Urban pertussis epidemiological patterns in a highly vaccinated megacity: Policy impacts and control strategies in Chongqing, China, 2005-2024 by Rui Shen, Jiawei Xu, Yugang Li, Jianxing Yu, Na Sun, Zilu Xu, Xueying Xu, Xiao Liu, Yang Liu, Bosong Li, Li Qi, Luzhao Feng

“…Methods: Using population-based surveillance data (2005-2024) from Chongqing (population 32.1 million; DTP3 coverage >97%), we conducted hierarchical Bayesian spatial modeling and age-structured Susceptible-Infected-Recovered-Vaccinated transmission analysis. …”
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Translating community-wide spectral library into actionable chemical knowledge: a proof of concept with monoterpene indole alkaloids by Sarah Szwarc, Adriano Rutz, Kyungha Lee, Yassine Mejri, Olivier Bonnet, Hazrina Hazni, Adrien Jagora, Rany B. Mbeng Obame, Jin Kyoung Noh, Elvis Otogo N’Nang, Stephenie C. Alaribe, Khalijah Awang, Guillaume Bernadat, Young Hae Choi, Vincent Courdavault, Michel Frederich, Thomas Gaslonde, Florian Huber, Toh-Seok Kam, Yun Yee Low, Erwan Poupon, Justin J. J. van der Hooft, Kyo Bin Kang, Pierre Le Pogam, Mehdi A. Beniddir

“…Additionally, our work enabled the digitization of structural data for diverse MIA skeletons by converting them into machine-readable formats and thereby enhancing their dissemination for the scientific community. …”
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Unraveling the Mysteries of KS 1947+300: Multiwavelength Observations in a Low-eccentricity Be/X-Ray Binary by Wei Liu, Pablo Reig, Jingzhi Yan, Peng Zhang, Xiukun Li, Bo Gao, Guangcheng Xiao, Zhongmu Li, Qingzhong Liu

“…The fact that the amplitude of variability increased with wavelength suggests that the long-term decrease in the optical emission is due to weakening of the circumstellar disk. Structural changes in the disk may also be the origin of the periodic signals with periods ∼200 days detected in the Zwicky Transient Facility (ZTF)- g and ZTF- r band light curves. …”
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Prospects for AI clinical summarization to reduce the burden of patient chart review by Chanseo Lee, Kimon A. Vogt, Sonu Kumar

“…Effective summarization of unstructured patient data in electronic health records (EHRs) is crucial for accurate diagnosis and efficient patient care, yet clinicians often struggle with information overload and time constraints. …”
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Experiences of pregnant women regarding the use of traditional medicine (isihlambezo) at King Cetshwayo District in KwaZulu-Natal by Siphiwe Themba Madlala, Mpilo Shange

“…Twelve participants who were purposefully selected to collect data were interviewed until data saturation was reached using unstructured interviews as data collecting strategy. …”
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Text classification to streamline online wildlife trade analyses. by Oliver C Stringham, Stephanie Moncayo, Katherine G W Hill, Adam Toomes, Lewis Mitchell, Joshua V Ross, Phillip Cassey

“…Further work to integrate other machine learning tools, such as image classification, may provide better predictive abilities in the context of streamlining data processing for wildlife trade related online data.…”
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The clinical spectrum associated with ERCC5 mutations: Is there a relationship between phenotype and genotype? by Jinpeng Zhang, Jiannan Ma, Yuanyuan Luo, Siqi Hong, Li Jiang, Tianyi Li

“…The gene mutation has not been reported and was predicted to seriously affect the protein structure. According to a review of 59 cases of ERCC5 mutations, cerebrooculofacioskeletal syndrome (COFS) occurred in 16 cases, XP in 19 cases, and XP/CS in 24 cases. …”
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Design of cross-reactive antigens with machine learning and high-throughput experimental evaluation by Chelsy Chesterman, Thomas Desautels, Luz-Jeannette Sierra, Kathryn T. Arrildt, Adam Zemla, Edmond Y. Lau, Shivshankar Sundaram, Jason Laliberte, Lynn Chen, Aaron Ruby, Mark Mednikov, Sylvie Bertholet, Dong Yu, Kate Luisi, Enrico Malito, Corey P. Mallett, Matthew J. Bottomley, Robert A. van den Berg, Daniel Faissol

“…The top mutant identified underwent biophysical and x-ray crystallographic characterization to confirm that the overall structure of fHbp was maintained throughout this epitope engineering experiment. …”
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Recognition and cleavage of human tRNA methyltransferase TRMT1 by the SARS-CoV-2 main protease by Angel D'Oliviera, Xuhang Dai, Saba Mottaghinia, Sophie Olson, Evan P Geissler, Lucie Etienne, Yingkai Zhang, Jeffrey S Mugridge

“…We also determined the structure of an Mpro-TRMT1 peptide complex that shows how TRMT1 engages the Mpro active site in an uncommon substrate binding conformation. …”
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Study on the incremental carbon sink of tea plantations under spatio-temporal variation characteristics by Yaxiang Pan, Yaxiang Pan, Jingling Bao, Jingling Bao, Yuxuan Ji, Yuxuan Ji, Wen Li, Wen Li, Weiyu Lin, Shuisheng Fan, Shuisheng Fan, Shuisheng Fan, Liyu Mao, Liyu Mao

“…The results show that: (1) During the period of 2010–2022, the total carbon sink of tea plantations in Fujian Province increased by 133.12 × 105Mg, showing a continuous growth trend; in terms of spatial distribution, the intensity of tea plantation carbon sinks in the study area showed a gradual and present trend of migration and concentration from the southwest to the northeast. (2) Construct the evaluation index system of carbon sinks in tea plantations, divided into social, living, industrial and population factors and other four categories of eight indicators. (3)The single-factor driver of tea plantation carbon sinks shows that it is mainly affected by industrial scale, population density and industrial structure, with q-values exceeding 0.5. (4)The interaction of the drivers shows that the urban-rural disparity and industrial scale have the highest interaction effect, with q-values reaching 0.9698. …”
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Atmospheric Boundary Layer Stability in Urban Beijing: Insights from Meteorological Tower and Doppler Wind Lidar by Linlin Wang, Bingcheng Wan, Yuanjian Yang, Sihui Fan, Yi Jing, Xueling Cheng, Zhiqiu Gao, Shiguang Miao, Han Zou

“…The limited understanding of the structure of the urban surface atmospheric boundary layer can be attributed to its inherent complexity, as well as a deficiency in comprehensive measurements. …”
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Changes in the intestinal microbiota induced by the postnatal environment and their association with hypertension by Patrizia Dardi, Camille Perella Coutinho, Sarah de Oliveira, Simone Aparecida Teixeira, Renaide Rodrigues Ferreira Gacek, Eduardo Purgatto, Marco Aurélio Ramirez Vinolo, Marcelo Nicolás Muscará, Luciana Venturini Rossoni

“…In this sense, the current study explored the influence of normotensive and hypertensive postnatal environments on the intestinal microbiota structure, composition, and functional capacity of SHR and Wistar rats. …”
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Clinical and epidemiological characteristics of imported intestinal infections in children by E. Yu. Pylaeva, N. N. Zverevа, А. А. Erovichenkov, S. K. Pylaeva, E. A. Artamonova, N. Yu. Pshenichnaya, A. M. Demkina, O. N. Solodovnikova, Yu. N. Khlypovka, A. Yu. Dyagileva, A. Kh. Nurpeysova, A. U. Berestovskaia, O. V. Shamsheva, D. N. Protsenko

“…Imported intestinal infections most often occurred with symptoms of gastroenteritis, were assessed by CDS at 5 points, and rotavirus predominated in the etiological structure.…”
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Comparative analysis of mitochondrial genomes in lycoperdaceae fungi reveals intron dynamics and phylogenetic relationships by Xianyi Wang, Guoyu Wang, Jiawei Tao, Zhongyao Guo, Guangyin Xu, Jiayu Li, Jichuan Kang, Qin Zuo, Hongmei Liu, Qirui Li

“…However, mitochondrial genome data for the Lycoperdaceae family is insufficient, and investigating its structure offers valuable insights into the evolutionary relationships between puffball fungi and other Agaricales taxa. …”
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Unveiling host-genetic drivers of caecal microbial communities in chickens through genome-wide association studies by Ankit Hinsu, Xiaoxia Dai, Christos Dadousis, Christos Dadousis, Melanie Hay, Bruno Fosso, Matteo Crotta, Ramesh Pandit, Javier Guitian, Fiona Tomley, Prakash Koringa, Chaitanya Joshi, Chaitanya Joshi, Damer Blake, Androniki Psifidi

“…Whole-genome sequencing data were then used to further investigate candidate regions around significantly associated variants from the high-density DNA array. …”
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A novel gene linked to Imipenem resistance in E. coli isolate lacking known Imipenem-resistance genes by Trang Thu Hoang, Huyen Thanh Thi Le, Sang Ngoc Nguyen, Ung Dinh Nguyen, Tuan Ngoc Tran, Cuong Hung Nguyen, Thang Quang Truong, Nam S. Vo, Duc Quang Le, Son Hoang Nguyen, Minh Duc Cao, Thi Minh Ngoc Dao, Thi Huyen Bui, Thu An Nguyen, Thi Lan Anh Pham, Thi Bich Thao Le, Tho Huu Ho

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Trait-mediated responses and co-occurrence patterns of breeding steppe birds under human footprint in Inner Mongolia by Wenyu Xu, Chunlu Wang, Yanqi Wang, Xi Yang, Lishi Zhang, Piotr Tryjanowski, Frédéric Jiguet, Zheng Han, Haitao Wang

“…This study investigates how human impacts affect the distribution and community structure of breeding steppe birds in Inner Mongolia, a biodiversity hotspot in Asia. …”
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Longitudinal Immunoprofiling of the CD8⁺ T-Cell Response in SARS-CoV-2 mRNA Vaccinees and COVID-19 Patients by Jesús Emanuel Brunetti, Beatriz Escudero-Pérez, Fátima Lasala, Gonzalo Rivas, Mikel Mancheño-Losa, David Rial-Crestelo, Jaime Lora-Tamayo, Dániel Cadar, Miles Carroll, Rafael Delgado, César Muñoz-Fontela, Estefanía Rodríguez

“…Of note, we have observed variations in the memory subset structure at every stage of disease and vaccination. …”
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Neural correlates of device-based sleep characteristics in adolescents by Qing Ma, Barbara J. Sahakian, Bei Zhang, Zeyu Li, Jin-Tai Yu, Fei Li, Jianfeng Feng, Wei Cheng

“…These biotypes also differ in cognitive performance and brain structure and function. Longitudinal analysis confirms these differences from ages 9 to 14, with biotype 3 showing consistent cognitive advantages. …”
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Diagnosis and activity prediction of SLE based on serum Raman spectroscopy combined with a two-branch Bayesian network by Qianxi Xu, Qianxi Xu, Qianxi Xu, Xue Wu, Xue Wu, Xue Wu, Xinya Chen, Ziyang Zhang, Jinrun Wang, Jinrun Wang, Zhengfang Li, Zhengfang Li, Zhengfang Li, Xiaomei Chen, Xiaomei Chen, Xiaomei Chen, Xin Lei, Xin Lei, Zhuoyu Li, Zhuoyu Li, Zhuoyu Li, Mengsi Ma, Mengsi Ma, Mengsi Ma, Chen Chen, Lijun Wu, Lijun Wu

“…DBayesNet is primarily composed of a two-branch structure, with features at different levels extracted by the Bayesian Convolution (BayConv) module, Attention module, and finally, feature fusion performed by Concate, which is performed by the Bayesian Linear Layer (BayLinear) output to obtain the result of the classification prediction.ResultsThe two sets of Raman spectral data were measured in the spectral wave number interval from 500 to 2000 cm-1. …”
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