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52301
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52302
Evaluation of drug release from topical dosage forms and permeability prediction through the skin barrier (review)
Published 2024-09-01“…An example of relationship of "structure-permeability" correlation are the equations relating the permeability constant and lipophilicity to the molecular weight of the drug. …”
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52303
Immunological cluster complexes in kidney transplantation
Published 2022-03-01“…The composition of the central point of clustering of the hyperergic immunological complex is represented by the cooperation of CD3+CD8+CD69+ and CD3+CD4+CD8+ cells. The structure of the tolerogenic immune response in patients after kidney transplantation is based on intercellular interactions, which has a hierarchical system, the basis of which is represented by the cooperation of regulatory cells CD3+CD4+CD25+highCD127+low, CD3+CD4-CD8-, CD3+CD4+CD69+, CD3+CD16+CD56+, CD19+CD5+, LIN-HLA-DR+CD11c-CD123+. …”
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52304
Volumetric 3D Reconstruction of Large Osteochondral Lesions of the Talus Being Reconstructed with Viable Osteochondral Allograft Combined with Autograft
Published 2025-03-01“…A stable bony base and viable cartilage rim was established, removing all damaged cartilage and nonstructural bone debris from the OLT. Talar body structure and morphology was restored using autograft iliac crest or tibial placed into the bony defect. …”
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52305
Association between short-term exposure to meteorological factors on hospital admissions for hemorrhagic stroke: an individual-level, case-crossover study in Ganzhou, China
Published 2025-02-01“…Within the cumulative lag day structure of the subcomponent layer, both extremely low and extremely high temperature had a more pronounced effect on females and aged ≥65 years. …”
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52306
Automatic MRI Lymph Node Annotation From CT Labels
Published 2025-01-01“…After annotating a medical imaging modality that is relatively straightforward to label, doctors often expect automatic annotations for images from other modalities of the same region, even though these modalities differ in contrast and structure. This study focuses on creating automatic lymph node annotation in MRI images using available CT annotations via deep-learning models. …”
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52307
One step reconstruction of carbon/P zeolite from coal gasification slag and its adsorption mechanism for crystal violet
Published 2025-05-01“…The composite material has a flower shaped multi-level pore structure with a specific surface area of 107 m2/g, mainly composed of mesopores. …”
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52308
Multi-Omics and Sensory Analysis of <i>Coffea canephora</i>: Assessing the Impact of Roasting Speed on Safety and Energy Efficiency
Published 2024-07-01“…Notably, their interaction was identified as a statistically significant discriminant factor (Residual Structure Ratio <i>p</i>-value = 0.01), with the highest contribution to the model (Relative Sum of Squares = 32.6%). …”
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52309
Synthesis and physical-chemical properties of 6-(5-(1Н-tetrazole-1-ylmethyl)-4-R-1,2,4-triazole-3-ylthio)pyridin-3-amines and 6-((5-(1Н-tetrazole-1-yl)methil-4-R-1,2,4-triazole-3-y...
Published 2017-02-01“…The computer prediction was performed using PASS online service, it was found that the synthesized 6-(5-(1Н-tetrazole-1-ylmethyl)-4-R-1,2,4-triazole-3-ylthio)pyridin-3-amines and 6-((5-(1Н-tetrazole-1-yl)methil-4-R-1,2,4-triazole-3-ylthio)pyridin-3-yl)-(alk,ar,heter)ylmethanimines are low-toxic compounds and exhibit a wide range of biological actions, which corresponds to literature data. Conclusions. The results of our work have confirmed the structure of the synthesized compounds, which indicates the possibility of their further use in biological studies.…”
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52310
Análisis de las metodologías de benchmarking genéricas y aplicables al deporte (Analysis of generic benchmarking methodologies applicable to sports)
Published 2024-03-01“…In this article, the objective is to analyze different methodologies related to benchmarking in a generic way and applied to sport, based on its importance, structure and applications. To the same extent, an analysis of the main methodologies and their adaptation to sport is shown. …”
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52311
Research on Key Technology for Perforating 10 000-Metre Deep-Earth Exploration Wells
Published 2024-08-01“…Firstly, the perforator pressure-bearing design, supporting pyrotechnic formula, liner formula and structure were improved and upgraded respectively, numerical simulation of perforator external pressure strength is carried out, and tests of perforator extreme pressure resistance and ground target shooting are carried out, which improved the temperature and pressure resistance index of perforator to 260℃/245MPa. …”
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52312
Benzbromarone Analog SAR: Potent hURAT1 (SLC22A12) Inhibitors and Drug Transporter Interaction Studies
Published 2025-02-01“…One, to report two benzbromarone analogs and test their in vitro activity in the URAT1 inhibition assay; and two, to probe the structure–activity relationship (SAR) of various benzbromarone analogs regarding other drug transporters that may play a role in the uric acid uptake/elimination interplay.Methods: In brief, chemical synthesis of two benzbromarone analogs was prepared using methods analogous to those reported. …”
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52313
A család ereje: A házasságban élés és a nagycsaládos lét kapcsolata a jóllét különböző mutatóival
Published 2025-06-01“… The Strength of the Family: Links between Marital Status, Large Family Structure, and Indicators of Well-Being. THEORETICAL BACKGROUND – Based on previous empirical findings, the relationship between family formation, the number of children, and subjective well-being cannot be considered unambiguous. …”
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52314
Negotiating Islamic Law through Custom: Resistance in Family Law Practices among the Anak Dalam Community in Jambi
Published 2025-06-01“…Challenging prevailing scholarly emphasis on integrative frameworks between Islamic law and local custom, this study demonstrates that, in the SAD context, resistance emerges when elements of Islamic jurisprudence (fiqh) clash with the community’s socio-cultural structure and shared values. Using a socio-legal approach and qualitative methods, the research draws on in-depth interviews with seven key informants, including a religious leader, the tumenggung (tribal chief), customary elder, community facilitator, subdistrict head, and SAD community members. …”
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52315
Explanation of Good Governance Factors in Shiraz
Published 2023-04-01“…But one of the differences that can be seen in this research with similar researches is the emphasis of this research on an important factor under the title of " institutional capacity of organization" in order to apply the concepts and criteria of good urban governance in the structure of local, regional and national governments. …”
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52316
Postpartum maternal bonding scale: Development and validation in a low- and middle- income country setting.
Published 2025-01-01“…After multiple rounds of expert review and cognitive pretesting, a 30-item tool was selected for field testing. Using data from 310 postpartum women, we examined the tool's structure through exploratory (EFA) and confirmatory factor analysis (CFA), leading to a refined 12-item tool. …”
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52317
Study on the Impact of Exclosures on the Physicochemical Properties of Rangeland Soil (Case Study: Northern Golestan Province, Sufikam Rangelands)
Published 2024-09-01“…Among the remedial methods for degraded soils, increasing rangeland fertility and striving to improve soil structure stability, reducing livestock trampling through grazing restrictions, are highlighted. …”
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52318
Improvement and Validation of System Code for Thermal-hydraulic Analysis of In-pool Passive Residual Heat Removal System
Published 2025-04-01“…This study can provide the basic technology support for the structure design of PRHRS and safety analysis of the reactor system. …”
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52319
Interrelations of physical state parameters and biological age of students in the process of physical education
Published 2024-02-01“…It was found that the key indicators of students' physical state (PS) structure, which exerted the most significant influence on BMI, differ between young men and women. …”
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52320
Psychological adaptation and quality of life of patients who underwent lower limb amputation due to cancer
Published 2022-04-01“…It was found that functional capability (p<0.01), objective (p<0.001) and subjective (p<0.001) severity of pain syndrome, as well as employment (p=0.05) have the lowest indicators in group 1 compared with group 2; at the same time, the levels of QoL in both groups of patients do not differ and do not correspond the expert assessment, exceeding it; patients rate their cognitive and emotional activity most highly; the lowest, physical and role activity, and financial impact. In the structure of coping of group 1, the strategy “Seeking for social support” predominates; the values of the scales “Distancing” (p=0.05), “Escape–avoidance” (0.1<p<0.05), “Positive reappraisal” (p<0.05) are higher than in group 2, but lower than average normative values. …”
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