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  1. 52181

    Systematic review of dietary salt reduction policies: Evidence for an effectiveness hierarchy? by Lirije Hyseni, Alex Elliot-Green, Ffion Lloyd-Williams, Chris Kypridemos, Martin O'Flaherty, Rory McGill, Lois Orton, Helen Bromley, Francesco P Cappuccio, Simon Capewell

    Published 2017-01-01
    “…To facilitate comparisons between the interventions, the extracted data were categorised using nine stages along the agentic/structural continuum, from "downstream": dietary counselling (for individuals, worksites or communities), through media campaigns, nutrition labelling, voluntary and mandatory reformulation, to the most "upstream" regulatory and fiscal interventions, and comprehensive strategies involving multiple components.…”
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  2. 52182

    From reality to virtuality: Unveiling Gen Z's purchasing behavior through virtual influencers in the metaverse by Tri-Quan Dang, Tan-Minh Nguyen, Phuc-Thien Tran, Tien-Thao Cong Phan, Thach-Bao Huynh, Luan-Thanh Nguyen

    Published 2025-12-01
    “…Utilizing judgmental sampling, a sample of 352 individuals with prior experience as VIs was selected to address the research objectives. The data were analyzed using a mixed-method approach, incorporating fuzzy-set Qualitative Comparative Analysis (fsQCA), Partial Least Squares Structural Equation Modeling (PLS-SEM), and Artificial Neural Networks (ANN techniques). …”
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  3. 52183

    Identification of multiple genomic alterations and prediction of neoantigens from circulating tumor cells at the single-cell level by Xiaochen Gao, Xinyu Li, Weize Xu, Ming Jiao, Yu Guo, Jiajia Wang, Weihao Wang, Jiling Feng, Qianqian Guo, Chengchao Wu, Taiyu Zhang, Yuqin Yang, Da Lin

    Published 2025-07-01
    “…In the PDX model, integrating data from seven CTCs captures 88.7% of SNPs and INDELs, and 75.0% of structural variants present in tumor tissue. …”
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    Article
  4. 52184

    Tackling Paradoxes and Double Binds for a Healthier Workplace: Insights from the Early COVID-19 Responses in Quebec and Ontario by Daniel Côté, Amelia León, Ai-Thuy Huynh, Jessica Dubé, Ellen MacEachen, Pamela Hopwood, Marie Laberge, Samantha Meyer, Shannon Majowicz, Meghan K. Crouch, Joyceline Amoako

    Published 2025-04-01
    “…We argue that PDBs represent a significant occupational health hazard for precarious workers. Addressing these structural contradictions through proactive management strategies could help mitigate workplace tensions, reduce stress, and enhance resilience in both crisis situations and regular organisational contexts. …”
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  5. 52185

    Prevalence and environmental abundance of the TSET complex in cosmopolitan algal groups by Mathias Penot-Raquin, Mandeep Sivia, Kelly M. Fafoumi, Raegan Larson, Richard G. Dorrell, Joel B. Dacks

    Published 2025-06-01
    “…Finally, diatom TSET genes are detectable in meta-transcriptomic data from Tara Oceans, suggesting functional roles in the wild. …”
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  6. 52186
  7. 52187

    The XRISM/Resolve View of the Fe K Region of Cyg X-3 by XRISM Collaboration, Marc Audard, Hisamitsu Awaki, Ralf Ballhausen, Aya Bamba, Ehud Behar, Rozenn Boissay-Malaquin, Laura Brenneman, Gregory V. Brown, Lia Corrales, Elisa Costantini, Renata Cumbee, María Díaz Trigo, Chris Done, Tadayasu Dotani, Ken Ebisawa, Megan E. Eckart, Dominique Eckert, Satoshi Eguchi, Teruaki Enoto, Yuichiro Ezoe, Adam Foster, Ryuichi Fujimoto, Yutaka Fujita, Yasushi Fukazawa, Kotaro Fukushima, Akihiro Furuzawa, Luigi Gallo, Javier A. García, Liyi Gu, Matteo Guainazzi, Kouichi Hagino, Kenji Hamaguchi, Isamu Hatsukade, Katsuhiro Hayashi, Takayuki Hayashi, Natalie Hell, Edmund Hodges-Kluck, Ann Hornschemeier, Yuto Ichinohe, Manabu Ishida, Kumi Ishikawa, Yoshitaka Ishisaki, Jelle Kaastra, Timothy Kallman, Erin Kara, Satoru Katsuda, Yoshiaki Kanemaru, Richard Kelley, Caroline Kilbourne, Shunji Kitamoto, Shogo Kobayashi, Takayoshi Kohmura, Aya Kubota, Maurice Leutenegger, Michael Loewenstein, Yoshitomo Maeda, Maxim Markevitch, Hironori Matsumoto, Kyoko Matsushita, Dan McCammon, Brian McNamara, François Mernier, Eric D. Miller, Jon M. Miller, Ikuyuki Mitsuishi, Misaki Mizumoto, Tsunefumi Mizuno, Koji Mori, Koji Mukai, Hiroshi Murakami, Richard Mushotzky, Hiroshi Nakajima, Kazuhiro Nakazawa, Jan-Uwe Ness, Kumiko Nobukawa, Masayoshi Nobukawa, Hirofumi Noda, Hirokazu Odaka, Shoji Ogawa, Anna Ogorzalek, Takashi Okajima, Naomi Ota, Stephane Paltani, Robert Petre, Paul Plucinsky, Frederick S. Porter, Katja Pottschmidt, Kosuke Sato, Toshiki Sato, Makoto Sawada, Hiromi Seta, Megumi Shidatsu, Aurora Simionescu, Randall Smith, Hiromasa Suzuki, Andrew Szymkowiak, Hiromitsu Takahashi, Mai Takeo, Toru Tamagawa, Keisuke Tamura, Takaaki Tanaka, Atsushi Tanimoto, Makoto Tashiro, Yukikatsu Terada, Yuichi Terashima, Yohko Tsuboi, Masahiro Tsujimoto, Hiroshi Tsunemi, Takeshi Tsuru, Hiroyuki Uchida, Nagomi Uchida, Yuusuke Uchida, Hideki Uchiyama, Yoshihiro Ueda, Shinichiro Uno, Jacco Vink, Shin Watanabe, Brian J. Williams, Satoshi Yamada, Shinya Yamada, Hiroya Yamaguchi, Kazutaka Yamaoka, Noriko Yamasaki, Makoto Yamauchi, Shigeo Yamauchi, Tahir Yaqoob, Tomokage Yoneyama, Tessei Yoshida, Mihoko Yukita, Irina Zhuravleva, Ryota Tomaru, Tasuku Hayashi, Tomohiro Hakamata, Daiki Miura, Karri Koljonen, Mike McCollough

    Published 2024-01-01
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  8. 52188

    Dissecting the properties of circulating IgG against streptococcal pathogens through a combined systems antigenomics-serology workflow by Alejandro Gomez Toledo, Sounak Chowdhury, Elisabeth Hjortswang, James T. Sorrentino, Nathan E. Lewis, Anna Bläckberg, Simon Ekström, Sven Kjellström, Arman Izadi, Berit Olofsson, Pontus Nordenfelt, Lars Malmström, Magnus Rasmussen, Johan Malmström

    Published 2025-02-01
    “…A selected subset of the identified antigens is then expressed recombinantly to isolate antigen-specific IgG, followed by characterization of the structural and functional properties of these antibodies. …”
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  9. 52189
  10. 52190

    Insights into Keratinocyte and Immunologic Landscape in Cutaneous Graft-Versus-Host Disease through Single-Cell Transcriptomics by Amy J. Petty, Adela Rambi Cardones, Yingai Jane Jin, Vaibhav Jain, Emily Hocke, Harsh B. Pathak, Amrita Mitra, Simon G. Gregory, M. Angelica Selim, Jennifer Y. Zhang

    Published 2025-07-01
    “…Very little is understood about the underlying pathogenesis underpinning injury at this location, especially the contribution of keratinocytes and other structural skin cells. We performed single-cell RNA sequencing to compare the transcriptome of epidermal and dermal chronic GVHD samples with that of healthy control samples. …”
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  11. 52191
  12. 52192

    ODEP-Based Robotic System for Micromanipulation and In-Flow Analysis of Primary Cells by Joanna Filippi, Paola Casti, Valentina Lacconi, Gianni Antonelli, Michele D’Orazio, Giorgia Curci, Carlo Ticconi, Rocco Rago, Massimiliano De Luca, Alessandro Pecora, Arianna Mencattini, Steven L. Neale, Luisa Campagnolo, Eugenio Martinelli

    Published 2025-01-01
    “…The induced responses obtained under time-variant ODEP stimulation reflect the cells’ chemical, morphological, and structural characteristics in an automated, flexible, and label-free manner. …”
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  13. 52193

    Evaluation of dengue virus seroprevalence in four boroughs of Mexico City among persons aged 5-35 years in 2022 by Eleazar Coba-Alcalá, Lilia Chihu-Amparán, Irma Yvonne Amaya-Larios, Susana Román-Pérez, Rene Santos-Luna, Lorena Suárez-Idueta, Sonia López-Álvarez, Cristal Morales-Trevizo, Jesús Felipe González-Roldán, Ruth Aralí Martínez-Vega, José Ramos-Castañeda

    Published 2025-02-01
    “…However, it is important to note that the structural conditions of the dwellings in these boroughs, which offer minimal barriers to vector infestation, could facilitate the establishment of local transmission under favorable conditions. …”
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    Article
  14. 52194

    Oral Small-Molecule GLP-1 Receptor Agonists: Mechanistic Insights and Emerging Therapeutic Strategies by Héctor Iván Saldívar-Cerón, Jorge Arturo Vargas-Camacho, Sonia León-Cabrera, Paola Briseño-Díaz, Ari Evelyn Castañeda-Ramírez, Axel Eduardo Muciño-Galicia, María Regina Díaz-Domínguez

    Published 2025-06-01
    “…Nevertheless, challenges persist regarding hepatic safety, pharmacodynamic variability, and limited long-term outcome data. This review integrates current structural, pharmacological, and clinical evidence, highlights key mechanistic innovations—including biased agonism, covalent binding strategies, and allosteric modulation—and discusses future directions for this rapidly evolving therapeutic class in metabolic disease management.…”
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  15. 52195

    Comprehensive Dissolution Study on Two Double Ce(IV) Phosphates with Evidence of Secondary CeO<sub>2</sub> Nanoparticle Formation by Anastasiia L. Listova, Anastasiia S. Kuzenkova, Mikhail A. Gerasimov, Elizaveta S. Kulikova, Roman D. Svetogorov, Daniil A. Novichkov, Alexei A. Averin, Vasiliy O. Yapaskurt, Anna Yu. Romanchuk, Stepan N. Kalmykov, Tatiana V. Plakhova

    Published 2025-05-01
    “…In contrast, the nanophase NaCe<sub>2</sub>(PO<sub>4</sub>)<sub>3</sub> exhibits exceptional structural and chemical stability, showing no signs of recrystallisation, phase transformation, or CeO<sub>2</sub> formation, even after extended ageing. …”
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    Article
  16. 52196

    USP7 V517F mutation as a mechanism of inhibitor resistance by Yu-Ling Miao, Fengying Fan, Yong-Jun Cheng, Li Jia, Shan-Shan Song, Xia-Juan Huan, Xu-Bin Bao, Jian Ding, Xuekui Yu, Jin-Xue He

    Published 2025-03-01
    “…We discovered a key treatment-emergent heterozygous mutation (V517F) in USP7 in the binding pocket of compounds as the primary cause of resistance to the USP7 inhibitor USP7-797. Our structural analysis, supported by AlphaFold2 predictions, indicates that the V517F mutation altered the conformation of the compound binding pocket, causing steric hindrance and reducing the affinity between USP7 and its inhibitors. …”
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    Article
  17. 52197

    Determinants of ICT Adoption and Performance in Healthcare: The Role of Individual Attributes and Organizational Contextual Factors by Abey Jose, Alejandro F. Mac Cawley, Luis Enberg Gaete, Guilherme Luz Tortorella, Roberto Vassolo, Manisha Kumar, Nick Rich, Maneesh Kumar

    Published 2025-01-01
    “…We conducted a global survey involving healthcare professionals (n =204) to understand the role of various determinants in adopting ICTs and their implications for organizational performance. Data was analyzed using Partial Least Squares Structural Equation Modelling (PLS-SEM) and multiple regression for micro-level constructs. …”
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    Article
  18. 52198

    The Expression and Molecular Roles of MAMDC2 in MSS Colorectal Cancer with a High Tumor Stromal Ratio by Yiling Liu, Shengnan Qian, Jia Wei, Jianting He, Minghui Li, Xiaobing Gao, Hong Cai, Yiqing Wang, Yue Han, Tianyuan Tan, Minhui Yang

    Published 2025-05-01
    “…The meprin/A5/PTPmu (MAM) domain, a conserved structural motif in transmembrane proteins, remains undercharacterized in CRC pathogenesis. …”
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    Article
  19. 52199

    Anthropogenic and natural influence on vegetation ecosystems from 1982 to 2023 by Teligeer Bao, Huaqiang Li, Yonghong Hao, Matthew Tom Harrison, Ke Liu, Gulnazar Ali

    Published 2025-01-01
    “…In addition, frequent land cover changes promoted the growth of greening trends (∼23%), which is linked to enhanced structural plasticity of vegetation. This effect has become more pronounced since 2000, with 92% of such changes occurring during this period. …”
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    Article
  20. 52200

    TET dioxygenases localize at splicing speckles and promote RNA splicing by Florian D. Hastert, Jasmin Weber, Christina Bauer, Andreas Zhadan, Deepanshu N. D. Singh, Thomas C. Dix, Roland Arnold, Sergey Bessonov, Matthias Soller, Heinrich Leonhardt, M. Cristina Cardoso, Maria Arroyo

    Published 2025-12-01
    “…This study explores the relationship between RNA splicing and the TET dioxygenase activity, shedding light on the role of hm5C (RNA 5-hydroxymethylcytosine), and TET proteins in RNA metabolism. Integrating data from mass spectrometry, AlphaFold structural modeling, microscopic analysis, and different functional assays, including in vitro splicing, TET proteins were found to regulate splicing. …”
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    Article