Villanueva-Iza, Gustavo Fernández-Pajarín, Gustavo Fernández-Pajarín, Angel Sesar, Angel Sesar, Isabel Jiménez-Martín, Isabel Jiménez-Martín, Juan Francisco Martín-Rodriguez, Juan Francisco Martín-Rodriguez, Juan Francisco Martín-Rodriguez, Maria Jesús Lama, Pablo Mir, Pablo Mir, Pablo Mir, Elena Perez-Hernandez, Cristina Nombela Otero

“…This study provides empirical support for the implementation of domain-based cognitive assessments, structured in line with Movement Disorder Society recommendations, to provide a multidimensional evaluation of cognitive profiles in PD patients.MethodsNeuropsychological and clinical data were analyzed from 316 PD patients recruited from three Spanish hospitals—Hospital Clínico San Carlos (Madrid), the University Complejo Universitario de Santiago de Compostela (Galicia), and Hospital Virgen del Rocío (Sevilla)— and a control group of 96 older individuals, whose age difference from the PD group was statistically significant. …”
Get full text

The mediating role of biological age in the association between dietary index for gut microbiota and sarcopenia by Jingyuan Zhang, Jun Guo, Jing Zhang, Jing Zhang, Heng Liu, Lin Zhou, Chi Cheng, Hong Cao

“…Alterations in muscle structure are closely linked to DNA methylation-based biological age assessments and individual dietary patterns. …”
Get full text

Impact of different genomic relationship matrix construction methods on the accuracy of genomic prediction in different species by Shiyi Wang, Yingjia Wei, Dengying Liu, Xiangzhe Zhang, Qishan Wang, Yuchun Pan, Peipei Ma

“…The learning curve for bull data showed the choice of G-matrix had minimal impact on prediction accuracy when the reference population size and genetic marker density reached a certain threshold.DiscussionThe study concluded that the optimal G-matrix construction method varies across species, with population structure being a key factor. …”
Get full text

SURGERY OF BRAIN STEM CAVERNOUSES MALFORMATION by V. V. Stupak, Sh. Aul, A. G. Bobylev, M. V. Kutsenko, D. A. Dentsel, T. M. Shogunbekov, V. M. Bon, A. M. Gazeev, A. E. Simonovich, S. V. Tsvetovskiy

“…Cavernous malformations (CM), also known as cavernous angiomas or cavernomas, are benign vascular hamartomas having a sinusoidal type of wall structure.CM occurs in the brain stem with a frequency of 9–35 % of cases. …”
Get full text

Distribution Characteristics of Nutrients and Eutrophication Assessment in Yueqing Bay by YAO Kaixue, YIN Rui, WANG Yang, CHEN Feng, LI Zhenhua

“…Based on the Marine environment monitoring data of Yueqing Bay in spring, summer, autumn and winter from 2018 to 2019, the spatial and temporal distribution characteristics of nutrient salts (dissolved inorganic nitrogen, DIN) and active phosphate (DIP) in the sea were analyzed, and the pollution degree, eutrophication degree and nutrient structure of the sea area were evaluated by single factor index method, eutrophication index method and potential eutrophication model. …”
Get full text

Conserved missense variant pathogenicity and correlated phenotypes across paralogous genes by Tobias Brünger, Alina Ivaniuk, Eduardo Pérez-Palma, Ludovica Montanucci, Stacey Cohen, Lacey Smith, Shridhar Parthasarathy, Ingo Helbig, Michael Nothnagel, Patrick May, Dennis Lal

“…Across ten genes encoding voltage-gated sodium channels and 22 expert-curated disorders, we identify cross-paralog correlated phenotypes based on 3D structure spatial position. For example, multiple established loss-of-function related disorders across SCN1A, SCN2A, SCN5A, and SCN8A show overlapping spatial variant clusters. …”
Get full text

Functional Analysis of <i>Penicillium expansum</i> Glucose Oxidase-Encoding Gene, <i>GOX2</i>, and Its Expression Responses to Multiple Environmental Factors by Yongcheng Yuan, Yutong Ru, Xiaohe Yuan, Shuqi Huang, Dan Yuan, Maorun Fu, Wenxiao Jiao

“…It is either an integrated membrane protein (such as a receptor or channel) that is directly anchored to the membrane through a transmembrane structure or a non-classical secreted protein that is secreted extracellularly. …”
Get full text

Some issues of local drinking water supply of the population during martial law (using the example of Ukrainian cities with a population of over 100 thousand people). Part 2 by Yu. F. Rudenko, N. A. Yurkova, O. V. Gural, V. Yu. Saprykin

“…Considering the high potential risks of damage from massive weapons to urban agglomerations with a high population density and infrastructure facilities within residential areas, reliable supply of drinking water to the social structure is one of the most important factors in the life support of the population. …”
Get full text