A comprehensive review on novel opportunities for Alzheimer therapy by targeting BIN1 by Trina Saha, Dipanjan Karati

“…Conclusion The most frequent BIN1 variants are found in non-coding regions immediately upstream of the gene, and it is thus likely that their impact is regulatory and not structural. The variants can influence the levels of BIN1 or splicing between isoforms, especially the distribution of isoforms. …”
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INNOVATIVE EXPERIMENTAL TESTING PROGRAM OF DIRECT SHEAR TEST IN SOIL MECHANICS by Zakaria OWUSU-YEBOAH, Mircea ANICULAES, Andreea Vasilica DASCALU, Iancu Bogdan TEODORU, Irina LUNGU

“…The research work aims at analyzing for the first time the data set obtained on cohesive soil samples following the publication of the Romanian Invention Patent RO 134239. …”
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Molecular Determinants for the Binding of the Highly Infectious SARS-CoV-2 Omicron (BA.1) Variant to the Human ACE2 Receptor by Majed S. Aljohani, Pawan Bhatta, Xiche Hu

“…Additionally, allosteric effects improve the contributions of non-mutated residues (notably A475, Y453, and F486) via structural realignment and novel hydrogen bonding with ACE2 residues such as S19, leading to an overall increase in the electrostatic and π-system interaction energy. …”
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Diversity and equity in medical education over the past decade: applications, matriculations, and the growing gaps by Gang Lv, Xiangxiang Jiang, Jordan Franklin, Minghui Li, Jing Yuan, Z. Kevin Lu

“…Methods This study used data from the Association of American Medical Colleges from 2015 to 2024. …”
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Unveiling the ultimate advantage: a meta-analysis of 3D visualization and problem-based learning in orthopedic education by Ting Li, Yidan Hu, Ruohong Song, Hangyu Liu, Xin Gao, Fei Wang, Chengwei Xiao, Xilin Liu

“…Furthermore, students exposed to 3D + PBL teaching exhibited a significantly better understanding of orthopedic anatomical structures compared to those receiving LBL (SMD = 1.18, 95% CI: 0.71–1.65, P < 0.00001). …”
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Association of workplace support for health with occupational health literacy and illness avoidance: moderated mediation by functioning through a salutogenic lens by Nestor Asiamah, Isaac Aidoo, Etornam Doamekpor, Emelia Sarpong, Emelia Danquah, Cosmos Yarfi, Eric Eku, Usman Yaw Baidoo, Christiana Afriyie Manu, Rita Sarkodie Baffoe

“…., WSH, OHL, functioning, and illness avoidance) were measured with Likert-type scales adopted in whole from the literature. Data were analysed with Hayes’ Process Model through structural equation modelling. …”
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PSYCHOLOGICAL READINESS OF SECONDARY VOCATIONAL EDUCATION TEACHERS FOR MASTERING NEW ACTIVITIES IN THE CONTEXT OF PROFESSIONAL REORIENTATION by I. I. Khasanova, S. S. Kotova

“…The functionality of this technology, its tasks, structural components, possible methods and estimated effects of its implementation in practice of the SPE (Secondary Professional Education) system are noted.Practical significance. …”
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Simulation of the turbulent air flow of inhalation and exhalation in the respiratory system using computational fluid dynamics by Dheyaa J. Jasim, Mustafa Habeeb Chyad, Laith S. Sabri, Soheil Salahshour, Omid Ali Akbari, M. Hekmatifar

“…Limited research was conducted in the field of respiratory systems to examine the respiratory system as a true model for various input structures in inhalation and exhalation, although numerous studies were conducted by researchers. …”
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Enhancing Accessibility in Philippine Public Bus Systems: Addressing the Needs of Persons with Disabilities by Ma. Janice J. Gumasing, Timothy Ray P. Del Castillo, Antoine Gabriel L. Palermo, Janred Thien G. Tabino, Josiah T. Gatchalian

“…Structural equation modeling (SEM) was used to analyze the hypothesized relationships between these variables, passenger satisfaction, and intention to reuse public transport. …”
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Viral activity in lake analogs of anoxic early Earth oceans by Natascha S. Varona, Bailey A. Wallace, Alice Bosco-Santos, Julianna Mullinax, Alexandra K. Stiffler, Molly D. O’Beirne, Josh Ford, James M. Fulton, Josef P. Werne, William P. Gilhooly, Cynthia B. Silveira

“…This suggests that viral lysis may contribute less to bacterial community structuring in these high-density microbial plates. …”
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COOPERATION BETWEEN THE MINISTRY OF NATIONAL EDUCATION AND LOCAL SELF-GOVERNMENT BODIES OF THE PERM PROVINCE DURING THE PERIOD “PREPARATORY WORK FOR THE COMPULSORY EDUCATION INTROD... by S. V. Golikova

“…The key value and importance of the document consisted in differentiation of powers: in contrast to the Ministry of National Education, the structures of territorial and municipal government bodies had greater freedom of action and were assigned a leading part to put the idea of a compulsory education (Vseobuch in the Russian language) into reality.Dynamics of statistical data on financial government aid to national education is analysed. …”
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A descriptive analysis of significant factors influencing the behavioral intention to adopt robot kiosks/service robots in service stores: Integrating the UTAUT and higher-order SE... by Dioseph Andre F. Anduyo, Ardvin Kester S. Ong, Maela Madel L. Cahigas, Ma. Janice J. Gumasing, Dhonn Q. Tomas

“…Utilizing the integrated Unified Theory of Acceptance and Use of Technology (UTAUT) model and SERVQUAL 5 dimensions higher-ordered structural equation modeling approach, the study found that tangibles (β: 0.807), empathy (β: 0.782), responsiveness (β: 0.765), assurance (β: 0.711), reliability (β: 0.646), and behavioral intention (β: 0.104) significantly affected customer satisfaction. …”
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The Chain Mediating Effect of Health Literacy and Self-Care Ability on the Relationship Between Dysmenorrhea Symptoms and Negative Emotions Among Chinese Female College Students by Luo Y, Liu D, Sun G, Lu Y, Fang M, Zhang Y, Xu C, Bai G, Chen C

“…Multiple linear regression analysis was conducted to analyze the effects of variables with statistically significant differences (P < 0.05) identified through one-way ANOVA, independent sample t-tests, and correlation analysis on psychological levels. Structural Equation Modeling (SEM) was used to explore mediating effects.Results: This study shows that dysmenorrhea symptoms, health literacy, self-care ability, and negative emotions are significantly correlated. …”
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Airway epithelial cell-specific deletion of EGFR modulates mucoinflammatory features of cystic fibrosis-like lung disease in mice by Ishita Choudhary, Kshitiz Paudel, Rahul Kumar, Amit Sharma, Sonika Patial, Yogesh Saini

“…The airway epithelial cell-specific EGFR-deficient wild-type (WT) mice did not exhibit any obvious structural and functional defects in the lungs. The deletion of EGFR in airway epithelial cells in Tg+ mice, however, resulted in increased recruitment of neutrophils and macrophages into the lung airspaces, which was accompanied by significantly increased bronchoalveolar lavage fluid (BALF) levels of inflammatory mediators, including KC, G-CSF, MIP-2, MIP-1α, TNF-α, and MIP-1β. …”
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Formation of Adaptive and Integrative Potential of Children with Mental Retardation in Artistic and Creative Activities by O. A. Denisova, T. V. Gudina, I. A. Bukina, O. L. Lekhanova, A. V. Selina

“…Zuckermann), etc. The obtained data were processed through a mathematical method of assessing the significance of differences using the Spearman’s rank correlation coefficient.Results and scientific novelty. …”
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The Neurogenic Effects of Pasak bumi (Eurycoma longifolia Jack) and Seluang Fish (Rasbora spp.) in Malnutrition-Induced Rat by Didik Dwi Sanyoto, Triawanti Triawanti, Meitria Syahadatina Noor, Dimas Ikhsan Airlangga

“…Abstract Early developmental malnutrition exerts adverse effects on the structural, neurochemical, and neurophysiological maturation of cerebral cells by disrupting the process of neurogenesis. …”
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Lower extremity functional performance tests and their measurement properties in athletes: a systematic review and narrative synthesis by Alison Rushton, Nicola R Heneghan, Lee Herrington, James Martin, Rosalyn Cooke, Andy Soundy

“…Reliability (n=14), measurement error (n=11), structural validity/internal consistency (n=2), criterion validity (n=11), construct validity (n=5) and responsiveness (n=1) were assessed. …”
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Carotid intima thickness and elasticity combined with MHR predicting the severity of coronary artery stenosis in patients with premature coronary artery disease by Chenjing Xu, Ming Wu, Xijun Zhang, Kaikai Shen, Yanyan Guo, Jianjun Yuan, Haohui Zhu

“…Abstract Background Carotid intima thickness (CIT) and hardness coefficient (HC) are sensitive indicators of structural and functional changes in the carotid arteries in the subclinical stage of atherosclerosis. …”
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The relationship between digital literacy and innovative behavior among Chinese medical students: the chain mediating roles of diversity experience and creative self-efficacy by Juan Wu, Qilin Zhang, Xiaomin Gan, Xuefang Liu, Jiuying Hu, Yalin Wang

“…SPSS 25.0 and AMOS 24.0 software were used, and the structural equation model was established to statistically analyze the data. …”
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Does a growth mindset curb anxiety among Chinese medical students? Validation based on propensity score matching by Xiao-Jing Yang, Yu-Tian Gan, Zi-Jiao Wang, Jian-Ye Wang, Xiao-Jian Duan, Xing Ma, Tao Sun, De-Pin Cao, Shu-E Zhang

“…Educators should foster the cultivation of growth mindset in medical students through multidimensional interventions involving cognitive scaffolding, behavioral reinforcement, and environmental structuring, which consequently enhances their psychological well-being. …”
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