Genome-Wide Identification Analysis of the 4-Coumarate: Coa Ligase (4CL) Gene Family in <i>Brassica</i> U’s Triangle Species and Its Potential Role in the Accumulation of Flavonoid... by Mengzhen Zhang, Mengjiao Tian, Ziwuyun Weng, Yaping Yang, Nian Pan, Shulin Shen, Huiyan Zhao, Hai Du, Cunmin Qu, Nengwen Yin

“…Based on phylogenetics, gene structure, conserved motifs, chromosome localization and collinearity analysis, <i>4CLs</i> were relatively conserved in the evolution of <i>Brassica</i> U’s triangle species. …”
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Forest birds maintain body condition in Alder-leaf Birch (Betula alnoides) plantations in subtropical Asia by Wenyi Zhou, Alexandra A. Grossi, Daniel R. Gustafsson, Zhengzhen Wang, Zhuyang Zhang, Yuqing Han, Xinyi Wang, Anru Zuo, Miguel A. Acevedo, Yang Liu, Scott K. Robinson

“…Plantation forestry alters avian community assembly by creating homogeneous habitats with simplified vegetation structure. However, its effects on avian body condition remain poorly understood, despite the influence body condition has on survival and reproduction. …”
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Polar lights optimizer: A novel algorithm for accurate parameter estimation in proton exchange membrane fuel cells by Mohammad Aljaidi, Pradeep Jangir, Arpita, Sunilkumar P. Agrawal, Sundaram B. Pandya, Anil Parmar, G. Gulothungan, Ali Fayez Alkoradees, Mohammad Khishe, Reena Jangid

“…The complex multivariate structure together with nonlinear behavior of these systems makes it parameter estimation a challenging task, which negatively affects operational reliability and system lifespan. …”
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Efficacy and safety of cannabidiol in a single-center pediatric drug-resistant epilepsy cohort: a retrospective study by Ambra Butera, Ambra Butera, Giulia Spoto, Graziana Ceraolo, Maria Grella, Ivana Giunta, Maria Ludovica Albertini, Carla Consoli, Caterina Sferro, Maria Spanò, Gabriella Di Rosa, Antonio Gennaro Nicotera

“…Interestingly, brain magnetic resonance imaging revealed structural abnormalities in 5/15 patients, with 6/15 showing malformations of cortical development (4/6 responders, including 1 seizure-free).ConclusionCBD demonstrated a good safety and tolerability profile and appeared to be a promising therapeutic option for the management of DRE. …”
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Phenotypically distinguishable eosinophilic cells do not impact epithelial functions in a triple-culture in vitro intestinal model by Christoph Benkstein, Laurin Mosig, Daniel Vondran, Heidi Schlichting, Lea Kissing, Bente Wohlert, Ida Gensmer, Larissa Nogueira de Almeida, Peter König, Peter König, Kerstin Fibelkorn, Anna Kordowski, Stefanie Derer-Petersen, Christian Sina, Christian Sina, Yves Laumonnier, Yves Laumonnier

“…In-depth characterization by real-time PCR, flow cytometry, functional assay and electron microscopy showed that only butyrate and dibutyryl-cAMP generated phenotypically distinct eosinophilic cells with different activation statuses, marked by differential expression of surface markers CD11c and CD62L, increased expression of eosinophil specific genes, and development of eosinophilic structural features. Then, a triple-culture system encompassing the enterocytic cell line Caco-2 and the secretory cell line HT29-MTX complemented with eosinophilic differentiated cells was established. …”
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Feasibility study of single-image super-resolution scanning system based on deep learning for pathological diagnosis of oral epithelial dysplasia by Zhaochen Liu, Zhaochen Liu, Peiyan Wang, Peiyan Wang, Nian Deng, Hui Zhang, Hui Zhang, Fangjie Xin, Xiaofei Yu, Xiaofei Yu, Mujie Yuan, Mujie Yuan, Qiyue Yu, Yuhao Tang, Keke Dou, Jie Zhao, Bing He, Jing Deng, Jing Deng

“…Both the DS30R and Nikon scanners demonstrate high sensitivity and specificity for detecting structural features in OED pathological images; however, DS30R excels at identifying certain cellular features. …”
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Quality of Surface and Groundwater in the Sierra de Amula Region, Jalisco, Mexico by Oscar Raúl Mancilla-Villa, Fabiola Villafaña-Castillo, Álvaro Can-Chulim, Rubén Darío Guevara-Gutiérrez, José Luis Olguín-López, Elia Cruz-Crespo, Jonas Alan Luna-Fletes, Juan Uriel Avelar-Roblero

“…Each sample was evaluated for its pH, electrical conductivity, and ionic concentration (Ca²⁺, Mg²⁺, Na⁺, K⁺, CO₃²⁻, HCO₃⁻, CI⁻, SO₄²⁻). For data analysis, we determined the ionic concentrations and the salinity and sodicity indexes, including the electrical conductivity, pH, sodium adsorption ratio (SAR), and cationic ratio of soil structural stability (CROSS). …”
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Comparative genetic mapping and a consensus interspecific genetic map reveal strong synteny and collinearity within the Citrus genus by Patrick Ollitrault, Patrick Ollitrault, Barbara Hufnagel, Barbara Hufnagel, Franck Curk, Aude Perdereau, Pierre Mournet, Pierre Mournet, Maëva Miranda, Maëva Miranda, Gilles Costantino, Yann Froelicher, Yann Froelicher, Mônica Alves, Maria Angeles Forner Giner, Malcolm W. Smith, Pablo Aleza, François Luro, Nelson A. Wulff, Leandro Peña, Raphaël Morillon, Raphaël Morillon, Arnaud Lemainque

“…The consensus genetic map is a useful tool to check the accuracy of genome assemblies, identify large structural variation and focus on analyzing potential relationships with phenotypic variations. …”
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Exploring cognitive and neuroimaging profiles of dementia subtypes of individuals with dementia in the Democratic Republic of Congo by Jean Ikanga, Jean Ikanga, Saranya Sundaram Patel, Saranya Sundaram Patel, Megan Schwinne, Caterina Obenauf, Caterina Obenauf, Emmanuel Epenge, Guy Gikelekele, Nathan Tshengele, Immaculee Kavugho, Samuel Mampunza, Lelo Mananga, Charlotte E. Teunissen, Julio C. Rojas, Brandon Chan, Argentina Lario Lago, Joel H. Kramer, Adam L. Boxer, Andreas Jeromin, Emile Omba, Alvaro Alonso, Alden L. Gross

“…Core AD biomarkers (Aβ42/40 and p-tau181) and non-specific neurodegeneration biomarkers (NfL, GFAP) were measured in blood plasma. Neuroimaging structures were assessed using magnetic resonance imaging (MRI). …”
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Potential and limitations of noise-based surface-wave tomography for numerical site effect estimation: a case study in the French Rhône valley by Lavoué, François, Froment, Bérénice, Gélis, Céline, Boué, Pierre,  Chaljub, Emmanuel, Stehly, Laurent, Beauprêtre, Sophie, De Martin, Florent,  Gisselbrecht, Loïc, Pilz, Marco, Moiriat, Denis, Cushing, Edward Marc

“…The obtained ANSWT model well reproduces the main geological structures of the basin, with lateral variations of velocities at depth depicting the deeper parts of the basin. …”
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The changes in the profundal benthos during the extremely low water level in the deep lake Arakhley (Siberia) by Matafonov P.V.

“…The results of the study revealed significant fluctuations in the structure, abundance and production of zoobenthos in the profundal zone of Lake Arakhley during the extremely low-water period.…”
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Epithelial-to-mesenchymal transition is an active process in the large airways of patients with asthma-COPD overlap and partially abrogated by inhaled corticosteroid treatment: a b... by Surajit Dey, Wenying Lu, Prabuddha S. Pathinayake, Maddison Waters, Greg Haug, Josie Larby, Heinrich C. Weber, Peter A. B. Wark, Peter A. B. Wark, Mathew Suji Eapen, Sukhwinder Singh Sohal

“…Additionally, the degree of RBM fragmentation was evaluated, a key tissue structural marker of EMT.ResultsCompared to healthy controls and asthmatics, ACO had the greatest fragmentation of RBM (P &lt; 0.01). …”
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Co-circulation and genetic characterization of genotype I and II feline bocavirus strains in domestic cats from Northern Vietnam by Hieu Van Dong, Giang Thi Huong Tran, Yen Hoang Thi Nguyen, Thiet Chi Ngo, Amonpun Rattanasrisomporn, Chaiwat Boonkaewwan, Dao Anh Tran Bui, Jatuporn Rattanasrisomporn

“…DNA was extracted and screened for FBoV using conventional polymerase chain reaction targeting the non-structural (NS)-1 gene. Positive samples were subjected to Sanger sequencing, and partial NS1 sequences were analyzed using MEGA X for phylogenetic inference. …”
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Cultural and behavioral drivers of zoonotic disease transmission and persistence among diverse pastoralist communities in East Africa by Dismas C.O. Oketch, Ruth Njoroge, Tonny O. Ngage, Asha Abdikadir Omar, Abdulai Magarre, Raphael Pasha, John Gachohi, Samuel Waiguru Muriuki, Samoel Ashimosi Khamadi, Ali Duba Boru, Boku Bodha, Lydia Kilowua, Nazaria Wanja Nyaga, Humphrey Kariuki Njaanake, Eunice Kamaara, Walter Jaoko, M. Kariuki Njenga, Eric Osoro, Dalmas Omia

“…Methods This study adopts a One Health approach, employing a range of participatory methods including informal observations, “go-along interviews,” narrative-, and key informant- interviews, to explore the cultural, behavioral, and structural drivers of zoonotic disease transmission among pastoralist communities in East Africa. …”
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Efficacy and mechanisms underlying MRI-guided high-definition transcranial direct current stimulation for depression among university students: study protocol for a stepped wedge c... by Yuanle Chen, Rongxun Liu, Jinnan Yan, Peng Luo, Luhan Yang, Yongbin Wang, Guangjun Ji, Chuansheng Wang, Wei Zheng, Fei Wang, Yong Meng, Yange Wei

“…All groups will be receiving active intervention in week 5. Structural MRI data for each participant will be acquired to select the optimal electrode placement and correct for individual anatomical differences. …”
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The association between the gut microbiome and antituberculosis drug-induced liver injury by Shengfei Pei, Li Yang, Huixia Gao, Yuzhen Liu, Jianhua Lu, Er hei Dai, Chunyan Meng, Fumin Feng, Yuling Wang

“…At the same time, we constructed mouse models to explore the effects of different anti-tuberculosis drugs on gut microbiota.ResultsFollowing anti-TB treatment, we observed a decrease in microbial diversity and significant structural changes in the gut microbiota of TB patients (P &lt; 0.05). …”
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Hsa_Circ_0105596/FTO inhibits progression of Parkinson's disease by sponging miR-187-3p and regulating eEF2 by Jiahao Feng, Jin Zhao, Yong Kuang, Yuheng Zhou, Ziheng Ye, Yutong He, Dandan Chen, Li Zhang, Tingying Zhang, Qingqing Zhu, Shumin Cheng, Taoli Liu

“…The binding regulation relationship between circFTO-miR-187-3p-EEF2 was determined through structural analysis, RIP, and dual luciferase reporter assay. …”
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High-risk human papillomavirus: prevalence, association with clinical and morphological characteristics of invasive cervical cancer by L. S. Mkrtchian, V. I. Kiseleva, B. V. Boyko, L. I. Krikunova, V. A. Petrov, V. R. Gusarova, S. A. Ivanov, A. D. Kaprin, I. A. Zamulaeva

“…The etiological structure is dominated by HPV 16 (70–72 %), 18 (13–15 %), and 45 (5–7 %) types. …”
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Health poverty reduction effect of medical insurance in China’s middle-aged and elderly populations: a cross-sectional study by Haijun Yang, Rui Chen, Ye Li, Qunhong Wu, Linghan Shan, Bing Wu, Fang Yin, Yiyun Zhang, Yongqiang Lai, Xinwei Liu, Wanxin Tian, Xiyu Zhang, Yujuan Xu, Wenqing Miao, Baoguo Shi, Feifei Leng

“…Objectives In the context of demographic structure and disease spectrum changes: to study the role of the medical insurance system in providing protection and risk resilience for middle-aged and elderly vulnerable groups who are prone to impoverishment by medical expenses (IME), identify the vulnerable points and propose recommendations for improving the medical insurance system.Setting The research used data from the 2018 China Health and Retirement Longitudinal Study.Participants 9184 households were included in the research ultimately.Primary and secondary outcome measures We use the WHO’s recommended composite measure of disease-related poverty and algorithm to determine the occurrence of IME in households. …”
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Seeking Correlation Among Porin Permeabilities and Minimum Inhibitory Concentrations Through Machine Learning: A Promising Route to the Essential Molecular Descriptors by Sara Boi, Silvia Puxeddu, Ilenia Delogu, Domenica Farci, Dario Piano, Aldo Manzin, Matteo Ceccarelli, Fabrizio Angius, Mariano Andrea Scorciapino, Stefan Milenkovic

“…The automated protocol presented here could be used to inspect, in silico, many alternatives of a given molecular structure, with the output being the list of the best candidates to be then synthesized and tested. …”
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