Prevalence and costs of headaches for the public health system in a town in the interior of the state of São Paulo Prevalência e custos das cefaléias para o Sistema Público de Saúd... by Marcelo E. Bigal, Janaína O.M. Bigal, Carlos A. Bordini, José G. Speciali

“…The aim of the present study was to estimate the prevalence of headaches in the public health system of a town in the interior of the State of São Paulo, as well as to estimate the costs resulting from its management. Data refer to the year of 1998 and were obtained according to the following steps: 1) territorial and demographic characterization of the municipality; 2) characterization of the financial indices and social well-being; 3) budget characteristics of the municipality; 4) evaluation of the structuring of the medical service; 5) determination of the prevalence of headaches at different patient care levels; and 6) calculation of the costs of headaches. …”
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Viral activity in lake analogs of anoxic early Earth oceans by Natascha S. Varona, Bailey A. Wallace, Alice Bosco-Santos, Julianna Mullinax, Alexandra K. Stiffler, Molly D. O’Beirne, Josh Ford, James M. Fulton, Josef P. Werne, William P. Gilhooly, Cynthia B. Silveira

“…This suggests that viral lysis may contribute less to bacterial community structuring in these high-density microbial plates. …”
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Does a growth mindset curb anxiety among Chinese medical students? Validation based on propensity score matching by Xiao-Jing Yang, Yu-Tian Gan, Zi-Jiao Wang, Jian-Ye Wang, Xiao-Jian Duan, Xing Ma, Tao Sun, De-Pin Cao, Shu-E Zhang

“…Educators should foster the cultivation of growth mindset in medical students through multidimensional interventions involving cognitive scaffolding, behavioral reinforcement, and environmental structuring, which consequently enhances their psychological well-being. …”
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Study on the Influence of Window Size on the Thermal Comfort of Traditional One-Seal Dwellings (Yikeyin) in Kunming Under Natural Wind by Yaoning Yang, Junfeng Yin, Jixiang Cai, Xinping Wang, Juncheng Zeng

“…Key findings include, (1) in summer, the baseline scenario with WWR = 0.1 achieves a dynamic thermal-humidity balance (20.89–24.27 °C, 65.35–74.22%) through a “air-permeable but non-ventilative” strategy, though wing rooms show humidity-heat accumulation risks; increasing WWR to 0.15–0.2 enhances ventilation efficiency (2–3 times higher air changes) but causes a 4.5% humidity surge; (2) winter conditions with WWR ≥ 0.15 reduce wing room temperatures to 17.32 °C, approaching cold thresholds, while WWR = 0.05 mitigates heat loss but exacerbates humidity accumulation; (3) a symmetrical layout structurally constrains central ventilation, maintaining main halls air changes below one Air Change per Hour (ACH). …”
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Deep sphingolipidomic and metabolomic analyses of ceramide synthase 2 null mice reveal complex pathway-specific effects by Jeongah Oh, Sneha Muralidharan, Qing Zhao, Johannes Scholz, Iris D. Zelnik, Shani Blumenreich, Tammar Joseph, Tamir Dingjan, Pradeep Narayanaswamy, Hyungwon Choi, Heiko Hayen, Federico Torta, Anthony H. Futerman

“…The sphingolipidome contains thousands of structurally distinct sphingolipid (SL) species. This enormous diversity is generated by the combination of different long-chain bases (LCBs), N-acyl chains and head groups. …”
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Empowering knowledge graphs with hybrid retrieval-augmented generation for the intelligent mix scheme of mass concrete by Yuqing Shang, Zhijiang Ke, Peng Lin, Qianhui Ren, Wenshan Zhang, Xiongwu Wang, Xiaotao Li, Fuyuan Gong, Shiqi Wang, Baofa Wang, Zhengkui Xu, Minglun Sun, Shunli Tan

“…Firstly, a total of 1723 mix proportioning records collected from 15 hydropower stations were structurally extracted using a customized data transformation tool. …”
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Espiritualidade como recurso terapêutico no ambulatório de cardiologia [Spirituality as a therapeutic resource in the cardiology outpatient clinic] [La espiritualidad como recurso... by Janaína Mengal Gomes Fabri, Eliane Ramos Pereira, Celia Caldeira Fonseca Kestenberg, Rose Mary Costa Rosa Andrade Silva, Isadora Pinto Flores, Angelica Yolanda Bueno Bejarano Vale de Medeiros

“…The study was approved by the research ethics committee. Results: the data were organized into two categories: “If God exists, why did he do this to me?” …”
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The Application of a Joint Distribution of Significant Wave Heights and Peak Wave Periods in the Northwestern South China Sea by Gongpeng Liu, Qunan Ouyang, Zhanyuan He, Na Zhang

“…This wave model has been extensively validated against field data and was run from 1979 to 2020 to generate long enough one-hourly <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mrow><mi>H</mi></mrow><mrow><mi>s</mi></mrow></msub></mrow></semantics></math></inline-formula> and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mrow><mi>T</mi></mrow><mrow><mi>p</mi></mrow></msub></mrow></semantics></math></inline-formula>. …”
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Development of Women Resilience in the Workplace: A Solution to Break the Glass Ceiling by Farajallah Rahimi, Maral Ahmadi Arpanahi

“…MethodologyThis research is applied in terms of purpose and based on the method of data collection in the category of descriptive-correlational research. …”
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Normalization of tumor vasculature by imiquimod: proposal for a new anticancer therapeutic indication for a TLR7 agonist by Jarosz-Biej Magdalena, Czapla Justyna, Ciepła Joanna, Smolarczyk Ryszard, Drzyzga Alina, Sprus-Lipka Dorota, Pilny Ewelina, Matuszczak Sybilla, Cichoń Tomasz

“…Imiquimod normalized tumor vasculature both structurally (by reducing vessel tortuosity and increasing pericyte coverage) and functionally (by improving tumor perfusion) in a dose-dependent manner. …”
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The Use of Neural Networks in Distance Education Technologies for the Identification of Students by O. A. Kozlova, A. A. Protasova

“…Methods of reviewing scientific literature on the research topic, methods of collecting, structuring and analyzing the information obtained were used as materials and methods.Research results. …”
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Practical Approaches to Patient-Centered Care in Europe: Mixed Methods Study Developing a Conceptual Framework for Comprehensive Cancer Care Networks by Emily Hickmann, Peggy Richter, Hannes Schlieter, Maja Cemazar, Dorota Dudek-Godeau, Nele Grapentin, Ellen Griesshammer, Marjetka Jelenc, Sigita Liutkauskiene, Alain Ravaud, Xavier Troussard, Simone Wesselmann

“…In this context, comprehensive cancer care networks (CCCNs) provide a new means of structuring and delivering quality cancer care, recognizing each patient’s unique preferences and needs. …”
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THE CONTENT OF FOREIGN LANGUAGE TRAINING FOR NON-LINGUISTIC STUDENTS IN HIGHER EDUCATION IN THE CONTEXT OF CONTEMPORARY CHALLENGES by Nataliia Bespalova, Neliia Blynova, Svitlana Medynska, Anna Voloboieva

“…Instruction is supported by a structurally logical sequence of disciplines, ensuring continuity with the content acquired in previously studied courses.…”
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The Ethical Significance of Brain-Computer Interfaces as Enablers of Communication by Toma Gruica

“…Ethical evaluation must therefore balance the immediate benefits of temporary communicative access against the structural vulnerabilities introduced by uncertain long-term provision. …”
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Development and Application of a Senolytic Predictor for Discovery of Novel Senolytic Compounds and Herbs by Jinjun Li, Kai Zhao, Guotai Yang, Haohao Lv, Renxin Zhang, Shuhan Li, Zhiyuan Chen, Min Xu, Naixue Yang, Shaoxing Dai

“…In the DrugBank database, 98 structurally novel candidate compounds with potential senolytic activity were identified. …”
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Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-Viral hsa-miR-132 Processing in CEM-SS Cells by Verena Schlösser, Helen Louise Lightfoot, Christine Leemann, Seyedeh Elnaz Banijamali, Aathma Merin Bejoy, Shashank Tiwari, Jeffrey L. Schloßhauer, Valentina Vongrad, Andreas Brunschweiger, Jonathan Hall, Karin J. Metzner, Jochen Imig

“…Results: We established that Enoxacin, but not the structurally similar compound nalidixic acid, exhibits strong anti-HIV-1 effects in the T-cell line CEM-SS, but not MT-4. …”
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Piloting the options assessment toolkit with national malaria programme leaders from the Asia–Pacific countries: a meeting report by Manash Shrestha, Sanjaya Acharya, Josselyn Neukom, Karma Lhazeen, Ngo Duc Thang, Muhammad Naeem Habib, Lyndes Wini, Tobgyel Tobgyel, Kesang Wangchuk, Huy Rekol, Lek Dysoley, Siv Sovannaroth, Minerva Simatuopang, Helen Dewi Prameswari, Asik Surya, Zau Ring, Mohammad Qasim Khan, Boualam Khamlome, Mohd Hafizi Abdul Hamid, Ram Kumar Mahato, Top Thapa, Sheen Angelou Juangco, Hee Il Lee, Hyun Il Shin, Kumudu Gunasekera, Champa Aluthwera, Prayuth Sudathip, Rungrawee Timpontree, Hoang Dinh Canh, Sonia Cheung, Muhammad Zeeshan Haroon, Shreehari Acharya, Robert J. Commons, Bipin Adhikari, Varunika Ruwanpura, Phone Si Hein, Abhijit Sharma, Poe Poe Aung, Neena Valecha, Kamala Thriemer, Caroline A. Lynch

“…Thematic analysis of qualitative data revealed that NMPs found the OAT useful and timely for structuring malaria policy discussions. …”
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Engagement of Indigenous peoples in commercial tobacco reform strategies: a scoping review protocol by Andrew Waa, Raglan Maddox, El-Shadan Tautolo, Michelle Kennedy, Patricia Nez Henderson, Hershel Clark, Priscilla Nez, Penney Upton, Andrew Daniel Perusco, Sydney A. Martinez, Sierra Wilcox, Jeyasakthi Venugopal

“…This review supports the global goal of eradicating commercial tobacco-related harms – reframing commercial tobacco use as a structurally imposed harm sustained by colonial and commercial forces rather than personal choice. …”
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The antioxidant property of CAPE depends on TRPV1 channel activation in microvascular endothelial cells by Miltha Hidalgo, Bárbara Railef, Vania Rodríguez, Carolina Navarro, Vanessa Rubio, Jorge Meneses-Pacheco, Sandra Soto-Alarcón, Christine Kreindl, Carolina Añazco, Leandro Zuñiga, Omar Porras

“…Herein, we hypothesized that a subfamily of TRP ion channels works as the molecular entity that recognizes CAPE at the plasma membrane and allows a fast shift in the antioxidant capacity of intact endothelial cells (EC).By monitoring cytoplasmic Ca2+ in a microvascular EC model, we compared the calcium responses evoked by three structurally related compounds: caffeic acid phenethyl ester, neochlorogenic acid and caffeic acid. …”
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Newly diagnosed diseases and the frequency of their occurrence in patients after a new coronavirus infection. Results of an International Register "Dynamics Analysis of Comorbiditi... by G. P. Arutyunov, E. I. Tarlovskaya, A. G. Arutyunov, D. S. Polyakov, Yu. N. Belenkov, A. O. Konradi, Yu. M. Lopatin, A. P. Rebrov, S. N. Tereshchenko, A. I. Chesnikova, H. G. Hayrapetyan, A. P. Babin, I. G. Bakulin, N. V. Bakulina, L. A. Balykova, A. S. Blagonravova, M. V. Boldina, M. I. Butomo, A. R. Vaisberg, A. S. Galyavich, V. V. Gomonova, N. Yu. Grigoryeva, I. V. Gubareva, I. V. Demko, A. V. Evzerikhina, A. V. Zharkov, A. A. Zateishchikova, U. K. Kamilova, Z. F. Kim, T. Yu. Kuznetsova, A. N. Kulikov, N. V. Lareva, E. V. Makarova, S. V. Malchikova, S. V. Nedogoda, M. M. Petrova, I. G. Pochinka, K. V. Protasov, D. N. Protsenko, D. Yu. Ruzanov, S. A. Saiganov, A. Sh. Sarybaev, N. M. Selezneva, A. B. Sugraliev, I. V. Fomin, O. V. Khlynova, O. Yu. Chizhova, I. I. Shaposhnik, D. A. Schukarev, A. K. Abdrakhmanova, S. A. Avetisyan, H. G. Avoyan, K. K. Azaryan, G. T. Aimakhanova, D. A. Ayypova, A. Ch. Akunov, M. K. Alieva, A. R. Almukhambedova, O. Yu. Aparkina, O. R. Aruslanova, E. Yu. Ashina, O. Yu. Badina, O. Yu. Barysheva, T. I. Batluk, A. S. Batchaeva, R. A. Bashkinov, A. M. Bitieva, I. U. Bikhteev, N. A. Borodulina, M. V. Bragin, V. A. Brazhnik, A. M. Budu, G. A. Bykova, K. R. Vagapova, D. D. Varlamova, N. N. Vezikova, E. A. Verbitskaya, O. E. Vilkova, E. .A. Vinnikova, V. V. Vustina, E. A. Elena A. Galova, V. V. Genkel, D. B. Giller, E. D. Gordeychuk, E. I. Gorshenina, E. V. Grigoryeva, E. Yu. Gubareva, G. M. Dabylova, A. I. Demchenko, O. Yu. Dolgikh, M. Y. Duishobaev, D. S. Evdokimov, K. E. Egorova48, A. E. Zheldybaeva, N. V. Zarechnova, Yu. D. Zimina, S. Yu. Ivanova, E. Yu. Ivanchenko, M. V. Ilina, M. V. Kazakovtseva, E. V. Kazymova, Yu. S. Yuliya S. Kalinina, N. A. Kamardina, A. M. Karachenova, I. A. Karetnikov, N. A. Karoli, M. Kh. Karsiev, D. S. Kaskaeva, K. F. Kasymova, Zh. B. Kerimbekova, E. S. Kim, N. V. Kiseleva, D. A. Klimenko, O. V. Kovalishena, S. V. Kozlov, E. V. Kolmakova, T. P. Kolchinskaya, M. I. Kolyadich, O. V. Kondryakova, M. P. Konoval, D. Yu. Konstantinov, E. A. Konstantinova, V. A. Kordyukova, E. V. Koroleva, A. Yu. Kraposhina, T. V. Kryukova, A. S. Kuznetsova, T. Yu. Kuzmina, K. V. Kuzmichev, C. K. Kulchoroeva, T. V. Kuprina, I. M. Kuranova, L. V. Kurenkova, N. Yu. Kurchugina, N. A. Kushubakova, V. I. Levankova, A. A. Ledyaeva, T. V. Lisun, V. E. Lisyanskaya, N. A. Lyubavina, N. A. Magdeeva, K. V. Mazalov, V. I. Mayseenko, A. S. Makarova, A. M. Maripov, N. V. Markov, A. A. Marusina, E. S. Melnikov, A. I. Metlinskaya, N. B. Moiseenko, F. N. Muradova, R. G. Muradyan, Sh. N. Musaelyan, E. S. Nekaeva, N. M. Nikitina, S. E. Nifontov, E. Yu. Obolentseva, A. A. Obukhova, B. B. Ogurlieva, A. A. Odegova, Yu. V. Yuliya V. Omarova, N. A. Omurzakova, Sh. O. Ospanova, V. A/ Pavlova, E. V. Pakhomova, L. D. Petrov, S. S. Plastinina, D. A. Platonov, V. A. Pogrebetskaya, D. V. Polyakov, E. V. Ponomarenko, L. L. Popova, A. A. Potanin, N. A. Prokofieva, Yu. D. Rabik, N. A. Rakov, A. N. Rakhimov, N. A. Rozanova, S. Serikbolkyzy, Ya. A. Sidorkina, A. A. Simonov, V. V. Skachkova, R. D. Skvortsova, D. S. Skuridin, D. V. Solovieva, I. A. Solovieva, I. M. Sukhomlinova, A. G. Sushilova, D. R. Tagaeva, E. P. Tikhonova, D. S. Tokmin, A. A. Tolmacheva, M. S. Torgunakova, K. V. Trenogina, N. A. Trostyanetskaya, D. A. Trofimov, M. A. Trubnikova, A. A. Tulichev, A. T. Tursunova, N. D. Ulanova, O. V. Fatenkov, O. V. Fedorishina, T. S. Fil, I. Yu. Fomina, I. S. Fominova, I. A. Frolova, S. M. Tsvinger, V. V. Tsoma, M. B. Cholponbaeva, T. I. Chudinovskikh, I. V. Shavrin, O. A. Shevchenko, D. R. Shikhaliev, E. A. Shishkina, K. Yu. Shishkov, S. Yu Shcherbakov, G. V. Shcherbakova, E. A. Yausheva

“…Demographic, clinical, and laboratory data, computed tomography (CT) results, information about inhospital clinical course and complications of COVID-19 during hospitalization were extracted from electronic health records using a standardized data collection form. …”
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