Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD by Yingxue Mei, Fei She, Ling Zhang, Gamin Kim, Ruomeng Li, Xiuzhi Zheng, Zonghai Wang, Renxuan Chen, Long Wang, Dongmei Chen, Jungho Kim, Tao Zhang, Tae Ho Lee

“…Abstract Neuronal cell death is a causative process in traumatic brain injury (TBI)-induced structural and functional impairment of the central nervous system. …”
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UE-NER-2025: A GPT-Based Approach to Multi-Lingual Named Entity Recognition on Urdu and English by Muhammad Ahmad, Humaira Farid, Iqra Ameer, Fida Ullah, Muhammad Muzamil, Muhammad Jalal, Ameer Hamza, Ildar Batyrshin, Grigori Sidorov

“…Named Entity Recognition (NER) is a fundamental task that identifies and classifies entities into predefined categories from unstructured text. As textual data continues to grow and span diverse linguistic communities, NER is rarely studied as a multilingual task, particularly for low-resource languages. …”
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Newly diagnosed diseases and the frequency of their occurrence in patients after a new coronavirus infection. Results of an International Register "Dynamics Analysis of Comorbiditi... by G. P. Arutyunov, E. I. Tarlovskaya, A. G. Arutyunov, D. S. Polyakov, Yu. N. Belenkov, A. O. Konradi, Yu. M. Lopatin, A. P. Rebrov, S. N. Tereshchenko, A. I. Chesnikova, H. G. Hayrapetyan, A. P. Babin, I. G. Bakulin, N. V. Bakulina, L. A. Balykova, A. S. Blagonravova, M. V. Boldina, M. I. Butomo, A. R. Vaisberg, A. S. Galyavich, V. V. Gomonova, N. Yu. Grigoryeva, I. V. Gubareva, I. V. Demko, A. V. Evzerikhina, A. V. Zharkov, A. A. Zateishchikova, U. K. Kamilova, Z. F. Kim, T. Yu. Kuznetsova, A. N. Kulikov, N. V. Lareva, E. V. Makarova, S. V. Malchikova, S. V. Nedogoda, M. M. Petrova, I. G. Pochinka, K. V. Protasov, D. N. Protsenko, D. Yu. Ruzanov, S. A. Saiganov, A. Sh. Sarybaev, N. M. Selezneva, A. B. Sugraliev, I. V. Fomin, O. V. Khlynova, O. Yu. Chizhova, I. I. Shaposhnik, D. A. Schukarev, A. K. Abdrakhmanova, S. A. Avetisyan, H. G. Avoyan, K. K. Azaryan, G. T. Aimakhanova, D. A. Ayypova, A. Ch. Akunov, M. K. Alieva, A. R. Almukhambedova, O. Yu. Aparkina, O. R. Aruslanova, E. Yu. Ashina, O. Yu. Badina, O. Yu. Barysheva, T. I. Batluk, A. S. Batchaeva, R. A. Bashkinov, A. M. Bitieva, I. U. Bikhteev, N. A. Borodulina, M. V. Bragin, V. A. Brazhnik, A. M. Budu, G. A. Bykova, K. R. Vagapova, D. D. Varlamova, N. N. Vezikova, E. A. Verbitskaya, O. E. Vilkova, E. .A. Vinnikova, V. V. Vustina, E. A. Elena A. Galova, V. V. Genkel, D. B. Giller, E. D. Gordeychuk, E. I. Gorshenina, E. V. Grigoryeva, E. Yu. Gubareva, G. M. Dabylova, A. I. Demchenko, O. Yu. Dolgikh, M. Y. Duishobaev, D. S. Evdokimov, K. E. Egorova48, A. E. Zheldybaeva, N. V. Zarechnova, Yu. D. Zimina, S. Yu. Ivanova, E. Yu. Ivanchenko, M. V. Ilina, M. V. Kazakovtseva, E. V. Kazymova, Yu. S. Yuliya S. Kalinina, N. A. Kamardina, A. M. Karachenova, I. A. Karetnikov, N. A. Karoli, M. Kh. Karsiev, D. S. Kaskaeva, K. F. Kasymova, Zh. B. Kerimbekova, E. S. Kim, N. V. Kiseleva, D. A. Klimenko, O. V. Kovalishena, S. V. Kozlov, E. V. Kolmakova, T. P. Kolchinskaya, M. I. Kolyadich, O. V. Kondryakova, M. P. Konoval, D. Yu. Konstantinov, E. A. Konstantinova, V. A. Kordyukova, E. V. Koroleva, A. Yu. Kraposhina, T. V. Kryukova, A. S. Kuznetsova, T. Yu. Kuzmina, K. V. Kuzmichev, C. K. Kulchoroeva, T. V. Kuprina, I. M. Kuranova, L. V. Kurenkova, N. Yu. Kurchugina, N. A. Kushubakova, V. I. Levankova, A. A. Ledyaeva, T. V. Lisun, V. E. Lisyanskaya, N. A. Lyubavina, N. A. Magdeeva, K. V. Mazalov, V. I. Mayseenko, A. S. Makarova, A. M. Maripov, N. V. Markov, A. A. Marusina, E. S. Melnikov, A. I. Metlinskaya, N. B. Moiseenko, F. N. Muradova, R. G. Muradyan, Sh. N. Musaelyan, E. S. Nekaeva, N. M. Nikitina, S. E. Nifontov, E. Yu. Obolentseva, A. A. Obukhova, B. B. Ogurlieva, A. A. Odegova, Yu. V. Yuliya V. Omarova, N. A. Omurzakova, Sh. O. Ospanova, V. A/ Pavlova, E. V. Pakhomova, L. D. Petrov, S. S. Plastinina, D. A. Platonov, V. A. Pogrebetskaya, D. V. Polyakov, E. V. Ponomarenko, L. L. Popova, A. A. Potanin, N. A. Prokofieva, Yu. D. Rabik, N. A. Rakov, A. N. Rakhimov, N. A. Rozanova, S. Serikbolkyzy, Ya. A. Sidorkina, A. A. Simonov, V. V. Skachkova, R. D. Skvortsova, D. S. Skuridin, D. V. Solovieva, I. A. Solovieva, I. M. Sukhomlinova, A. G. Sushilova, D. R. Tagaeva, E. P. Tikhonova, D. S. Tokmin, A. A. Tolmacheva, M. S. Torgunakova, K. V. Trenogina, N. A. Trostyanetskaya, D. A. Trofimov, M. A. Trubnikova, A. A. Tulichev, A. T. Tursunova, N. D. Ulanova, O. V. Fatenkov, O. V. Fedorishina, T. S. Fil, I. Yu. Fomina, I. S. Fominova, I. A. Frolova, S. M. Tsvinger, V. V. Tsoma, M. B. Cholponbaeva, T. I. Chudinovskikh, I. V. Shavrin, O. A. Shevchenko, D. R. Shikhaliev, E. A. Shishkina, K. Yu. Shishkov, S. Yu Shcherbakov, G. V. Shcherbakova, E. A. Yausheva

“…Demographic, clinical, and laboratory data, computed tomography (CT) results, information about inhospital clinical course and complications of COVID-19 during hospitalization were extracted from electronic health records using a standardized data collection form. …”
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Engagement of Indigenous peoples in commercial tobacco reform strategies: a scoping review protocol by Andrew Waa, Raglan Maddox, El-Shadan Tautolo, Michelle Kennedy, Patricia Nez Henderson, Hershel Clark, Priscilla Nez, Penney Upton, Andrew Daniel Perusco, Sydney A. Martinez, Sierra Wilcox, Jeyasakthi Venugopal

“…This review supports the global goal of eradicating commercial tobacco-related harms – reframing commercial tobacco use as a structurally imposed harm sustained by colonial and commercial forces rather than personal choice. …”
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Social Determinants of Health Associated With SARS-CoV-2 Testing and Vaccine Attitudes in a Cross-Sectional Study of Latinx Individuals in Oregon by Elizabeth L. Budd, PhD, MPH, Stephanie De Anda, PhD, Sven Halvorson, MS, Leslie D. Leve, PhD, Anne Marie Mauricio, PhD, Ellen H. McWhirter, PhD, Jorge I. Ramírez García, PhD, David S. DeGarmo, PhD

“…Multilevel structural equation path modeling addressed the nonindependence of respondents nested within 52 SARS-CoV-2 testing sites across Oregon, U.S. …”
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Case Report: Phenotypic heterogeneity within an NF1 family: assessment of the pathogenicity of a de novo c.6640dupA shift mutation and a splice variant with an epilepsy phenotype by Sijing Ren, Sijing Ren, Sijing Ren, Yanling Wang, Xinhua Tong, Xiaoyu Wu, Xiaoyu Wu, Huan Yan, Huan Yan, Qing-Xia Kong, Qing-Xia Kong, Qing-Xia Kong

“…The identified genes were validated using Sanger sequencing, and alterations in the tertiary structural physicochemical properties of the mutant proteins were analyzed using AlphaFold2 bioinformatics software.ResultsWe identified two mutation sites in the NF1 gene of the patient. …”
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The relationship between educational and scientific regulatory interventions and socio-economic development in military conflict-affected countries: A Sustainable Development Goals... by Dariusz Krawczyk, Nadiia Artyukhova, Dmytro Svynarenko, Anna Vorontsova, Artem Artyukhov, Robert Rehak, Tetiana Vasylieva

“…Type of the article: Research Article AbstractThis study investigates the structural relationships between educational and scientific regulatory interventions and socio-economic development in countries affected by armed conflict and political instability, using the framework of Sustainable Development Goals (SDGs), specifically SDG 4 (Quality Education), SDG 8 (Decent Work and Economic Growth), and SDG 9 (Industry, Innovation and Infrastructure). …”
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Evaluating the long-term impact of a distance learning course on attitudes, skills, practices, and knowledge in gender-affirming healthcare among healthcare professionals in Italy by Matteo Marconi, Ughetta Maria Favazzi, Pietro Carbone, Debora Guerrera, Angela Ruocco, Martina Manoli, Martina Manoli, Cristiana Barbati, Francesca Molinaro, Federica Maria Regini, Andrea Vittozzi, Alfonso Mazzaccara, Marina Pierdominici

“…The findings underscore the need for structural support and integrated reinforcement to embed gender-affirming care into routine practice.…”
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The risk associated with ultra-processed food intake on depressive symptoms and mental health in older adults: a target trial emulation by Belayneh Mengist, Mojtaba Lotfaliany, Julie A. Pasco, Bruno Agustini, Michael Berk, Malcolm Forbes, Melissa M. Lane, Suzanne G. Orchard, Joanne Ryan, Alice J. Owen, Robyn L. Woods, John J. McNeil, Mohammadreza Mohebbi

“…We applied inverse probability treatment weighting to balance confounders. Marginal structural models were employed to estimate the population-level average effect of intervention using generalised estimated equations. …”
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Exploring key factors related to child well-being: a community-based participatory research together with children with migration background residing in socio-economically disadvan... by Louise Burenby Yxne, Louise Burenby Yxne, Rathi Ramji, Rathi Ramji, Elisabeth Mangrio, Elisabeth Mangrio, Elisabeth Mangrio, Katarina Sjögren Forss, Katarina Sjögren Forss, Therese Sterner, Therese Sterner, Margareta Rämgård, Margareta Rämgård

“…The themes covered structural aspects, such as school, healthcare and human rights, but also more personal dimensions, like close relations and the near environment, related to Bronfenbrenner’s ecological theory of human development.ConclusionThe dialogs with the children provided a deeper understanding and a holistic view of the perceptions of children with migration backgrounds residing in socio-economically disadvantaged areas regarding essential factors for their well-being. …”
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Understanding Associations Between Patient‐Level Factors and Participation in a Breast Cancer Clinical Trial by Nicole E. Caston, Luqin Deng, Courtney P. Williams, Emily B. Levitan, Andres Azuero, Russell Griffin, Karen L. Smith, Antonio C. Wolff, Michelle E. Melisko, Eileen H. Shinn, Kathleen Gallagher, Rebekah Angove, Stephanie B. Wheeler, Gabrielle B. Rocque

“…Standardized total effects (bTot) were estimated using a prespecified Structural Equation Model with 0.1, 0.3, and 0.5 indicating weak, medium, and large magnitude, respectively. …”
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Changes in auditory cortex subregions and their prediction for sound therapy outcomes in patients with tinnitus by Ling Wang, Yu Zhang, Rui Zhao, Yan Huang, Xinghao Wang, Yuyou Huang, Jiancheng Zhang, Han Lv, Pengfei Zhao, Zhenghan Yang, Qian Chen, Zhenchang Wang

“…Objective: To examine structural and functional changes in auditory cortex(AC) subregions of patients with tinnitus and identify potential predictive indicators for sound therapy. …”
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Influencing Factors and Paths of the Coupling Relationship Between Ecosystem Services Supply–Demand and Human Well-Being in the Hexi Regions, Northwest China by Yongge Li, Wei Liu, Meng Zhu, Qi Feng, Linshan Yang, Jutao Zhang, Zhenliang Yin, Xinwei Yin

“…Here, we assessed dynamic changes in ecosystem services supply–demand, human well-being, their coupling relationships and influencing factors in the Hexi Regions by integrating remote sensing data, ecological model, ecosystem services supply–demand ratio (ESDR), coupling coordination degree (CCD) model, and the partial least squares structural equation modeling (PLS-SEM). …”
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Ecotype-specific responses of Typha domingensis to microplastics: Antioxidant defense and biochemical adaptations in wetland ecosystems by Muhammad Aqeel, Ali Noman, Saher Nawaz, Noreen Khalid, Muhammad Kashif Irshad, Muhammad Faisal Iqbal, Modhi O. Alotaibi, Motirh Al-Mutairi, Mohamed O. Alshahrani, Nahaa M. Alotaibi, Fahad Mohammed Alzuaibr

“…The inherent ability of plants to withstand microplastic (MP) stress is primarily governed by complex structural and physio-biochemical adaptations. In this study, the MP tolerance mechanisms of six naturally occurring ecotypes of Typha domingensis Pers. were assessed by examining plant pigments, ionic homeostasis, secondary metabolites, and antioxidant defense responses in MP-contaminated wetlands. …”
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Synthesis of Mg-, Al- and Mg/Al-date palm fronds modified biochars: characterization and investigations on phosphorus adsorption characteristics by Jellali, Salah, Hadroug, Samar, Al-Wardy, Malik, Hamdi, Helmi,  Al-Sabahi, Jamal, Bekri, Imene, Al-Raeesi, Ahmed, Hamdi, Wissem,  Jeguirim, Mejdi

“…In this study, three biochars were synthesized at 500 °C from pre-impregnated date palm fronds (DPFs) with 1 M solutions containing either MgCl2 (DPF-Mg-B), AlCl3 (DPF-Al-B) or a combination of MgCl2/AlCl3 (DPF-Mg/Al-B). Subsequently, the structural, textural, and surface chemistry properties of these biochars were assessed. …”
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snRNA-seq reveals subcutaneous white adipose tissue remodeling upon return to thermoneutrality after cold stimulation by Yusha Yang, Yusha Yang, Guanyu Zhang, Ting Yi, Ting Yi, Shuran Yang, Shuran Yang, Shuai Wu, Yongqiang Zhang, Li Zhang, Xi Li, Xiuxuan Wu, Xiuxuan Wu, Jun Li, Danfeng Yang

“…Subsequently, we employed single-nucleus RNA sequencing (snRNA-seq) to comprehensively characterize iWAT cellular dynamics during cold stimulation and the subsequent two-week period after the return to thermoneutrality.ResultsOur findings revealed that while iWAT phenotypically reverts to a white state after 2 weeks of rewarming, as evidenced by structural, functional, and bulk transcriptomic characteristics, significant cold-induced molecular and cellular signatures persist. …”
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Mediation of nutritional status between the number of teeth and depressive symptoms in multi-ethnic older adults from Western China by Xin Tian, Xin Xia, Huixian Li, Yuexia Hu, Yuqing Xie, Xiuying Hu, Jirong Yue, Birong Dong, Bei Wu, Yanyan Wang

“…This study aimed to investigate the role of nutritional status in mediating the number of teeth and depressive symptoms.MethodA prospective multi-ethnic baseline data of 6,632 adults aged 50 years and older was derived from the 2018 West China Health and Aging Trend study. …”
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The PA-X host shutoff site 100 V exerts a contrary effect on viral fitness of the highly pathogenic H7N9 influenza A virus in mice and chickens by Xia Chen, Ming Kong, Chunxi Ma, Manyu Zhang, Zenglei Hu, Min Gu, Xiaoquan Wang, Ruyi Gao, Shunlin Hu, Yu Chen, Xiaowen Liu, Daxin Peng, Xiufan Liu, Jiao Hu

“…By analysing the polymorphism of this residue in various subtype viruses, we found that PA-X 100 was highly variable in H7N9 viruses. Structural analysis revealed that 100 V was generally close to the PA-X endonuclease active site, which may account for its host shutoff activity. …”
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Outdoor Air Pollution Is Related to Amygdala Subregion Volume and Apportionment in Early Adolescence by Jessica Morrel, L. Nate Overholtzer, Kirthana Sukumaran, Devyn L. Cotter, Carlos Cardenas-Iniguez, J. Michael Tyszka, Joel Schwartz, Daniel A. Hackman, Jiu-Chiuan Chen, Megan M. Herting

“…Background: Outdoor air pollution exposure is associated with structural and functional brain differences and an increased risk for psychopathology. …”
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Age features of myocardial remodeling in men with ischemic chronic heart failure and renal dysfunction by D. A. Lashkul

“…However, in most studies structural remodeling of the myocardium was analyzed without sex and age characteristics. …”
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