Deep learning-based carotid plaque vulnerability classification with multicentre contrast-enhanced ultrasound video: a comparative diagnostic study by Yanli Guo, Hongxia Zhang, Yang Guang, Wen He, Bin Ning, Chen Yin, Mingchang Zhao, Fang Nie, Pintong Huang, Rui-Fang Zhang, Qiang Yong, Jianjun Yuan, Yicheng Wang, Lijun Yuan, Litao Ruan, Tengfei Yu, Haiman Song, Yukang Zhang

“…Moreover, with a more powerful network structure and better utilisation of video information, DL-DCCP provided greater diagnostic accuracy than a state-of-the-art static CNN model.Trial registration number ChiCTR1900021846,…”
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A Multifaceted Computational Approach to Identify PAD4 Inhibitors for the Treatment of Rheumatoid Arthritis (RA) by Mansour S. Alturki, Mohamed S. Gomaa, Nada Tawfeeq, Abdulaziz H. Al Khzem, Mohsina B. Shaik, Murtadha Alshaikh Jafar, Mohammad Alsamen, Hasan Al Nahab, Mohammad Al-Eid, Alhassan Almutawah, Thankhoe A. Rants’o, Khaled A. G. Ayil, Mohammed Almaghrabi

“…Methods: We utilized Maestro Schrödinger as a computational tool for preparing and docking simulations on the PAD 4 enzyme crystal structure that is retrieved from RCSB Protein Data Bank (PDB ID: 4X8G) while the docked FDA-approved medications are obtained from the Zinc 15 database. …”
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Bidirectional associations among positive affect, anhedonia and meaning in life during major depressive episode: ecological momentary assessment study in unipolar and bipolar indiv... by Heidi Ka Ying Lo, Roger S. McIntyre, Iris Wai Tung Tsui, Fiona Yan Yee Ho, Ting Kin Ng, Corine Sau Man Wong, Suet Ying Yuen, Chit Tat Lee, Chun Yin Poon, Inez Myin-Germeys, Ka Fai Chung

“…Multilevel modelling analysis was conducted, with estimation of first-order autoregressive model structure and time-lagged relationship between pleasure and positive affect. …”
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Application of HRCT-based radiomics to predict interstitial lung disease for juvenile dermatomyositis by Lingke Liu, Minfei Hu, Yun Zhou, Fei Zheng, Xiaohui Ma, Li Yang, Yiping Xu, Liping Teng, Bin Hu, Meiping Lu, Xuefeng Xu

“…The lung intelligence kit (LK) software was used to outline the bilateral lung tissue structure automatically. The radiomics score combining with clinical variables was used to establish a prediction model for JDM-ILD. …”
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The effects of formula milk on development, nutrient absorption, and immune characteristics of piglets by Chuang Tang, Zhengjiang Liu, Lu Lu, Bo Zeng, Zhi Li, Ruohan Yang, Duoduo Zhang, Xiaolan Fan, Jiaxue Cao, Haohuan Li, Jing Sun, Jinwei Zhang, Xiaoyuan Wei, Wei Sun, Liangpeng Ge, Mingzhou Li, Fanli Kong

“…Given the ethical constraints in conducting experimental studies on human breastfeeding, we employed pig, which have similar physiological structure with humans, to examine the impacts of different feeding practices. …”
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The impact of nuchal ligament ossification resection on cervical stability after modified laminoplasty: a long-term follow-up study by Chong Chen, Wenlin Ye, Tao Yu, Xing Cheng, Lutong Wang, Xingchen Zhao, Xiang Long, Jun Ouyang, Yunbing Chang, Xiaoqing Zheng

“…For DCM patients with long segmental ONL, more attention should be paid to protecting the MLC structure during posterior cervical surgery. Clinical trial number Not applicable.…”
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Genetic assessment of Saccharina germplasm using SNP markers: Facilitating core collection establishment and fingerprinting identification by Zihan Gai, Shuxiu Chen, Shan Sai, Liping Liu, Yuting Zhai, Rui Qian, Ruina Wu, Juping Zhao, Liqin Wang, Yan Li, Yanling Liu, Weiwei Wang, Xiaojie Li, Linan Zhang

“…Accordingly, we established a core collection of 91 accessions that encompasses all SNP variations and retains the similar clustering structure as the initial collection. Additionally, we identified a set of 130 core SNP markers, which were successfully used for fingerprinting analysis and individual differentiation of the 91 accessions. …”
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Two Distinctly Different Characteristics of Flare-driven Coronal Rain Revealed from High-resolution Spectroscopic Imaging Observations with FISS/GST by Donguk Song, Eun-Kyung Lim, Jongchul Chae, Maria S. Madjarska, Masahito Kubo, Hannah Kwak, Juhyung Kang, Ryohtaroh T. Ishikawa, Kyoung-Sun Lee

“…We estimate the spatial scale of the fine structure of the coronal rain and the footpoint brightening. …”
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Characteristics of atmospheric variables over the southern coast of West Java in the presence of Australian Monsoon and MRG waves by Didi Satiadi, Trismidianto, Anis Purwaningsih, Dita Fatria Andarini, Risyanto, Teguh Harjana, Ibnu Fathrio, Alfan Sukmana Praja, Noersomadi, Fadli Nauval, Elfira Saufina, Ina Juaeni, Adi Witono, Aisya Nafiisyanti, Wendi Harjupa, Eddy Hermawan, Robi Muharsyah, Danang Eko Nuryanto

“…Moreover, we found the reduction of low-level pressure, the enhancement of temperature and relative humidity in the mid-troposphere, and the weakening of the easterly and southerly winds during the dry phase approaching the wet phase of the MRG waves over the southern coast of West Java following the wave structure and propagation.…”
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Petrology and mineral chemistry of the Hamaneh granitoid, West of Yazd (Central Iran zone) by Javad Ghanei Ardakani, Maryam Ahankoub

“…The parent magma of the rocks under study belongs to the subduction structural ground position related to the active continental margin.…”
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HyperCell: A Bio-inspired Design Framework for Real-time Interactive Architectures by Jia-Rey Chang

“…A holistic bio-inspired architecture embodies multiple performance criteria akin to natural systems, which integrate structural, infrastructure performances throughout the growth of an organic body. …”
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Correlates of duration between initial drug use and first drug injection among people who inject drugs in Iran, 2020 by Zahra Abdolahinia, Zahra Jaafari, Ali Karamoozian, Soheil Mehmandoost, Nima Ghalekhani, Mehrdad Khezri, Ghazal Mousavian, Mostafa Shokoohi, Ali Mirzazadeh, Ali Akbar Haghdoost, Mohammad Karamouzian, Mohammad Mehdi Gooya, Samaneh Akbarpour, Hamid Sharifi, Fatemeh Tavakoli

“…Policymakers should prioritize evidence-based, multi-faceted approaches that target both individual and structural factors to delay or prevent the transition to injection drug use and reduce associated health risks.…”
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TSHD: Topic Segmentation Based on Headings Detection (Case Study: Resumes) by Majd E. Tannous, Wassim H. Ramadan, Mohanad A. Rajab

“…Many unstructured documents contain segments with specific topics. …”
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Integrated assessment of antimicrobial stewardship in carbapenem resistant Klebsiella pneumoniae prevalent hospitals in China: a multidisciplinary surveillance network-based survey by Haishaerjiang Wushouer, Weibin Li, Junxuan Yu, Lin Hu, Xiaodong Guan, Xiaolin Liu, Anhua Wu, Xiaoqiang Yang, Minggui Wang, Yingchun Xu, Yanping Luo, Xun Huang, Luwen Shi

“…Five key areas were identified for improving multidisciplinary AMS: organizational structure, staffing and training, drug formulary and prescription management, laboratory testing and quality control, and clinical sampling and data reporting. …”
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Multifractal Analysis and Experimental Evaluation of MCM-48 Mesoporous Silica as a Drug Delivery System for Metformin Hydrochloride by Mousa Sha’at, Maria Ignat, Liviu Sacarescu, Adrian Florin Spac, Alexandra Barsan (Bujor), Vlad Ghizdovat, Emanuel Nazaretian, Catalin Dumitras, Maricel Agop, Cristina Marcela Rusu, Lacramioara Ochiuz

“…<b>Results</b>: SEM-EDX confirmed the uniform distribution of silicon and oxygen, while TEM images revealed a highly ordered cubic mesoporous structure. Nitrogen adsorption analyses showed a high specific surface area of 1325.96 m²/g for unloaded MCM-48, which decreased with drug loading, confirming efficient incorporation of metformin hydrochloride. …”
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Global variation in antibiotic prescribing guidelines and the implications for decreasing AMR in the future by Emmama Jamil, Emmama Jamil, Zikria Saleem, Brian Godman, Brian Godman, Brian Godman, Matti Ullah, Afreenish Amir, Abdul Haseeb, Johanna C. Meyer, Johanna C. Meyer, Muhammad Usman Qamar, Safa S. Almarzoky Abuhussain

“…The findings highlighted significant disparities in the development, adaptation, and implementation of guidelines across different WHO regions, confirming the previously noted lack of standardization and comprehensiveness in LMICs.ConclusionSignificant disparities exist in the availability, structure, and methodological rigor of antibiotic prescribing guidelines across countries with different income levels. …”
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New Epitopes for the Serodiagnosis of Human Borreliosis by Mônica E. T. Alcón-Chino, Virgínia L. N. Bonoldi, Rosa M. R. Pereira, Gilberto S. Gazeta, João P. R. S. Carvalho, Paloma Napoleão-Pêgo, Andressa M. Durans, André L. A. Souza, Salvatore G. De-Simone

“…Cross-reactivity was assessed through data bank access and in vitro analysis. Among the 19 epitopes identified, four were selected for further investigation based on their signal intensity, secondary structure, and peptide matching. …”
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Dalbavancin to facilitate early discharge in the treatment of complex musculoskeletal infections: a multi-centre real-life application by T. Azamgarhi, S. Warren, A. Scobie, N. Karunaharan, C. Perez-Sanchez, R. Houghton, S. Hassan, J. Lourtet-Hascoët, J. Lourtet-Hascoët, H. Kershaw, P. Sendi, K. Saeed, K. Saeed

“…Although dalbavancin is approved for acute bacterial skin and skin structure infections, its off-label use in complex musculoskeletal infection (MSKI) is increasing. …”
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Genome-wide identification of the regulatory network of mitogen-activated protein kinase signaling cascades gene families in Hevea Brasiliensis by Xiaojuan Huang, Manman Sun, Xiaoyu Du, Lin Quan, Jinquan Chao, Xiaomin Deng, Hongze Liao

“…Conserved motifs, gene structure, and motif analysis further bolster the validity of phylogenetic classification. …”
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Efficacy of psychosocial interventions on social functioning in individuals with childhood maltreatment experiences: a protocol for a systematic review and network meta-analysis by Natalia E. Fares-Otero, Silvia Amoretti, Brisa Solé, Sarah L. Halligan, Eduard Vieta, Stefan Leucht, Soraya Seedat, Mathias Harrer

“…Other candidate moderators/mediators (personality, post-traumatic symptoms, brain structure/function, cognitive reserve) will also be explored and narratively summarised. …”
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